Chunk decomposition is defined as a cognitive process which breaks up familiar items into several parts to reorganize them in an alternative *** present study investigated the effective connectivity of visual streams ...
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Chunk decomposition is defined as a cognitive process which breaks up familiar items into several parts to reorganize them in an alternative *** present study investigated the effective connectivity of visual streams in chunk decomposition through dynamic causal modeling(DCM).The results revealed that chunk familiarity and perceptual tightness made a combined contribution to highlight not only the "what" and the "where" streams,but also the effective connectivity from the left inferior temporal gyrus to the left superior parietal lobule.
Aim: Resilience refers to positive adaption in the face of stress or trauma. Assessing resilience is crucial in trauma-related research and practice. The 10-item Connor-Davidson Resilience Scale (CD-RISC) has been dem...
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Aim: Resilience refers to positive adaption in the face of stress or trauma. Assessing resilience is crucial in trauma-related research and practice. The 10-item Connor-Davidson Resilience Scale (CD-RISC) has been demonstrated to be a valid and reliable tool to achieve this goal. This study was designed to examine the psychometric properties of the 10-item CD-RISC in a sample of Chinese earthquake victims. Methods: A total of 341 participants (185 women, 156 men) aged 20-63 years were recruited from a psychological relief program supported by the Institute of Psychology, Chinese Academy of Sciences following the 'Wenchuan' earthquake. The participants were given the 10-item CD-RISC and the 17-item post-traumatic stress disorder (PTSD) subscale of the Los Angeles Symptom Checklist (LASC) 4 months after the earthquake. Results: The results of exploratory factor analysis indicated that a single-factor model consistent with the original design of the 10-item CD-RISC was support. The scale was also demonstrated to have good internal consistency (Cronbach's alpha = 0.91) and test-retest reliability (r = 0.90 for a two-week interval). Scores on the scale could reflect different levels of resilience in populations that are thought to be differentiated (probable PTSD vs healthy controls, t(339) = -7.60, P < 0.01, Cohen's d = 0.84). Moreover, the total resilience scores were significantly negatively correlated with scores on total PTSD scale and its three subscales for all participants. Conclusion: The Chinese version of the 10-item CD-RISC has excellent psychometric properties, and is applicable for Chinese people.
The quick and the dry: Fast-absorbing and quick-drying wool fabrics with good washing durability are fabricated by functionalizing reactive siloxane monolayer on wool fiber surface, followed by grafting an ultrathin s...
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The electronic structure of （001） polar surface of cubic zirconia was studied by GGA（WC） approximation. We found the cubic lattice near （001） surface showed an intensive tendency to transfer to tetragonal lattic...
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The electronic structure of （001） polar surface of cubic zirconia was studied by GGA（WC） approximation. We found the cubic lattice near （001） surface showed an intensive tendency to transfer to tetragonal lattice. The metallic state appeared on both the terminations. For O-termination, some O2p states were vacated and hole carriers concentrated on surface oxygen-ions. For Zr-termination, some Zr4d states became partial occupied for the loss of O2p states. We observed the hole states were mainly localized at the corresponding ions on surface for both the terminations, while the charge states on Zr-termination were dispersed on surface.
A new strategy for development of electrochemical DNA biosensor based on site-specific DNA cleavage of restriction endonuclease and using quantum dots as reporter was reported in this paper The biosensor was fabricate...
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A new strategy for development of electrochemical DNA biosensor based on site-specific DNA cleavage of restriction endonuclease and using quantum dots as reporter was reported in this paper The biosensor was fabricated by immobilizing a capture hairpin probe, thiolated single strand DNA labeled with biotin group, on a gold electrode BfuCl nuclease, which is able to specifically cleave only double strand DNA but not single strand DNA, was used to reduce background current and Improve the sensitivity We demonstrated that the capture hairpin probe can be cleaved by BfuCl nuclease in the absence of target DNA, but cannot be cleaved in the presence of target DNA. The difference before and after enzymatic cleavage was then monitored by electrochemical method after the quantum dots were dissolved from the hybrids Our results suggested that the usage of BfuCl nuclease obviously Improved the sensitivity and selectivity of the biosensor. We successfully applied this method to the sequence-selective discrimination between perfectly matched and mismatched target DNA including a single-base mismatched target DNA, and detected as low as 3 3 x 10(-14) M of complementary target DNA Furthermore, our above strategy was also verified with fluorescent method by designing a fluorescent molecular beacon (MB), which combined the capture hairpin probe and a pair of fluorophore (TAMRA) and quencher (DABCYL) The fluorescent results are consistent with that of electroanalysis, further indicating that the proposed new strategy indeed works as we expected (C) 2010 Elsevier B.V. All rights reserved
Recently, wireless Sensor Networks (WSNs) have been paid more and more attention and are widely used in a lots of military and commercial applications. Due to the limited communication and computation capabilities, th...
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The microstructures and deformation behavior of Ti-based metallic powders were comprehensively investigated. It has been found that, with increasing the powder size, the phase constituent alters from pure glassy to gl...
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The microstructures and deformation behavior of Ti-based metallic powders were comprehensively investigated. It has been found that, with increasing the powder size, the phase constituent alters from pure glassy to glassy with crystalline phases (face centered cubic structured NiSnZr and hexagonal structured Ti3Sn phases). Our results suggest that the synergetic effect of the thermodynamics and kinetics determines the subsequent characteristics of the crystalline precipitations. Through comparative nanoindentation tests, it was found that the small powders exhibit more pop-in events and a larger pile-up ratio, suggesting that the plastic deformation of the metallic powders is governed by the combined effects of the free volume and the crystallization, which are determined by the cooling rate. (C) 2010 Elsevier B.V. All rights reserved.
＜正＞Carcinogenicity is an important toxicological endpoint that poses the highest concern for human *** this study,we develop a method that extracts structural alerts（SAs） and modulating factors of carcinogens bas...
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＜正＞Carcinogenicity is an important toxicological endpoint that poses the highest concern for human *** this study,we develop a method that extracts structural alerts（SAs） and modulating factors of carcinogens based on pure statistical ***,Gaston algorithm,as a frequent subgraph mining method,detects efficiently substructures of any size,shape,and level of chemical ***,building and pruning of a molecular fragments tree select SAs with statistical significance in binomial ***,modulating factors that are able to destroy the carcinogenicity potential of SAs are extracted by three self-defining *** results highlight that this method is a preferable method with higher accuracy,and the selected SAs are usable for prediction as well as ***,our method can extract SAs from database using an automated and unbiased manner which has no use of a priori knowledge of mechanism of action, and are conveniently employed by a user.
Here we present several computational models that reveal the prediction abilities in absorption by the human *** used a human intestinal absorption database contains 552 compounds to construct quantitative models and ...
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Here we present several computational models that reveal the prediction abilities in absorption by the human *** used a human intestinal absorption database contains 552 compounds to construct quantitative models and classification models for absorption *** descriptors calculation and model construction were performed in Discovery Studio and Pipeline Pilot software *** Function Approximation(GFA) and Recursive Partitioning(RP) served as two computational methods in our *** best GFA model for hiA achieves an R of 0.70 and an RMSE(root mean square error) of 15.96%for the training *** predictive power of the model was further evaluated by using a test set of 98 *** GFA model predicted the hiA with R =0.70 and RMSE=12.63%for the test set.A qualitative hiA model was presented in RP tree *** a further receiver operating characteristic(ROC) analysis,it gave a significant area under curve(AUC) value over 0.98,indicating a satisfactory predicting power.
Clinical observations suggest that depressed patients were less sensitive to experimental pain than healthy subjects. However, few animal studies are reported concerning the association of depression and pain. The pur...
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Clinical observations suggest that depressed patients were less sensitive to experimental pain than healthy subjects. However, few animal studies are reported concerning the association of depression and pain. The purpose of this study was to investigate the effects of unpredictable chronic mild stress (UCMS) induced depression on the perceived intensity of painful stimulation in rats. We measured the thermal and mechanical paw withdrawal thresholds (PWT) of normal and spinal nerve ligated (SNL) rats using hot plate test and von Frey test, respectively. The results showed that rats exposed to UCMS exhibited significantly higher thermal and mechanical pain thresholds in comparison to the non-depressed controls. In particular, the PWT of the SNL group was restored to nearly normal level after three weeks of UCMS, and even comparable to that of the control group. These results strongly suggest that the depressed subjects have decreased sensitivity to externally applied noxious stimulation, which is consistent with our previous findings. (C) 2010 Elsevier B.V. All rights reserved.
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