Favorable facility layouts could effectively improve production efficiency, reduce production cost, and improve comprehensive competitiveness. Take the inefficient workshop facility layout of the H Company as an examp...
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Favorable facility layouts could effectively improve production efficiency, reduce production cost, and improve comprehensive competitiveness. Take the inefficient workshop facility layout of the H Company as an example, the paper studies both transportation and processing cycle for raw materials of its main products, records statistically transport distances and transport weights for each raw material in each processing workshop, and discovers principal issues in the transportation and processing cycle for the H Company. This paper adopts the Systematic Layout Planning(SLP) approach to optimize the layout design of the H Company, and compares non-optimized layout scheme with optimized one from qualitative and quantitative analysis aspect by using the analytic hierarchy process approach. The results show that the application of SLP approach in the H Company could enhance obviously the performance of its workshop facility layout.
Rheumatoid arthritis(RA)is a chronic autoimmune disorder characterized by persistent joint inflammation leading to bone and cartilage damage and even ***,the pathogenesis of RA is multi-factorial and to a large degree...
Rheumatoid arthritis(RA)is a chronic autoimmune disorder characterized by persistent joint inflammation leading to bone and cartilage damage and even ***,the pathogenesis of RA is multi-factorial and to a large degree,remains *** Sini decoction(DSD),a traditional Chinese medicine(TCM)formula,has been widely used as a remedy for rheumatoid arthritis(RA)in recent *** our study,1H-nuclear magnetic resonance(1H-NMR)based metabolomics analysis of 7 potential biomarkers,including taurine(1),urea(2),betaine(3),pyruvate(4),hippurate(5),succinate(6)and acetone(7)was performed to investigate the progression of RA and assess the efficacy of DSD in collagen-induced arthritis(CIA)*** to pathway analysis using identified metabolites and correlation construction,taurine and hypotaurine metabolism,gut microbiota metabolism,pyruvate metabolism,glycolysis/gluconeogenesis,the citrate cycle(TCA cycle)and lipid metabolism were recognized as being the most influenced metabolic pathways associated with *** a result,deviations of metabolites 1,3,4,5,6 and 7 in CIA rats were improved by DSD,which suggested that DSD mediated the abnormal metabolic pathways *** summary,the efficacy and its underlying therapeutic mechanisms of DSD on RA were systematically investigated and expect to provide a new insight in relevant studies of other TCM formulas.
We report a case of mycotic keratitis caused by Bipolaris oryzae with predisposing trauma from a foreign body. The fungus was identified by sequencing the internal transcribed spacer region, translation elongation fac...
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We report a case of mycotic keratitis caused by Bipolaris oryzae with predisposing trauma from a foreign body. The fungus was identified by sequencing the internal transcribed spacer region, translation elongation factor 1 alpha (TEFL) gene, and partial glyceraldehyde-3-phosphate dehydrogenase (GPDH) gene, and the species identity was confirmed on the basis of its characteristic conidial phenotype. The patient was treated with surgical intervention and antifungal agents, including intravenous fluconazole (FLC), oral itraconazole, topical 0.15% amphotericin B eye drops, and 0.5% FLC eye drops. To our knowledge, this is the first report of mycotic keratitis caused by B. oryzae worldwide. (C) 2016 Elsevier Inc. All rights reserved.
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