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南京农业大学学报 2015年第5期38卷 864-868页

作者：郑尧张永泉陈家长邴旭文尹家胜王在照农业部淡水水产生物技术与遗传育种重点实验室/中国水产科学研究院黑龙江水产研究所黑龙江哈尔滨150070 中国水产科学研究院淡水渔业研究中心/农业部长江下游渔业资源环境科学观测实验站/中国水产科学研究院内陆渔业生态环境和资源重点开放实验室江苏无锡214081 西北农林科技大学动物科技学院/陕西省农业分子生物学重点实验室陕西杨凌712100

[目的]本文旨在比较实验室和池塘养殖F1代,高、低密度实验室养殖F2代雌、雄鱼在激素含量和芳香化酶活力上的差异。[方法]采用ELISA方法对激素含量和芳香化酶活力进行了检测。[结果]发现实验室养殖F1代雌鱼全鱼组织雌二醇(E2)含量极显著... 详细信息

[目的]本文旨在比较实验室和池塘养殖F1代,高、低密度实验室养殖F2代雌、雄鱼在激素含量和芳香化酶活力上的差异。[方法]采用ELISA方法对激素含量和芳香化酶活力进行了检测。[结果]发现实验室养殖F1代雌鱼全鱼组织雌二醇(E2)含量极显著高于雄鱼(P<0.01)。池塘养殖F1代雌鱼脑中E2和睾酮(T)含量均极显著高于雄鱼,且卵巢中的芳香化酶活力极显著低于雄鱼(P<0.01)。低密度养殖组F2代中卵巢T含量极显著低于高密度养殖组精巢中的含量(P<0.01)。低密度养殖组F2代雌鱼脑、卵巢中的E2含量分别极显著高于高密度养殖组F2代雄鱼脑、精巢中的含量(P<0.01)。F2代雌鱼脑中的芳香化酶活力极显著低于雄鱼中的,但卵巢中的芳香化酶活力极显著高于精巢中的(P<0.01)。[结论]实验室和池塘养殖F1代,高、低密度实验室养殖F2代雌、雄鱼激素含量和芳香化酶活力存在差异。

关键词：雌核发育彭泽鲫睾酮雌二醇芳香化酶

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Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health 2015年第1期5卷 88-88页

作者： Liu, Lei Zhang, Xuezhen Yang, JinYing Qian, Xueya zheng, zheng Tang, xuwen Liu, Huishu Guangzhou Women and Children’s Medical Center Guangzhou Medical University Guangzhou China

Objectives Subclinical thyroid disorders are common in pregnant women, which are associated with adverse pregnancy outcomes. Physiological changes in pregnancy and the lack of pregnancy-specific reference ranges pose great challenge for the managements of subclinical thyroid disorders in pregnancy. We aimed to establish trimester-specific thyroid hormone reference intervals throughout pregnancy in southern Chinese population. Methods we measured the serum thyroid hormone (TSH, FT4, TPO-AB) using Abbott electrochemiluminescence immunoassay in 5589 pregnant women during 2012–2013. Patients with known thyroid disorders, autoimmune disease, recurrent miscarriage, hyperemesis gravidarum and pre-eclampsia were excluded. Trimester-specific reference ranges (2.5th, 97.5th centiles) were calculated. Results TSH median T1: 1.19 ± 0.99 mIU/L ( N = 3532), T2: 1.40 ± 1.02 mIU/L ( N = 1623), T3: 1.48 ± 1.30 mIU/L ( N = 434). FT4 median T1: 15.7 ± 3.12 pmol/L ( N = 3532), T2: 13.81 ± 2.99 pmol/L ( N = 1623), T3: 12.92 ± 2.98 pmol/L ( N = 434). TSH reference range T1: 0.01–3.55 mIU/L, T2: 0.01–4.13 mIU/L, T3: 0–4.67 mIU/L. FT4 reference range T1: 12–21.44pmol/L, T2: 10.01–19.36 pmol/L, T3: 9.29–20.31 pmol/L. TSH slightly increased throughout gestation. FT4 decreased throughout gestation. Conclusions We established pregnancy-specific thyroid function reference intervals of southern Chinese population, which is beneficial in clinical practice. Disclosures L. Liu: None. X. Zhang: None. J. Yang: None. X. Qian: None. Z. zheng: None. X. Tang: None. H. Liu: None.

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Research on the performance of DSP parallel system

Research on the performance of DSP parallel system

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2013 3rd International Conference on Advanced Measurement and Test, AMT 2013

作者： Xiaoqun, Sun Qiang, Wu xuwen, Li Xin, zheng College of Electronic and Control Engineering of Beijing University of Technology Beijing China College of Life Science and Bioengineering of Beijing University of Technology Beijing China

ISBN: (纸本)9783037857168

This paper introduces the performance metric of DSP parallel processing system and presents a model of coarse-grained speedup of DSP parallel processing structure. Quantitative research is done according to the system performance index and target program features. This study simulates and analyzes different communication protocols and different influences of different degrees of parallelism on the parallel processing structure performances. Optimization direction of parallel processing system is put forward. © (2013) Trans Tech Publications Switzerland.

关键词： Parallel processing systems

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Research on the Performance of DSP Parallel System

Research on the Performance of DSP Parallel System

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2013 3rd International Conference on Advanced Measurement and Test(AMT 2013)

作者： Sun Xiaoqun Wu Qiang Li xuwen zheng Xin College of Electronic and Control Engineering of Beijing University of Technology College of Life Science and Bioengineering of Beijing University of Technology

This paper introduces the performance metric of DSP parallel processing system and presents a model of coarse-grained speedup of DSP parallel processing *** research is done according to the system performance index and target program *** study simulates and analyzes different communication protocols and different influences of different degrees of parallelism on the parallel processing structure *** direction of parallel processing system is put forward.

关键词： Parallel system performance Speedup ratio Communication protocol

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Downregulation of Skp2 inhibits the growth and metastasis of gastric cancer cells in vitro and in vivo

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TUMOR BIOLOGY 2013年第1期34卷 181-192页

作者： Wei, zheng Jiang, Xian Liu, Fengjun Qiao, Haiquan Zhou, Baoguo Zhai, Bo Zhang, Lianfeng Zhang, xuwen Han, Likun Jiang, Hongchi Krissansen, Geoffrey W. Sun, Xueying Harbin Med Univ Affiliated Hosp 1 Dept Gen Surg Hepatosplen Surg Ctr Harbin 150001 Peoples R China Shandong Univ Qilu Hosp Dept Gen Surg Jinan 250100 Peoples R China Univ Auckland Fac Med & Hlth Sci Dept Mol Med & Pathol Auckland 1005 New Zealand

S-phase kinase-associated protein-2 (Skp2) is overexpressed in human cancers and associated with poor prognosis. Skp2 acts as an oncogenic protein by enhancing cancer cell growth and tumor metastasis. The present study has demonstrated that small hairpin RNA (shRNA)-mediated downregulation of Skp2 markedly inhibits the viability, proliferation, colony formation, migration, invasion, and apoptosis of human gastric cancer MGC803 cells, which express a high level of Skp2. In contrast, Skp2 shRNA had only a slight effect on the above properties of BGC823 cells, which express a low level of Skp2. In accord, knockdown of Skp2 suppressed the ability of MGC803 cells to form tumors and to metastasize to the lungs of mice, and the growth of established tumors, by inhibiting cell proliferation and enhancing cell apoptosis. In contrast, overexpression of Skp2 promoted tumorigenesis of BGC823 cells in mice. Skp2 depletion induced cell cycle arrest in the G(1)/S phase by upregulating p27, p21, and p57 and downregulating cyclin E and cyclin-dependent kinase 2. Skp2 depletion also increased caspase-3 activity, impeded the ability of cells to form filopoidia and locomote, upregulated RECK (reversion-inducing cysteine-rich protein with kazal motifs), and downregulated matrix metalloproteinase (MMP)-2 and MMP-9 activity and expression. The results suggest that downregulating Skp2 warrants investigation as a promising strategy to treat gastric cancers that express high levels of Skp2.

关键词： S-phase kinase-associated protein-2 Gastric cancer Proliferation Cell cycle Metastasis p27

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Research on soot of black smoke from ceramic furnace flue gas: Characterization of soot

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JOURNAL OF HAZARDOUS MATERIALS 2012年 199卷 272-281页

作者： Lu, Pei Li, Caiting Zeng, Guangming Xie, xuwen Cai, Zhihong Zhou, Yangxin Zhao, Yapei Zhan, Qi Zeng, zheng Hunan Univ Coll Environm Sci & Engn Changsha 410082 Hunan Peoples R China Hunan Univ Minist Educ Key Lab Environm Biol & Pollut Control Changsha 410082 Hunan Peoples R China

In this study, the characterizations of soot from ceramic furnace flue gas were studied using environmental scanning electron microscopy, energy dispersive spectroscopy, particle size distribution, specific surface area measurements, crystal characterizations and organic pollutant analysis. Soot particles were mainly spherical nanoparticles with diameters less than 100 nm. However, the particles could be aggregated into larger ones with a median diameter of 3.66 mu m. Nanometer pores with diameters ranging 2-4 nm were also detected in the soot particles. Because of their large surface areas and pore volumes, other pollutants in the environment can be adsorbed to soot particles potentially making them more hazardous. Several elements, including C, O and Pb, were detected in the soot, but only small amounts of crystalline materials were observed. This is because most of the detected carbon and metals/metal oxides/metal salts were amorphous. Approximately 90 different organic pollutants were detected in the soot, including aromatic compounds and other hydrocarbons. Because of the carcinogenic properties of aromatic compounds and the photochemical effects of hydrocarbons, soot could have serious health and environmental impacts. The results suggest that soot particles are hazardous material and urgently need to be controlled. (C) 2011 Elsevier B.V. All rights reserved.

关键词： Soot Nanoparticle Organic compounds Hazardous materials

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The Influenceof Rare Earth Element on α-Solidification of A356 Alloy

The Influenceof Rare Earth Element on α-Solidification of A...

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International Conference on Advances in Materials and Manufacturing Processes

作者： zheng, Zhiqiang Xiong, Xingen Chen, Keming Li, xuwen Nanchang Univ Nanchang 330031 Peoples R China

ISBN: (纸本)9780878492039

The Influenceof Rare Earth Element on alpha-Solidification of A356 Alloy has been discussed in the paper. It is showed by the research, that the condition of interphase is changed by Rare Earth element asymmetry distribution, which influences the process of a phase growing and facilitates the growth of alpha phase in sphere, and leads to a optimal Rare Earth quantity for facilitative effect, which is 0.5% in this experimentation, and that alpha phase grain will be change to small by adding Rare Earth.

关键词： semi-solid aluminum silicon alloy solidify Rare Earth

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The Optimization of the Technologic Parameter in Strong Cooling with Single-tube on the A356 Alloy

The Optimization of the Technologic Parameter in Strong Cool...

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International Conference on Advances in Materials and Manufacturing Processes

作者： zheng, Zhiqiang Xiong, Xingen Chen, Keming Lin, Bojun Li, xuwen Nanchang Univ Nanchang 330031 Peoples R China

ISBN: (纸本)9780878492039

The tube spread around strong cooling technology is new technology of the making semisolid slurry and semisolid billet in Semi-Solid Processing. The technologic parameter of its on the A356 Alloy is researched in the article. It is showed by the result of the experimentation: that the fine and form verge on rotundity crystal grain is made at 180L/h and at 640-650 degrees C. It has met all the conditions in the semi-solid processing on semisolid billet. Semi-solid forming technology has been called the "new metal processing technology in the 21st century", which in foreign countries has certain industrial applications. In 1996 in the United States the sales of semi-solid casting was up to 1 billion dollars. But the industrial application in China is almost empty, one of the most important reasons is: the preparation of slurry or billet is too complicated or cost of production is too high, so that semi-solid forming technology in China has suffered serious setbacks on the road of industrialization. According to this situation, we have done a little attempts on manufacturing slurry and billet of semi-solid forming and have developed a new technology of spread around strong cooling whose intellectual property rights belong to us, equipment production is simple and the process is easy to control and the semi-solid slurry is east to prepare continuously. It will be discussed in this paper that process parameters of the single-tube strong cooling impacts on the microstructure of semi-solid

关键词： strong cooling with single-tube semi-solid A356 alloy technologic parameter microstructure

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恩格斯以权威的客观必然性为核心的领导哲学

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河南科技学院学报（社会科学版） 2011年第11期31卷 21-25页

作者：刘仁营李勐郑正真吴旭文江西师范大学政法学院江西南昌330022

恩格斯的管理哲学主要涉及到领导哲学领域,它以领导权威的客观必然性作为理论轴心,系统地阐发了权威的本质、权威的形成、权威的存在形式、权威与自治的关系等基本问题,在时间上涉及到人类发展的整个历史,在内容上涉及到政治管理、经济... 详细信息

恩格斯的管理哲学主要涉及到领导哲学领域,它以领导权威的客观必然性作为理论轴心,系统地阐发了权威的本质、权威的形成、权威的存在形式、权威与自治的关系等基本问题,在时间上涉及到人类发展的整个历史,在内容上涉及到政治管理、经济管理等广泛领域,从而形成一个具有较为完整和充分的理论体系。

关键词：恩格斯领导哲学权威

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无溶剂法合成高纯度蔗糖脂肪酸酯

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化工生产与技术 2010年第4期17卷 23-24,27页

作者：严量郑彤周志勇李旭文浙江迪耳化工有限公司浙江金华321016

采用无溶剂法合成了蔗糖脂肪酸酯。以氢化油为原料,经与甲醇反应制得脂肪酸甲脂,然后在新型催化剂存在下与蔗糖于130～140℃、-0.1 MPa条件下进行酯交换反应,当脂肪酸甲酯加入量为100 g(脂肪酸甲酯和蔗糖的摩尔比为1.0/1.27)、催化剂加... 详细信息

采用无溶剂法合成了蔗糖脂肪酸酯。以氢化油为原料,经与甲醇反应制得脂肪酸甲脂,然后在新型催化剂存在下与蔗糖于130～140℃、-0.1 MPa条件下进行酯交换反应,当脂肪酸甲酯加入量为100 g(脂肪酸甲酯和蔗糖的摩尔比为1.0/1.27)、催化剂加入量为2.6g、皂盐加入量为12 g时,合成的SE经有机溶剂处理总蔗糖酯质量分数可达91.6%,单酯的质量分数可达65%,产品收率达到48%左右,各项质量指标均符合GB 8272—87要求。将试验结果应用于生产,取得了良好的效果。

关键词：蔗糖脂肪酸酯氢化油无溶剂法催化剂

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