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A Curved Four-Conductor Assembly with Larger Uniform Region

A Curved Four-Conductor Assembly with Larger Uniform Region

2023 Joint Conference of the European Frequency and Time Forum and IEEE International Frequency Control Symposium, EFTF/IFCS 2023

作者： li, Chao Hu, xuwen Sun, Fuyu liu, Jie li, Xiaofeng Zhang, Shougang National Time Service Center Chinese Academy of Sciences Xi'an China University of Chinese Academy of Sciences Beijing China

ISBN: (纸本)9798350311426

Most atomic physics setups require a uniform static magnetic field to define a quantization axis. The straight four-conductor assembly has been proven to be a useful structure for producing such a uniform static magnetic field. Here, we present an improved four-conductor assembly, where each conductor consists of one straight section and two curved sections. This hybrid structure arrangement offers more degrees of freedom than the conventional straight four-conductor assembly, enabling a larger uniform field region and better field spatial uniformity. The modified magnetic field generation structure can be used in many fields of atomic precision spectroscopy. © 2023 IEEE.

关键词： curved section four-conductor modified four-conductor static magnetic field uniformity

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Association between hypertension and prognosis of patients with COVID-19: A systematic review and meta-analysis

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CliNICAL AND EXPERIMENTAL HYPERTENSION 2022年第5期44卷 451-458页

作者： Qian, Zhe li, Zhuohong Peng, Jie Gao, Qiqing Cai, Shaohang Xu, xuwen Southern Med Univ Nanfang Hosp Dept Infect Dis 1838 Guangzhou Ave North Guangdong Kguangzhou GD Peoples R China

Background To investigate the association between hypertension and clinical outcomes, including in-hospital mortality, intensive care unit (ICU) admission, and invasive ventilation in patients with coronavirus disease 2019 (COVID-19) pneumonia. Methods We implemented a systematic search of PubMed for articles that assessed clinical outcomes of hypertensive patients infected with SARS-CoV-2. The primary outcomes evaluated included: in-hospital mortality, ICU admission, and the use of invasive ventilation. Results A total of 18 studies were included, involving 13,293 patients and covering from January 25, 2020, to April 20, 2020. The relationship between hypertension and prognosis in COVID-19 patients was evaluated. Results showed that hypertension was a risk factor for in-hospital mortality in COVID-19 patients (RR: 2.20, 95% CI, 1.83-2.65, P < .001). Moreover, patients with hypertension were more likely to be admitted to ICU (RR: 1.86, 95% CI, 1.13-3.07, P = .001) and to use invasive ventilation (RR: 2.99, 95% CI, 1.73-5.17, P < .001). Conclusions Among COVID-19 patients, those combined with hypertension had a significantly higher risk of in-hospital deaths, admission to ICU, and need for invasive ventilation.

关键词： COVID-19 epidemiology hypertension respiratory infections virology

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A Two-level Learning Approach for Achieving the Sustainable Development of Service Ecosystem

A Two-level Learning Approach for Achieving the Sustainable ...

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IEEE International Conference on Web Services (IEEE ICWS)

作者： Peng, Chao Xue, Xiao Zhang, xuwen Ji, Peilin Shen, Yifan Fang, li Feng, Zhiyong Tianjin Univ Coll Intelligence & Comp Tianjin Peoples R China Tianjin Key Lab Healthy Habitat & Mart Technol Tianjin Peoples R China Xian Univ Finance & Econ Sch Informat Xian Peoples R China

ISBN: (纸本)9798350368567;9798350368550

The governance of service ecosystem needs to balance efficiency and fairness to promote the sustainable development of the system, making it an important topic. However, service entities in the service ecosystem have autonomy and engage in dynamic game with governance strategies, leading to governance challenges. To address this issue, we model the governance process as a repeated sequential game between the governance algorithm and service entities, and propose a novel two-level learning algorithm. This algorithm considers the learning evolution of service entities and the co-evolutionary of the governance algorithm, using reinforcement learning to learn effective governance strategies while also considering the response function of service entities to balance efficiency and fairness. Combining the ideas of bilevel optimization and online learning, this algorithm effectively balances exploration (understanding the service entities' responses function) and exploitation (choosing efficient actions). We apply the algorithm to a classic service ecosystem, the ride-hailing service system, and empirically demonstrate its effectiveness in the governance task of order dispatching.

关键词： Service Ecosystem Governance Reinforcement Learning Balancing Efficiency and Fairness

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自体髂骨块植骨结合Calcar螺钉重建内侧柱治疗复杂肱骨近端骨折

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中华肩肘外科电子杂志 2021年第3期9卷 244-248页

作者：祝相如张聿达李绪文刘国明梁承志扈延龄青岛大学医学部 266073 青岛大学附属医院创伤外科 266000

目的探讨自体髂骨块移植结合Calcar螺钉重建内侧柱治疗肱骨近端骨折的临床疗效。方法回顾性分析我院自2016年1月至2018年12月收治的36例单侧复杂肱骨近端骨折患者,采用自体髂骨块移植结合Calcar螺钉治疗。随访时间12~24个月,平均17.04... 详细信息

目的探讨自体髂骨块移植结合Calcar螺钉重建内侧柱治疗肱骨近端骨折的临床疗效。方法回顾性分析我院自2016年1月至2018年12月收治的36例单侧复杂肱骨近端骨折患者,采用自体髂骨块移植结合Calcar螺钉治疗。随访时间12~24个月,平均17.04个月。记录术后3、6、12个月随访时Neer肩关节功能评分(Neer评分)和肩关节功能评分(Constant评分);采用视觉模拟评分(visual analogue scale,VAS)评估患者术后疼痛程度。分析患者骨折愈合时间、并发症发生情况及肩关节活动范围。结果36例患者均达到解剖复位,骨折平均愈合时间为3.71个月,没有患者出现肱骨头缺血性坏死及内翻塌陷。术后12个月随访时,患者Neer评分(84.64±3.40)分;Constant评分(74.26±4.70)分;VAS(1.24±0.72)分。患肩关节活动度:屈(132.58±8.01)°、伸(43.75±3.41)°、内旋(58.25±4.89)°、体侧外旋(58.89±4.83)°、外展(136.46±11.04)°。结论对于内侧粉碎性复杂肱骨近端骨折,自体髂骨块植骨结合Calcar螺钉能够重建可靠的内侧支撑,降低内翻塌陷及肱骨头缺血性坏死等并发症的风险,术后功能恢复满意。

关键词：肱骨近端骨折髂骨植骨内侧柱骨移植

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Coreactant-Free and Direct Electrochemiluminescence from Dual-Stabilizer-Capped InP/ZnS Nanocrystals: A New Route Involving n-Type Luminophore

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ANALYTICAL CHEMISTRY 2022年第2期94卷 1350-1356页

作者： Fu, li Gao, xuwen Dong, Shuangtian Jia, Jingna Xu, Yuqi Wang, Dongyang Zou, Guizheng Shandong Univ Sch Chem & Chem Engn Jinan 250100 Peoples R China

Electrochemiluminescence (ECL) is conventionally generated in either an annihilation or a coreactant route, and the overwhelming majority of ECL research is conducted in the coreactant route via oxidizing or reducing the coexisting coreactant and luminophore. The coreacant-free ECL generated via merely oxidizing the luminophore would break through the ceiling of coreactant ECL via excluding the detrimental effects of exogenous coreactant and dissolved oxygen. Herein, by exploiting the rich-electron nature of n-type nanocrystals (NCs), coreacant-free ECL is achieved via merely oxidizing 3-mercaptopropionic acid (MPA) and mercaptosuccinic acid (MSA) capped InP/ZnS NCs, i.e., InP/ZnSMPA-MSA. The electron-rich InP/ZnSMPA-MSA can be electrochemically injected with holes via two oxidative processes at around +0.75 and +1.37 V (vs Ag/AgCl), respectively, and the exogenous hole can directly combine the conduction band (CB) electron of InP/ZnSMPA-MSA, resulting in two coreactant-free ECL processes without employing any exogenous coreactant. The deprotonation process for the carboxyl group of the capping agents can provide a negatively charged surface to InP/ZnSMPA-MSA and enhance the coreactant-free ECL. The hole-injecting process at +1.37 is much stronger than that at +0.75 V and eventually enables an similar to 2000-fold enhanced ECL at +1.37 V than that at +0.75 V. The ECL at +1.37 V can be utilized for coreactant-free ECL immunoassay with prostate-specific antigen (PSA) as analyte, which exhibits an acceptable linear response from 5 ***(-1) to 1 ***(-1) with a limit of detection of 0.3 ***(-1). The coreactant-free ECL route would provide an alternative to both annihilation and coreactant routes, simplify the ECL assay procedure and deepening the ECL mechanism investigations.

关键词： Electrochemiluminescence Prostate-specific antigen

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Ru/Pt@BSA nanoparticles for efficient photo-catalytic oxidation of NAD(P)H and targeted cancer treatment under hypoxic conditions

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Chinese Chemical Letters 2023年第12期34卷 440-445页

作者： xuwen Da Xiulian liu Chao li Yatong Peng Yao Jian Wanpeng Zhou Yunli Xu Yao Wu Xuesong Wang Qianxiong Zhou Key Laboratory of Photochemical Conversion and Optoelectronic Materials Technical Institute of Physics and ChemistryChinese Academy of SciencesBeijing 100190China

Photo-catalytic oxidation of intracellular nicotinamide adenine dinucleotide(2'-phosphate)(NAD(P)H)has attracted much attention for cancer ***,the general oxygen-dependent mechanism heavily depresses the efficacy in hypoxic *** solve this problem,herein platinum nanoparticles(Pt NPs)with catalase-like(CAT-like)and catalytic H_(2)evolution activities were introduced as a powerful assistant to enhance the photo-catalytic NAD(P)H oxidation of Ru1([Ru(phen)2(PIP-OCH_(3))]^(2+),phen=1,10-phenanthroline,PIP-OCH_(3)=2-(4-methoxy phenyl)-1H-imidazo[4,5-f][1,10]phenanthroline)under hypoxic and even oxygen-free ***,Pt NPs can transform the original and in situ formed H_(2)O_(2)once again into O_(2)by the CAT-like activity,thus relieving tumor hypoxia and realizing cyclic utilization(at least in part)of the precious oxygen in ***,Pt NPs can also be served as H_(2)evolution catalysts while using Ru1 as the photosensitizer and NAD(P)H as the electron and proton *** this process,NAD(P)H is oxidized without the participation of oxygen,which can provide an effective way even under oxygen-free *** co-encapsulation of Rul and Pt NPs in bovine serum albumin(BSA)with tumor targeting ability,the resultant Ru/Pt@BSA could photo-catalyze intracellular NAD(P)H oxidation under hypoxic conditions(3%O_(2)),and exhibited an efficient and selective anticancer activity both in vitro and in *** results may provide new sights for efficient and targeted cancer treatment underhypoxic conditions.

关键词： Hypoxic Cancer treatment Photo-catalytic oxidation NAD(P)H Cyclic utilization of oxygen Pt nanoparticle

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Ternary-Host and Heterojunction Enabled Eye-Visible Elastic Mechanoluminescence from (Ca0.5Sr0.5)ZnOS/xZnS/Mn2+

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JOURNAL OF PHYSICAL CHEMISTRY C 2022年第3期126卷 1523-1530页

作者： Jia, Jingna Fu, li Gao, xuwen Dong, Shuangtian Xu, Yuqi Wang, Dongyang Zou, Guizheng Shandong Univ Sch Chem & Chem Engn Jinan 250100 Peoples R China

Mechanoluminescence (ML) is one kind of mechanical-tooptical energy conversion, and a strategy toward achieving bright elastic ML emission is strongly anticipated for ML application. Herein, a ternary-host strategy is proposed for synthesizing heterojunction ML materials with eyevisible elastic ML under an ultralow pressure of 2 N, in which ZnS, CaCO3, and SrCO3 are employed as precursors to prepare the ternary-host (Ca0.5Sr0.5)ZnOS/xZnS. Upon partially substituting the precursor ZnS with MnCO3, the Mn2+ activator could introduce luminescent centers and carrier traps into the ternary-host (Ca0.3Sr0.5)ZnOS/xZnS and enable achieving a series of (Ca0.5Sr0.5)ZnOS/xZnS/Mn2+ phosphors with bright and pressure-sensitive elastic ML. The (Ca0.5Sr0.5)ZnOS/xZnS/Mn2+ phosphors not only exhibit eyevisible red ML under ambient conditions without any preirradiation but can also display a linearly enhanced ML intensity along with the enlarged external force at a 2 N interval as well as regeneratable ML upon repetitively applying an external force 20 times. The maximum emission wavelength of ML can be conveniently modulated from 623 to 658 nm by adjusting the ZnS content of (Ca0.5Sr0.5)ZnOS/xZnS/Mn2+ phosphors.

关键词： Phosphors Transition metals Elastic materials Precursors Materials

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计算机辅助个体化钉道设计在髋臼前柱和耻骨上支骨折螺钉经皮置入中的应用

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精准医学杂志 2022年第2期37卷 161-164页

作者：祝相如陈新张成栋刘巧聪刘国明李绪文王天瑞扈延龄青岛大学附属医院创伤外科山东青岛266100 青岛市城阳区人民医院急诊外科

目的探讨术前计算机辅助个体化钉道设计在髋臼前柱和耻骨上支骨折螺钉经皮置入术中的临床应用价值。方法回顾性分析我院2018年12月—2020年12月40例(共45侧)使用通道螺钉技术进行治疗的髋臼前柱或耻骨上支骨折患者。根据术前是否使用计... 详细信息

目的探讨术前计算机辅助个体化钉道设计在髋臼前柱和耻骨上支骨折螺钉经皮置入术中的临床应用价值。方法回顾性分析我院2018年12月—2020年12月40例(共45侧)使用通道螺钉技术进行治疗的髋臼前柱或耻骨上支骨折患者。根据术前是否使用计算机进行个体化钉道设计分为计算机辅助组(A组)和常规手法组(B组),A组患者术前均使用Mimics软件进行螺钉预置入,确定螺钉入钉点、螺钉方向和螺钉长度。B组按照手术操作者经验及以往解剖学研究得出的螺钉角度进行螺钉置入,不进行个体化设计。记录两组患者术中每枚螺钉的置入时间(置钉时间)、术中透视次数(透视次数)、螺钉长度、骨折愈合时间和术后6个月随访时的髋关节Merle D′Aubignéand Postel评分与骨盆Majeed功能评分。结果A组患者置钉成功率高于B组(χ^(2)=8.666,P<0.05),A组置钉时间、透视次数较B组明显减少(t=5.910、8.138,P<0.05),A组螺钉长度较B组明显缩短(t=18.863,P<0.05),两组患者骨折愈合时间及术后6个月时功能评分比较差异无显著性(P>0.05)。结论术前使用计算机对髋臼前柱和耻骨上支螺钉位置进行个体化设计,能够在保证手术效果的前提下缩短螺钉长度,从而降低拉力螺钉置入难度,能够为无或轻度移位的髋臼前柱和耻骨上支骨折的治疗提供新的方法,且临床疗效满意。

关键词：髋臼耻骨骨折,闭合性骨折固定术,内骨螺丝拉力螺钉计算机辅助设计

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Coreactant-free and Near-Infrared Electrochemiluminescence Immunoassay with n-Type Au Nanocrystals as Luminophores

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ANALYTICAL CHEMISTRY 2022年第34期94卷 11934-11939页

作者： Fu, li liu, Xiancheng Zeng, Ying Zhang, Qingqing Zhang, Bin Gao, xuwen Zou, Guizheng Shandong Univ Sch Chem & Chem Engn Jinan 250100 Peoples R China Shenzhen Lifotron Technol Co Ltd Shenzhen 518055 Peoples R China

The electrochemiluminescence (ECL) bioassay is prominently carried out with the involvement of the coreactant. To remove the detrimental effects of the coreactant on the ECL of luminophores, herein, a promising ECL immunoassay strategy with biocompatible nanoparticles as the luminophore is proposed, which involves directly and electrochemically oxidizing the luminophore methionine-capped Au (Met@Au) nanocrystals (NCs) without the participation of any coreactant. Met@Au NCs are a kind of n-type nanoparticles, and they can be electrochemically injected with valence band (VB) holes around +0.80 and +1.10 V (vs Ag/AgCl). The electrochemically injected exogenous VB hole can recombine with the endogenous conduction band electron of Met@Au NCs and eventually bring out two coreactant-free and near-infrared ECL processes around 0.80 V (ECL-1) and 1.10 V (ECL-2). The intensity of coreactant-free ECL is primarily determined by the electrochemical oxidation-induced hole-injection process. ECL-2 is considerably stronger than ECL-1 and can be exploited for determining the carcinoembryonic antigen (CEA) in a sandwich immunoassay procedure with a linear range from 0.1 to 50 pg/mL as well as a limit of detection of 0.03 pg/mL (S/N = 3).

关键词： Immunoassay Electrochemiluminescence Infrared

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Prediction of Subsequent Vertebral Fracture After Acute Osteoporotic Fractures from Clinical and Paraspinal Muscle Features

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CALCIFIED TISSUE INTERNATIONAL 2024年第6期114卷 614-624页

作者： Xiong, Yuchao Zhang, Cici Chen, Xiaopei Wu, li liang, Shaohua Zhang, Ye Huang, Junbing Guo, Wei Zeng, xuwen Xu, Fan Jinan Univ Guangzhou Red Cross Hosp Dept Radiol Guangzhou Peoples R China

To construct a nomogram based on clinical factors and paraspinal muscle features to predict vertebral fractures occurring after acute osteoporotic vertebral compression fracture (OVCF). We retrospectively enrolled 307 patients with acute OVCF between January 2013 and August 2022, and performed magnetic resonance imaging of the L3/4 and L4/5 intervertebral discs (IVDs) to estimate the cross-sectional area (CSA) and degree of fatty infiltration (FI) of the paraspinal muscles. We also collected clinical and radiographic data. We used univariable and multivariable Cox proportional hazards models to identify factors that should be included in the predictive nomogram. Post-OVCF vertebral fracture occurred within 3, 12, and 24 months in 33, 69, and 98 out of the 307 patients (10.8%, 22.5%, and 31.9%, respectively). Multivariate analysis revealed that this event was associated with percutaneous vertebroplasty treatment, higher FI at the L3/4 IVD levels of the psoas muscle, and lower relative CSA of functional muscle at the L4/5 IVD levels of the multifidus muscle. Area under the curve values for subsequent vertebral fracture at 3, 12, and 24 months were 0.711, 0.724, and 0.737, respectively, indicating remarkable accuracy of the nomogram. We developed a model for predicting post-OVCF vertebral fracture from diagnostic information about prescribed treatment, FI at the L3/4 IVD levels of the psoas muscle, and relative CSA of functional muscle at the L4/5 IVD levels of the multifidus muscle. This model could facilitate personalized predictions and preventive strategies.

关键词： Osteoporosis Compression fracture Paraspinal muscles Fat infiltration Nomograms

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