In Ref.[1],Eq.(8)has a typo,the following replacement should be done.γ_(bb)/2rδ/δr(rδ(r,t)/δr=2γ_(bb)/R_(bb)-Þ(t,t)-Ⅱ[h[r,t)](bubble=drop-bubble=drop)The publisher regrets an error in the original–article...
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In Ref.[1],Eq.(8)has a typo,the following replacement should be done.γ_(bb)/2rδ/δr(rδ(r,t)/δr=2γ_(bb)/R_(bb)-Þ(t,t)-Ⅱ[h[r,t)](bubble=drop-bubble=drop)The publisher regrets an error in the original–article,and the sentence that explained the equation“Eqs.(8)–(10)show the augmented Young–Laplace equation for the interactions of gas bubbles or liquid droplets in different configurations,where Rb is the bubble/drop radius,Rp is the particle radius,Rbp=(1/Rb+1/Rp)1.
Background: Recent studies have elucidated the instrumental role of microRNAs (miRNAs) in neuropathic pain (NP) progression. As one member of miRNAs, miR-130a-3p has been proved as a mediator in inflammation and neuro...
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Background: Recent studies have elucidated the instrumental role of microRNAs (miRNAs) in neuropathic pain (NP) progression. As one member of miRNAs, miR-130a-3p has been proved as a mediator in inflammation and neuronal maturation. The present study attempted to elucidate what effect miR-130a-3p exerts on NP. Materials and methods: The miR-130a-3p expression in the spinal cord tissues of rat with spinal cord compression injury (SCI) and LPS-induced BV2 microglia was determined with RT-PCR, which was further applied to analyze the clinical relevance between miR-130a-3p and neuropathic pain. Besides, the expression of IGF-1, IL-1 beta, IL-6, and TNF-alpha in the spinal cord tissues of rats was measured using RT-PCR and ELISA after intrathecal injection of miR-130a-3p inhibitors and tail vein injection of IGF-1 low-expression lentivirus (Lv-shIGF-1). Further, neuronal apoptosis (labeled by Caspase3) and microglial activation (labeled by Iba1) were examined by immunohistochemistry (IHC), and the levels of IGF-1, IGF-1R, NF-kappa B were determined by western blot. Additionally, bioinformatic was employed to analyze the potential target genes of miR-130a-3p. Furthermore, the dual luciferase activity assay and RNA immunoprecipitation assay were conducted to further substantiate whether miR-130a-3p targets IGF-1. Results: In comparison with the sham group, the miR-130a-3p expression was remarkably up-regulated in the spinal cord lesions of SCI rats. The ELISA results showed that inhibiting the miR-130a-3p significantly reduced NP symptoms of SCI rats, mitigated neuronal apoptosis, microglial activation, repressed NF-kappa B phosphorylation and the IL-1 beta, IL-6 and TNF-alpha expressions in SCI rats. Contrarily, downregulation of miR-130a-3p increased IGF-1 and IGF-1R expression. What's more, we observed the same effects in BV2 microglia. In addition, the bioinformatics analysis showed that miR-130-3p targeted at the 3'-untranslated region of IGF-1 and inhibiting its expr
Following the 2011 Fukushima Daiichi nuclear catastrophe, there has been a significant surge in interest towards innovative materials capable of enhancing the safety, performance, and efficiency of nuclear reactors. T...
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Following the 2011 Fukushima Daiichi nuclear catastrophe, there has been a significant surge in interest towards innovative materials capable of enhancing the safety, performance, and efficiency of nuclear reactors. This study introduces a new class of layered ternary compounds, specifically (UC)nSi3C2 (n = 1,2), and derived twodimensional (2D) U2C, discovered through first-principles calculations. We predict the electronic, mechanical, and thermodynamic properties of these compounds within the PBE and PBE + U frameworks, with a comparative analysis of the (UC)nAl3C2 (n = 1,2) series. Our findings reveal that the USi3C3 and U2Si3C4 compounds exhibit mechanical and dynamic stabilities, suggesting their potential for experimental synthesis under specific conditions. These compounds demonstrate superior mechanical and thermal properties as nuclear fuels, including higher elastic moduli and improved ductility compared to (UC)nAl3C2 compounds. The mechanical and dynamical stabilities of 2D U2C are confirmed, and the calculated thermal conductivity and mechanical properties position it as a promising candidate for high-performance nuclear fuel applications. We anticipate that the present work will bolster future experimental endeavors and help explore the practical applications of these novel materials in future nuclear systems.
Concentrating optical field in an eigenmode with a tiny volume is vitally important for light-matter interactions at the fundamental level and underpins new technologies. In the past decades, researchers have investig...
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Gas bubbles widely exist in nature and numerous industrial processes. The physicochemical characteristics of bubbles such as large specific surface area, low density, and hydrophobicity make them an ideal platform for...
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Gas bubbles widely exist in nature and numerous industrial processes. The physicochemical characteristics of bubbles such as large specific surface area, low density, and hydrophobicity make them an ideal platform for developing colloidal and interfacial technologies. Over the past few decades, much effort has been devoted to investigating the properties and behaviors of bubbles and their applications. A series of bubble-based technologies (BBTs) have been developed, which have attracted increasing attention and shown great importance in a wide range of engineering, material, and biological fields. These BBTs, such as bubble flotation and the bubble-liposome system, provide feasible and promising solutions to mineral separation, material assembling, medical diagnosis, and drug delivery. In this work, we have systematically reviewed the physicochemical characteristics of bubbles and how to modulate their behaviors in complex fluid systems, as well as the underlying fundamental interaction mechanisms of bubbles in related BBTs. Advanced nanomechanical techniques such as atomic force microscopy, which are used to quantify the interaction mechanisms in bubble-containing systems, have been introduced. The effects of various influential factors on the bubble behaviors are discussed, which provide potential approaches to improve the controllability and performance of BBTs. The recent advances in the applications of selected BBTs in engineering, biomedical, and material areas are presented. Some remaining challenging issues and perspectives for future studies have also been discussed. This review improves the fundamental understanding of characteristics and surface interaction mechanisms of bubbles, with useful implications for developing advanced BBTs.
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