检索结果-内蒙古大学图书馆

The Role of Glutathione S-Transferase in the Regulation of Plant Growth, and Responses to Environmental Stresses

Phyton-International Journal of Experimental Botany 2025年第3期94卷 583-601页

作者： Chen Lin Zidan Zhang zhao Zhang Yuxiang Long xuwen Shen Jinghao Zhang Youping Wang Key Laboratory of Plant Functional Genomics of the Ministry of Education Yangzhou UniversityYangzhou225009China Jiangsu Key Laboratory of Crop Genomics and Molecular Breeding Yangzhou UniversityYangzhou225009China

Glutathione S-transferases (GSTs) represent a large and diverse enzyme family ubiquitously distributed across the plant kingdom. These proteins catalyze the conjugation of glutathione (GSH) with electrophilic substrates in response to various stress conditions. Beyond their role in stress adaptation, certain GSTs are integral regulators of plant growth and development, contributing to a range of physiological processes. Most GST proteins exhibit dual enzymatic activities, functioning as both transferases and peroxidases, which enables their involvement in diverse cellular processes, including detoxification and stress responses. Recent advancements, particularly in X-ray crystallography, have enabled detailed structural analysis of GST proteins, significantly enhancing our understanding of their biological functions. This review offers a comprehensive overview of the classification and structural characteristics of GSTs in plants. It also highlights recent findings on their roles in plant growth and development, cell signaling, catalytic transport, and stress tolerance. Furthermore, key scientific challenges related to GSTs are discussed, focusing on their potential applications in agriculture. These insights aim to facilitate the screening of functional GST genes and support molecular breeding efforts across diverse crop species.

关键词： Glutathione S-transferase biotic and abiotic stress plant growth and development signal transduction biological functions

来源：评论

学校读者我要写书评

暂无评论

Energy Driving-Damage Degradation-Structural Failure Mechanism of Layered Sandstones Under Uniaxial Conditions

引用

ROCK MECHANICS AND ROCK ENGINEERING 2025年第3期58卷 3815-3853页

作者： Song, Zhixiang Zhang, Junwen Wu, Shaokang zhao, Shankun Zhang, Yang Dong, Xukai Zhang, xuwen Wang, Sihe China Univ Min & Technol Beijing Sch Energy & Min Engn Beijing 100083 Peoples R China China Coal Res Inst Mine Safety Technol Branch Beijing 100013 Peoples R China

It is of great theoretical significance to effectively reveal the energy driving-damage degradation-structural failure mechanism of rocks for the probability evaluation and prevention of rock burst in deep coal mines. Therefore, uniaxial loading and unloading tests of layered sandstones were conducted. Subsequently, the progressive failure process and stress-strain curves were obtained. Then, the evolution characteristics of strength, strain, energy, damage and macroscopic failure was characterized. Meanwhile, the damage proportion at each stage was quantified, and the linear damage deterioration law was obtained. Finally, the energy driving-damage degradation-structural failure mechanism was revealed. The results showed that: (1) increasing the unloading stress level did not necessarily reduce the bearing capacity, but the unloading effect could significantly affect the energy storage capacity;(2) there was the significant linear evolution relationship between the damage proportion and the unloading stress level under identical inclination angle in stages II and IV;(3) When the unloading stress level was over 0.7, the pre-peak structural adjustment behavior could strengthen the stability of post-peak structures and reduce the impact degree of rock burst. The conclusions could provide certain of theoretical basis for the prevention of rock burst in deep coal mines.

关键词： Structural evolution Unloading stress level Linear damage deterioration law Energy driving-damage degradation-structural failure mechanism Rock burst

来源：评论

学校读者我要写书评

暂无评论

Optimising maize threshing by integrating DEM simulation and interpretive enhanced predictive modelling

引用

BIOSYSTEMS ENGINEERING 2024年 244卷 93-106页

作者： Fang, xuwen Zhang, Jinsong zhao, Xuelin Zhang, Li Zhou, Deyi Yu, Chunsheng Hu, Wei Zhang, Qiang Jilin Univ Coll Biol & Agr Engn Changchun 130022 Peoples R China

Maize threshing is a complex and dynamic process, and optimisation of operating parameters is essential to improve threshing quality and efficiency. In this study, machine learning was combined with interpretability analysis to investigate the dynamic effects of operating parameters on maize threshing quality and to optimise the threshing process. The maize cob model used to simulate threshing was validated by stacking angle and tensile test. Real-time drum operating parameters and threshing quality data obtained through Discrete Element Method (DEM) threshing simulation were used to train a threshing quality prediction network. The prediction accuracy was improved by incorporating an attention mechanism into the Long Short-Term Memory (LSTM) model with an optimised Root Mean Square Error (RMSE) of 0.0041. The global feature importance and dynamic Shapley Additive Explanations (SHAP) value analyses demonstrated that rotational speed is a key determinant of unthreshed and damaged rates and that its effect varies significantly at different stages of the threshing process. Guided by these analyses, a staged speed adjustment experiment was conducted. Specifically, an increase in rotational speed during the initial threshing phase markedly lowered the initial unthreshed rate for medium and high-speed groups to 6.63% and 2.73%, respectively, a significant improvement over the 67.70% observed in the low-speed group. The final damage rate in the high-speed group decreased by 9.79% relative to the low-speed group. This dynamic analysis approach provides a novel paradigm for optimising complex agricultural processes under varying conditions, offering interpretable insights for precise process control and improvement.

关键词： Simulation Neural network forecast Game theory Agricultural optimisation Interpretable models Data-driven agriculture

来源：评论

学校读者我要写书评

暂无评论

Cardiovascular toxicity in antitumor therapy: biological and therapeutic insights

引用

TRENDS IN CANCER 2024年第10期10卷 920-934页

作者： Lin, xuwen Ma, Xidong zhao, Sheng Yao, Jie Han, Leng Jing, Ying Xue, Xinying Capital Med Univ Beijing Shijitan Hosp Emergency & Crit Care Med Ctr Dept Resp & Crit Care Beijing Peoples R China Chinese Acad Med Sci & Peking Union Med Coll Fuwai Hosp Natl Ctr Cardiovasc Dis State Key Lab Cardiovasc DisDept Cardiol Beijing Peoples R China Shandong Second Med Univ Dept Resp & Crit Care Weifang Peoples R China Indiana Univ Brown Ctr Immunotherapy Sch Med Indianapolis IN 46202 USA Indiana Univ Sch Med Dept Biostat & Hlth Data Sci Indianapolis IN 46202 USA Fudan Univ Greater Bay Area Inst Precis Med Guangzhou Ctr Intelligent Med Res Sch Life Sci Guangzhou Peoples R China

The evolution of antitumor therapies has significantly improved cancer prognosis but has concurrently resulted in cardiovascular toxicities. Understanding the biological mechanisms behind these toxicities is crucial for effective management. Immunotherapy-related cardiovascular toxicities are primarily mediated by immune cells and secreted cytokines. Chemotherapy may cause cardiovascular damage through autophagy disruption and mitochondrial dysfunction. Targeted therapies can induce toxicity through endothelin-1 (ET-1) production and cardiac signaling disruption. Radiotherapy may lead to cardiomyopathy and myocardial fibrosis by affecting endothelial cells, triggering inflammatory responses and accelerating atherosclerosis. This review provides insights into these mechanisms and strategies, aiming to enhance the clinical prevention and treatment of cardiovascular toxicities.

关键词： cardiovascular toxicities immunotherapy chemotherapy radiotherapy targeted therapy biological mechanisms

来源：评论

学校读者我要写书评

暂无评论

Side-Chain-Functionalized Poly(indacenodithiophene-alt-benzothiadizole)s as Stretchable High-Mobility Semiconductors with Improved Elasticity

引用

MACROMOLECULES 2024年第2期57卷 528-538页

作者： zhao, Bin Pei, Dandan Shi, Yibo Zhang, xuwen Zhang, Bo Deng, Yunfeng Han, Yang Geng, Yanhou Tianjin Univ Collaborat Innovat Ctr Chem Sci & Engn Tianjin Sch Mat Sci & Engn Tianjin 300072 Peoples R China Tianjin Univ Tianjin Key Lab Mol Optoelect Sci Tianjin 300072 Peoples R China Collaborat Innovat Ctr Chem Sci & Engn Tianjin Tianjin 300072 Peoples R China BOE Technol Grp Co Ltd BOE Technol Innovat Ctr Beijing 100176 Peoples R China Tianjin Univ Joint Sch Natl Univ Singapore Int Campus Fuzhou 350207 Peoples R China Tianjin Univ Int Campus Fuzhou 350207 Peoples R China

To regulate the mechanical properties of poly(indacenodithiophene-alt-benzothiadizole) (IDT-BT), a high-mobility polymer semiconductor with high ductility but inferior elasticity (plastic deformation onset strain (PdOS) < 10%), triisopropylsilyl (TIPS), hydroxyl (OH), and 2-ureido-4[1H]-pyrimidone (UPy) groups were introduced into its side chain ends. The incorporation of bulky and neutral TIPS groups led to slightly increased ductility but had no obvious influence on the elasticity of the polymer. The presence of OH groups resulted in enhanced elasticity without sacrificing ductility. However, high-content (20 mol %) OH-functionalized side chains were necessary to improve PdOS to above 30% due to the weak and dynamic nature of formed hydrogen bonds. In contrast, incorporating a small amount of UPy groups, capable of forming strong quadruple hydrogen bonds, in side chains could significantly improve the elasticity of the polymer. A PdOS of above 40%, along with a crack onset strain of similar to 100% and decent hole mobility of similar to 0.6 cm(2) V(-1)s(-1), was demonstrated for polymer UPy-5% that contained 5 mol % UPy-functionalized side chains. Because of excellent elasticity, UPy-5% films displayed stable mobility against cyclic stretching, releasing up to 500 cycles at a tensile strain of 30%.

关键词： Deformation Elasticity Nucleic acid structure Polymers Thin films

来源：评论

学校读者我要写书评

暂无评论

Blended Tea Ameliorates T2DM via Modulation of Gut Microflora

引用

PLANT FOODS FOR HUMAN NUTRITION 2024年第4期79卷 851-859页

作者： Liu, Sui Dai, Xinyue zhao, Jinqi Zhang, xuwen Zhu, Mingzhi Wang, Kunbo Fu, Donghe Hunan Agr Univ Key Lab Tea Sci Minist Educ Changsha 410128 Hunan Peoples R China Hunan Agr Univ Natl Res Ctr Engn Technol Utilizat Funct Ingredien Changsha 410128 Hunan Peoples R China Hunan Agr Univ Coinnovat Ctr Educ Minist Utilizat Bot Funct Ingredients Changsha 410128 Hunan Peoples R China Hunan Agr Univ Key Lab Evaluat & Utilizat Gene Resources Hort Cro Minist Agr & Rural Affairs China Changsha 410128 Hunan Peoples R China

Increasing evidences suggest that type 2 diabetes mellitus (T2DM) is closely related to gut microflora dysbiosis, which can be improved by dietary intervention. Four natural plant products, including Cyclocarya paliurus, Fu brick tea, Ampelopsis grossedentata, and Lithocarpus litseifolius, were blended to form a blended tea product for obtaining the better flavor. The blended tea was also expected to have excellent pharmacological activity. Therefore, the ameliorative effect of blended tea on T2DM and underlying mechanisms were studied in this study. The results showed that the blended tea extract effectively attenuated the symptoms of glucose and lipid metabolism-related disorders in T2DM mice fed by high-fat and high-sucrose diet. Furthermore, blended tea extract intervention significantly attenuated gut microbiota dysbiosis, the abundance of bacteria such as Bacteroidetes and Firmicutes, which aid in the hydrolysis and utilization of carbohydrates, significantly increased, while the abundance of pathogenic bacteria such as Proteobacteria significantly decreased. Certain core microorganisms involved in energy metabolism, including Ruminococcaceae_UCG-005, Butyricimonas, Roseburia, Oscillibacter, [Eubacterium]_nodatum_group, Muribaculaceae, Prevotellaceae UCG 001, were also found to be improved by blended tea extract. Collectively, our results demonstrated that the blended tea may ameliorate T2DM through modulation of gut microflora. The blended tea may serve as novel functional drink for the treatment of T2DM and dysbiosis of gut microbiota.

关键词： Blended tea(1) T2DM(2) Gut microflora(3) Gut Microflora dysbiosis(4)

来源：评论

学校读者我要写书评

暂无评论

A review: The structures and bioactivities of steroidal saponins from Allium macrostemon Bulbus

引用

PHYTOCHEMISTRY LETTERS 2023年第1期57卷 210-226页

作者： Xie, Huili Shi, Xiaolei zhao, Dexin Wang, Bingzi Jin, Yongri Li, xuwen Jilin Univ Coll Chem 2519 Jiefang Rd Changchun 130021 Peoples R China Jilin Univ Coll Food Sci & Engn Changchun 130062 Peoples R China

Allium macrostemon Bulbus (Xiebai in Chinese), as an important medicinal and edible homologous plant, has two kinds of original plants (the dry bulbs of Allium macrostemon and Allium chinense). In China, the dry bulbs of Allium macrostemon and Allium chinense have been used to treat some diseases for thousands of years. Steroidal saponins are considered to be one type of their most important active ingredients and research into the phar-macological activities of these compounds are currently undertaken. Some steroidal saponins may be promising therapeutic tools, which has caught the attention of researchers. This article provides a comprehensive overview of 102 steroidal saponins and sapogenins found in Allium macrostemon Bulbus, along with their reported phar-macological activities, including anti-inflammatory, antioxidant, antiplatelet aggregation, blood lipid-lowering, antitumor, and other beneficial effects. In this review, the extraction and isolation, spectral characteristics and pharmacological activities of steroidal saponins have been summarized based on literature from 1989 to 2022.

关键词： Allium macrostemon Bulbus Allium macrostemon Allium chinense Steroidal Saponins Chemical structure Bioactivity

来源：评论

学校读者我要写书评

暂无评论

Maize kernel damage dynamic prediction in threshing through PSO-LSTM and discrete element modelling

引用

BIOSYSTEMS ENGINEERING 2024年 242卷 179-195页

作者： Fang, xuwen Zhang, Jinsong zhao, Xuelin Zhang, Qiang Zhang, Li Zhou, Deyi Yu, Chunsheng Hu, Wei Wang, Hao Jilin Univ Coll Biol & Agr Engn Changchun 130022 Peoples R China

This study presents the development of a maize ear model and a predictive approach for kernel damage in maize threshing, integrating physical simulation and predictive analytics to understand better and forecast threshingrelated damage. First, a maize ear model was developed to analyse kernel damage during threshing. Through the angle of repose experiments, the optimal number of spheres for the kernel model was established as 65. Tensile tests were conducted to evaluate the kernel-cob bond strength, revealing an average relative error in the bonding force of 8.71%. Vogel impact energy modelling was applied to the kernel threshing process to determine kernel damage. The correlation between the speed of seed grain movement and the occurrence of damage was analysed by post-processing to identify locations with frequent kernel damage in the drum. In-depth data analysis of kernel damage in the threshing drum further elucidates the inherent relationship between kernel velocity and damage extent. The study then focused on applying neural networks to predict damage rates. The comparative evaluation shows that the PSO-LSTM model has better prediction accuracy than LSTM and RNN models, with the PSO-LSTM network achieving an RMSE of 0.096, a R2 of 99.96%, and a final damage rate of 2.41% in validation tests. Threshing experiments were conducted to verify the model, showing a 1.4% discrepancy between predicted and actual damage rates. This study proposes a kernel damage prediction model and provides new insights and directions for the structural design of threshing drums.

关键词： Maize threshing Kernel damage prediction Machine learning in agriculture Agricultural automation LSTM network

来源：评论

学校读者我要写书评

暂无评论

Effects of build direction and microstructure on fatigue crack growth behavior of Ti6Al4V fabricated by laser powder bed fusion

引用

FATIGUE & FRACTURE OF ENGINEERING MATERIALS & STRUCTURES 2024年第7期47卷 2396-2410页

作者： Xie, Peidong Xie, Deqiao Zhou, Kai Gu, xuwen Naqvi, Syed Mesum Raza Shen, Lida Tian, Zongjun zhao, Jianfeng Nanjing Univ Aeronaut & Astronaut Coll Mech & Elect Engn Nanjing Peoples R China Nanjing Univ Aeronaut & Astronaut Coll Astronaut Nanjing 210016 Peoples R China Nanjing Univ Aeronaut & Astronaut Wuxi Res Inst Wuxi Peoples R China Natl Ctr Supervis & Inspect Addit Mfg Prod Qual Wuxi Peoples R China

This study compares the fatigue crack growth (FCG) behavior of Ti6Al4V parts fabricated by laser powder bed melting (LPBF) with four build directions (0 degrees, 30 degrees, 60 degrees, and 90 degrees) and two heat treatments and analyzed the effect of build direction and microstructure on FCG. The results show that the build direction has a significant effect on the FCG rate. Particularly, specimens with 90 degrees build direction have the best FCG resistance while the 0 degrees specimens have the worst. Furthermore, the fragile deposition layer boundary is the main cause of the crack deflection. The microstructure shows that the columnar beta grains have less effect on FCG. The increase in resistance to FCG after heat treatment is attributed to the lath-like alpha grains consuming the energy for FCG. As compared to needle-like alpha ' grains, the lath-like alpha grains are more likely to initiate intergranular fracture and secondary cracking, leading to rugged crack tip paths. The effect of build direction on FCG of LPBF-Ti6Al4V part is significant. The heat-treated lath-like alpha grains have better resistance to FCG. Cracks tend to expand in the direction of parallel deposition layers. Secondary cracking is related to build direction and microstructure.

关键词： build direction fatigue crack growth LPBF microstructure Ti6Al4V

来源：评论

学校读者我要写书评

暂无评论

Adsorption of Orange G on Activated Porous Carbon Derived from Coal Tar Pitch: Experimental and DFT Study

引用

LANGMUIR 2024年第48期40卷 25471-25482页

作者： Huang, Linlin Zhang, xuwen Liu, Tingting Wang, Lin Li, Lixin Li, Da Sheng, Tao Dong, Zilong zhao, Xinyue Heilongjiang Univ Sci & Technol Coll Environm & Chem Engn Harbin 150022 Peoples R China Harbin Inst Technol State Key Lab Urban Water Resource & Environm Harbin 150000 Peoples R China Northeast Agr Univ Sch Resources & Environm Harbin 150030 Peoples R China

A coal tar pitch-based porous carbon adsorbent (CPA) was synthesized through a straightforward method involving the heating of a mixture of KOH and coal tar pitch (CTP). This CPA exhibited a high surface area of 1811.2 m2 g-1 and a large pore volume of 0.94 cm3 g-1 when prepared with a CTP to KOH mass ratio of 1:4 at 800 degrees C. Parameters such as the heating temperature and activator dose were optimized to enhance the adsorption efficiency. The prepared CPA was extensively characterized by SEM, XRD, FTIR, and BET measurements. Notably, CPA presented a distinct adsorption performance for Orange G (OG), achieving a maximum adsorption capability of 449.7 mg g-1. Kinetic studies indicated that the adsorption process followed the pseudo-second-order model, while the adsorption isotherm data demonstrated that both chemical and physical interactions favored OG adsorption. Thermodynamic analysis revealed that the adsorption of OG on CPA was spontaneous and exothermic and increased the entropy. Density functional theory (DFT) calculations provided insights into the adsorption mechanism, highlighting electrostatic interactions, hydrogen bonds, and pi-pi interactions as the dominant processes governing OG adsorption onto the adsorbent.

关键词： Potassium hydroxide

来源：评论

学校读者我要写书评

暂无评论

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案：

请选择收藏分类：

通借通还

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：