检索结果-内蒙古大学图书馆

C^1;1-RECTIFIABILITY AND HEINTZE-KARCHER INEQUALITY ON Sⁿ⁺¹

ESAIM-CONTROL OPTIMISATION AND CALCULUS OF VARIATIONS 2023年 29卷

作者： zhang, xuwen Xiamen Univ Sch Math Sci Xiamen 361005 Peoples R China Goethe Univ Inst Math D-60325 Frankfurt Germany

In this paper, by isometrically embedding (Sn+1, gS(n+1)) into Rn+2, and using nonlinear analysis on the codimension-2 graphs, we will show that the level-sets of the distance function from the boundary of any open se... 详细信息

关键词： Level-sets of distance function C-1 1 -rectifiability Heintze-Harcher-type inequality

来源：评论

学校读者我要写书评

暂无评论

Side-Chain-Functionalized Poly(indacenodithiophene-alt-benzothiadizole)s as Stretchable High-Mobility Semiconductors with Improved Elasticity

引用

MACROMOLECULES 2024年第2期57卷 528-538页

作者： Zhao, Bin Pei, Dandan Shi, Yibo zhang, xuwen zhang, Bo Deng, Yunfeng Han, Yang Geng, Yanhou Tianjin Univ Collaborat Innovat Ctr Chem Sci & Engn Tianjin Sch Mat Sci & Engn Tianjin 300072 Peoples R China Tianjin Univ Tianjin Key Lab Mol Optoelect Sci Tianjin 300072 Peoples R China Collaborat Innovat Ctr Chem Sci & Engn Tianjin Tianjin 300072 Peoples R China BOE Technol Grp Co Ltd BOE Technol Innovat Ctr Beijing 100176 Peoples R China Tianjin Univ Joint Sch Natl Univ Singapore Int Campus Fuzhou 350207 Peoples R China Tianjin Univ Int Campus Fuzhou 350207 Peoples R China

To regulate the mechanical properties of poly(indacenodithiophene-alt-benzothiadizole) (IDT-BT), a high-mobility polymer semiconductor with high ductility but inferior elasticity (plastic deformation onset strain (PdOS) < 10%), triisopropylsilyl (TIPS), hydroxyl (OH), and 2-ureido-4[1H]-pyrimidone (UPy) groups were introduced into its side chain ends. The incorporation of bulky and neutral TIPS groups led to slightly increased ductility but had no obvious influence on the elasticity of the polymer. The presence of OH groups resulted in enhanced elasticity without sacrificing ductility. However, high-content (20 mol %) OH-functionalized side chains were necessary to improve PdOS to above 30% due to the weak and dynamic nature of formed hydrogen bonds. In contrast, incorporating a small amount of UPy groups, capable of forming strong quadruple hydrogen bonds, in side chains could significantly improve the elasticity of the polymer. A PdOS of above 40%, along with a crack onset strain of similar to 100% and decent hole mobility of similar to 0.6 cm(2) V(-1)s(-1), was demonstrated for polymer UPy-5% that contained 5 mol % UPy-functionalized side chains. Because of excellent elasticity, UPy-5% films displayed stable mobility against cyclic stretching, releasing up to 500 cycles at a tensile strain of 30%.

关键词： Deformation Elasticity Nucleic acid structure Polymers Thin films

来源：评论

学校读者我要写书评

暂无评论

Molecular basis and targeted therapies for radioiodine refractory thyroid cancer

引用

ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY 2023年第3期19卷 279-289页

作者： Yu, Qiuxiao zhang, xuwen Li, Li zhang, Chi Huang, Jian Huang, Wenting Chinese Acad Med Sci & Peking Union Med Coll Natl Canc Ctr Dept Pathol Natl Clin Res Ctr CancCanc Hosp Shenzhen 518116 Guangdong Peoples R China Chinese Acad Med Sci & Peking Union Med Coll Shenzhen Hosp Shenzhen 518116 Guangdong Peoples R China

Patients diagnosed with radioiodine refractory thyroid cancer (RAIR-TC) are not amenable to novel I-131 therapy due to the reduced expression of sodium iodide symporter (Na+/I- symporter, NIS) and/or the impairment of NIS trafficking to the plasma membrane. RAIR-TC patients have a relatively poor prognosis with a mean life expectancy of 3-5 years, contributing to the majority of TC-associated mortality. Identifying RAIR-TC patients and selecting proper treatment strategies remain challenging for clinicians. In this review, we demonstrate the updated clinical scenarios or the so-called "definitions" of RAIR-TC suggested by several associations based on I-131 uptake ability and tumor response post-I-131 therapy. We also discuss current knowledge of the molecular alterations involved in membrane-localized NIS loss, which provides a preclinical basis for the development of targeted therapies, in particular, tyrosine kinase inhibitors (TKIs), redifferentiation approaches, and immune checkpoint inhibitors.

关键词： immune checkpoint inhibitors radioiodine refractory thyroid cancer redifferentiation therapies sodium iodide symporter tyrosine kinase inhibitors

来源：评论

学校读者我要写书评

暂无评论

COMPACTNESS OF CAPILLARY HYPERSURFACES WITH MEAN CURVATURE PRESCRIBED BY AMBIENT FUNCTIONS

arXiv

引用

arXiv 2025年

作者： zhang, xuwen Mathematisches Institut Universität Freiburg Ernst-Zermelo-Str.1 Freiburg79104 Germany

We prove a compactness result for capillary hypersurfaces with mean curvature prescribed by ambient functions, which generalizes the results of Schätzle [17] and Bellettini [4] to the capillary case. The proof relies on extending the definition of (unoriented) curvature varifolds with capillary boundary introduced by Wang-zhang [19] to the context of oriented integral varifolds. We also discuss the case when the mean curvature of the boundary is prescribed. MSC 2020: 49Q15, 53C42MSC Codes 49Q15, 53C42 Copyright © 2025, The Authors. All rights reserved.

关键词： Capillarity

来源：评论

学校读者我要写书评

暂无评论

Quinoidal-Diketopyrrolopyrrole-Based Low-Bandgap n-Type Conjugated Polymers via Direct Arylation Polycondensation: Chalcogen Effects on Structures and Properties

引用

MACROMOLECULES 2024年第19期57卷 9006-9016页

作者： Rao, Mei Wang, Pai Shi, Yibo zhang, xuwen Han, Yang Deng, Yunfeng Geng, Yanhou Tianjin Univ Sch Mat Sci & Engn Tianjin Key Lab Mol Optoelect Sci Tianjin 300072 Peoples R China Tianjin Univ Key Lab Organ Integrated Circuits Minist Educ Tianjin 300072 Peoples R China Collaborat Innovat Ctr Chem Sci & Engn Tianjin Tianjin 300072 Peoples R China

Low-bandgap conjugated polymers (CPs) with strong absorption in the short-wave infrared region usually show ambipolar characteristics. Herein, three low-bandgap CPs, that is, PQF, PQT, and PQS, with unipolar n-type transport behavior were synthesized via direct arylation polycondensation (DArP) with quinoids based on terchalcogenophene-flanked diketopyrrolopyrrole (DPP) derivatives as C-Br monomers and less electron-rich (E)-1,2-bis (3,4-difluorothien-2-yl) ethene (4FTVT) as a C-H monomer, and the chalcogen effects on the isomerism of the quinoids and the properties of the resultant CPs were investigated. Thiophene-flanked DPP-containing quinoids are the mixtures of (E, E), (E, Z), and (Z, Z) isomers, while the sole (E, E) isomer is found in furan-flanked DPP-based quinoids and (Z, Z) isomer is dominant in the quinoids based on selenophene-flanked DPP. The quinoidal monomers are stable to undergo DArP. All three CPs show lower bandgaps of similar to 1.1 eV and unipolar n-type transport behavior with field-effect electron mobility (mu e) above 0.1 cm2 V-1 s(-1). Among them, the polymer PQF, comprising furan-flanked DPP, exhibits the highest mu e of 0.21 cm2 V-1 s(-1), possibly attributed to the simple chain conformation. This study provides a strategy to design low-bandgap unipolar n-type polymer semiconductors.

关键词： n-type conjugated polymers quinoidal structures low bandgap direct arylation polycondensation chalcogen effect

来源：评论

学校读者我要写书评

暂无评论

C-H/C-H Oxidative Direct Arylation Polycondensation to Isoindigo-Based n-Type Conjugated Polymers

引用

MACROMOLECULES 2024年第9期57卷 4158-4166页

作者： Shi, Yibo zhang, xuwen Wang, Tianzuo Rao, Mei Han, Yang Deng, Yunfeng Geng, Yanhou Tianjin Univ Sch Mat Sci & Engn Key Lab Organ Integrated Circuits Minist Educ Tianjin 300072 Peoples R China Tianjin Univ Tianjin Key Lab Mol Optoelect Sci Key Lab Organ Integrated Circuits Minist Educ Tianjin 300072 Peoples R China Collaborat Innovat Ctr Chem Sci & Engn Tianjin Tianjin 300072 Peoples R China Tianjin Univ Joint Sch Natl Univ Singapore & Tianjin Univ Int Campus Fuzhou 350207 Peoples R China

Two high molecular weight conjugated polymers (CPs), i.e., poly[N,N '-bis(4-tetradecyloctadecyl)-7,7 '-difluoroisoindigo-alt-2,2 '-bithiazole] (P2FI2Tz) and poly[N,N '-bis(4-tetradecyloctadecyl)-5,5 ',7,7 '-tetrafluoroisoindigo-alt-2,2 '-bithiazole] (P4FI2Tz), were synthesized via C-H/C-H oxidative direct arylation polycondensation (Oxi-DArP) using PdCl2/CuCl/Cu(OAc)(2) as catalytic system and chlorobenzene as solvent. Both polymers are unipolar n-type semiconductors with electron mobility (mu(e)) > 0.2 cm(2) V-1 s(-1), attributed to their low-lying highest occupied molecular orbitals (HOMOs) and lowest unoccupied molecular orbital (LUMOs), which are -6.01/-3.69 and -6.24/-3.82 eV for P2FI2Tz and P4FI2Tz, respectively. P2FI2Tz was also synthesized via C-Br/C-H direct arylation polycondensation (DArP) and Stille polycondensation. The resultant polymers P2FI2Tz-D and P2FI2Tz-S showed slightly lower mu(e) compared to Oxi-DArP-made polymer (P2FI2Tz-O1) with a similar molecular weight. Notably, Oxi-DArP is much faster and more efficient than DArP and Stille polycondensation. P2FI2Tz with a number-average molecular weight (M-n) above 40 kDa, was obtained in 9 h of Oxi-DArP, significantly shorter than 24 h with DArP and Stille polycondensation. P2FI2Tz with a M-n as high as 191 kDa could be synthesized via Oxi-DArP by extending the polymerization time to 16 h. Our results prove Oxi-DArP to be an efficient protocol to synthesize polymer semiconductors. This is also the first comparative study on three methods, i.e., Oxi-DArP, DArP, and Stille polycondensation.

关键词： Condensation Diffraction Monomers Organic reactions Polymers

来源：评论

学校读者我要写书评

暂无评论

Blended Tea Ameliorates T2DM via Modulation of Gut Microflora

引用

PLANT FOODS FOR HUMAN NUTRITION 2024年第4期79卷 851-859页

作者： Liu, Sui Dai, Xinyue Zhao, Jinqi zhang, xuwen Zhu, Mingzhi Wang, Kunbo Fu, Donghe Hunan Agr Univ Key Lab Tea Sci Minist Educ Changsha 410128 Hunan Peoples R China Hunan Agr Univ Natl Res Ctr Engn Technol Utilizat Funct Ingredien Changsha 410128 Hunan Peoples R China Hunan Agr Univ Coinnovat Ctr Educ Minist Utilizat Bot Funct Ingredients Changsha 410128 Hunan Peoples R China Hunan Agr Univ Key Lab Evaluat & Utilizat Gene Resources Hort Cro Minist Agr & Rural Affairs China Changsha 410128 Hunan Peoples R China

Increasing evidences suggest that type 2 diabetes mellitus (T2DM) is closely related to gut microflora dysbiosis, which can be improved by dietary intervention. Four natural plant products, including Cyclocarya paliurus, Fu brick tea, Ampelopsis grossedentata, and Lithocarpus litseifolius, were blended to form a blended tea product for obtaining the better flavor. The blended tea was also expected to have excellent pharmacological activity. Therefore, the ameliorative effect of blended tea on T2DM and underlying mechanisms were studied in this study. The results showed that the blended tea extract effectively attenuated the symptoms of glucose and lipid metabolism-related disorders in T2DM mice fed by high-fat and high-sucrose diet. Furthermore, blended tea extract intervention significantly attenuated gut microbiota dysbiosis, the abundance of bacteria such as Bacteroidetes and Firmicutes, which aid in the hydrolysis and utilization of carbohydrates, significantly increased, while the abundance of pathogenic bacteria such as Proteobacteria significantly decreased. Certain core microorganisms involved in energy metabolism, including Ruminococcaceae_UCG-005, Butyricimonas, Roseburia, Oscillibacter, [Eubacterium]_nodatum_group, Muribaculaceae, Prevotellaceae UCG 001, were also found to be improved by blended tea extract. Collectively, our results demonstrated that the blended tea may ameliorate T2DM through modulation of gut microflora. The blended tea may serve as novel functional drink for the treatment of T2DM and dysbiosis of gut microbiota.

关键词： Blended tea(1) T2DM(2) Gut microflora(3) Gut Microflora dysbiosis(4)

来源：评论

学校读者我要写书评

暂无评论

VARIFOLDS WITH CAPILLARY BOUNDARY

arXiv

引用

arXiv 2025年

作者： Wang, Guofang zhang, xuwen Mathematisches Institut Universität Freiburg Ernst-Zermelo-Str.1 Freiburg79104 Germany

In this paper we introduce and study a new class of varifolds in Rn+1 of arbitrary dimensions and co-dimensions, which satisfy a Neumann-type boundary condition characterizing capillarity. The key idea is to introduce a Radon measure on a subspace of the trivial Grassmannian bundle over the supporting hypersurface as a generalized boundary with prescribed angle, which plays a role as a measure-theoretic capillary boundary. We show several structural properties, monotonicity inequality, boundary rectifiability, classification of tangent cones, and integral compactness for such varifolds under reasonable conditions. This Neumann-type boundary condition fits very well in the context of curvature varifold and Brakke flow, which we also *** Codes 49Q15, 53C42 Copyright © 2025, The Authors. All rights reserved.

关键词： Boundary conditions

来源：评论

学校读者我要写书评

暂无评论

Thienoisoindigo-Based Conjugated Polymers Synthesized by Direct Arylation Polycondensation

引用

MACROMOLECULAR RAPID COMMUNICATIONS 2024年第1期45卷 2300245-2300245页

作者： Wang, Pai Xu, Chenhui zhang, xuwen Shi, Yibo Wang, Cheng Han, Yang Deng, Yunfeng Geng, Yanhou Tianjin Univ Sch Mat Sci & Engn Tianjin 300072 Peoples R China Tianjin Univ Tianjin Key Lab Mol Optoelect Sci Tianjin 300072 Peoples R China Collaborat Innovat Ctr Chem Sci & Engn Tianjin Tianjin 300072 Peoples R China Tianjin Univ Joint Sch Natl Univ Singapore & Tianjin Univ Int Campus Fuzhou 350207 Peoples R China

A series of thienoisoindigo (TIG)-based conjugated polymers (CPs) with high molecular weights are synthesized by direct arylation polycondensation (DArP) by using TIG derivatives as C-Br monomer and multi-halogenated thiophene derivatives, i.e., (E)-1,2-bis(3,4-difluorothien-2-yl)ethene (4FTVT), (E)-1,2-bis(3,4-dichlorothien-2-yl)ethene (4ClTVT), 3,3',4,4'-tetrafluoro-2,2'-bithiophene (4FBT), and 3,3',4,4'-tetrachloro-2,2'-bithiophene (4ClBT), as C-H monomers. Density functional theory (DFT) calculations reveal the high selectivity between alpha-C-H bonds in 4FTVT, 4ClTVT, 4FBT, and 4ClBT and beta-C-H bonds in TIG C-Br monomer. All four resulting CPs exhibit low optical bandgaps of ca. 1.20 eV and ambipolar transport characteristics with both electron and hole mobility above 0.1 cm(2) V-1 s(-1) as elaborated with organic thin-film transistors (OTFTs). The polymer TIG-4FTVT delivers the best device performance. With this polymer, n-channel OTFTs with electron mobility up to 1.67 cm(2) V-1 s(-1) and p-channel OTFTs with hole mobility up to 0.62 cm(2) V-1 s(-1) are fabricated by modifying source/drain electrodes with polyethylenimine ethoxylated (PEIE) and MoO3, respectively, to selectively inject electrons and holes.

关键词： ambipolar polymer semiconductors conjugated polymers direct arylation polycondensation organic thin-film transistors thienoisoindigo

来源：评论

学校读者我要写书评

暂无评论

Boosting catalytic performance of N doped porous carbon derived from coal tar pitch: The role of N species and the contribution of 1O2

引用

JOURNAL OF WATER PROCESS ENGINEERING 2025年 72卷

作者： Huang, Linlin zhang, xuwen Wang, Lin Liu, Tingting Li, Da Sheng, Tao Sun, Caiyu Li, Lixin Heilongjiang Univ Sci & Technol Coll Environm & Chem Engn Harbin 150022 Peoples R China Harbin Inst Technol State Key Lab Urban Water Resource & Environm Harbin 150090 Peoples R China

In this study, nitrogen-doped carbon material (N-PC-d) derived from coal tar pitch using dicyandiamide as N source was successfully synthesized, exhibiting outstanding catalytic performance in the activation of peroxymonosulfate (PMS) for the degradation of Orange G (OG). By optimizing key parameters such as PMS dosage, NPC dosage, nitrogen source, pH, anions, and PS source, the optimal N-PC-d/PMS system achieved a degradation rate 1.45 times higher than that of the PC/PMS system within a broad pH range (2.0-10.0). Through electron paramagnetic resonance (EPR) and quenching experiments, it was found that singlet oxygen (1O2) was the predominant species accountable for OG degradation, while reactive oxygen species (ROS), including superoxide (O2 & sdot;-), hydroxyl radicals (& sdot;OH), and sulfate radicals (SO4 & sdot;-), played auxiliary roles. Moreover, the structure-activity relationship analysis revealed that functional groups such as C--C, C--O, and pyridine N were mainly involved in PMS activation. The degradation mechanism of OG was further elucidated by high-performance liquid chromatography-mass spectrometry (HPLC-MS). This research presented a cost-efficient N-doped porous carbon material for environmental remediation and provides more profound insights into the mechanisms of PMS activation by N doped carbon-based materials.

关键词： N-doped porous carbon Coal tar pitch PMS Singlet oxygen Orange G

来源：评论

学校读者我要写书评

暂无评论

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案：

请选择收藏分类：

通借通还

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：