The neutron capture reaction cross sections of U-238 were measured at the neutron energies of 14.1, 14.5 and 14.8 MeV using the activation method and off-line gamma-ray spectrometric technique. The induced gamma-ray a...
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The neutron capture reaction cross sections of U-238 were measured at the neutron energies of 14.1, 14.5 and 14.8 MeV using the activation method and off-line gamma-ray spectrometric technique. The induced gamma-ray activities were measured using a low background gamma ray spectrometer equipped with a high resolution HPGe detector. The excitation functions of the U-238(n, gamma)U-239 reaction were also calculated theoretically using the TALYS-1.8 program and are in general agreement with experimental data. The experimentally determined cross sections were compared with the data in the literature, and the evaluated data of ENDF/B-VIII.0, JENDL-4.0, and CENDL-3.1, as well as calculated results from TALYS-1.8.
Process-in-Memory (PIM) has become a favorable solution for data intensive applications with its advantages of placing processing units in or near memory, reducing the movement of data between memory and processing un...
Process-in-Memory (PIM) has become a favorable solution for data intensive applications with its advantages of placing processing units in or near memory, reducing the movement of data between memory and processing unit. However, most recent PIM platforms have relatively large limitations in terms of computing flexibility and types of computing, and programming is complicated, which cannot provide a unified programming framework. Therefore, it becomes a challenge to deploy the code to the hardware, which severely restricts the application development on the PIM platform. This paper presents a method of code conversion based on the PIM platform, which allows users to develop applications on the PIM platform with the high-level programming language, makes the PIM platform more accessible in the development of data intensive applications.
The A1 subunit of cholera toxin (CTA1) retains the adjuvant function of CT, without its toxic side effects, making the molecule a promising mucosal adjuvant. However, the methods required to obtain a pure product are ...
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The A1 subunit of cholera toxin (CTA1) retains the adjuvant function of CT, without its toxic side effects, making the molecule a promising mucosal adjuvant. However, the methods required to obtain a pure product are both complicated and expensive, constricting its potential commercial applicability. Here, we fused the peptidoglycan binding domain (PA) to the C-terminus of CTA1, which enabled the fusion protein to be expressed by Bacillus subtilis, and secreted into the culture medium. CTA1 was then purified and displayed on GEM particles using a one step process, which resulted in the formation of CTA1-GEM complexes. Next, the CTA1-GEM complexes were used as an adjuvant to enhance the immune responses of mice to the influenza subunit vaccine. It was observed that the CTA1-GEM complexes enhanced specific systemic (IgG) and mucosal (IgA) immune responses against antigen, and induced cellular immune responses as well. The data presented here suggests that CTA1-GEM complexes can serve as a viable mucosal adjuvant. (C) 2017 Elsevier Inc. All rights reserved.
Coverage-guided fuzzing is a widely used and effective solution to find software vulnerabilities. Tracking code coverage and utilizing it to guide fuzzing are crucial to coverage-guided fuzzers. However, tracking full...
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ISBN:
(纸本)9781538643532
Coverage-guided fuzzing is a widely used and effective solution to find software vulnerabilities. Tracking code coverage and utilizing it to guide fuzzing are crucial to coverage-guided fuzzers. However, tracking full and accurate path coverage is infeasible in practice due to the high instrumentation overhead. Popular fuzzers (e.g., AFL) often use coarse coverage information, e.g., edge hit counts stored in a compact bitmap, to achieve highly efficient greybox testing. Such inaccuracy and incompleteness in coverage introduce serious limitations to fuzzers. First, it causes path collisions, which prevent fuzzers from discovering potential paths that lead to new crashes. More importantly, it prevents fuzzers from making wise decisions on fuzzing strategies. In this paper, we propose a coverage sensitive fuzzing solution CollAFL. It mitigates path collisions by providing more accurate coverage information, while still preserving low instrumentation overhead. It also utilizes the coverage information to apply three new fuzzing strategies, promoting the speed of discovering new paths and vulnerabilities. We implemented a prototype of CollAFL based on the popular fuzzer AFL and evaluated it on 24 popular applications. The results showed that path collisions are common, i.e., up to 75% of edges could collide with others in some applications, and CollAFL could reduce the edge collision ratio to nearly zero. Moreover, armed with the three fuzzing strategies, CollAFL outperforms AFL in terms of both code coverage and vulnerability discovery. On average, CollAFL covered 20% more program paths, found 320% more unique crashes and 260% more bugs than AFL in 200 hours. In total, CollAFL found 157 new security bugs with 95 new CVEs assigned.
The world’s first 1.3 GHz cryomodule containing eight 9-cell superconducting radio-frequency (rf) cavities treated by medium-temperature furnace baking (mid-T bake) was developed at the Institute of High Energy Physi...
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The world’s first 1.3 GHz cryomodule containing eight 9-cell superconducting radio-frequency (rf) cavities treated by medium-temperature furnace baking (mid-T bake) was developed at the Institute of High Energy Physics, Chinese Academy of Sciences. The 9-cell cavities in the cryomodule achieved an unprecedented high average intrinsic quality factor (Q0) of 3.8×1010 at 16 MV/m and 3.6×1010 at 21 MV/m in the horizontal test. The cryomodule can operate stably up to a total continuous wave rf voltage greater than 193 MV, with an average cavity usable accelerating gradient of more than 23 MV/m. The results significantly exceed the specifications of Circular Electron Positron Collider and Dalian advanced light source and the other high repetition rate free electron laser facilities [Linac Coherent Light Source II (LCLS-II), LCLS-II-high energy, Shanghai High Repetition Rate X-ray FEL and Extreme Light Facility, Shenzhen Superconducting Soft X-Ray Free Electron Laser, etc.]. There is evidence that the mid-T bake cavity may not require fast cooldown or long processing time in the cryomodule. This paper reviews the cryomodule performance and discusses some important issues in cryomodule assembly and testing.
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