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SSRN 2023年

作者： Zhou, Kai wu, Xin Zeng, Hui Che, Xingbang Wang, xuwen Xiao, Han Yang, Can Yang, Huan Ruan, Shuangchen Li, Chunbo Sino-German College of Intelligent Manufacturing Shenzhen Technology University Shenzhen518118 China School of Remote Sensing and Information Engineering Wuhan University Wuhan430079 China DH Automation Technology Co. Ltd Shenzhen518110 China Key Laboratory of Advanced Optical Precision Manufacturing Technology Guangdong Higher Education Institutes Shenzhen Technology University Shenzhen518118 China

Metal surface coloring process is considered as a process with strong technical influence because its’ advantage in improving the appearance of metal, identifying metal products with information, preventing corrosion of metal substrate, excellent color stability and other characteristics. Laser induced metal coloring is expected to become a metal coloring process with stability and efficiency for its quickly response in producing bright colors on the metal matrix by simply setting the process parameters. The process is simple and with excellent efficiency and accuracy. At present, in the field of laser induced coloring, the main method is to find the corresponding relationship between laser energy density and color formation with a large number of laser parameters, the main limit in this method comes from lacking convenience to reproduce color s within costing a great deal of time. How to establish the nonlinear relationship between metal coloring process and specific color formation is still a challenge. Here, we observed thousands of laser-induced Ti-6Al-4V coloring test data in efficient way, based on the color evaluation index of CIE1976 color system and the theory of Multilayer Perceptron algorithm. It is proved that the color produced by the laser is highly matched with the color predicted by training of Multi-layer Perceptron algorithm. The precision difference brought by different algorithm strategies is compared, attempted to find the algorithm strategy that is capable of predicting color formation with high accuracy. This study provides a feasible method for the application of laser coloring to the industrial field. © 2023, The Authors. All rights reserved.

关键词： Neural networks

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Advances in Multimodal Imaging Techniques for Evaluating and Predicting the Efficacy of Immunotherapy for NSCLC

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Cancer Management and Research 2025年 17卷 1073-1086页

作者： Jingyi Liu Mei Xie Jing Shen Jie Yao xuwen Lin Xinyu Bao Xin Zhang Yiran Liang Yun Yang Gege Jiang Ximeng Diao Wenya Han Hai Du Xinying Xue Jianlin wu Department of Radiology Affiliated Zhongshan Hospital of Dalian University Dalian 116001 People’s Republic of China Department of Respiratory and Critical Care Emergency and Critical Care Medical Center Beijing Shijitan Hospital Capital Medical University Beijing 100038 People’s Republic of China Department of Respiratory and Critical Care Affiliated Hospital of Shandong Second Medical University Weifang People’s Republic of China Department of Respiratory and Critical Care Medicine Taihe Hospital Hubei University of Medicine Shiyan 442000 People’s Republic of China Ordos Central Hospital Ordos City 017000 People’s Republic of China Department of Respiratory and Critical Care Xuanwu Hospital Capital Medical University Beijing 100038 People’s Republic of China

Immunotherapy has emerged as a transformative treatment for non-small cell lung cancer (NSCLC), yet its clinical benefits remain variable among patients. Early and accurate evaluation of treatment response is critical to guide therapeutic adjustments and improve outcomes. This review synthesizes recent advancements in multimodal imaging techniques—computed tomography (CT), positron emission tomography (PET)/CT, magnetic resonance imaging (MRI), and radiomics—for evaluating and predicting immunotherapy efficacy in NSCLC. We analyze the strengths and limitations of conventional morphological criteria (eg, RECIST, iRECIST) and highlight emerging quantitative biomarkers, including CT texture analysis, metabolic parameters (MTV, TLG), and diffusion-weighted MRI metrics. Notably, radiomics demonstrates promise in decoding tumor heterogeneity, PD-L1 expression, and immune microenvironment features, while immuno-PET probes targeting immune checkpoints offer novel insights into immune activity in vivo. Challenges such as pseudo-progression, nodal immune flare, and discrepancies between imaging responses and pathological responses are critically discussed. By integrating morphological, metabolic, and microenvironmental data, multimodal imaging enhances precision in patient stratification and therapeutic monitoring. Future research should prioritize multicenter, AI-driven radiomics validation and targeted tracer development to optimize NSCLC immunotherapy management. This review provides clinicians and researchers with new directions for utilizing multimodal imaging techniques in developing personalized treatment strategies.

关键词： non-small cell lung cancer immunotherapy efficacy prediction CT PET MRI

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纺织品行业的全球竞争格局与可持续发展路径探讨

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西部皮革 2025年第5期47卷 5-7页

作者：曹蓄温李淼吴玥史咏洁常州纺织服装职业技术学院马来亚大学

随着全球化的快速推进和国际贸易的兴旺发展，纺织品行业作为全球贸易的重要领域，其格局已经历了显著转变。作为全球纺织品生产和出口的主导国家，中国企业正面临日益复杂的国际市场环境。中国纺织行业通过优化产业结构和转变增长动力... 详细信息

随着全球化的快速推进和国际贸易的兴旺发展，纺织品行业作为全球贸易的重要领域，其格局已经历了显著转变。作为全球纺织品生产和出口的主导国家，中国企业正面临日益复杂的国际市场环境。中国纺织行业通过优化产业结构和转变增长动力，加速技术改造和升级，不断提升其国际竞争力，并积极融入全球供应链。文章从国际经济与贸易的视角出发，深入分析了纺织品行业的全球竞争态势、国际贸易政策，以及企业如何在不断变化的市场中实现发展与突破。

关键词：纺织品行业全球化可持续发展

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架空输电线路体系强度匹配设计方法

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高电压技术 2021年第12期47卷 4306-4313页

作者：吴静李峰安旭文李茂华侯建国中国电力科学研究院有限公司北京100055 国家电网有限公司北京100031 武汉大学土木建筑工程学院武汉430072

为了整体把握架空输电线路体系的可靠性,综合考虑了现行输电线路各组件的安全度水平、建造成本、破坏修复时间和费用,采用强度匹配理论开展了架空输电线路体系强度匹配设计方法研究,提出了输电线路体系各组件的5种失效顺序、体系的强度... 详细信息

为了整体把握架空输电线路体系的可靠性,综合考虑了现行输电线路各组件的安全度水平、建造成本、破坏修复时间和费用,采用强度匹配理论开展了架空输电线路体系强度匹配设计方法研究,提出了输电线路体系各组件的5种失效顺序、体系的强度匹配设计方法及其相应的匹配系数。所提方法与现行设计方法的对比分析表明,大部分体系组件的安全度水平可与现行规范保持一致。采用强度匹配设计方法可实现不同架空输电线路体系的差异化匹配设计。

关键词：架空输电线路体系可靠性强度匹配失效顺序设计方法安全度水平

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Effect of pre-coagulation on catalytic ozonation in the tertiary treatment of coking wastewater: Kinetic and ozone consumption analysis

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JOURNAL OF WATER PROCESS ENGINEERING 2022年 48卷

作者： Wang, Hao Zhang, Siyu He, Can Yuan, Run wu, Xu Guo, Shaoqing He, xuwen Van Hulle, Stijn W. H. China Univ Min & Technol Beijing Sch Chem & Environm Engn Beijing 100083 Peoples R China Univ Ghent Dept Green Chem & Technol LIWET Campus KortrijkGraaf Karel De Goedelaan 5 B-8500 Kortrijk Belgium Katholieke Univ Leuven Dept Chem Engn PET Lab J De Nayerlaan 5 B-2860 St Katelijne Waver Belgium

The ozone-based advanced oxidation process in wastewater effluent degrades refractory organics efficiently and significantly. Nevertheless, high energy consumption is a challenge that hinders its widespread application. In this work, the pre-coagulation enhanced catalytic ozonation process for the treatment of biologically treated coking wastewater (BTCW) was investigated. The chemical oxygen demand (COD) removal results indicated that catalytic ozonation has an inadequate removal effect on the organic pollutants in BTCW. Moreover, the two-stage degradation occurred in the COD ozonation process, of which the slow reaction rate in the second stage was the main reason that limited its overall effect. The pre-coagulation overcame the obstacle of the limited effect of catalytic ozonation treatment of BTCW because of its ability to remove hydrophobic organics. The combination of pre-coagulation with catalytic ozonation could increase the COD removal efficiency from 45% to 69% compared with catalytic ozonation alone. There was a linear relationship between specific ozone consumption and ozone dosage regardless of whether BTCW was subjected to pre-coagulation. The fact that the slope of this linear relationship with pre-coagulation was much smaller than that without pre-coagulation. It indicates that pre-coagulation could significantly reduce ozone consumption. The primary role of pre-coagulation was to reduce ozone consumption considerably in the second stage of the ozonation process. The ozone consumption per unit mass of COD in the second stage reached 24.3 gO(3)/gCOD without pre-coagulation, while that was only 6.8 gO(3)/gCOD with pre-coagulation.

关键词： Coking wastewater Catalytic ozonation Pre-coagulation Kinetic model Consumption analysis

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CHANGES IN GAUSSIAN MODELING PARAMETERS OF PPG PULSE DURING HEALTHY PREGNANCY

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JOURNAL OF MECHANICS IN MEDICINE AND BIOLOGY 2021年第5期21卷 2140001-2140001页

作者： Meng, Yu Yang, Lin Zhang, Song wu, Guanghui Liu, Xiaohong Hao, Dongmei Yang, Yimin Li, xuwen Beijing Univ Technol Fac Environm & Life Beijing 100024 Peoples R China Capital Med Univ Beijing Anzhen Hosp Beijing Inst Heart Lung & Blood Vessel Dis Beijing 100029 Peoples R China Beijing Yes Med Devices Co Ltd Beijing 100152 Peoples R China

We used Gaussian modeling to depict the changes in finger photoplethysmographic (PPG) pulse during pregnancy in healthy women. We enrolled 70 healthy pregnant women and recorded their PPG pulses in 11-13 gestational weeks, 20-22 gestational weeks, and 37-39 gestational weeks. Three independent positive Gaussian functions were utilized to decompose the pulses, and each Gaussian function extracted three key parameters: the peak amplitude (H), the peak position (T), and the half-width (W). The method of ANOVA and post-hoc multiple comparisons of mathematical statistics were utilized to study the differences of these parameters between the three trimesters. We found that in the first trimester H-1 increased significantly (H-1 : 49.7 +/- 10.3 versus 52.9 +/- 6.9, p < 0.05). T-2 and T-3 increased in the first trimester (T-2 : 28.1 +/- 2.8 versus 28.4 +/- 2.2, p > 0.05;T-3: 54.3 +/- 4.2 versus 56.3 +/- 4.3, p < 0.01), then decreased significantly (T-2 : 28.4 +/- 2.2 versus 27.3 +/- 2.2, T-3: 56.3 +/- 4.3 versus 54.7 +/- 5.2, p < 0.05). H-1 is associated with cardiac output, and T-2 and T-3 are associated with peripheral vascular resistance. The results of this study were consistent with the conclusion that healthy pregnant women exhibited high flow state of the cardiovascular system and their peripheral vascular resistance decreased first and then gradually recovered during pregnancy. This study indicated that PPG pulse could also reflect the changes in the maternal cardiovascular system during pregnancy.

关键词： PPG pulse healthy pregnant women Gaussian modeling parameters

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分子动力学模拟阴离子/两性离子表面活性剂在油-水界面的分子行为及协同效应

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石油学报（石油加工） 2021年第4期37卷 831-839页

作者：吴姁夏瑜苑莲花员润何绪文中国矿业大学(北京)化学与环境工程学院北京100083

采用分子动力学模拟方法研究了表面活性剂十二烷基硫酸钠(SDS)/十二烷基磺丙基甜菜碱(SB12-3)混合体系在油-水界面的聚集行为以及SDS与SB12-3的协同作用。通过密度分布、界面厚度、界面形成能来分析油-水界面性质,当n(SDS)/n(SB12-3)=1/... 详细信息

采用分子动力学模拟方法研究了表面活性剂十二烷基硫酸钠(SDS)/十二烷基磺丙基甜菜碱(SB12-3)混合体系在油-水界面的聚集行为以及SDS与SB12-3的协同作用。通过密度分布、界面厚度、界面形成能来分析油-水界面性质,当n(SDS)/n(SB12-3)=1/1时,协同效应达到最大,即混合体系的界面形成能(E_(IF))达到-640.959 kJ/mol。通过亲水基团的径向分布函数和氢键数目研究了SDS和SB12-3的亲水效应,发现SB12-3的亲水基团与水分子优先形成氢键,且形成氢键数目(12.555)大于SDS与水之间的氢键数目(8.968),SB12-3的亲水性更好;通过表面活性剂头基与尾链之间的夹角和疏水尾链序参数研究了2种表面活性剂的疏水性能,发现SDS烃链在油相中夹角(114.368°)大于SB12-3在油相中角度(111.903°),证明SDS拉伸程度好,表现出良好的疏水性能,2种表面活性剂的协同作用良好。

关键词：分子动力学模拟油-水界面十二烷基硫酸钠十二烷基磺丙基甜菜碱

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大直径钢筋装配式混凝土足尺框架拟动力试验研究

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建筑结构学报 2025年第1期46卷 19-29页

作者：张旭乔肖绪文朱彤张勇波张磊张志超丛峻武朝军李罡中建工程试验检测(北京)有限公司北京101300 中国建筑股份有限公司技术中心北京101300 中建工程产业技术研究院有限公司北京101300 中国建筑第六工程局有限公司天津300171 济南交通发展投资有限公司山东济南250013 济南轨道交通集团有限公司山东济南250013

为研究大直径钢筋装配式混凝土框架抗震性能,对三层两跨大直径钢筋装配式混凝土足尺框架进行拟动力试验,分析框架在地震设防三标准下的破坏形态、动力时程反应及抗震性能指标。研究结果表明:多遇地震作用下,框架并未出现裂缝,处于弹性状... 详细信息

为研究大直径钢筋装配式混凝土框架抗震性能,对三层两跨大直径钢筋装配式混凝土足尺框架进行拟动力试验,分析框架在地震设防三标准下的破坏形态、动力时程反应及抗震性能指标。研究结果表明:多遇地震作用下,框架并未出现裂缝,处于弹性状态;设防地震作用下,框架出现微裂缝,试验结束时裂缝闭合;罕遇地震作用后,框架进入弹塑性状态。以承载力和残余变形确定使用性能时,多遇地震作用下达到抗震性能3(完好);设防地震作用下,达到抗震性能4(轻到中等破坏);罕遇地震作用下,达到抗震性能4(不严重破坏);各地震工况下,框架底部剪力-层间位移角曲线基本呈线性,具有较好的滞回性能;罕遇地震后,柱主筋均未屈服,一、二层梁端主筋屈服,实现了“强柱弱梁”的设计目标。同时,对大直径钢筋框架和普通直径钢筋框架进行有限元对比分析,两者各层层间位移以及层间剪力均值相对误差分别为-5.73%和-1.41%,动力性能接近。

关键词：混凝土框架大直径钢筋装配式拟动力试验抗震性能

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The Role of MbEGS1 and MbEGS2 in Methyleugenol Biosynthesis by Melaleuca bracteata

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SSRN 2022年

作者： Lin, Yongsheng Qiu, Ziwen Lin, Xiaojie wu, Yingxiang Niu, Xianqian Yin, Guanwen Shao, Dandan Xiang, xuwen Li, Yongyu Yang, Chao College of Horticulture Fujian Agriculture and Forestry University Fuzhou350002 China Institute of Natural Products of Horticultural Plants Fujian Agriculture and Forestry University Fuzhou350002 China Qingyuan Agricultural Science and Technology Extension Service Center Qingyuan511518 China Fujian Institute of Tropical Crops Zhangzhou363001 China

Many aromatic plant volatile compounds contain methyleugenol, which is an attractant for insect pollination and has antibacterial, antioxidant, and other properties. The essential oil of Melaleuca bracteata leaves contains 90.46% methyleugenol, which is an ideal material for studying the biosynthetic pathway of methyleugenol, where eugenol synthase (EGS) is one of the key enzymes involved in the synthesis of methyleugenol. We recently reported two eugenol synthase genes (MbEGS1 and MbEGS2) present in M. bracteata, where MbEGS1 and MbEGS2 were mainly expressed in flowers, followed by leaves, and had the lowest expression levels in stems. In this study, the functions of MbEGS1 and MbEGS2 in the biosynthesis of methyleugenol were investigated using transient gene expression technology and virus-induced gene silencing (VIGS) technology in M. bracteata. Here, in the MbEGSs genes overexpression group, the transcription levels of the MbEGS1 gene and MbEGS2 gene were increased 13.46 times and 12.47 times, respectively, while the methyleugenol levels increased 18.68% and 16.48%. We further verified the function of the MbEGSs genes by using VIGS, as the transcript levels of the MbEGS1 and MbEGS2 genes were downregulated by 79.48% and 90.35%, respectively, and the methyleugenol content in M. bracteata decreased by 28.04% and 19.45%, respectively. The results indicated that the MbEGS1 and MbEGS2 genes were involved in the biosynthesis of methyleugenol, and the transcript levels of the MbEGS1 and MbEGS2 genes correlated with the methyleugenol content in M. bracteata. © 2022, The Authors. All rights reserved.

关键词： Biosynthesis

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Effect of Pre-Coagulation on Catalytic Ozonation in the Tertiary Treatment of Coking Wastewater: Kinetic and Ozone Consumption Analysis

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SSRN 2022年

作者： Wang, Hao Zhang, Siyu He, Can Yuan, Run wu, Xu Guo, Shaoqing He, xuwen Van Hulle, Stijn W.H. Beijing100083 China LIWET Department of Green Chemistry and Technology Ghent University Campus Kortrijk Graaf Karel De Goedelaan 5 KortrijkB-8500 Belgium KU Leuven Department of Chemical Engineering PET Lab J. De Nayerlaan 5 Sint-Katelijne-WaverB-2860 Belgium

The ozone-based advanced oxidation process in wastewater effluent degrades refractory organics efficiently and significantly. Nevertheless, high energy consumption is a challenge that hinders its widespread application. In this work, the pre-coagulation enhanced catalytic ozonation process for the treatment of biologically treated coking wastewater (BTCW) was investigated. The chemical oxygen demand (COD) removal results indicated that catalytic ozonation has an inadequate removal effect on the organic pollutants in BTCW. Moreover, the two-stage degradation occurred in the COD ozonation process, of which the slow reaction rate in the second stage was the main reason that limited its overall effect. The pre-coagulation overcame the obstacle of the limited effect of catalytic ozonation treatment of BTCW because of its ability to remove hydrophobic organics. The combination of pre-coagulation and catalytic ozonation was significantly beneficial for reducing the COD content in BTCW and increased the COD removal of BTCW from 45% to 69%. There was a linear relationship between specific ozone consumption and ozone dosage regardless of whether BTCW was subjected to pre-coagulation. The fact that the slope of this linear relationship with pre-coagulation was much smaller than that without pre-coagulation. It indicates that pre-coagulation could significantly reduce ozone consumption. The primary role of pre-coagulation was to reduce ozone consumption considerably in the second stage of the ozonation process. The ozone consumption per unit mass of COD in the second stage reached 24.3 gO 3 /gCOD without pre-coagulation, while that was only 6.8 gO 3 /gCOD with pre-coagulation. © 2022, The Authors. All rights reserved.

关键词： Chemical oxygen demand

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