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湖泊科学 2022年第4期34卷 1384-1391页

作者：宋挺张军毅李旭文朱家民胡俊江苏省无锡环境监测中心无锡214121 江苏省环境监测中心南京210008 上海市青浦区环境监测站上海201799

随着全球气候变化和水体富营养化,在过去几十年中蓝藻水华改变了全球的淡水生态系统.蓝藻因独有的藻蓝蛋白而大多呈现蓝绿色,因此其水华也常称为蓝绿藻水华.然而随着蓝藻水华关注度的不断提升,尤其是监测和研究的不断深入,经常在水体中... 详细信息

随着全球气候变化和水体富营养化,在过去几十年中蓝藻水华改变了全球的淡水生态系统.蓝藻因独有的藻蓝蛋白而大多呈现蓝绿色,因此其水华也常称为蓝绿藻水华.然而随着蓝藻水华关注度的不断提升,尤其是监测和研究的不断深入,经常在水体中发现蓝藻水华出现黄化的现象.例如,太湖出现的黄色蓝藻水华,冬春季以长孢藻属(Dolichospermum)水华为主,夏秋季以微囊藻属(Microcystis)水华为主.即使外观看起来是蓝绿色的蓝藻水华,但仔细观察形成蓝藻水华的群体颗粒,也有部分呈现黄色,反之亦然.实际上,鉴于色素组成的差异性,也许水体中就没有两个颜色完全一致的蓝藻群体颗粒.目前对于黄色的蓝藻水华及其形成机理,国内外鲜有报道和研究.光照和氮限制被认为是最有可能的原因.在关注蓝藻水华黄化的同时,更应该关注和研究这些颜色变化给蓝藻水华及水环境所带来的风险和挑战,尤其是对水生态管理工作的启发和意义.

关键词：蓝藻水华黄色叶绿素类胡萝卜素藻胆蛋白

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The Pararectus approach in acetabular fractures treatment: functional and radiologcial results

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BMC MUSCULOSKELETAL DISORDERS 2022年第1期23卷 370-370页

作者： liu, Guoming Chen, Jinli liang, Chengzhi Zhang, Chengdong li, xuwen Hu, Yanling Qingdao Univ Dept Orthoped Affiliated Hosp Qingdao 266003 Shandong Peoples R China

Background The surgical treatment of complex acetabular fractures is one of the most challenging procedures for orthopedic surgeons. The Pararectus approach, as a reasonable alternative to the existing surgical procedures, was performed for the treatment of acetabular fractures involving the anterior column. This study aimed to evaluate outcome using the Pararectus approach for acetabular fractures involving anterior columns. Methods Thirty-seven with displaced acetabular fractures involving anterior columns were treated between July 2016 and October 2019 using the Pararectus approach. The functional outcomes (using the Merle d Aubigne and Postel scoring system, WOMAC and modified Harris scoring), the quality of surgical reduction (using the Matta criteria), and postoperative complications were assessed during approximately 26 months follow-up period. Results Thirty-seven patients (mean age 53 years, range: 30-71;28 male) underwent surgery. Mean intraoperative blood loss was 840 ml (rang: 400-2000 ml) and mean operating time was 210 min (rang: 140-500 min). The modified Merle d Aubigne score was excellent and good in 27 cases (73%), fair in 6 cases (16%), and poor in 3 cases (11%). The mean score was 88.5 (range:77-96) for the modified Harris Hip scores, and 22 (range:7-35) for the WOMAC scores after operation. Postoperative functional outcomes were significantly improved compared with preoperative outcomes (P < 0.0001). The quality of reduction was anatomical in 21 cases (57%), satisfactory in 9 cases (24%), and unsatisfactory in 7 cases (19%). At follow-up, four patients developed a DVT, and heterotopic bone formation was observed in one patient. The hip osteoarthritis was not observed. Conclusion The Pararectus approach achieved good functional outcomes and anatomical reduction in the treatment of acetabular fractures involving anterior column with minimal access morbidity.

关键词： Acetabular fracture Pararectus approach Surgical exposure Outcome Radiological results

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Exploring the mechanism of sweetener neohesperidin dihydrochalcone on oral tolerance via a network pharmacology approach combined with vivo and vitro methods

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JOURNAL OF FUNCTIONAL FOODS 2022年第0期95卷

作者： Shi, Xiaolei Wei, Jihao Zhang, Yupu Xue, Jingwen Jin, Yongri li, xuwen Jilin Univ Coll Food Sci & Engn Changchun Peoples R China Jilin Univ Coll Chem Changchun Peoples R China JilinState Tobacco Monopoly Adm Changchun Peoples R China Jilin Univ Coll Chem 2699 Qianjin Rd Changchun 130012 Peoples R China

Neohesperidin dihydrochalcone (NHDC) is a kind of sweetener widely used in food processing. Some artificial sweeteners induce food allergy by breaking oral tolerance (OT). The relationship between NHDC and oral tolerance are important in food safety. We explored the possible effects of NHDC on OT via network pharmacology combined with vivo and vitro experiments. NHDC was predicted to have effects on OT. It was focus on immunoglobulin production, inflammation and immunity. Then, OT mouse model and mast cell degranulation were applied to further explore the mechanism. NHDC could affect the Th2 response by suppressing the sIgG1 level in the serum and GATA-3 expression in the colon. NHDC could inhibit RBL-2H3 cells degranulation by suppressing the Ca2+ influx and MAPK signaling pathways. Results showed that NHDC can be safely applied in food processing and had promotional effects on oral tolerance.

关键词： Sweetener Tolerance Food allergy Risk Mechanism Food safety

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The complete chloroplast genome of the lipstick tree,Bixa Orellana(Bixaceae)

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Mitochondrial DNA Part B 2019年第1期4卷 17-18页

作者： Seping Dai xuwen li Jianzhong Ni lin Ruan Renchao Zhou Wei Lun Ng Guangzhou Institute of Forestry and Landscape Architecture Guangzhou China State Key Laboratory of Biocontrol and Guangdong Provincial Key Laboratory of Plant Resources School of Life Science Sun Yat-sen University Guangzhou China

Bixa orellanais a small tree known for its red, oil-soluble pigment contained in the seed coat that is used as a natural dye and food coloring. In this study, we assembled and characterized the complete chloroplast genome ofB. orellanaas a resource for future genetic studies. With a total length of 159,825 bp, the chloroplast genome comprised of a large single-copy (LSC) region of 89,476 bp, a small single-copy (SSC) region of 19,617 bp, and two inverted repeat (IR) regions of 25,356 bp each. A total of 127 genes were predicted, consisting of 83 protein-coding genes, 36 tRNA genes, and 8 rRNA genes. Phylogenetic analysis confirmed the position ofB. orellanawithin the order Malvales.

关键词： Bixa achiote natural dye complete chloroplast genome automated assembly

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Single-Atom Fe-Anchored Nano-Diamond With Enhanced Dual-Enzyme Mimicking Performance for H2O2 and Glutathione Detection

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FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY 2022年 9卷 790849页

作者： liu, Ying Yan, Jianghong Huang, Yu Sun, Zhiheng Zhang, Huijing Fu, lihaoyuan li, xuwen Jin, Yongri Jilin Univ Coll Chem Changchun Peoples R China First Clin Hosp Jilin Prov Acad Tradit Chinese Med Changchun Peoples R China

Glutathione (GSH) is an important antioxidant and free radical scavenger that converts harmful toxins into harmless substances and excretes them out of the body. In the present study, we successfully prepared single-atom iron oxide-nanoparticle (Fe-NP)-modified nanodiamonds (NDs) named Fe-NDs via a one-pot in situ reduction method. This nanozyme functionally mimics two major enzymes, namely, peroxidase and oxidase. Accordingly, a colorimetric sensing platform was designed to detect hydrogen peroxide (H2O2) and GSH. Owing to their peroxidase-like activity, Fe-NDs can oxidize colorless 3,3 ',5,5 '-tetramethylbenzidine (TMB) into blue with sufficient linearity at H2O2 concentrations of 1-60 mu M and with a detection limit of 0.3 mu M. Furthermore, using different concentrations of GSH, oxidized TMB can be reduced to TMB, and the color change from blue to nearly colorless can be observed by the naked eye (linear range, 1-25 mu M;detection limit, 0.072 mu M). The established colorimetric method based on oxidase-like activity can be successfully used to detect reduced GSH in tablets and injections with good selectivity and high sensitivity. The results of this study exhibited reliable consistency with the detection results obtained using high-performance liquid chromatography (HPLC). Therefore, the Fe-NDs colorimetric sensor designed in this study offers adequate accuracy and sensitivity.

关键词： nanodiamond single-atom Fe peroxidase-like and oxidase-like activity colorimetric sensor glutathione

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No ureteral catheter mini percutaneous nephrolithotomy (NUC-mPCNL) achieves enhanced recovery after surgery (ERAS)

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SCIENTIFIC REPORTS 2024年第1期14卷 1-7页

作者： li, xuwen Tan, Zhongyu Yu, Yue Zhou, Xiaochen Xi, Haibo liu, Wei Nanchang Univ Affiliated Hosp 1 Dept Urol Jiangxi Prov Key Lab Urinary Syst DisJiangxi Med Nanchang Jiangxi Peoples R China

Conventional mini percutaneous nephrolithotomy (mPCNL) typically necessitates the pre-operative placement of ureteral catheters. With the development of enhanced recovery after surgery (ERAS), we introduce a novel approach: no ureteral catheter mini percutaneous nephrolithotomy (NUC-mPCNL). To evaluate the efficacy and safety of this innovative procedure compared to mPCNL, we compared the total operative time, stone clearance rate (SCR), stone-free rate (SFR), and complications among patients undergoing either modality from January to September 2021. Our findings revealed a statistically significant reduction in the mean total operative time for the NUC-mPCNL group (42.6 +/- 2.4 vs. 60.2 +/- 3.4 min, p < 0.001). The SCR, SFR and CSFR were comparable between two groups (98.5% vs. 97.8%, 84.3% vs. 76.0%, 64.7% vs. 60.0%, p = 0.337, 0.295, 0.625). WBC rise, hemoglobin drop and neutrophil percentage rise were similar in both groups. The overall complication rate in the NUC-mPCNL group was lower;however, the difference was not statistically significant (Clavien I, II and III;11 vs. 13, 1 vs. 2 and 1 vs. 1). Consequently, we conclude that NUC-mPCNL effectively shortens the operative time and holds potential for expedited postoperative recovery.

关键词： Renal stones Enhanced recovery after surgery Mini percutaneous nephrolithotomy Ureteral catheter Efficacy

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水包砂多彩涂料的制备及应用

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涂料工业 2020年第4期50卷 70-75,87页

作者：包媛李旭文徐萍传化智联股份有限公司杭州311215 中海油常州涂料化工研究院有限公司江苏常州213016

介绍了水包砂多彩涂料的制备工艺流程,对保护胶的用量和种类、纤维素醚用量和种类、不同类型的乳液、防沉剂的种类进行平行实验。实验结果表明:选用S482为保护胶,涂料的耐水白性和稳定性好;分散相中疏水改性纤维素醚HE-10K用量为0.4%~0... 详细信息

介绍了水包砂多彩涂料的制备工艺流程,对保护胶的用量和种类、纤维素醚用量和种类、不同类型的乳液、防沉剂的种类进行平行实验。实验结果表明:选用S482为保护胶,涂料的耐水白性和稳定性好;分散相中疏水改性纤维素醚HE-10K用量为0.4%~0.6%、250HBR用量为0.2%~0.6%,连续相中4%S-482保护胶溶液用量为25%、HY-1黄原胶用量为0.025%、TX-100乳液用量为3%~5%、RS-3799乳液用量为12%~15%时,所制的水包砂多彩涂料具有强度适中、抗渗色性强、耐水白性好、贮存稳定性好的特点。

关键词：水包砂多彩涂料耐水白保护胶疏水改性纤维素醚

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The Pulse Waveform and Parameters Analysis of Various Athletes Based on Radial Pulse

The Pulse Waveform and Parameters Analysis of Various Athlet...

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IEEE Workshop on Electronics, Computer and Applications

作者： Anran Wang xuwen li lin Yang Xingxing Yang Lanxi Meng Jun Su Song Zhang College of Life Science and Bio-engineering Beijing University of Technology 100124 China|c|

ISBN: (纸本)9781479945641

Classify the sports events by the maximal oxygen uptake (MaxO_2) and the maximal muscular voluntary contraction (MVC). Collect the radial pulse wave of different sports events and discuss the pulse waveform and characteristic parameters. Radial pulse waveform on 304 subjects was collected, by using PowerLab and its bundled software LabChart 7,developed by ADInstrument. Normalize each radial pulse waveform and let the waveform cycle and amplitude distribute in the range of 0-100. Analyze the relative time of the maximum point Tm, the abscissa X and ordinate Y of dicrotic notch, the pulse waveform area K and the pulse wave age index SDPTG. The pulse waveform changing trend of MVC (<50%) group and MVC (>50%) group are different while the sports have the same Max02. And the pulse waveform changing trend of MaxO_2 (<40%) group, MaxO_2 (40%-70%) group and MaxO_2 (>70%) group are as well as different while the sports have the same MVC.

关键词： Athlete Pulse wave Radial artery Waveform parameter

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Study of Pulse Wave Changes in Patients with End-stage Renal Disease Receiving Hemodialysis Treatment 23

Study of Pulse Wave Changes in Patients with End-stage Renal...

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Proceedings of the 2023 4th International Symposium on Artificial Intelligence for Medicine Science

作者： Ziwei li Chong Wang lin Yang Jie Yang Ying li Cuiting lian Dongmei Hao Guangfei li Yimin Yang xuwen li Faculty of Chemistry and Life Sciences Beijing University of Technology China Beijing Jishuitan Hospital Capital Medical University China

ISBN: (纸本)9798400708138

This study presents a novel experimental approach to investigate the changes in pulse wave patterns and pulse wave characteristic parameters in patients before, during, and after hemodialysis by analyzing radial artery pulse waves collected at time intervals from end-stage renal disease patients receiving hemodialysis. The results show that the morphology of the pulse wave is characterized by diversity between patients due to different vascular elasticity, but five categories can be classified according to the shape. When individuals of the same waveform Type-Are studied, we found that there were significant differences in some of the characteristic parameters of the pulse wave at different times of the day as the hemodialysis process progressed, a finding that also verifies the existence of hemodynamic changes during hemodialysis.

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Nomogram to screen older adult patients attending the radiology department for sarcopenia

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BMC GERIATRICS 2025年第1期25卷 1-9页

作者： Yuan, Guiying Ye, Guoxi Hu, Jianguang Hu, Huimin Shi, Chanmei Zhang, Ye Huang, Junbing li, Zhiqiong Zeng, xuwen Tan, Rongshao Xiong, Yuchao Jinan Univ Guangzhou Red Cross Hosp Dept Resp Guangzhou Peoples R China Jinan Univ Guangzhou Red Cross Hosp Dept Radiol 396 Tongfu Rd Guangzhou Guangzhou 510220 Guangdong Provi Peoples R China Jinan Univ Guangzhou Red Cross Hosp Dept Nephrol Guangzhou Peoples R China Jinan Univ Guangzhou Red Cross Hosp Inst Dis Oriented Nutr Res Dept Clin Nutr Guangzhou Peoples R China

BackgroundSarcopenia is an age-related syndrome that can impact the physical and mental health of older adults. However, it is often overlooked in clinical practice. Therefore, we aim to construct a nomogram based on simplified discriminant parameters for screening older adult patients for sarcopenia *** cross-sectional study included 654 patients aged >= 60 years who underwent an examination in the radiology department between October 2023 and June 2024. Patients were diagnosed with sarcopenia according to the method and cutoff value criteria proposed the Asian Working Group on Sarcopenia (AWGS) 2019 criteria. Calf circumference (CC), SARC-F score, mid-upper arm circumference (MUAC), and SARC-CalF score were used as simplified discriminant parameters for sarcopenia. The discriminative ability of these parameters for sarcopenia was assessed using receiver operating characteristic analysis. Additionally, we included each screening parameter and evaluated it's important for screening for the presence of sarcopenia via univariate and multivariate logistic regression analysis to develop a new screening nomogram model. The performance of the nomogram was evaluated using receiver operating characteristic curves, and the performance of the nomogram model was compared to that of CC, SARC-F, MUAC, and the SARC-CalF using the Delong *** the 654 subjects, 120 (18.3%) were diagnosed with sarcopenia, and the areas under the curve (AUCs) of the CC, SARC-F, MUAC, and SARC-CalF were 0.73, 0.61, 0.66, and 0.70, respectively. The multivariate analysis results revealed that older age, male sex, low CC, low MUAC, and low strength were related to sarcopenia. A nomogram model constructed with these five variables had an AUC of 0.84. The DeLong test showed that the diagnostic efficacy of the joint model was significantly higher than that of CC, SARC-F, MUAC, and *** simple nomogram based on simplified discriminant parameters offers personalized

关键词： Sarcopenia Nomogram Calf circumference SARC-F SARC-CalF

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