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Modeling and Analysis of the Reliability of Machining Process of Diesel Engine Blocks Based on PFMECA

IEEE ACCESS 2019年 7卷 124759-124773页

作者： Tian, Guizhong zhang, Wei Ma, Zhengyu Zhou, Honggen Jing, xuwen Li, Guochao Jiangsu Univ Sci & Technol Sch Mech Engn Zhenjiang 212003 Jiangsu Peoples R China Jiangsu Univ Sci & Technol Jiangsu Prov Key Lab Adv Mfg Marine Mech Equipmen Zhenjiang 212003 Jiangsu Peoples R China

Due to its difficulty in maintenance, the diesel engine have special requirements on process reliability of the engine block, which is one of the most important and hard-to-machining components of the engine, and will directly affects the performance and service life of the engine. With continuous improvements to the engine quality, the process reliability of the engine block have become more and more important. However, the previous researches mainly focus on the reliability of products, machine tools, or cutting tools, while the researches on the reliability of machining process, which lead to unstable quality of the machined engine block, have been little discussed. Therefore, this paper proposes an integrated method to analyze the process reliability of DEB (Diesel Engine Blocks). First, the reliability model of the DEB machining process is established by using reliability block diagram method. The model is mainly concerned with the process reliability and error-free judgment probability of the key features of DEB, which is deduced by using the PFMECA (Process Failure Mode, Effects and Criticality Analysis) method. Then, the response surface and FEM method is used to establish a mathematical model for the key features and its key influencing factors, and the process reliability of the key features is evaluated by Monte Carlo simulation. The reliability of the machining process is evaluated by substituting the process reliability of the key features into the reliability model of the DEB machining process. The method is applied to evaluate the reliability of the machining process of a certain type of DEB and solves the problem that the actual machining data are insufficient for reliability evaluation.

关键词： Process reliability PFMECA FEM Monte Carlo simulation

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Occurrence, fate and impact of steroidal estrogens and xenoestrogens in plants: A review

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Journal of Environmental Management 2025年 389卷 126194页

作者： Junyue Wang Yang Chen Zikang zhang Jiayi Yan Wanting Ling xuwen Chen Yanzheng Gao Institute of Organic Contaminant Control and Soil Remediation College of Resources and Environmental Sciences Nanjing Agricultural University Nanjing 210095 China

Estrogens encompass both steroidal estrogens and xenoestrogens. Natural steroidal estrogens, as hormones secreted by animals, regulate physiological activities within organisms. Synthetic steroidal estrogens and xenoestrogens are also widely utilized as pharmaceutical agents and industrial materials. Globally, due to the incomplete reduction of estrogens during the aerobic composting process, most commercially available manure-based fertilizers contain residual estrogens. The application of these fertilizers and wastewater irrigation lead to the migration of estrogens into agricultural soil. Exposure to estrogen concentrations exceeding safety levels can severely disrupt the reproductive, nervous, and endocrine systems. As emerging contaminants, it is imperative to in investigate the behavior of estrogen in any environment. As part of the agricultural system, plants influence the fate of estrogens in farm field through uptake and accumulation, especially in vegetables and crops closely related to human health. The transport and translocation of estrogens throughout the entire growth cycle of plants relate to the flow of estrogens in ecosystems and biological threats. Therefore, it is urgent to elucidate the mechanisms by which plants uptake, transport, and translocation estrogens. Additionally, the impact of estrogens on plant physiology and biochemistry is worth investigating. Unlike other pollutants, the effect of estrogens on plant growth is dose-dependent. Therefore, while addressing estrogen pollution, Finally, this paper proposes some new future research needs for estrogens in plants.

关键词： Dose-dependent effects Growth and development Phytotoxicity Plant uptake Steroidal estrogens Xenoestrogens

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Effect of Pre-Coagulation on Catalytic Ozonation in the Tertiary Treatment of Coking Wastewater: Kinetic and Ozone Consumption Analysis

SSRN

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SSRN 2022年

作者： Wang, Hao zhang, Siyu He, Can Yuan, Run Wu, Xu Guo, Shaoqing He, xuwen Van Hulle, Stijn W.H. Beijing100083 China LIWET Department of Green Chemistry and Technology Ghent University Campus Kortrijk Graaf Karel De Goedelaan 5 KortrijkB-8500 Belgium KU Leuven Department of Chemical Engineering PET Lab J. De Nayerlaan 5 Sint-Katelijne-WaverB-2860 Belgium

The ozone-based advanced oxidation process in wastewater effluent degrades refractory organics efficiently and significantly. Nevertheless, high energy consumption is a challenge that hinders its widespread application. In this work, the pre-coagulation enhanced catalytic ozonation process for the treatment of biologically treated coking wastewater (BTCW) was investigated. The chemical oxygen demand (COD) removal results indicated that catalytic ozonation has an inadequate removal effect on the organic pollutants in BTCW. Moreover, the two-stage degradation occurred in the COD ozonation process, of which the slow reaction rate in the second stage was the main reason that limited its overall effect. The pre-coagulation overcame the obstacle of the limited effect of catalytic ozonation treatment of BTCW because of its ability to remove hydrophobic organics. The combination of pre-coagulation and catalytic ozonation was significantly beneficial for reducing the COD content in BTCW and increased the COD removal of BTCW from 45% to 69%. There was a linear relationship between specific ozone consumption and ozone dosage regardless of whether BTCW was subjected to pre-coagulation. The fact that the slope of this linear relationship with pre-coagulation was much smaller than that without pre-coagulation. It indicates that pre-coagulation could significantly reduce ozone consumption. The primary role of pre-coagulation was to reduce ozone consumption considerably in the second stage of the ozonation process. The ozone consumption per unit mass of COD in the second stage reached 24.3 gO 3 /gCOD without pre-coagulation, while that was only 6.8 gO 3 /gCOD with pre-coagulation. © 2022, The Authors. All rights reserved.

关键词： Chemical oxygen demand

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Investigation of energetic ion losses induced by long-lived saturated internal mode with energetic particle diagnostics in the HL-2A tokamak

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NUCLEAR FUSION 2023年第8期63卷 086014-086014页

作者： zhang, Jie zhang, Yipo Chen, Wei Cheng, Shikui Ogawa, Kunihiro He, Xiaofei Wang, Yongqin Liu, Yi Xu, Min Isobe, Mitsutaka Zhu, Yuxuan Zhan, xuwen Zhou, Jianhang zhang, Jinglong Liu, Liang He, Xiaoxue Li, Dong Li, Yonggao Guo, Wenping Yu, Liming Hao, Guangzhou Li, Bo Shi, Zhongbing Ji, Xiaoquan Zhong, Wulv Southwestern Inst Phys POB 432 Chengdu 610041 Peoples R China Natl Inst Fus Sci Natl Inst Nat Sci Toki Japan SOKENDAI Grad Univ Adv Studies Toki Japan Chengdu Univ Technol Coll Nucl Technol & Automation Engn Chengdu 610059 Peoples R China

Several sets of energetic particle diagnostics, including a set of neutron flux monitoring systems, a solid-state neutral particle analyzer and a fast ion loss probe (FILP), have been used to investigate the energetic ion losses induced by the long-lived saturated internal mode (LLM) in the HL-2A tokamak. Clear experimental evidence for different levels of energetic ion losses induced by LLM, sawtooth and minor disruption has been observed. A numerical calculation for the evolution of neutron emissions was carried out with the FBURN code, and it shows that the neutron emission drop rate linearly increases with the LLM amplitude and no threshold perturbation amplitude exists, illustrating that the loss mechanism for LLM induced energetic ion loss is dominantly convective. In addition, measurement results of the FILP demonstrate that LLM tends to expel energetic ions with relatively low energy (E < 27 keV) and high pitch angle (? > 60(?)), and can suppress the prompt loss of energetic ions with high energy and low pitch angle to a certain degree. Furthermore, the physical process for LLM induced energetic ion loss can be explained by orbit calculations, which show that LLM induced lost energetic ions will transport from center to peripheral region first, and then get lost out of plasma. The experimental observations are successfully reproduced by calculations using the ORBIT code combined with both the NUBEAM code and the MARS-K code. The paper clearly describes the whole physical process of LLM induced energetic ion loss for the first time in the HL-2A tokamak.

关键词： energetic ion loss long-lived saturated internal mode neutron flux measurement neutral particle analyzer fast ion loss probe

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全肠无神经节细胞症合并新的 SOX10突变1例

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临床小儿外科杂志 2025年第4期24卷 386-388页

作者：张骜戴春娟赵绪稳王金虎杜晓斌杨福江胡博天津市儿童医院新生儿外科天津

全肠无神经节细胞症是先天性巨结肠中十分罕见的类型, 其临床表现不典型, 诊疗上存在一定困难。SOX10基因突变被认为与先天性巨结肠症有关。本文报道1例合并新的SOX10突变的全肠无神经节细胞症患儿, 以提高临床对此罕见疾病的认识。

关键词：先天性巨结肠全肠无神经节细胞症 SOX10

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一例仔猪蓝耳病毒与细菌混合感染的诊治

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现代牧业 2024年第3期8卷 29-33页

作者：鲁绪文谭伟明张寄香王贵平湖南农业大学动物医学院湖南长沙410128 益阳职业技术学院湖南益阳413000

湖南省益阳市某养猪场仔猪出现发烧、呼吸急促以及咳嗽等临床症状。经剖检,发现病猪出现腹股沟淋巴结肿大和肺水肿等病变。为尽快对仔猪所患疾病进行确诊以便采取有效的防治措施,采集病猪的肺、肝、肾和肠系膜淋巴结,进行猪蓝耳病毒、... 详细信息

湖南省益阳市某养猪场仔猪出现发烧、呼吸急促以及咳嗽等临床症状。经剖检,发现病猪出现腹股沟淋巴结肿大和肺水肿等病变。为尽快对仔猪所患疾病进行确诊以便采取有效的防治措施,采集病猪的肺、肝、肾和肠系膜淋巴结,进行猪蓝耳病毒、猪圆环病毒(2型)、奇异变形杆菌、粪肠球菌及大肠杆菌的qPCR检测、细菌分离培养鉴定及药敏试验。结果显示,样品的猪蓝耳病毒qPCR检测为阳性,猪圆环病毒(2型)为阴性。病原菌的分离鉴定及药敏试验结果表明,分离得到奇异变形杆菌、粪肠球菌及大肠杆菌三株致病菌;三种菌均对多粘菌素B、呋喃唑酮和万古霉素敏感。本次病例检测结果说明,仔猪是在感染猪蓝耳病毒后继发感染多种细菌引起疾病的,防控首选药物为多粘菌素B、呋喃唑酮或万古霉素,猪场应加强疫苗免疫工作。本研究为该场仔猪细菌性呼吸道感染的防控提供理论基础。

关键词：断奶仔猪蓝耳病毒药敏试验继发感染

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A Computational Framework Towards Medical Image Explanation 7th

A Computational Framework Towards Medical Image Explanation

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AIME 7th Joint International Workshop on Knowledge Representation for Health Care and Process-Oriented Information Systems in Health Care (KR4HC/ProHealth) / 1st Workshop on Transparent, Explainable and Affective AI in Medical Systems (TEAAM)

作者： Wang, xuwen zhang, Yu Guo, Zhen Li, Jiao Chinese Acad Med Sci & Peking Union Med Coll Inst Med Informat & Lib Beijing 100020 Peoples R China Genertec Universal Med Grp Co Ltd Beijing 100000 Peoples R China

ISBN: (纸本)9783030374464;9783030374457

In this paper, a unified computational framework towards medical image explanation is proposed to promote the ability of computers on understanding and interpreting medical images. Four complementary modules are included, such as the construction of Medical Image-Text Joint Embedding (MITE) based on large-scale medical images and related texts;a Medical Image Semantic Association (MISA) mechanism based on the MITE multimodal knowledge representation;a Hierarchical Medical Image Caption (HMIC) module that is visually understandable to radiologists;and a language-independent medical imaging report generation prototype system by integrating the HMIC and transfer learning method. As an initial study of automatic medical image explanation, preliminary experiments were carried out to verify the feasibility of the proposed framework, including the extraction of large scale medical image-text pairs, semantic concept detection from medical images, and automatic medical imaging reports generation. However, there is still a great challenge to produce medical image interpretations clinically usable, and further research is needed to empower machines explaining medical images like a human being.

关键词： Medical image explanation Medical Image-Text Joint Embedding Medical Image Semantic Association Hierarchical Medical Image Caption Medical imaging reports generation

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艾滋病合并肠道马尔尼菲篮状菌感染1例

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传染病信息 2024年第4期37卷 381-384页

作者：李翔陈海云付旭文李海雯张乐昆明市第三人民医院/云南省传染性疾病临床医学中心 650041

小肠出血是较为常见的临床问题,且诊断具有一定的挑战性。本文报道了1例艾滋病合并肠道马尔尼菲篮状菌感染患者,表现为发热、腹痛、血便,CT提示空肠上段活动性出血,内镜提示空肠上段黏膜病变,血培养及内镜下活检提示马尔尼菲蓝状菌感染... 详细信息

小肠出血是较为常见的临床问题,且诊断具有一定的挑战性。本文报道了1例艾滋病合并肠道马尔尼菲篮状菌感染患者,表现为发热、腹痛、血便,CT提示空肠上段活动性出血,内镜提示空肠上段黏膜病变,血培养及内镜下活检提示马尔尼菲蓝状菌感染,行抗真菌治疗后,病情好转。这提示马尔尼菲蓝状菌可感染肠道,引起肠道出血等并发症,应用多种检查方法积极寻找出血部位,诊断明确后有效的抗真菌治疗,可取得良好疗效。

关键词：获得性免疫缺陷综合征马尔尼菲篮状菌真菌病空肠疾病

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Treatment of coking wastewater using oxic-anoxic-oxic process followed by coagulation and ozonation

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Carbon Resources Conversion 2019年第2期2卷 151-156页

作者： Jianbing Wang Yuxian Ji Fengyuan zhang Dongliang Wang xuwen He Chunrong Wang School of Chemical and Environmental Engineering China University of Mining and Technology-BeijingBeijing 100083China

An oxic-anoxic-oxic(O-A-O)system followed by coagulation and ozonation processes was used to study the treatment of coking *** the O-A-O process,the removals of NH4+-N,total nitrogen and COD were 91.5-93.3%,91.3-92.6%and 89.1-93.8%,respectively when employing hydraulic residence times of 60 h for the biochemical *** removal of NH4+-N was obtained due to the placement of an aerobic tank in front of A-O system which can mitigate the inhibitory effect of toxic compounds in coking wastewater on nitrifying *** of methanol into the anoxic reactor greatly increased the removal of total nitrogen,indicating that denitrifiers can hardly use organic compounds in coking wastewater as carbon source for *** values of the effluent from the O-A-O system were still higher than 260 mg/L even with a prolonged time of 160 h mainly due to the high refractory properties of residual compounds in the *** subsequent coagulation and ozonation processes resulted in the COD removal of 91.5%-93.3%and reduced the relative abundance of large molecular weight(MW)organics(>1 kDa)from 55.8%to 20.93%with the ozone,PAC and PAM dosages of 100,150 and 4 mg/L *** these conditions,the COD value and concentration of polycyclic aromatic hydrocarbons in the final effluent were less than 80 and 0.05 mg/L,respectively,which meet the requirement of the Chinese emission *** results indicate that the combined technology of O-A-O process,coagulation and ozonation is a reliable way for the treatment of coking wastewater.

关键词： Coking wastewater Activated sludge process Coagulation Ozonation Nitrification-denitrification

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Medical Image Labelling and Semantic Understanding for Clinical Applications 1

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10th International Conference of the CLEF-Association (CLEF)

作者： Wang, xuwen Guo, Zhen zhang, Yu Li, Jiao Chinese Acad Med Sci & Peking Union Med Coll Inst Med Informat Med Lib Beijing 100020 Peoples R China

ISBN: (数字)9783030285777

ISBN: (纸本)9783030285777;9783030285760

Semantic concept detection contributes to machine understanding and learning from medical images;it also plays an important role in image reading and image-assisted diagnosis. In this study, the problem of detecting high-frequency concepts from medical images was transformed into a multilabel classification task. The transfer learning method based on convolutional neural networks (CNNs) was used to recognize high-frequency medical concepts. The image retrieval-based topic modelling method was used to obtain the semantically related concepts from images similar to the given medical images. Our group participated in the concept detection subtasks that were launched by ImageCLEFcaption 2018 and ImageCLEFmed Caption 2019. In the 2018 task, the CNN-based transfer learning method achieved an F1 score of 0.0928, while the retrieval-based topic model achieved an F1 score of 0.0907. Although the latter method recalled some low-frequency concepts, it heavily depended on the image retrieval results. For the latter 2019 task, we proposed body part-based pre-classification strategies and achieved an F1 score of 0.2235. The results indicated that the transfer learning-based multi-label classification method was more robust in high-frequency concept detection across different data sets, but there is still much room for improvement in large-scale open semantic concept detection research.

关键词： Concept detection Transfer learning Multi-label classification Pre-classification Medical image retrieval

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