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Pilot-scale catalytic ozonation pretreatment for improving the biodegradability of fixed-bed coal gasification wastewater

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PROCESS SAFETY AND ENVIRONMENTAL PROTECTION 2021年 148卷 13-19页

作者： chen, Xiaoya Wang, Chunrong Jiang, Longxin Li, Haiyan Wang, Jianbing He, xuwen China Univ Min & Technol Beijing Sch Chem & Environm Engn Beijing 100083 Peoples R China

Achieving zero liquid dischargeis a requirement for the development of the coal chemical industry;high pollutant concentration, strong biotoxicity, and poor biodegradability (BOD5/COD=0.1-0.2) make fixed-bed coal gasification wastewater difficult to treat. This study synthesized a Fe-Mn/lava catalyst (FMLC) and performed a pilot-scale test on catalytic ozonation for the pretreatment of fixed-bed coal gasification wastewater. The effects of ozone and catalyst dosages were investigated, and the changes in the organics, biotoxicity, and biodegradability of wastewater were analyzed using three-dimensional fluorescence spectroscopy, BOD5/COD, and specific oxygen uptake rate (SOUR). Energy consumption was also calculated. The removal efficiencies (at a flow rate of 1.0 m(3)/h, ozone dosage of 179 g/h, and catalyst dosage of 40 kg/m(3)) of COD and BOD5 were 61.77% and 16.98%, respectively, after 30 days of continuous operation. Toxic refractory macromolecular organic pollutants were transformed into small, biodegradable substances. BOD5/COD increased from 0.16 to 0.35, and SOUR decreased from 2.8460 to 2.3180 mgO(2)/(gMLSS.h). The operating cost was 1.24 kWh/kg COD. Catalytic ozonation as a pretreatment technology markedly improved biodegradability, reduced biotoxicity, and looks to be promising for treating fixed-bed coal gasification wastewater. (C) 2020 Published by Elsevier B.V. on behalf of Institution of Chemical Engineers.

关键词： Fixed-bed coal gasification wastewater Pilot-scale Catalytic ozonation Fe-Mn/lava catalyst Pretreatment Biodegradability

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Efficient removal and recovery of phosphorus from industrial wastewater in the form of vivianite

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ENVIRONMENTAL RESEARCH 2023年第1期228卷 115848页

作者： Zhang, Yangzhong Qin, Jiafu chen, Zhenguo chen, Yongxing Zheng, xuwen Guo, Lu Wang, Xiaojun South China Univ Technol Sch Environm & Energy Guangzhou 510006 Peoples R China South China Normal Univ Sch Environm Guangzhou 510006 Peoples R China Hua An Biotech Co Ltd Foshan 528300 Peoples R China

With the shortage of phosphorus resources, the concept of phosphorus recovery from wastewater is generally proposed. Recently, phosphorus recovery from wastewater in the form of vivianite has been widely reported, which could be used as a slow-release fertilizer as well as the production of lithium iron phosphate for Li-ion batteries. In this study, chemical precipitation thermodynamic modeling was applied to evaluate the effect of solution factors on vivianite crystallization with actual phosphorus containing industrial wastewater. The modeling results showed that the solution pH influences the concentration of diverse ions, and the initial Fe2+ concentration affects the formation area of vivianite. The saturation index (SI) of vivianite increased with the initial Fe2+ concentration and Fe:P molar ratio. pH 7.0, initial Fe2+ concentration 500 mg/L and Fe:P molar ratio 1.50 were the optimal conditions for phosphorus recovery. Mineral Liberation Analyzer (MLA) accurately determined the purity of vivianite was 24.13%, indicating the feasibility of recovering vivianite from industrial wastewater. In addition, the cost analysis showed that the cost of recovering phosphorus by the vivianite process was 0.925 USD/kg P, which can produce high-value vivianite products and realize "turn waste into treasure".

关键词： Phosphorus recovery Vivianite Crystallization zone Resource recycling

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负载姜黄素可注射微球延缓椎间盘的退变

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中国组织工程研究 2023年第12期27卷 1884-1891页

作者：叶旭文顾勇陈亮苏州大学附属第一医院江苏省苏州市215000

背景:椎间盘退变机制复杂,炎症通路激活、炎症因子泛滥、活性氧过度积累等均可加速椎间盘退变进程。姜黄素是从中药材姜黄中提取的天然药物,具有抑制炎症、抗氧化应激等药理作用。目的:探讨负载姜黄素的缓释微球局部注射延缓大鼠椎间盘... 详细信息

背景:椎间盘退变机制复杂,炎症通路激活、炎症因子泛滥、活性氧过度积累等均可加速椎间盘退变进程。姜黄素是从中药材姜黄中提取的天然药物,具有抑制炎症、抗氧化应激等药理作用。目的:探讨负载姜黄素的缓释微球局部注射延缓大鼠椎间盘退变的疗效。方法:①采用微流控技术制备负载姜黄素的甲基丙烯酸酰化明胶缓释微球,评估其体外释药和降解情况;②将缓释微球与未载药微球分别与髓核细胞共培养,以单独培养的细胞为对照,将3组细胞分别培养于正常环境和氧化应激环境(加入H_(2)O_(2))中,通过CCK-8、活/死染色实验评估细胞的活性与增殖情况,qRT-PCR实验检测相关因子的表达水平;③将30只SD大鼠随机分为正常组、退变组、未载药微球组、姜黄素组、缓释微球组,每组6只,在大鼠尾椎7-8和8-9节段经皮穿刺建立椎间盘退变模型,未载药微球组、姜黄素组、缓释微球组退变的椎间盘内注射对应的溶液。4周后,通过影像学与组织学观察椎间盘组织结构改变。结果与结论:①缓释微球可缓慢持续释放姜黄素,至28 d时释放姜黄素总量为(84.11±2.71)%;在含有胶原酶的PBS中,缓释微球质量逐渐减小,至第5周时消失。②CCK-8和活/死染色实验显示,在正常环境下,缓释微球不会影响髓核细胞的增殖活力;在氧化应激环境下,相比未载药微球,缓释微球可维持髓核细胞的增殖活力。qRT-PCR实验显示,相较于正常环境,氧化应激环境激活了髓核细胞中多种炎症因子mRNA的过量表达;在氧化应激环境下,相较于未载药微球组与对照组,缓释微球组肿瘤坏死因子α、白细胞介素1β、白细胞介素6及基质金属蛋白酶3的mRNA表达降低,Ⅱ型胶原和蛋白聚糖的mRNA表达升高。③动物体内实验结果显示,未载药微球组4周后的影像学与组织学评估与退变组比较无明显差异;姜黄素组的椎间隙高度及MRI评分在第1周时较退变组和未载药微球组虽有一定程度改善,但在第4周时其影像学与组织学评估均不如缓释微球组。④结果表明,姜黄素缓释微球能够抑制H_(2)O_(2)诱导的髓核细胞凋亡、延缓椎间盘退变进程,其机制与抑制核因子κB通路、降低氧化应激水平有关。

关键词：微流控技术纳米粒微球冷冻干燥姜黄素椎间盘退变甲基丙烯酸酐化明胶

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Design of a new scintillator-based fast ion loss detector on the HL-2A tokamak

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JOURNAL OF INSTRUMENTATION 2024年第10期19卷 P10013-P10013页

作者： Han, Yuxiao Xie, Jinlin Zhang, Jie He, Xiaofei Wang, Yongqing Liu, Linzi Xu, Hongbing Zhan, xuwen Liu, Kuancheng Zhang, Yipo Shi, Zhongbing chen, Wei Zhong, Wulv Xu, Min Zhuang, Gea Univ Sci & Technol China Dept Plasma Phys & Fus Engn Hefei Anhui Peoples R China Southwestern Inst Phys Chengdu Sichuan Peoples R China

A new scintillator-based fast ion loss detector (FILD) has been devised for the HL-2A tokamak, with the objective of discerning the temporal evolution of energy and pitch angle among lost fast ions. A code named FILD Simulation (FSC) has been developed to assist in the design of the detector head and the interpretation of experimental data. By optimising the geometric design, the resolutions of energy and pitch angle are optimised to 5 keV and 3 degrees, respectively. A branched imaging fiber bundle is used to relay the fluorescence image on the scintillator to two distinct instruments. One of these is a high-speed camera, while the other is a silicon photomultiplier tube (SiPM) array with a sampling rate of up to 1 MSamples/s. This configuration enables the attainment of superior temporal and spatial resolution, as well as high photon sensitivity.

关键词： Nuclear instruments and methods for hot plasma diagnostics Plasma diagnostics- high speed photography Plasma diagnostics- probes Scintillators, scintillation and light emission processes (solid, gas and liquid scintillators)

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水酶法提取毛叶山桐子油的工艺优化及其品质分析

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中国油脂 2024年第12期49卷 1-6页

作者：陈小静闻乐嫣向旭雯阚建全西南大学食品科学学院重庆400715 农业农村部农产品贮藏保鲜质量安全风险评估实验室重庆400715 中匈食品科学合作研究中心重庆400715

旨在为水酶法提取毛叶山桐子油的工业化应用提供参考,以毛叶山桐子鲜果为原料,通过单因素实验和响应面实验对水酶法提取毛叶山桐子油的工艺条件进行优化,并对水酶法提取的毛叶山桐子油与索氏抽提法、热榨法及低温压榨法提取的毛叶山桐... 详细信息

旨在为水酶法提取毛叶山桐子油的工业化应用提供参考,以毛叶山桐子鲜果为原料,通过单因素实验和响应面实验对水酶法提取毛叶山桐子油的工艺条件进行优化,并对水酶法提取的毛叶山桐子油与索氏抽提法、热榨法及低温压榨法提取的毛叶山桐子油品质进行比较。结果表明:水酶法提取毛叶山桐子油的最佳工艺条件为加热预处理(汽蒸10 min)、料液比1∶3.5、提取时间5.6 h、加酶量2.70%(酶为质量比1∶1的纤维素酶和中性蛋白酶),在此条件下毛叶山桐子油提取率达77.45%;与其他3种方法提取的毛叶山桐子油相比,水酶法提取的毛叶山桐子油酸值(KOH)(2.62 mg/g)和过氧化值(5.55 mmol/kg)最低,亚油酸含量最高(64.03%)。综上,优化的水酶法工艺提取的毛叶山桐子油品质较好。

关键词：水酶法毛叶山桐子鲜果油提取率油脂品质

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Study on the differences of low carbon development models for energy and power supply in different types of enterprise parks

Study on the differences of low carbon development models fo...

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Energy, Power and Electrical Technology (ICEPET), International Conference on

作者： xuwen Yan Weitao Hao Liping chen Wenxiu Wang Juntong Lu Guangzhou Power Supply Bureau of Guangdong Power Grid Co. Ltd Guangzhou Guangdong China Guangzhou Institute of Energy Conversion Chinese Academy of Sciences Guangzhou Guangdong China School of Mechanical and Power Engineering Shenyang University of Chemical Technology Shenyang Liaoning China School of Energy Science and Engineering University of Science and Technology of China Hefei Anhui China

ISBN: (数字)9798350352658

ISBN: (纸本)9798350352665

As the main entities of undertaking the intensive energy activities, the green and low-carbon development of the enterprise parks is one of the important means to achieve the "dual carbon" targets. Taking two different types of parks, an industrial park and a research and technology park, in Guangzhou as the research objects, using Homer software and taking the minimum total net present value as the objective function, this study carried out the capacity optimization for different scenarios in order to optimize the allocation and analysis of low-carbon energy and electricity development plans for the two different types of enterprise parks. The results showed that: (1) for enterprise parks, fully utilizing renewable energy and equipping energy storage systems could effectively improve the economic and low-carbon efficiency of the energy system, while making use of the excessive power with electricity to heat conversion technology did not have significant effect. (2) Due to the intensive nature of land use, the enterprise parks were unable to adopt renewable energy sources on a large scale, resulting in an increase of unit cost of power supply. Compared with the research and technology parks, the industrial parks still have potential to make further improvement in economic efficiency.

关键词： Renewable energy sources Power supplies Electricity Biological system modeling Wind power generation Software Resource management

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CircFBLN2 regulates duck myoblast proliferation and differentiation through miR-22-5p and MEF2C interaction

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POULTRY SCIENCE 2025年第5期104卷 105063页

作者： Liu, Shuibing Wu, Jintao Jiang, Hongxia Zhou, Ya'nan Huang, xuwen Wang, Yuxiang Xie, Zhanbin Liao, Zurong Ding, Zhenxvan Liu, Jing Hu, Xiaolong Mao, Huirong Liu, Sanfeng chen, Biao Jiangxi Agr Univ Coll Anim Sci & Technol Nanchang 330045 Jiangxi Peoples R China South China Agr Univ Coll Anim Sci Guangzhou 510642 Guangdong Peoples R China Jiangxi Agr Univ Poultry Inst Nanchang 330045 Peoples R China

The growth and development of duck skeletal muscle significantly affect duck meat production, making it essential to understand the molecular mechanisms underlying these processes. Circular RNAs (circRNAs) and microRNAs (miRNAs) are identified in many species and play essential roles in the regulation of myogenic processes;however, research on circRNAs and miRNAs involved in the duck skeletal muscle development is limited. In prior whole-transcriptome RNA sequencing study, we identified differential expression of miR-22-5p and the novel circular RNA circFBLN2, which arises from the second exon of the FBLN2 gene, in duck primary myoblasts (DPMs). In this study, we confirmed the circular structure of circFBLN2 and explored its expression patterns and functional implications in myogenesis. To elucidate the function of circFBLN2 in the myogenic processes of duck, we conducted experiments involving both the silencing and overexpression of circFBLN2 in DPMs. Our findings indicated that circFBLN2 inhibits DPM proliferation while promoting their differentiation. Conversely, when miR-22-5p was silenced and overexpressed, it exhibited opposing effects by promoting the proliferation of DPMs and inhibiting their differentiation. These results suggest a complex dynamic interplay between circFBLN2 and miR-22-5p in the regulation of DPMs proliferation and differentiation. Additionally, our results revealed that both circFBLN2 and myocyte enhancer factor 2 C (MEF2C) act as sponges for miR-22-5p, as demonstrated by binding predictions and dual-luciferase reporter assays. These results offer novel perspectives on the regulatory pathways underlying the duck embryonic skeletal muscle development, underscoring the pivotal function of circFBLN2 in the regulation of miR-22-5p expression. This research deepens our comprehension of the molecular underpinnings of avian myogenesis, potentially paving the way for more effective approaches to bolster growth and development of livestock.

关键词： Duck skeletal muscle circFBLN2 miR-22-5p MEF2C

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Stretchable, compressible, and conductive hydrogel for sensitive wearable soft sensors

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JOURNAL OF COLLOID AND INTERFACE SCIENCE 2022年 618卷 111-120页

作者： Peng, xuwen Wang, Wenda Yang, Wenshuai chen, Jingsi Peng, Qiongyao Wang, Tao Yang, Diling Wang, Jianmei Zhang, Hao Zeng, Hongbo Univ Alberta Dept Chem & Mat Engn Edmonton AB T6G 1H9 Canada Taiyuan Univ Sci & Technol Heavy Machinery Engn Res Ctr Educ Minist Taiyuan 030024 Peoples R China

Conductive hydrogels hold great promises in wearable soft electronics. However, the weak mechanical properties, low sensitivity and the absence of multifunctionalities (e.g., self-healing, self-adhesive, etc.) of the conventional conductive hydrogels limit their applications. Thus, developing multifunctional hydrogels may address some of these technical issues. In this work, a multifunctional conductive hydro gel strain sensor is fabricated by incorporating a conductive polymer Poly(3,4-ethylenedioxythiophene)poly(styrenesulfonate) (PEDOT: PSS) into a mechanically robust poly (vinyl alcohol) (PVA)/ poly (acrylic acid) (PAA) double network (DN) hydrogel. The as-prepared hydrogel sensor could span a wide spectrum of mechanical properties by simply tuning the polymer composition and the number of freezing-thawing cycles. In addition, the dynamic hydrogen bonding interactions endow the hydrogel sensor with self healing property and reversible adhesiveness on diverse substrates. Moreover, the hydrogel sensor shows high sensitivity (Gauge Factor from 2.21 to 3.82) and can precisely detect some subtle human motions (e.g., pulse and vocal cord vibration). This work provides useful insights into the development of conductive hydrogel-based wearable soft electronics.(c) 2022 Elsevier Inc. All rights reserved.

关键词： Conductive hydrogel Interfacial interaction Self-healing Soft hydrogel sensors

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Sex differences in externalizing and internalizing traits and ventral striatal responses to monetary loss

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JOURNAL OF PSYCHIATRIC RESEARCH 2023年第1期162卷 11-20页

作者： Li, Guangfei Li, Yashuang Zhang, Zhao chen, Yu Li, Bao Hao, Dongmei Yang, Lin Yang, Yimin Li, xuwen Li, Chiang-Shan R. Beijing Univ Technol Fac Environm & Life Dept Biomed Engn Beijing Peoples R China Beijing Int Sci & Technol Cooperat Base Intelligen Beijing Peoples R China Beijing Inst Technol Sch Life Sci Dept Biomed Engn Beijing Peoples R China Yale Univ Sch Med Dept Psychiat New Haven CT USA Yale Univ Sch Med Dept Neurosci New Haven CT USA Yale Univ Sch Med Interdept Neurosci Program New Haven CT USA Yale Univ Wu Tsai Inst New Haven CT USA Beijing Univ Technol 220 Life Sci Bldg 100 Pingleyuan Beijing 100124 Peoples R China Connecticut Mental Hlth Ctr S112 34 Pk St New Haven CT 06519 USA

Ventral striatum (VS) processes rewarding and punishing stimuli. Women and men vary in externalizing and internalizing traits, which may influence neural responses to reward and punishment. To investigate sex dif-ferences in how individual traits influence VS responses to reward and punishment, we curated the data of the Human Connectome Project and identified 981 (473 men) subjects evaluated by the Achenbach Adult Self-Report Syndrome Scales. We processed the imaging data with published routines and extracted VS response (beta) to win and to loss vs. baseline in a gambling task for correlation with externalizing and internalizing symptom severity. Men vs. women showed more severe externalizing symptoms and higher VS response to monetary losses (VS-loss beta) but not to wins. Men but not women showed a significant, positive correlation between VS-loss beta and externalizing traits, and the sex difference was confirmed by a slope test. The correlations of VS-loss vs. exter-nalizing and of VS-win vs. externalizing and those of VS-loss vs. externalizing and of VS-loss vs. internalizing traits both differed significantly in slope, confirming its specificity, in men. Further, the sex-specific relationship between VS-loss beta and externalizing trait did not extend to activities during exposure to negative emotion in the face matching task. To conclude, VS responses to loss but not to win and their correlation with externalizing rather than internalizing symptom severity showed sex differences in young adults. The findings highlight the relationship of externalizing traits and VS response to monetary loss and may have implications for psychological models of externalizing behaviors in men.

关键词： Externalizing VS Punishment Sex differences fMRI

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Functional differentiation analysis of duplicated mlpha gene in Oujiang color common carp (Cyprinus carpio var. color) on colour formation

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AQUACULTURE RESEARCH 2021年第10期52卷 4565-4573页

作者： Hu, xuwen chen, Honglin Yu, Luwei chen, Xiaowen Mandal, Biplab Kumar Wang, Jun Wang, chenghui Shanghai Ocean Univ Natl Demonstrat Ctr Expt Fisheries Sci Educ Key Lab Freshwater Aquat Genet Resources Shanghai Engn Res Ctr AquacultureMinist Agr & Ru Shanghai Peoples R China Zhejiang Acad Agr Sci Inst Hydrobiol Hangzhou Peoples R China

Melanophilin (mlph) encodes a subfamily of Rab effector proteins which is an important gene for the transportation of mature melanosomes. Duplicated mlpha gene (mlpha1 and mlpha2) of Oujiang color common carp (Cyprinus carpio var. color) was firstly identified in the present study, which includes an open reading frame (ORF) length of 1713 bp and 1536 bp, encoding 570 and 511 amino acids respectively. Spatial and temporal expression, in situ hybridization and disruption experiments were conducted to explore the functional differentiation of mlpha (mlpha1 and mlpha2) during the melanin transport process of Oujiang color common carp. Distinct expression pattern of mlpha1 and mlpha2 were identified, and the expression level of mlpha1 in red skin of whole red with black patch (RB-R) and white skin of whole white with black patch (WB-W) was significantly lower than their corresponding black skin of RB and WB (RB-B and WB-B). On the contrary, the expression level of mlpha2 in RB-R and WB-W was significantly higher than their corresponding black skin (RB-B and WB-B). Mlpha2 was highly expressed in the "Whole red" (WR) skin, and mlpha1 was lowly expressed in the WR. Meanwhile, abundant positive ISH hybridization signals of mlpha2 were identified in 5 days post-hatch larvae (5dph) of WR. The high mutation rate of mlpha1 and mlpha2 genes resulted in a significant dilution phenotype, while the low mutation rate led to partial skin to appear discoloration phenomenon of Oujiang color common carp (RB and WB). The findings indicated that mlpha is an indispensable functional gene that may participate in the transportation of pigments and functional differentiation may exist between mlpha1 and mlpha2 after duplication. Mlpha1 may be mainly involved in the transportation of melanin, and mlpha2 may also participate in the transportation of other pigments.

关键词： CRISPR Cas9 functional differentiation melanophilin melanosomes Oujiang color common carp

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