检索结果-内蒙古大学图书馆

A General Route for Chemiluminescence of n-Type Au Nanocrystals

ANALYTICAL CHEMISTRY 2022年第24期94卷 8811-8817页

作者： Fu, Li zhang, Bin Gao, xuwen Dong, Shuangtian Wang, Dongyang Zou, Guizheng Shandong Univ Sch Chem & Chem Engn Jinan 250100 Peoples R China

cence from nanocrystals (NCs) have been extensively exploited for both fundamental and applied investigation over two decades, while the understanding of chemiluminescence (CL) from NCs is still far from clear by now. Herein, a general route for triggering CL from NC luminophore is proposed by extensively exploiting the charge transfer between n-type NCs and oxidants. Oxidants, such as K2S2O8, H2O2, KMnO4, and NaClO, can chemically inject the hole onto the valence band (VB) of methionine-capped n-type AuNCs (Met@ AuNCs) and enable the occurrence of efficient radiative-charge-recombination between the chemically injected exogenous VB hole and the pre-existed endogenous conduction band (CB) electron, which eventually results in single-color and defect-involved CL with the maximum emission wavelength around 824 nm. The CL of Met@AuNCs/oxidant is qualified for ultrasensitive CL immunoassay in a similar procedure to the biotin???avidin and magnetic separation involved commercial CL immunoassay and exhibits acceptable performance for linearly determining carcinoembryonic antigen from 50 pg/mL to 100 ng/mL with a limit of detection of 10 pg/mL (S/N = 3). This strategy provides a general route to develop nanoparticulate CL luminophores and might eventually enable CL multiplexing assay via extensively exploiting the CL of different wavebands.

关键词： Nanocrystal Electrochemiluminescence Electroluminescence Chemiluminescence

来源：评论

学校读者我要写书评

暂无评论

Highly Efficient Wavelength-Resolved Electrochemiluminescence of Carbon Nitride Films for Ultrasensitive Multiplex MicroRNA Detection

引用

ANALYTICAL CHEMISTRY 2023年第16期95卷 6620-6628页

作者： Fang, Yanfeng Zhou, Zhixin Hou, Yuhua Wang, Chenchen Cao, xuwen Liu, Songqin Shen, Yanfei zhang, Yuanjian Southeast Univ Sch Chem & Chem Engn Med Sch Jiangsu Engn Lab Smart Carbon Rich Mat & DevicesJ Nanjing 211189 Peoples R China

The development of electrochemiluminescence (ECL) emitters of different colors with high ECL efficiency (0ECL) is appealing yet challenging for ultrasensitive multiplexed bioassays. Herein, we report the synthesis of highly efficient polymeric carbon nitride (CN) films with fine-tuned ECL emission from blue to green (410, 450, 470, and 525 nm) using the precursor crystallization method. More importantly, naked eye observable and significantly enhanced ECL emission was achieved, and the cathodic 0ECL values were ca. 112, 394, 353, and 251 times those of the aqueous Ru(bpy)3Cl2/K2S2O8 reference. Mechanism studies showed that the density of surface-trapped electrons, the associated nonradiative decay pathways, and electron-hole recombination kinetics were crucial factors for the high 0ECL of CN. Based on high 0ECL and different colors of ECL emission, the wavelength-resolved multiplexing ECL biosensor was constructed to simultaneously detect miRNA-21 and miRNA-141 with superior low detection limits of 0.13 fM and 25.17 aM, respectively. This work provides a facile method to synthesize wavelength-resolved ECL emitters based on metal-free CN polymers with high 0ECL for multiplexed bioassays.

关键词： Electrochemiluminescence Biosensor MicroRNA Multiplex Carbon nitride

来源：评论

学校读者我要写书评

暂无评论

Insight into Iron Leaching from an Ascorbate-Oxidase-like Fe-N-C Nanozyme and Oxygen Reduction Selectivity

引用

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2023年第27期62卷 e202302463-e202302463页

作者： Cao, xuwen Zhu, Caixia Hong, Qing Chen, Xinghua Wang, Kaiyuan Shen, Yanfei Liu, Songqin zhang, Yuanjian Southeast Univ Sch Chem & Chem Engn Jiangsu Engn Lab Smart Carbon Rich Mat & Device Jiangsu Prov Hitech Key Lab Biomed Res Nanjing 211189 Peoples R China Southeast Univ Med Sch Nanjing 210009 Peoples R China

Ascorbate (H(2)A) is a well-known antioxidant to protect cellular components from free radical damage and has also emerged as a pro-oxidant in cancer therapies. However, such "contradictory" mechanisms underlying H(2)A oxidation are not well understood. Herein, we report Fe leaching during catalytic H(2)A oxidation using an Fe-N-C nanozyme as a ferritin mimic and its influence on the selectivity of the oxygen reduction reaction (ORR). Owing to the heterogeneity, the Fe-N-x sites in Fe-N-C primarily catalyzed H(2)A oxidation and 4 e(-) ORR via an iron-oxo intermediate. Nonetheless, trace O-2(center dot-) produced by marginal N-C sites through 2 e(-) ORR accumulated and attacked Fe-N-x sites, leading to the linear leakage of unstable Fe ions up to 420 ppb when the H(2)A concentration increased to 2 mM. As a result, a substantial fraction (ca. 40 %) of the N-C sites on Fe-N-C were activated, and a new 2+2 e(-) ORR path was finally enabled, along with Fenton-type H(2)A oxidation. Consequently, after Fe ions diffused into the bulk solution, the ORR at the N-C sites stopped at H2O2 production, which was the origin of the pro-oxidant effect of H(2)A.

关键词： Antioxidants Iron Nanozymes Oxygen Reduction Selectivity Pro-Oxidants

来源：评论

学校读者我要写书评

暂无评论

The Imaging Features and Diagnostic Value of Computerised Tomography in Seminal Duct Tuberculosis

引用

JOURNAL OF MULTIDISCIPLINARY HEALTHCARE 2023年 16卷 1395-1402页

作者： Qi, Min zhang, Le Gan, Wei Xu, Yanling Wei, Jialu Fu, xuwen Li, Xiang Third Peoples Hosp Kunming Yunnan Clin Med Ctr Infect Dis Dept Radiol 319 Wujing St Kunming 650041 Peoples R China Third Peoples Hosp Kunming Yunnan Clin Med Ctr Infect Dis Dept ICU Kunming 650041 Peoples R China

Objective: To analyse the computerised tomography (CT) imaging features and diagnostic value of seminal duct tuberculosis (TB). Methods: The imaging data of male patients with ejaculatory duct TB who underwent surgical treatment in our hospital from 1 January 2019 to 31 December 2019 were retrospectively analysed. Through CT images, seminal duct TB was divided into different types, and the CT image features of different types of TB were analysed. The differences in diagnosis between CT and pathological results were compared. Results: According to the CT manifestations of TB of the intrapelvic segment of seminal duct TB, this disease could be divided into an intra-tubular calcification type, a lumen dilatation and effusion type and a wall thickening type, among which 6 cases (15.8%) were intra-tubular calcification types, 14 cases (36.8%) were lumen dilatation and effusion types and 18 cases (47.4%) were wall thickening types. The diagnostic efficacy of CT in the diagnosis of ejaculatory duct TB: sensitivity = 63.89% (23/36), specificity = 80.01% (44/53), accuracy = 75.28% (67/89), positive predictive value = 51.87% (43/109), negative predictive value = 77.19% (44/57) and kappa = ***: CT has high sensitivity and specificity in the diagnosis of seminal duct TB. The classification of seminal duct TB using CT images is of great significance for the diagnosis and treatment of the disease.

关键词： seminal duct tuberculosis computerised tomography

来源：评论

学校读者我要写书评

暂无评论

Size and Charge Dual-Switchable Nanoparticles for Achieving Chemosensitization and Immune Infiltration against Pancreatic Ductal Adenocarcinoma

引用

ADVANCED FUNCTIONAL MATERIALS 2025年第1期35卷

作者： Song, Haolin Chen, Hongyi Chen, Qinjun Fan, Hongrui Li, Chufeng Wang, Yu zhang, Shilin Li, xuwen Su, Boyu Sun, Tao Jiang, Chen Fudan Univ Sch Pharm Dept Pharmaceut Key Lab Smart Drug DeliveryMinist EducState Key Shanghai 201203 Peoples R China MOE Frontiers Ctr Brain Sci Shanghai 201203 Peoples R China Fujian Med Univ Affiliated Hosp 1 Natl Reg Med Ctr Dept Digest Dis Binhai Campus Fuzhou 350212 Peoples R China

Pancreatic ductal adenocarcinoma (PDAC), one of the most challenging cancers, is uniquely characterized by a biological barrier composed of multiple components in the extracellular matrix, preventing penetration of chemotherapeutic agents and hindering clinical drug treatment. Collagen I arrangement is critical. In this study, gemcitabine is chosen as the chemotherapeutic agent and dasatinib as the collagen-I-disrupting agent. When collagen I arrangement is disrupted, not only the chemotherapeutic drug enters the tumor area better, but the infiltration of CD8+ T cells into the tumor also increases. Therefore, a hypoxia-responsive linker-crosslinked polymer, DGD/L@GBI, is designed, which can be simultaneously loaded with two therapeutic agents, gemcitabine and dasatinib. The polymer is encapsulated by nucleic acid aptamers that target the PDAC stromal microenvironment and shield the surface. The aptamer is removed upon arrival at the PDAC hypoxic microenvironment, exposing the positively charged core to achieve charge reversal. Particle size transformation is achieved using linkers that respond to a hypoxic microenvironment. Increased intratumoral penetration is achieved using the dual transformation capabilities of the formulation. Pairing these two agents can result in a powerful efficacy in chemotherapy sensitization and immune infiltration.

关键词： charge reversal chemosensitization immune infiltration pancreatic ductal adenocarcinoma size reduction

来源：评论

学校读者我要写书评

暂无评论

Graded Error Compensation Method for Heavy-Load Manipulators Based on Laser Tracking Measurement 16th

Graded Error Compensation Method for Heavy-Load Manipulators...

引用

16th International Conference on Intelligent Robotics and Applications, ICIRA 2023

作者： Chen, zhangwei Zu, Hongfei zhang, Xiang Chen, xuwen Wang, Zhirong State Key Laboratory of Fluid Power and Mechatronic Systems Zhejiang University Hangzhou310058 China School of Mechanical Engineering Zhejiang Sci-Tech University Hangzhou310018 China Zhejiang Premax Co. Ltd Ningbo315048 China Testing Standardization and Certification Changzhou Institute of Inspection Changzhou21 3000 China

ISBN: (纸本)9789819964888

In order to meet the high positioning accuracy requirements of industrial application scenarios for manipulators, the motion accuracy of industrial manipulators is generally improved through error compensation. However, due to the presence of non-geometric errors such as friction and joint backlash, error compensation is usually a complex nonlinear problem. Therefore, the existing methods of improving the absolute positioning accuracy of manipulators through model parameter calibration are difficult to obtain good performance, especially for heavy-load manipulators. To solve the above problems, this manuscript proposes a graded error compensation method for heavy-load manipulators based on laser tracking measurement, which realizes the compensation of kinematics error and joint stiffness, and improves the positioning accuracy of the manipulator in the entire workspace. Firstly, the geometric parameters were modeled and compensated by combining the distance model and the Denavit-Hartenberg (DH) model. Then, joint stiffness errors were studied and compensated. Finally, experiments were conducted on a heavy-load manipulator to verify the feasibility and effectiveness of this method. © The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2023.

关键词： Error compensation

来源：评论

学校读者我要写书评

暂无评论

A Compact Optically Pumped Cesium Beam Clock with a Differential Detection Scheme 37

A Compact Optically Pumped Cesium Beam Clock with a Differen...

引用

37th European Frequency and Time Forum, EFTF 2024

作者： Li, Chao Sun, Fuyu Hu, xuwen Liu, Jie Li, Xiaofeng zhang, Shougang National Time Service Center Chinese Academy of Sciences Xi'an China Chinese Academy of Sciences Key Laboratory of Time Reference and Applications Xi'an China

ISBN: (纸本)9798350354270

Compact optically pumped cesium beam clocks have become a focus in cesium clock research due to their high atomic utilization and excellent short-term frequency stability. However, stray light noise, one of the main noise sources, limits the stability improvement. In this paper, we present a compact optically pumped cesium clock that uses differential detection to reduce the impact of stray light on clock performance. It incorporates an additional fluorescence collector to capture stray light during detection and subtract it from the clock transition signal, effectively reducing stray light level. Consequently, this scheme significantly enhances the signal-to-noise ratio, improving the short-term frequency stability of the compact optically pumped cesium clock. © 2024 IEEE.

关键词： Frequency stability

来源：评论

学校读者我要写书评

暂无评论

Impermeability performance and corrosion resistance mechanism of basalt fiber recycled concrete under the coastal tidal environment

引用

CONSTRUCTION AND BUILDING MATERIALS 2024年 411卷

作者： Yang, Wenrui Huang, Yuewen Tang, Zhiyi Xiong, Xiaolong Li, Chengwei Zhong, xuwen Liu, Liai Zhou, Hai zhang, Xun East China Univ Technol Sch Civil & Architectural Engn Nanchang 330012 Peoples R China Wuhan Univ Technol Sch Transportat & Logist Engn Wuhan 430063 Peoples R China

The application of Recycled Aggregate Concrete (RAC) can effectively reduce resource consumption and mitigate environmental pollution. Under the coastal tidal environments, the performance of concrete is significantly impacted by environmental degradation. Incorporating fibers into RAC can enhance its performance in such special conditions. This study investigates the variations in properties of RAC with different Basalt Fiber (BF) volume ratios (0%, 0.5%, 1.0%, 1.5%) under composite salt dry-wet cyclic erosion cycles (0 d, 30 d, 60 d, 90 d). The results from apparent corrosion morphology analysis, internal microstructure examination, and impermeability testing demonstrate that BF can effectively inhibit the expansion of micro cracks and micropores within the test block while improving the overall compactness of the internal structure of RAC. When the BF content reaches 1.0%, it exhibits an optimal toughening effect on RAC with significantly improved impermeability and corrosion resistance properties. Furthermore, this paper comprehensively summarizes and verifies the corrosion damage mechanism of Basalt Fiber Recycled Aggregate Concrete (BFRAC) under composite salt dry-wet cycles through chemical reaction principles. A salt solution erosion model for BFRAC is proposed to elucidate fiber crack resistance mechanisms and explain accelerated corrosion caused by ion crack channels within salt solutions. This proposed model provides theoretical support for understanding salt erosion damage in fiberreinforced concrete.

关键词： Coastal tidal environment Basalt fiber Recycled concrete Impermeability Corrosion mechanism

来源：评论

学校读者我要写书评

暂无评论

Research on sound source localization based on sound sensor 4

Research on sound source localization based on sound sensor

引用

4rth International Conference on Applied Mathematics, Modelling, and Intelligent Computing, CAMMIC 2024

作者： Jin, Hailei Wang, xuwen Huang, Kun Xiong, Xiaomin zhang, Minshu Li, Jiang Xinyu Power Supply Branch of State Grid jiangxi Power Co. Ltd. Xinyu338000 China Shanghai University of Electric Power Shanghai200090 China

ISBN: (纸本)9781510681637

Nowadays, most of the 10 kV distribution network cable lines are laid underground in the form of direct burial or casing, and the cable is cut off by the construction machinery, resulting in the accident of line tripping. In the construction of urban construction, third-party external forces such as manual excavation, mechanical excavation and illegal invasion will cause serious damage to underground cables. Therefore, it is of great engineering application value to develop cable marking piles with sound source localization function and find the location of damage points in time. In order to improve the accuracy and effectiveness of positioning, but also to achieve rapid positioning of the source of damage, this paper is based on the sound sensor, using its flexibility, efficiency and timeliness, by controlling the number and location of the sound sensor, combined with the sound intensity to locate the sound source. At the same time, the sound sensor is connected with the number and position of the marking pile, and the traditional cable marking pile is improved to accurately locate the damage source in time. © 2024 SPIE.

关键词： Excavation

来源：评论

学校读者我要写书评

暂无评论

Vibration-induced emission: Dynamic multiple intrinsic luminescence

引用

COORDINATION CHEMISTRY REVIEWS 2022年 472卷

作者： zhang, Zhiyun Jin, Xin Sun, xuwen Su, Jianhua Qu, Da -Hui East China Univ Sci & Technol Frontiers Ctr Materiobiol & Dynam Chem Sch Chem & Mol Engn Key Lab Adv Mat 130 Meilong Rd Shanghai 200237 Peoples R China East China Univ Sci & Technol Feringa Nobel Prize Scientist Joint Res Ctr Frontiers Ctr Materiobiol & Dynam Chem Sch Chem & Mol Engn 130 Meilong Rd Shanghai 200237 Peoples R China

pi-Conjugated molecules exhibit prosperous excited-state processes and tunable luminescence proper-ties, as the key building blocks for fabricating smart luminescent materials. In this review, we focus on the vibration-induced emission (VIE) of saddle-shaped dihydrophenazine (DHP) derivatives, which involves dynamic conformation changes of photoexcited molecules to planar configuration in charge of the large Stokes-shifted emission. By modifying the rigid-flexible fused skeleton of DHP, a continuously tunable emission over a wide range can be achieved through the dynamic bent-to-planar transformations of a single-molecule entity. The interplay of aromaticity and steric hindrance was proposed as the regu-lation mechanism, and applied to clarify how the luminescence characteristics were affected by the intramolecular steric hindrance and ring tension. By taking advantage of the VIE phenomenon, i.e., dra-matic structural/electronic responses and sensitive vibration-degree-dependent emissions, donor -bridge-acceptor systems with conformation-dependent electron/energy donors were fabricated, and the output of colorful fluorescent signals visible to the naked eye were realized in response to minor inter-/intra-molecular stimulations. Furthermore, the VIE phenomenon of DHPs brings new possibilities for obtaining different conductance features as one molecule changes its conformation in the metal- molecule-metal junction arrangement. This review includes the recent progress in VIE research as well as our perspectives on future directions.(c) 2022 Elsevier B.V. All rights reserved.

关键词： Dihydrophenazine Vibration-induced emission Luminescence-structure relationships Dynamic multiple emission Photoconductance

来源：评论

学校读者我要写书评

暂无评论

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案：

请选择收藏分类：

通借通还

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：