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INDIVIDUAliZED SPORTS MANAGEMENT SCHEME FOR PREGNANT WOMEN IN CHINA

JOURNAL OF MECHANICS IN MEDICINE AND BIOLOGY 2019年第8期19卷

作者： Yang, lin Luo, Qi Lu, Yang Zhang, Song Yang, Yimin li, xuwen Hao, Dongmei Xu, Mingzhou Shao, Jing Beijing Univ Technol Coll Life Sci & Bioengn Beijing 100124 Peoples R China Beijing Elect Power Hosp Beijing 100073 Peoples R China Beijing Aerosp Chang Feng Co Ltd Beijing 100071 Peoples R China Beijing Yes Med Devices Co Ltd Beijing 100152 Peoples R China

In recent years, pregnant women in China generally face problems such as unbalanced and excessive nutrition, lack of proper exercise during pregnancy, which shows a significant increase in weight during pregnancy, leading to an increasing trend of perinatal complications. At present, there is less sports health management system for pregnant women throughout pregnancy. In view of this, based on the existing research in related fields, this study deeply explores the appropriate monitoring methods of pregnant women's sports in China. In this study, effective and convenient testing methods and evaluation criteria were proposed for pregnant women's sports and psychology. The research idea was a method based on the pulse wave to detect pregnant women's cardiac reserve capacity, and grading the Diastolic/Systolic value of pregnant women as a reference for grading individualized target heart rate range of moderate intensity exercise. The effective time and energy expenditure of pregnant women were assessed by monitoring the exercise process. The purpose is to help and guide pregnant women in the whole process of pregnancy self-movement management, and thus improve the quality of maternal health care services in China.

关键词： Pregnancy health sports management pulse wave, exercise assessment

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Comparing Electrochemical Passivation and Surface Film Chemistry of 654SMO Stainless Steel and C276 Alloy in Simulated Flue Gas Desulfurization Condensates

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MATERIALS 2024年第8期17卷 1827页

作者： liao, Luhai Cheng, Yifan Zhang, He Yuan, xuwen li, Fengguang Wuhan Univ Sci & Technol Key Lab Ferrous Met & Resources Utilizat Minist Educ Wuhan 430081 Peoples R China Wuhan Univ Sci & Technol Hubei Prov Key Lab New Proc Ironmaking & Steel Mak Wuhan 430081 Peoples R China Hubei Univ Automot Technol Sch Mat Sci & Engn Shiyan 442002 Peoples R China

This research examines the behavior of electrochemical passivation and the chemistry of surface films on 654SMO super austenitic stainless steel and C276 nickel-based alloy in simulated condensates from flue gas desulfurization in power plant chimneys. The findings indicate that the resistance to polarization of the protective film on both materials initially rises and then falls with either time spent in the solution or the potential of anodic polarization. Comparatively, 654SMO exhibits greater polarization resistance than C276, indicating its potential suitability as a chimney lining material. Mott-Schottky analysis demonstrates that the density of donors in the passive film formed on 654SMO exceeds that on C276, potentially due to the abundance of Fe oxide in the passive film, which exhibits the characteristics of an n-type semiconductor. The primary components of the passive films on both materials are Fe oxides and Cr oxides. The formation of a thin passive film on C276 in the simulated condensates is a result of the low Gibbs free energy of nickel oxide and low Cr content. The slower diffusion coefficient of point defects leads to the development of a thicker and more compact passive film on the surface of 654SMO.

关键词： super austenitic stainless steel nickel-based alloy electrochemical passivation behavior flue gas desulfurization passive film

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水包砂多彩涂料的制备及应用

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涂料工业 2020年第4期50卷 70-75,87页

作者：包媛李旭文徐萍传化智联股份有限公司杭州311215 中海油常州涂料化工研究院有限公司江苏常州213016

介绍了水包砂多彩涂料的制备工艺流程,对保护胶的用量和种类、纤维素醚用量和种类、不同类型的乳液、防沉剂的种类进行平行实验。实验结果表明:选用S482为保护胶,涂料的耐水白性和稳定性好;分散相中疏水改性纤维素醚HE-10K用量为0.4%~0... 详细信息

介绍了水包砂多彩涂料的制备工艺流程,对保护胶的用量和种类、纤维素醚用量和种类、不同类型的乳液、防沉剂的种类进行平行实验。实验结果表明:选用S482为保护胶,涂料的耐水白性和稳定性好;分散相中疏水改性纤维素醚HE-10K用量为0.4%~0.6%、250HBR用量为0.2%~0.6%,连续相中4%S-482保护胶溶液用量为25%、HY-1黄原胶用量为0.025%、TX-100乳液用量为3%~5%、RS-3799乳液用量为12%~15%时,所制的水包砂多彩涂料具有强度适中、抗渗色性强、耐水白性好、贮存稳定性好的特点。

关键词：水包砂多彩涂料耐水白保护胶疏水改性纤维素醚

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Optimizing Carbon Dioxide Injection for Methane Hydrate Development and Carbon Sequestration: A Long-Term Numerical Simulation Study

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ENERGY & FUELS 2024年第21期38卷 20629-20643页

作者： Zhang, Zhaobin li, Yuxuan Xu, Tao li, Shouding li, Xiao Lu, Cheng Qin, xuwen Chinese Acad Sci Key Lab Shale Gas & Geoengn Inst Geol & Geophys Beijing 100029 Peoples R China Chinese Acad Sci Inst Earth Sci Beijing 100049 Peoples R China Univ Chinese Acad Sci Coll Earth & Planetary Sci Beijing 100049 Peoples R China Minist Nat Resources China Geol Survey Oil & Gas Resources Survey Beijing 100083 Peoples R China Natl Engn Res Ctr Gas Hydrate Explorat & Dev Guangdong 510075 Peoples R China China Geol Survey China Aero Geophys Survey & Remote Sensing Ctr Nat Beijing 100083 Peoples R China

Although in theory, carbon dioxide replacement for methane hydrate development can simultaneously enhance methane production rates and achieve carbon sequestration, its feasibility under field conditions has not been thoroughly investigated. This study proposes a carbon dioxide injection and methane development replacement strategy using a multiwell injection and production system. A custom-developed hydrate simulator was used to model the replacement process and its long-term evolution over 100,000 years. The results indicate that for shallowly buried hydrate reservoirs in seafloor sediments, carbon dioxide injection can significantly enhance methane production rates. The resulting carbon dioxide hydrates remain stable after the reservoir temperature and pressure recover, which facilitating carbon sequestration. Analysis of reservoir conditions reveals that carbon dioxide replacement is less effective for deeply buried methane hydrate reservoirs. Additionally, shallower water depths and intact seal integrity are favorable for carbon dioxide replacement. To achieve optimal replacement, the carbon dioxide injection rate must be carefully controlled;both excessive injection rates and premature injection can lead to carbon dioxide breakthrough from the injection well to the production well. Overall, this study provides insights into the feasibility analysis, site selection, and operational optimization for carbon dioxide replacement in methane hydrate development and carbon sequestration.

关键词： Carbon sequestration

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Understanding the Mechanisms of Texture Evolution of a Fe-24Cr-22Ni-7Mo Super Austenitic Stainless Steel During cold Rolling and Annealing

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METALS AND MATERIALS INTERNATIONAL 2024年第10期30卷 2777-2790页

作者： liao, Luhai Dai, Shang Guo, Rui Yuan, xuwen li, Fengguang Hubei Univ Automot Technol Sch Mat Sci & Engn Shiyan 442002 Peoples R China Hubei Univ Automot Technol Key Lab Automot Power Train & Elect Shiyan 442002 Peoples R China Univ Sci & Technol Beijing Sch Mat Sci & Engn Beijing 100083 Peoples R China

In present study, the texture evolution during cold rolling and subsequent annealing of a Fe-24Cr-22Ni-7Mo super austenitic stainless steel was investigated, and new insights into the mechanisms of texture evolution were obtained. The results show that macrotexture evolution during cold rolling can be categorized into two stages. Below 33.3% cold reduction, the material form strong Goss, Copper, and S texture component due to dislocation plane slipping. Above 33.3% reduction, strong Brass, Goss, and Copper-Twin texture components are formed, accompanied by a decrease in Copper and S component content. Moreover, when the cold reduction reaches 66.6%, the strength of the gamma-fibre texture suddenly increases. This increase is attributed to the rotation of the Copper-oriented grains and the Copper-Twin-oriented grains in the lamellar twin region to {111}<1line>21line>> and {111}<21line>1line>> along < 011>//TD direction, respectively. It is significant to note that twinning plays a dominant role in the formation of the Brass-type texture in the super austenitic stainless steel at large deformation. Additionally, the annealing of cold deformed materials results in the formation of random and scattered recrystallization texture. This may be due to the small difference in deformation energy storage of grains with different orientations after austenite deformation.

关键词： Super austenitic stainless steel Texture Microstructure Rolling Annealing

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CUG-STCN: A seabed topography classification framework based on knowledge graph-guided vision mamba network

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INTERNATIONAL JOURNAL OF APPliED EARTH OBSERVATION AND GEOINFORMATION 2025年 136卷

作者： Wang, Haoyi Chen, Weitao li, Xianju liang, Qianyong Qin, xuwen li, Jun China Univ Geosci Fac Comp Sci Wuhan 430074 Peoples R China China Univ Geosci Key Lab Geol Survey & Evaluat Minist Educ Wuhan 430074 Peoples R China China Geol Survey Guangzhou Marine Geol Survey Guangzhou 511400 Peoples R China China Geol Survey China Aero Geophys Survey & Remote Sensing Ctr Nat Beijing 100083 Peoples R China

Multibeam sounding is a high-precision remote sensing method for seabed detection. Seabed topography classification is crucial for marine science research, resource exploration and engineering. When using multibeam data for seabed topography automatic classification, the fuzzy boundaries of different topographic entities, redundancy of multimodal data, and the lack of geological knowledge guidance have led to low classification accuracy. Thus, a knowledge graph-guided vision mamba seabed topography classification network (CUG-STCN) was constructed, consisting of three modules: (1) The long sequence modeling mamba-based encoder addresses the fuzzy seabed topography boundary. It uses 2D-selective-scan to create image blocks in different scanning directions. By combining with the selective state space model to capture long-range dependencies and ensure transmission of spatial context information while maintaining linear computational complexity. (2) The crossmodal information interaction and fusion module addresses the redundancy of multimodal information. By employing a bidirectional information interaction mechanism, it captures the correlations of seabed topography between different modalities and achieving feature fusion. (3) The seabed topography knowledge graph-guided semantic perception module guides the geological knowledge. It constructs seabed topography knowledge vectors through entity query and word embedding, using the similarity between vectors to create a similarity measurement matrix. It provides geological knowledge, enhancing the modeling capability of complex seabed topography relationship. CUG-STCN achieves OA of 90.11% and mIOU of 48.50%, outperforming six mainstream networks, which at most, achieve the OA and mIOU improvements of 5.37% and 14.18%. Notably, the application of CUG-STCN in other regions demonstrates its strong generalization performance.

关键词： Multibeam Seabed topography Mamba Knowledge graph Remote sensing

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Disrupting Tumor Lactate Homeostasis to Sensitize Chemo-Immunotherapy Using a Glucose-Disguised Lactate Interceptor

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ACS nano 2025年第23期19卷 2025 Jun 5页

作者： xuwen li Shuo Geng Qinjun Chen Boyu Su Haolin Song Jingyi Zhou Ru Jia Hongrui Fan Chufeng li Yu Wang Zonghua Tian Tao Sun Chen Jiang Department of Pharmaceutics School of Pharmacy Fudan University Shanghai 201203 China. Key Laboratory of Smart Drug Delivery Ministry of Education Fudan University Shanghai 201203 China. State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science Fudan University Shanghai 201203 China. Department of Digestive Diseases National Regional Medical Center Binhai Campus of the First Affiliated Hospital Fujian Medical University Fuzhou 350212 China.

Aberrantly elevated lactate flux in tumors is increasingly recognized as a key driver of metabolic symbiosis, immunosuppression, and, ultimately, immunogenic chemotherapy resistance. Here, we propose a precise lactate homeostasis modulation strategy that selectively intercepts intracellular lactate molecules in highly glycolytic tumor cells. Targeting monocarboxylate transporter 4 (MCT4), a key lactate efflux transporter overexpressed in tumor cells, we developed a glucose-disguised delivery system for precise transport of regulatory molecules into glycolysis-dependent tumor cells. By modulating lactate-mediated crosstalk between heterogeneous tumor subpopulations (glycolysis-dependent and lactate-consuming cells) and immune cells, this strategy effectively disrupts lactate-driven metabolic cooperation within the tumor niche, which may contribute to overcoming lactate-associated resistance to chemo-immunotherapy.

关键词： chemo-immunotherapy sensitization immune activation lactate metabolic regulation metabolic symbiosis tumor microenvironment

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Optimization of the natural gas hydrate hot water injection production method: Insights from numerical and phase equilibrium analysis

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APPliED ENERGY 2024年 361卷

作者： Zhang, Zhaobin li, Yuxuan li, Shouding He, Jianming li, Xiao Xu, Tao Lu, Cheng Qin, xuwen Chinese Acad Sci Key Lab Shale Gas & Geoengn Inst Geol & Geophys Beijing 100029 Peoples R China Chinese Acad Sci Innovat Acad Earth Sci Beijing 100029 Peoples R China Univ Chinese Acad Sci Coll Earth & Planetary Sci Beijing 100049 Peoples R China Minist Nat Resources China Geol Survey Oil & Gas Resources Survey Beijing 100083 Peoples R China Minist Nat Resources China Geol Survey Guangzhou Marine Geol Survey Guangzhou 510075 Peoples R China

The heat injection during depressurization is a crucial technique for sustaining the long-term gas production rate of natural gas hydrate. To analyze the production patterns and mechanisms of hydrate dissociation under various heat injection conditions and to further optimize heat injection strategies, this study establishes a reservoir-scale three-dimensional heterogeneous computational model using a self-developed hydrate simulator. A novel in-situ heating method utilizing bottom seawater is proposed for heat injection, and comprehensive analyses of heating power and injection rates are conducted. The results indicate that increasing heating power at a constant injection rate enhances gas production rates while reducing thermal efficiency. Simultaneously, under constant heating power, gas production rates initially increase and then decrease with increasing injection rates, revealing the presence of an optimal injection rate. This paper introduces the concepts of temperature driving force and temperature modification ratio, analyzes the mechanisms of heat injection development, and derives an optimized strategy for hot water injection through curve fitting. This research enhances our understanding of the integrated approach involving thermal stimulation and depressurization, providing significant guidance for future production endeavors.

关键词： Natural gas hydrate Thermal stimulation Three-dimensional modelling Temperature driving force Comprehensive analysis

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The impact of radiotherapy on the prognosis of metastatic clear cell renal cell carcinoma after surgery

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Scientific Reports 2025年第1期15卷 1-11页

作者： li, xuwen Tan, Zhongyu Zhu, Yihao Zhai, Yabo Chen, Can Wang, Dong Wang, Mingshuai Xing, Nianzeng Yang, Feiya Ye, Xiongjun Department of Urology National Cancer Center National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China First Clinical Medical College Nanchang University Nanchang China Zunyi Medical University Zunyi China

Clear cell renal cell carcinoma, one of the most common types of renal cell carcinoma, has been increasing in incidence year by year. This study aims to investigate the impact of radiotherapy on the prognosis of patients with metastatic clear cell renal cell carcinoma (mccRCC) undergoing cytoreductive surgery. Clinical data of patients with mccRCC who underwent cytoreductive surgery were collected from the SEER database (2000–2021). This study employed propensity score matching (PSM) and R software to evaluate the overall survival (OS) of radiotherapy. Univariate and multivariate COX regression analyses were conducted to explore the impact of different variables on prognosis. Finally, a nomogram was developed to predict patient survival rates. A total of 2076 patients with mccRCC who underwent cytoreductive surgery were included in this study, with 538 (25.92%) in the radiotherapy group and 1539 (74.08%) in the non-radiotherapy group. After propensity score matching (PSM), there were 300 cases in each group. Kaplan-Meier values and the Cox proportional hazards model were used to plot the overall survival (OS) curves, which showed that the median survival time in the radiotherapy group was significantly lower than that in the non-radiotherapy group. Additionally, multivariate Cox regression analysis revealed that tumor grade, N stage, radiotherapy, lung metastasis, and liver metastasis were independent factors affecting the prognosis of patients with mccRCC undergoing cytoreductive surgery. Lastly, a nomogram was developed to estimate the survival rates of patients with mccRCC after cytoreductive surgery. Radiotherapy after cytoreductive surgery may have an adverse impact on the prognosis of patients with mccRCC. © The Author(s) 2025.

关键词： Metastatic clear cell renal cell carcinoma Overall survival Propensity score matching Radiotherapy Surgery

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薤中新的甾体皂苷类化学成分

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高等学校化学学报 2021年第6期42卷 1742-1753页

作者：杨依然姚华闫江红孙志恒张余房雪晴李绪文金永日吉林大学化学学院长春130012 吉林大学中日联谊医院长春130033 吉林省中医药科学院第一临床医院长春130021 新南威尔士大学材料科学学院悉尼2033澳大利亚

从薤(Allium chinense ***)的乙醇提取物中分离得到6个新甾体皂苷类化合物,通过波谱数据及理化性质分析,鉴定其分别为5α-cholano-22,16-内酯-3-O-β-D-吡喃葡萄糖基-(1→2)-[β-D-吡喃葡萄糖基-(1→3)]-β-D-吡喃葡萄糖基(1→4)-β-D-... 详细信息

从薤(Allium chinense ***)的乙醇提取物中分离得到6个新甾体皂苷类化合物,通过波谱数据及理化性质分析,鉴定其分别为5α-cholano-22,16-内酯-3-O-β-D-吡喃葡萄糖基-(1→2)-[β-D-吡喃葡萄糖基-(1→3)]-β-D-吡喃葡萄糖基(1→4)-β-D-吡喃半乳糖苷(1)、6-酮-5α-cholano-22,16-内酯-3-O-β-D-吡喃木糖基-(1→4)-[α-L-吡喃阿拉伯糖基-(1→6)]-β-D-吡喃葡萄糖苷(2)、(25R)-26-O-β-D-吡喃葡萄糖基-5α-呋喃甾烷-3β,26-二醇-3-O-β-D-吡喃葡萄糖基-(1→2)-[β-D-吡喃葡萄糖基-(1→3)]-β-D-吡喃葡萄糖基(1→4)-β-D-吡喃半乳糖苷(3)、(25R)-6-酮-26-O-β-D-吡喃葡萄糖基-5α-呋喃甾烷-3β,22α,26-三醇-3-O-α-L-吡喃木糖基-(1→4)-β-D-吡喃葡萄糖苷(4)、(25R)-6-酮-5α-呋喃甾烷-3β,22α,24β,26-四醇-3-O-β-D-吡喃木糖基-(1→4)-[α-L-吡喃阿拉伯糖基-(1→6)]-β-D-吡喃葡萄糖苷(5)和(25R)-5α-呋甾-2α,3β,22α,26-四醇-26-O-β-D-吡喃葡萄糖苷(6).化合物1和2的皂苷元骨架在天然产物中首次分离得到.选用H_(2)O_(2)诱导PC12细胞神经氧化损伤模型,初步考察了6种新的呋甾型化合物的抗氧化活性,实验结果表明,化合物3对由H_(2)O_(2)诱导的细胞氧化损伤有显著的保护效果.

关键词：薤呋甾皂苷结构鉴定细胞活性抗氧化能力

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