Background: Finger blood volume pulse (F-BVP) contains abundant human cardiovascular system information, including information regarding circulation in the heart, blood vessel function, and the microcirculation system...
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Background: Finger blood volume pulse (F-BVP) contains abundant human cardiovascular system information, including information regarding circulation in the heart, blood vessel function, and the microcirculation system. Pulse waveform analysis is a method for analyzing F-BVP. Methods and results: A new parameter of F-BVP, called waveform index (WI), was extracted, defined, subsequently compared between groups of different cardiovascular function, and compared with age and systolic blood pressure. WI values of the negative and positive groups were 0.209 +/- 0.066 (p<.001) and 0.305 +/- 0.066 (p<.001), respectively. The classification threshold value of WI was 0.24, revealing a sensitivity of 77%, a specificity of 68% and a classification accuracy of 73%. The odds ratio (OR) was 7.164, indicating that subjects with WI > 0.24 had a 7.164 times greater risk of suffering from cardiovascular disease than of not suffering from cardiovascular disease. Age and systolic blood pressure had consistent correlation with WI, in addition, WI had the same trend with age and systolic blood pressure. Conclusion: Because WI of F-BVP was determined according to only F-BVP waveform and increases in age and systolic blood pressure, different values of WI represent different cardiovascular physiological conditions. To a certain extent, the changes of WI reflect the changes of human cardiovascular function. Therefore, WI has the potential to be widely used in disease screening and clinical practice.
Ecosystem changes of the coastal areas of the East China Sea (ECS) during the past 30 years have been characterized by increased productivity and increased occurrences of dinoflagellate red tides;both were commonly at...
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Ecosystem changes of the coastal areas of the East China Sea (ECS) during the past 30 years have been characterized by increased productivity and increased occurrences of dinoflagellate red tides;both were commonly attributed to be caused by anthropogenic input of nutrients. However, climate-driven regime shifts were found in the Pacific, but they have not been observed in the ECS owing to the lack of continuous high resolution data. Hence, it is still a challenge to distinguish the influences of anthropogenic activities and climate changes on ECS shelf ecosystem. We compare phytoplankton biomarker (brassicasterol, dinosterol, and alkenones) data of five box cores from the coastal area of the ECS, which afford phytoplankton productivity and community structure records at decadal-scale resolution for the last 100 years. Phytoplankton productivity in all cores increased during the past 50 years, but community structure changes showed different trends. Relative diatom contribution revealed a decreasing trend during the past ca. 50 years in cores DH5-1 and CJ43 collected near the Changjiang Estuary, which were likely caused by increased N/Si and N/P ratios, providing conditions more favorable for dinoflagellates growth. In contrast, the relative diatom contribution increased in cores 32, 34, and DH6-3 further away and south of the Changjiang Estuary, suggesting limited influence of the Changjiang water. Instead, diatom increasing trend is likely caused by increased supply of phosphorus and silicate, as a result of larger Kuroshio intrusion flux and the corresponding strengthened coastal upwelling. Therefore, both anthropogenic activities and climate-driven coastal upwelling have contributed to increased productivities, but these two forcing mechanisms have resulted in contrasting community structure changes at different sites in the coastal area of the ECS.
This paper presents a low power multi-channel chirp-UWB (C-UWB) transmitter for short range communication systems. The C-UWB transmitter generates a wideband FM signal with a steep spectral roll-off, while enabling a ...
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Syndrome wind-cold-dampness in traditional Chinese medicine (TCM) can be referred to diseases of osteoarthritis, rheumatoid arthritis, cervical spondylitis, and spondylitis and so on. Over thousand years TCM clinical ...
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ISBN:
(纸本)9781509040933
Syndrome wind-cold-dampness in traditional Chinese medicine (TCM) can be referred to diseases of osteoarthritis, rheumatoid arthritis, cervical spondylitis, and spondylitis and so on. Over thousand years TCM clinical explorations, this syndrome can be treated with a group of herbal medicines in TCM. However, their molecular level biological functions are still not clear. In this study, a set of algorithms e.g., hypergeometric distribution, Jaccard index, and recursive programming for hierarchy network were deployed in the context gene/protein functional similarity and enrichment analysis. The analysis was mainly focused on the associated herbal medicines, their chemical compounds, target proteins' similarity, and gene ontology terms' hierarchical network overrepresentation through the enrichment analysis of hypergeometric distribution with P-value set to 0.05. As a result, these associated herbs share low level (<0.5) of therapeutic similarities on target proteins, yet with common biological functions for TCM syndrome wind-cold-dampness e.g., signal transduction, transportation, chemical homeostatic and metabolic process.
Dual-band electrochromic composite materials are of utmost importance in advancing the electrochromic field toward achieving the ideal smart window with independent control over visible and near-infrared (NIR) radiati...
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Dual-band electrochromic composite materials are of utmost importance in advancing the electrochromic field toward achieving the ideal smart window with independent control over visible and near-infrared (NIR) radiation. However, such composites usually need deliberate architecting of their mesoscale structure (e.g., via block copolymer-templating method) to make the electrolyte contact with both NIR and visible-light modulating components. Herein, instead of arduously making exterior pores, the intrinsic structural tunnels are utilized directly in electrochromic materials to facilitate the accommodation and transportation of insertion ions, which permit the infiltration of the electrolyte to be in contact with both visible (Prussian blue) and NIR-light modulating components (nonstoichiometric tungsten oxide). Such simple-fabricated composite materials exhibit excellent dual-band electrochromic performance with an unprecedented dynamic optical range for modulation of visible and NIR light, up to 71.2% at 633 nm and 64.8% at 1600 nm, respectively.
Non-invasive measurement of uterine activity using electrohysterogram (EHG) surface electrodes has been attempted to monitor uterine contraction. This study aimed to computationally compare the performance of acquirin...
Non-invasive measurement of uterine activity using electrohysterogram (EHG) surface electrodes has been attempted to monitor uterine contraction. This study aimed to computationally compare the performance of acquiring EHG signals using monopolar electrode and three types of Laplacian concentric ring electrodes (bipolar, quasi-bipolar and tri-polar). With the implementation of dipole band model and abdomen model, the performances of four electrodes in terms of the local sensitivity were quantified by potential attenuation. Furthermore, the effects of fat and muscle thickness on potential attenuation were evaluated using the bipolar and tri-polar electrodes with different radius. The results showed that all the four types of electrodes detected the simulated EHG signals with consistency. That the bipolar and tri-polar electrodes had greater attenuations than the others, and the shorter distance between the origin and location of dipole band at 20 dB attenuation, indicating that they had relatively better local sensitivity. In addition, ANOVA analysis showed that, for all the electrodes with different outer ring radius, the effects of fat and muscle on potential attenuation were significant (all p < 0.01). It is therefore concluded that the bipolar and tri-polar electrodes had higher local sensitivity than the others, indicating that they can be applied to detect EHG effectively.
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