检索结果-内蒙古大学图书馆

Boosting catalytic performance of N doped porous carbon derived from coal tar pitch: The role of N species and the contribution of 1O2

引用

JOURNAL OF WATER PROCESS ENGINEERING 2025年 72卷

作者： Huang, Linlin Zhang, xuwen Wang, Lin Liu, Tingting Li, Da Sheng, Tao sun, Caiyu Li, Lixin Heilongjiang Univ Sci & Technol Coll Environm & Chem Engn Harbin 150022 Peoples R China Harbin Inst Technol State Key Lab Urban Water Resource & Environm Harbin 150090 Peoples R China

In this study, nitrogen-doped carbon material (N-PC-d) derived from coal tar pitch using dicyandiamide as N source was successfully synthesized, exhibiting outstanding catalytic performance in the activation of peroxymonosulfate (PMS) for the degradation of Orange G (OG). By optimizing key parameters such as PMS dosage, NPC dosage, nitrogen source, pH, anions, and PS source, the optimal N-PC-d/PMS system achieved a degradation rate 1.45 times higher than that of the PC/PMS system within a broad pH range (2.0-10.0). Through electron paramagnetic resonance (EPR) and quenching experiments, it was found that singlet oxygen (1O2) was the predominant species accountable for OG degradation, while reactive oxygen species (ROS), including superoxide (O2 & sdot;-), hydroxyl radicals (& sdot;OH), and sulfate radicals (SO4 & sdot;-), played auxiliary roles. Moreover, the structure-activity relationship analysis revealed that functional groups such as C--C, C--O, and pyridine N were mainly involved in PMS activation. The degradation mechanism of OG was further elucidated by high-performance liquid chromatography-mass spectrometry (HPLC-MS). This research presented a cost-efficient N-doped porous carbon material for environmental remediation and provides more profound insights into the mechanisms of PMS activation by N doped carbon-based materials.

关键词： N-doped porous carbon Coal tar pitch PMS Singlet oxygen Orange G

来源：评论

学校读者我要写书评

暂无评论

Preparation and properties of ceramic coated nitrogen-doped carbon coated SiOx anode materials for lithium-ion batteries

引用

APPLIED PHYSICS A-MATERIALS SCIENCE & PROCESSING 2025年第5期131卷 1-7页

作者： Zhou, Zhengyang Wen, Lijun Jin, Chenxin Hong, Junjie Liu, xuwen Xu, Guojun sun, Fugen Li, Yong Zhou, Lang Yue, Zhihao Nanchang Univ Inst Photovolta Nanchang 330031 Peoples R China Jiangxi Prov Key Lab Solar Photovolta Nanchang 330031 Peoples R China NCU GQC Inst PV HE ES Technol Gongqing 332020 Peoples R China Nanchang Univ Sch Phys & Mat Sci Nanchang 330031 Peoples R China

Nitrogen doping and carbon coating were identified to be two effective ways to alleviate the problems of silicon raw materials in our previous work. Building upon the foundation of this, a ceramic coating technique is introduced to further enhance the physical and electrochemical characteristics of nitrogen-doped carbon-coated silicon monoxide (N-doped SiOx@C) materials. This study explores the application of alumina (Al2O3) and boehmite (AlOOH) powders as coating on the surface of N-doped SiOx@C materials to assess their effects. The outcomes demonstrate that AlOOH coating surpasses Al2O3 coating in terms of wettability and liquid absorption capacity, leading to a reduction in the contact angle from 28 degrees to 20 degrees. Following 100 cycles at a current density of 1.05 Ag-1, the capacity retention rate of AlOOH coated N-doped SiOx@C materials reaches 98.4%, whereas uncoated materials maintain a capacity retention rate of 91.4%. Notably, AlOOH coating significantly enhances the electrochemical performance of N-doped SiOx@C materials.

关键词： Ceramic coating Surface modification Silicon oxide materials Lithium ion batteries

来源：评论

学校读者我要写书评

暂无评论

Identification of DDX5 as a Potential Therapeutic Target of Osteosarcoma Using Thiazolone Probes

引用

ACS CHEMICAL BIOLOGY 2024年第8期19卷 1803-1812页

作者： sun, Donghui Kang, Li Chen, xuwen Xue, Jian Wu, Xin Wong, Jiemin Wei, Qinghua Liu, Shunying East China Normal Univ Shanghai Engn Res Ctr Mol Therapeut & New Drug Dev Sch Chem & Mol Engn Shanghai 200062 Peoples R China East China Normal Univ Fengxian Dist Cent Hosp Inst Biomed SciECNU Joint Ctr Translat Med Shanghai Key Lab Regulatory Biol Shanghai Peoples R China East China Normal Univ Sch Life Sci Shanghai 200241 Peoples R China

Osteosarcoma (OS) is a rare malignant tumor that has predominantly affected children and adolescents in the past 50 years. The genomes of OS tumors exhibit a high degree of complexity, which leads to the great challenge of target identification for anti-OS. To date, no efficient therapeutic target for the treatment of OS has been validated in clinical practice. In our previous drug hunting for the treatment of OS by phenotypic screening, we found that thiazolone derivate (R)-8i was an effective and selective inhibitor against OS in MNNG/HOS cells and in vivo. However, the mechanism of action and specific molecular targets of (R)-8i remain unclear. In this study, we design and synthesize the photo-cross-linking probes based on the lead compound (R)-8i and identify DDX5 as a potential target protein using an activity-based protein profiling strategy. Further experiments including Western blot, shRNA knockdown experiments, cell colony formation, wound healing assays, and cellular thermal shift assays support that (R)-8i binds to DDX5 and induces its degradation, which affect cell proliferation and migration through the PI3K-AKT-mTOR signaling pathway. The research shows that DDX5 is a potential therapeutic target for the treatment of OS.

关键词：

来源：评论

学校读者我要写书评

暂无评论

Metal-Organic Frameworks-Derived Cobalt Catalyst Supported on Biochar for Efficient Deoxygenation of Stearic Acid

引用

INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH 2025年第4期64卷 2049-2060页

作者： Zhang, xuwen Dong, Xuexue Wang, Youting Bian, Juanjuan Ali, Sajid Cai, Dongren sun, Kang Rao, Xiaoping Jiang, Jianchun Zhan, Guowu Huaqiao Univ Acad Adv Carbon Convers Technol Coll Chem Engn Xiamen 361021 Fujian Peoples R China Huaqiao Univ Fujian Prov Key Lab Biomass Low Carbon Convers Xiamen 361021 Fujian Peoples R China Chinese Acad Forestry CAF Inst Chem Ind Forest Prod Nanjing 210042 Jiangsu Peoples R China

The conversion of stearic acid into linear hydrocarbons is a crucial step in advancing sustainable biofuels and biochemicals. Herein, we developed a series of cobalt-based catalysts (referred to as Co/C@TSC) using metal-organic frameworks (MOFs) as precursors and supporting them on biochar derived from natural tung shells (TSC). Tung shells, a byproduct of the tung oil extraction process, are widely available. The as-designed Co/C@TSC catalyst effectively deoxygenated stearic acid via decarbonylation/decarboxylation (DCO x ) processes, achieving a conversion of 78.5% and hydrocarbon product selectivity of 90%, specifically heptadecane and heptadecene. Our detailed analysis showed that the addition of biochar support improved the spatial distribution of cobalt species (with a high surface concentration of Co0) and enhanced the adsorption of reactants, thus boosting catalytic activity. Additionally, in situ DRIFTS analysis confirmed that the stearic acid deoxygenation process involved the intermolecular dehydration of stearic acid molecules. Experiments with different reaction substrates revealed that the stearic anhydride was a key reaction intermediate during the deoxygenation process. This study introduces a novel catalyst made from dual carbon-supported nonprecious metals, presenting a promising method for transforming stearic acid into valuable hydrocarbon products.

关键词： Reaction intermediates

来源：评论

学校读者我要写书评

暂无评论

An ultrastable sodium-ion battery anode enabled by carbon-coated porous NaTi2(PO4)3 olive-like nanospheres

引用

JOURNAL OF COLLOID AND INTERFACE SCIENCE 2023年第1期635卷 417-426页

作者： Man, Yuehua sun, Jianlu Zhao, xuwen Duan, Liping Fei, Yating Bao, Jianchun Mo, Xiangyin Zhou, Xiaosi Nanjing Normal Univ Sch Chem & Mat Sci Nanjing 210023 Peoples R China City Univ Hong Kong Dept Mat Sci & Engn Kowloon Hong Kong 999077 Peoples R China

NaTi2(PO4)3 (NTP) is a promising anode material for sodium-ion batteries (SIBs). It has drawn wide atten-tion because of its stable three-dimensional NASICON-type structure, proper redox potential, and large accommodation space for Na'. However, the inherent low electronic conductivity of the phosphate framework reduces its charge transfer kinetics, thus limiting its exploitation. Therefore, this paper pro-poses a material with carbon-coated porous NTP olive-like nanospheres (p-NTP@C) to tackle the issues above. Based on experimental data and theoretical calculations, the porous structure of the material is found to be able to provide more active sites and shorten the Na' diffusion distance. In addition, the car-bon coating can effectively improve the electron and Na' diffusion kinetics. As the anode material for SIBs, the p-NTP@C olive-like nanospheres exhibit a high reversible capacity (127.3 mAh g-1 at 0.1 C) and ultrastable cycling performance (84.8% capacity retention after 10,000 cycles at 5 C). Furthermore, the sodium-ion full cells, composed of p-NTP@C anode and Na3V2(PO4)2F3@carbon cathode, also deliver excellent performance (75.7% capacity retention after 1000 cycles at 1 C). In brief, this nanostructure design provides a viable approach for the future development of long-life and highly stable NASICON-type anode materials.(c) 2022 Elsevier Inc. All rights reserved.

关键词： NaTi2(PO4)3 Porous structure Carbon coating Anode Sodium-ion battery

来源：评论

学校读者我要写书评

暂无评论

U75V钢轨轨头核伤原因分析

引用

高速铁路新材料 2024年第6期3卷 63-67页

作者：孙旭文张倩史启帅王雪娜铁科金化检测中心有限公司北京100081 中国铁道科学研究院集团有限公司金属及化学研究所北京100081

将核伤U75V钢轨伤损处打开,采用宏观形貌观察、断口微观形貌观察、金相组织观察、材料理化性能检测等手段,综合分析其核伤产生原因。结果表明:该钢轨的伤损类型为起源于轨头内部的纵横裂型核伤;导致钢轨产生纵横裂核伤的主要原因为轨距... 详细信息

将核伤U75V钢轨伤损处打开,采用宏观形貌观察、断口微观形貌观察、金相组织观察、材料理化性能检测等手段,综合分析其核伤产生原因。结果表明:该钢轨的伤损类型为起源于轨头内部的纵横裂型核伤;导致钢轨产生纵横裂核伤的主要原因为轨距角轮轨接触应力影响区内,存在沿钢轨轧制方向分布的粗大非金属夹杂物,在轮轨接触应力和动弯应力作用下,疲劳裂纹以非金属夹杂物为源开始萌生并先沿纵向后转为横向扩展。通过提高钢轨的纯净度,加强冶金质量的控制和检验,减少和细化钢中非金属夹杂物的数量和尺寸,可以有效减少此类纵横裂型核伤的产生。同时通过适当改善现有的常规探伤检测方式,增加纵向裂纹检测手段,可以在核伤形成的早期发现并及时处理。

关键词： U75V钢轨纵横裂型核伤疲劳裂纹非金属夹杂物

来源：评论

学校读者我要写书评

暂无评论

Identification of maize seed vigor under different accelerated aging times using hyperspectral imaging and spectral deep features

引用

COMPUTERS AND ELECTRONICS IN AGRICULTURE 2025年 231卷

作者： Zhu, Hongfei Yang, Ranbing Lu, Miaomiao Shi, Weiming sun, Wenbin Lv, Danyang Liu, Hang Wu, Qiong Jiang, xuwen Han, Zhongzhi Hainan Univ Haikou 570100 Peoples R China Qingdao Agr Univ Qingdao 266109 Peoples R China Minist Agr & Rural Affairs Key Lab Trop Intelligent Agr Equipment Sanya 572025 Peoples R China

Maize seed vigor plays a crucial role in improving crop yield. This study proposes a novel method for detecting maize seed vigor via the MAC-seq2seq model. The model successfully reconstructs the spectral sequence of maize seeds. After optimization and iteration, the model achieved a root mean square error (RMSE) of 2.818 x 10-6 on the test set. Subsequently, deep spectral features were extracted using the pretrained MAC-seq2seq, and an ensemble learning model was applied to detect the seed aging hours, with an accuracy of 93.33 %. Additionally, by labeling the spectral sequences with seed vigor index, the combination of ensemble learning and deep spectral features achieved a detection accuracy of 97.62 % for seed vigor. Ultimately, an online seed vigor detection platform was constructed, which effectively measures seed aging time and vigor, was constructed. This study provides an efficient strategy for the nondestructive detection of maize seed vigor, significantly enhancing detection accuracy.

关键词： Maize Seed Vigor Spectral Reconstruction Deep Features Ensemble Learning

来源：评论

学校读者我要写书评

暂无评论

Size and Charge Dual-Switchable Nanoparticles for Achieving Chemosensitization and Immune Infiltration against Pancreatic Ductal Adenocarcinoma

引用

ADVANCED FUNCTIONAL MATERIALS 2025年第1期35卷

作者： Song, Haolin Chen, Hongyi Chen, Qinjun Fan, Hongrui Li, Chufeng Wang, Yu Zhang, Shilin Li, xuwen Su, Boyu sun, Tao Jiang, Chen Fudan Univ Sch Pharm Dept Pharmaceut Key Lab Smart Drug DeliveryMinist EducState Key Shanghai 201203 Peoples R China MOE Frontiers Ctr Brain Sci Shanghai 201203 Peoples R China Fujian Med Univ Affiliated Hosp 1 Natl Reg Med Ctr Dept Digest Dis Binhai Campus Fuzhou 350212 Peoples R China

Pancreatic ductal adenocarcinoma (PDAC), one of the most challenging cancers, is uniquely characterized by a biological barrier composed of multiple components in the extracellular matrix, preventing penetration of chemotherapeutic agents and hindering clinical drug treatment. Collagen I arrangement is critical. In this study, gemcitabine is chosen as the chemotherapeutic agent and dasatinib as the collagen-I-disrupting agent. When collagen I arrangement is disrupted, not only the chemotherapeutic drug enters the tumor area better, but the infiltration of CD8+ T cells into the tumor also increases. Therefore, a hypoxia-responsive linker-crosslinked polymer, DGD/L@GBI, is designed, which can be simultaneously loaded with two therapeutic agents, gemcitabine and dasatinib. The polymer is encapsulated by nucleic acid aptamers that target the PDAC stromal microenvironment and shield the surface. The aptamer is removed upon arrival at the PDAC hypoxic microenvironment, exposing the positively charged core to achieve charge reversal. Particle size transformation is achieved using linkers that respond to a hypoxic microenvironment. Increased intratumoral penetration is achieved using the dual transformation capabilities of the formulation. Pairing these two agents can result in a powerful efficacy in chemotherapy sensitization and immune infiltration.

关键词： charge reversal chemosensitization immune infiltration pancreatic ductal adenocarcinoma size reduction

来源：评论

学校读者我要写书评

暂无评论

Discovery of Chalcone Derivatives as Bifunctional Molecules with Anti-SARS-CoV-2 and Anti-inflammatory Activities

引用

JOURNAL OF NATURAL PRODUCTS 2024年第12期87卷 2680-2694页

作者： Chen, xuwen Li, Hongtao Wang, Meiting sun, Donghui Lu, Jiani Zhu, Tong Chen, Hongzhuan Chen, Lili Liu, Shunying East China Normal Univ Shanghai Engn Res Ctr Mol Therapeut & New Drug Dev Sch Chem & Mol Engn Shanghai 200062 Peoples R China Shanghai Univ Tradit Chinese Med Inst Interdisciplinary Integrat Med Res Shanghai Frontiers Sci Ctr TCM Chem Biol Longhua Hosp Shanghai 201203 Peoples R China Shanghai Univ Tradit Chinese Med Shanghai Inst Infect Dis & Biosecur Inst Interdisciplinary Integrat Med Res Shanghai Frontiers Sci Ctr TCM Chem Biol Shanghai 201203 Peoples R China

Danshensu extracted with traditional Chinese medicine Salvia miltiorrhiza has a wide range of bioactivities. Danshensu containing a catechol moiety has a moderate inhibitory effect on SARS-CoV-2 3CLpro (IC50 = 2.2 mu M) by a reversible covalent interaction and exhibits good anti-inflammatory activity. To enhance the inhibitory activity, we introduced Michael receptors into the side chain of danshensu as a possible covalent warhead and blocked the covalent binding sites of catechol moiety to yield chalcone derivatives. The resulting chalcone derivatives, A4 and A7, were found to inhibit SARS-CoV-2 3CLpro in vitro with IC50 values of 83.2 and 261.3 nM, respectively. Furthermore, A4 and A7 inhibit viral replication in the SARS-CoV-2 replicon system with EC50 values of 19.9 and 11.7 mu M, respectively. Time-dependent inhibition experiment and mass spectrometry show that A4 acted as a noncovalent mixed inhibitor, while A7 likely binds covalently at Cys145. The interaction mechanism between SARS-CoV-2 3CLpro and A4 or A7 was characterized by molecular docking studies. Additionally, both A4 and A7 demonstrated potent anti-inflammatory activity in lipopolysaccharide (LPS)-stimulated RAW264.7 macrophage cells. These promising results suggest that chalcone derivatives A4 and A7 can serve as bifunctional molecules with both antivirus and anti-inflammatory properties.

关键词：

来源：评论

学校读者我要写书评

暂无评论

A universal strategy for fast,scalable,and aqueous synthesis of multicomponent palladium alloy ultrathin nanowires

引用

Science China Chemistry 2021年第2期64卷 245-252页

作者： Hao Lv xuwen Guo Lizhi sun Dongdong Xu Ben Liu College of Chemistry Sichuan UniversityChengdu 610064China Jiangsu Key Laboratory of New Power Batteries Jiangsu Collaborative Innovation Center of Biomedical Functional MaterialsSchool of Chemistry and Materials ScienceNanjing Normal UniversityNanjing 210023China

Noble metal alloy nanowires(NWs)with ultrathin diameters(2–3 nm)and precisely controllable elemental compositions have attracted dramatically growing attention for(electro)*** numerous achievements in past two decades,noble metal alloy NWs are mostly synthesized with the traditional oil-phase methods that suffer from some undesirable ***,we report a general strategy for fast,scalable,and aqueous synthesis of multicomponent Pd-based alloy ultrathin NWs with an average diameter of 2.6 nm,ranging from bimetallic PdM(PdFe,PdCo,PdNi,PdCu,PdZn,PdRu,PdRh,PdAg,PdCd,PdIr,PdPt,PdAu)and binary PdS/PdP NWs,to trimetallic PdM1M2 NWs(PdAuCu,PdCoNi,PdCuZn,PdCuNi,PdAgCu,PdAuCu,PdRuAg,PdAuRu,and PdPtAu),and to tetrametallic PdM1M2M3 NWs(PdAuAgCu,PdCoCuNi,PdAuCuNi,PdPtAuCu,and PdIrPtAu).The key to the success of this aqueous synthesis is the utilization of N2H4 as the extremely strong reducing agent that directs the synchronous reduction and anisotropic nucleation growth of multicomponent Pd alloy NWs along nanoconfined columnar phase assembled with amphiphilic dioctadecyldimethylammonium ***-resultant Pd-based alloy ultrathin NWs exhibit multiple structural and compositional synergies,which remarkably optimize the removal of poisoning ethoxy intermediates and thus improve electrocatalytic performance towards ethanol oxidation reaction(EOR).Among them,tetrametallic PdAuCuNi alloy ultrathin NWs hold a high EOR activity of 5.14 A mg-1 Pd and a low activation energy of 13.1 kJ mol^-1,both of which are much better than its counterpart catalysts alloyed with less *** work represents an important advance in precise aqueous synthesis of multicomponent noble metal alloy ultrathin NWs as the high-performance electrocatalysts for various targeted applications.

关键词： ultrathin nanowires multicomponent alloys palladium synthetic chemistry ethanol oxidation reaction

来源：评论

学校读者我要写书评

暂无评论

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案：

请选择收藏分类：

通借通还

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：