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复合材料学报 2023年第8期40卷 4416-4439页

作者：刘勇潘子韬周宏根景旭文李国超江苏科技大学机械工程学院镇江212100

纤维增强复合材料(Fiber reinforced composites,FRC)钻削过程中产生的切削热及冷却策略对其工艺参数的优化与加工表面质量的控制起着至关重要的作用。本文从钻削热理论研究、钻削热对加工质量的影响研究、钻削热的影响因素与控制策略3... 详细信息

纤维增强复合材料(Fiber reinforced composites,FRC)钻削过程中产生的切削热及冷却策略对其工艺参数的优化与加工表面质量的控制起着至关重要的作用。本文从钻削热理论研究、钻削热对加工质量的影响研究、钻削热的影响因素与控制策略3个方面对FRC钻削热进行系统性的分析与概述。首先,综述了FRC钻孔过程中的钻削热形成机制、热传导与热损伤预测、切削热的数值模拟等理论研究。然后,阐述了FRC钻削热的主要测量方法及切削热对孔加工质量的影响,并探讨了FRC制孔的切削热影响因素及其辅助加工控制钻削热方法。最后,总结了当前FRC钻削热研究存在的问题及今后研究的重点。

关键词：纤维增强复合材料钻削热加工质量钻削刀具冷却控制方法

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High-quality chromosome-level genome assembly of the whitespotted conger (Conger myriaster)

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SCIENTIFIC DATA 2025年第1期12卷 1-9页

作者： Han, Shenglei li, Chen li, Shuo Chen, Yan Wang, Chenggang liu, Kaiqiang liu, Yuyan Wang, Hong-Yan Wang, Qian Cao, xuwen Shi, Bao Shao, Changwei Jiangsu Ocean Univ Jiangsu Key Lab Marine Bioresources & Environm Lianyungang 222005 Peoples R China Chinese Acad Fishery Sci Yellow Sea Fisheries Res Inst State Key Lab Mariculture Biobreeding & Sustainabl Qingdao 266071 Shandong Peoples R China Qingdao Marine Sci & Technol Ctr Lab Marine Fisheries Sci & Food Prod Proc Qingdao 266237 Shandong Peoples R China Haiyang Yellow Sea Fisheries Co Ltd Yantai 265100 Peoples R China Chinese Acad Fishery Sci Hebei Key Lab Bohai Sea Fish Germplasm Resources C Beidaihe Cent Expt Stn Qinhuangdao 066100 Peoples R China

The whitespotted conger (Conger myriaster) is an ecologically and economically significant benthic marine species widely distributed across East Asia's coastal waters. Despite this importance, the genomic resources for this species remain limited, hindering evolutionary and aquaculture research. Here, we present the first high-quality chromosome-level genome assembly of C. myriaster using PacBio CLR, WGS, 10X Genomics and Hi-C data. The resulting 1.09 Gb genome assembly exhibits excellent contiguity, with 97.49% of sequences anchored onto 19 chromosomes. The assembled genome achieved a BUSCO completeness stands at 98.00%, containing 34.80% repetitive sequences and 24,063 predicted protein-coding genes. This foundational genomic resource overcomes a major limitation, providing the essential framework for future investigations into the evolutionary adaptations and for the genetic improvement of C. myriaster in aquaculture.

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Polyphenols-inspired interface modification and reduced agglomeration of solid propellants via a functionalized fluorine-containing organic substance coating layer

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SURFACE & COATINGS TECHNOLOGY 2024年 477卷

作者： li, Jiao Zhang, Jian Zhang, Hongyu Wang, xuwen Lu, Taojie liang, Jiayan Yang, Yulin lin, Kaifeng Xia, Debin Harbin Inst Technol Sch Chem & Chem Engn MIIT Key Lab Crit Mat Technol New Energy Convers & Harbin 150001 Heilongjiang Peoples R China Harbin Inst Technol Sch Chem & Chem Engn Harbin 150001 Peoples R China

Interface modification of aluminum particles plays a crucial part in reducing the agglomeration during the combustion of solid propellants. In this study, the aluminum (Al) particles are pretreated with gallic acid (GA) to get Al@GA with an adhesion-favorable surface, which facilitates the further coating procedure. One new fluorine-containing organic substance is prepared, namely p-HFBA. The p-HFBA further coats the Al@GA to produce Al@GA/p-HFBA. The interface between Al@GA and the coating layer p-HFBA forms Al-F bonds and induces a pre-ignition reaction with an aluminum oxide shell. Hence, the agglomerate size of propellants containing Al@GA/p-HFBA significantly decreases from 176.30 mu m to 84.72 mu m. The agglomerates volume is reduced by approximately 97 %. Additionally, more gaseous products investigated by TG-MS provide the Al particles with greater impetus (aerodynamic forces, Fae), enabling them to leave the burning surface and reduce the residence time. The rise in Fae and drop in adhesion force (Fad) effectively reduce the agglomeration intensity according to the skeleton layer model. This work proves that interface modification can effectively enhance the combustion performance of aluminized solid propellants.

关键词： Interface modification Fluorine-containing organic substance Coatings Pre-ignition reaction Agglomeration Skeleton layer model

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Aquaponics model can provide better productivity: Microorganisms affect the growth and health of tilapia

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AQUACULTURE REPORTS 2025年 40卷

作者： Fan, Dingyue Xu, Huimin Meng, Shunlong Fan, limin Song, Chao Qiu, liping li, Dandan Fang, Longxiang liu, Zhuping Bing, xuwen Shanghai Ocean Univ Coll Fisheries & Life Sci Shanghai Peoples R China Chinese Acad Fishery Sci Freshwater Fisheries Res Ctr Sci Observing & Expt Stn Fishery Resources & Envir Wuxi 214081 Peoples R China

Aquaponics is a novel ecological agricultural strategy that combines aquaculture and hydroponic cultivation. The relationships between fish immunological and digestive functions, water quality, and bacterial populations were not well understood. This study aims to investigate the effects of aquaponics on aquaculture water quality, fish growth performance, and fish health, as well as exploring the roles of microbial taxa in these processes. In the present study, three aquaponics systems were established, and three same sized recirculating aquaculture systems (RAS) were constructed to act as controls. To evaluate bacterial community diversity and compositions across different microhabitats in the two systems, we used amplicon-based high-throughput sequencing technique targeting the 16S rRNA gene. In aquaponics, fish had a much greater nitrogen utilization rate, weight gain rate (WGR), feed conversion ratio (FCR), and specific growth rate (SGR) than in controls. The activities of alkaline phosphatase (AKP), acid phosphatase (ACP), lysozyme (LYS), lipase (LPS), and trypsin (TRP) in tissues, all of which are indicators of fish health, were significantly greater in aquaponics than in controls. Aquaponics effectively lowered chlorophyll-a levels while having little effect on other water quality metrics, indicating their potential for better algae control. Water quality measures such as dissolved organic carbon, chlorophyll-a, dissolved oxygen, and ammonia nitrogen had a substantial impact on the fish's immunological and digestive capabilities. In terms of microbial influence, particular gut bacteria-such as the bacterial orders Pseudomonadales, Caulobacterales, Defluviicoccales, Exiguobacterales, and Gemmatales-have been identified as influencing various functions in fish. Among these bacterial orders, we found that Pseudomonadales and Exiguobacterales were more abundant in aquaponics than control systems. This study demonstrated that aquaponics can increase fish health an

关键词： Aquaponics Tilapia growth and health Water quality Microbial community

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Platelet microparticles-derived miR-25-3p promotes the hepatocyte proliferation and cell autophagy via reducing B-cell translocation gene 2

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JOURNAL OF CELLULAR BIOCHEMISTRY 2020年第12期121卷 4959-4973页

作者： Xu, Yuyuan li, Wenfei liang, Guangyu Peng, Jie Xu, xuwen Southern Med Univ Nanfang Hosp Dept Infect Dis 1838 North Guangzhou Ave Guangzhou 510515 Guandong Peoples R China

Platelets are critical regulators of liver regeneration, but the mechanisms are still not fully understood. Platelets have been shown to contain a wide variety of microRNAs (miRNAs) and play an important role in many diseases. However, the mechanism that how the platelet microparticles (PMPs)-derived miRNA regulate the hepatocyte proliferation is not very clear. In this study, we have successfully isolated and identified PMPs. We also found that PMPs, which could be well integrated into the HHL-5 cells, could upregulate the level of miR-25-3p in HHL-5 cells. Meanwhile, we found that PMPs-derived miR-25-3p promoted HHL-5 cells proliferation by accelerating cells into the S phase, and enhanced the autophagy by increasing the LC3II expression and reducing the P62 expression. Then, we proved that the miR-25-3p could target the B-cell translocation gene 2 (BTG2) and downregulate the expression levels of the BTG2 gene in HHL-5 cells. In addition, the overexpression of BTG2 significantly inhibited the proliferation and autophagy abilities of HHL-5 cells, while cotransfected miR-25-3p mimics or PMPs could partially rescue HHL-5 cells proliferation and autophagy. Furthermore, we proved that PMPs accelerated hepatocyte proliferation by regulating autophagy pathways. Therefore, PMPs-derived miR-25-3p promoted HHL-5 cell proliferation and autophagy by targeting BTG2, which may be a new therapeutic method for liver regeneration.

关键词： autophagy B-cell translocation gene 2 liver regeneration miR-25-3p platelet microparticles proliferation

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60岁以下人群急性主动脉夹层CT平扫影像征象的初步研究

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中国继续医学教育 2018年第27期10卷 51-53页

作者：李颖李旭文内蒙古民族大学第二临床医学院/内蒙古林业总医院医学影像科内蒙古牙克石022150 上海市松江区泗泾医院放射科上海201600

目的总结60岁以下人群(不包括60岁,下文以<60岁表示)急性主动脉夹层多排螺旋CT平扫诊断征象,提高<60岁人群主动脉夹层CT平扫诊断准确率。方法回顾分析本院2013年1月—2017年12月主要因突发急性胸痛、腹痛等病因急诊就诊的患者44例... 详细信息

目的总结60岁以下人群(不包括60岁,下文以<60岁表示)急性主动脉夹层多排螺旋CT平扫诊断征象,提高<60岁人群主动脉夹层CT平扫诊断准确率。方法回顾分析本院2013年1月—2017年12月主要因突发急性胸痛、腹痛等病因急诊就诊的患者44例。<60岁年龄组14例,年龄最小45岁,最大54岁,平均(49.8±3.2)岁。≥60岁年龄组30例,年龄最小61岁,最大81岁,平均(71.2±6.3)岁。均行64排螺旋CT胸部扫描或胸腹部联扫,平扫检查后当日至一周内在本院行CTA检查明确诊断为主动脉夹层。对44例确诊主动脉夹层患者平扫诊断征象进行数据总结,结果使用SPSS软件进行χ~2检验。结果 (1)主动脉增粗,(2)钙斑内移,(3)主动脉内密度不均,(4)主动脉腔见内膜片影,(5)心包积液,(6)胸膜增厚,(7)胸腔积液,(8)背侧肺野高密度影,以上诊断征象经统计学分析,(2)～(8)的诊断征象在≥60岁年龄组与<60岁年龄组间差异具有统计学意义,P<0.05。征象(2)(3)(7)在≥60岁年龄组发生率较高;征象(4)(5)(6)(8)在<60岁年龄组发生率较高。结论 <60岁年龄组主动脉夹层主要表现为主动脉腔内见内膜片影、心包积液、胸膜增厚、背侧肺野高密度影四个征象,以上四个征象对<60岁人群主动脉夹层平扫诊断更具有特征性。

关键词：急性主动脉夹层 <60岁内膜片影心包积液胸膜增厚背侧肺野高密度影

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VDE-SAT下行链路信道建模方法

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中国科学院大学学报（中英文） 2024年第2期41卷 249-256页

作者：丁港辉李宗旺谢卓辰梁旭文中国科学院微小卫星创新研究院中国科学院微小卫星重点实验室上海201203 中国科学院大学北京100049

海面的散射特性导致VDES海上通信信道模型复杂多变,在VDE-SAT下行链路中,低仰角通信导致海浪反射带来的多径效应更加严重。针对此问题,提出一种基于球坐标系的VDE-SAT下行链路信道建模方法,根据不同海情级分析海浪反射对于信号接收特性... 详细信息

海面的散射特性导致VDES海上通信信道模型复杂多变,在VDE-SAT下行链路中,低仰角通信导致海浪反射带来的多径效应更加严重。针对此问题,提出一种基于球坐标系的VDE-SAT下行链路信道建模方法,根据不同海情级分析海浪反射对于信号接收特性的影响。首先,将海面散射特性的统计结果参数化,结合地球曲率的影响,建立基于球坐标系的星船通信几何模型,基于此,得到海面有效漫反射区。其次,建立星船通信链路的信号多径传播模型,基于G1139协议,根据各个路径的信道参数分析接收信号的功率分布,以及不同海情级下信号的接收特性。仿真结果表明:在海况较好时,该多径信道以镜面反射为主;海况较差时,以漫反射为主。相比于卷积码,Turbo码的抗多径性能更优。

关键词： VDE-SAT 信道模型卫星通信多径效应

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Effects of Micellization Behavior on the Interfacial Adsorption in Binary Anionic/Nonionic Surfactant Systems: A Molecular Simulation Study

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LANGMUIR 2021年第40期37卷 11835-11843页

作者： lian, Peng Jia, Han Yan, Hui Yuan, Jie Tang, Hongtao li, Zhe Fan, Fangning Qin, xuwen Lv, Kaihe liu, Dexin China Univ Petr East China Sch Petr Engn Qingdao 266580 Peoples R China China Univ Petr East China Sch Petr Engn Shandong Key Lab Oilfield Chem Qingdao 266580 Peoples R China Liaocheng Univ Sch Pharmaceut Sci Liaocheng 252059 Shandong Peoples R China SINOPEC Shengli Oilfield Co Shengli Oil Prod Plant Dongying 257000 Peoples R China

A surfactant interfacial adsorption process is highly associated with its micellization behaviors in the water phase, which is of great fundamental and practical significance in enhanced oil recovery. In this paper, the typical anionic surfactant 1-dodecanesulfonic acid sodium (DAS) and nonionic surfactants octylphenol polyoxyethylene ether-n (OP-n, n = 1, 5, and 10) are introduced to investigate their micellization behavior and interfacial adsorption process via molecular dynamics simulation. Number density profiles reveal that the additional OP5 molecules in the water phase generate the mixed micelle with DAS molecules and greatly promote its interfacial adsorption. Interaction energy calculation is employed to confirm the interaction of anionic/nonionic surfactants in the mixed micelle. Then, the radial distribution function, solvent-accessible surface area, and solvation free energy are calculated to further explore and verify the adsorption mechanism of the mixed micelle. It is found that the nonionic surfactant obviously decreases the hydrophilicity of the mixed micelle in the water phase, which should be responsible for its intensive tendency of the interfacial adsorption.

关键词： Adsorption Molecules Micelles Surfactants Water

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SERIES OF DIMERIC INDOLE ALKALOID COMPOUNDS, PREPARATION METHOD THEREFOR AND USE OF SAME IN PREPARATION OF ANTIBACTERIAL DRUGS

SERIES OF DIMERIC INDOLE ALKALOID COMPOUNDS, PREPARATION MET...

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作者： GUO, Yuewei LAN, Lefu li, xuwen CHEN, Feifei liU, Jin

标准号: WO2019072112(A1)

The present invention falls within in the fields of organic synthesis and pharmaceutical chemistry. In particular, the present invention relates to a series of dimeric indole alkaloid compounds as shown in structural general formula I, preparation methods therefor and the use of same in the preparation of antibacterial drugs. After same undergo in vitro activity screening, the results show that such compounds have strong antibacterial activity, in particular have specific inhibitory effects on gram-positive bacteria, such as strains of staphylococcus, bacillus and enterococcus, and related drug-resistant strains thereof, and can be used as the lead compounds for developing new antibacterial drugs.

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Multi-scale Feature Fusion Extraction Structure for the Leather Defect Detection Algorithm

Multi-scale Feature Fusion Extraction Structure for the Leat...

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Pattern Recognition and Artificial Intelligence (PRAI), International Conference on

作者： xuwen He Hao li Zihan Huang Xiaorui Xiong Yifan liu Yuting Yao School of Mathematics and Computer Science Wuhan Polytechnic University Wuhan China

Detection of surface defects using computer vision is a pivotal technology for achieving intelligent manufacturing. Leather products are one of the most widely traded goods in the world, and automatic identification, localization, and detection of surface defects in leather are indispensable for achieving intelligent manufacturing of leather products. This research paper proposes FG-DETR, a multi-scale feature fusion extraction structure for small target detection algorithms. Given the recent success of deep learning methods in various related fields and that certain defects and flaws in leather pictures in our dataset are relatively small. FG-DETR is based on DETR with some improvements as follows, Initially, DETR's ResNet50 network performs feature extraction on the original image and produces four scales of feature maps. Second, we apply a modified Feature Pyramid Network (FPN) to downsample and upsample the four scales of feature maps, followed by the fusion and output of a single feature map. A Gaussian kernel and output then process the fused feature maps as the final feature maps. Finally, the feature maps are merged with the position encoding information and combined into the Transformer encoder-decoder architecture, resulting in the detection outcomes through the Position-wise Feed-Forward Networks (FFN). In our leather dataset, the FG-DETR model is more effective in detecting small targets than DETR, as our leather images are large, and the original DETR is nearly ineffective for images with relatively small defects. The average detection accuracy of medium and large targets also improved, with a 7.6 percentage point improvement at AP50. The experimental findings demonstrate that the multi-scale feature fusion extraction structure significantly enhances the detection accuracy of DETR.

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