The emergence of multi-core computers has led to explosive development of parallel applications and hence the need of efficient schedulers for parallel jobs. Adaptive online schedulers have recently been proposed to e...
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ISBN:
(纸本)9780769539393
The emergence of multi-core computers has led to explosive development of parallel applications and hence the need of efficient schedulers for parallel jobs. Adaptive online schedulers have recently been proposed to exploit the multiple processor resource and shown good promise in theory. To verify the effectiveness of these parallel schedulers, it will be reassuring to test them extensively with various parallel workloads. Unfortunately it is still unknown how the job mixes will eventually evolve for multi-core computers;moreover, it is also non-obvious how the parallelism of a typical job will look like. To evaluate the dynamic behaviors of an adaptive scheduler under various scenarios, an ideal workload model for schedulers should thus allow the user to vary parallelism profiles of individual jobs as well as the job arrival patterns. In this paper, we present a tool called Malleable-Lab, which models malleable parallel jobs by extending the traditional moldable job models. Instead of generating a completely random parallelism, which does not allow clear account of the request-allocate responses, we identify several generic patterns of parallelism variations in parallel programs. Using Malleable-Lab we have evaluated two feedback-driven adaptive schedulers, namely, AG-DEQ (Adaptive-Greedy-DEQ) and ABG-DEQ (Adaptive B-Greedy-DEQ), and the well-known scheduler EQUI (Equi-partition). The results reveal that both feedback-driven schedulers outperform EQUI, but on the other hand suffer from high sensitivity to the scheduling overhead. We also found that ABG-DEQ exhibits better transient responses and stability than AG-DEQ. In conclusion, the tool has enabled us to analyze various aspects of the performance of online schedulers, and we have gained valuable insights for adaptive scheduling of parallel jobs on multiple processors.
Geographic information system (GIS) is increasingly managing very large sets of data, hence a centralized data index may not always provide the most scalable solution. Recently, the peer to peer (P2P) networks hav...
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Geographic information system (GIS) is increasingly managing very large sets of data, hence a centralized data index may not always provide the most scalable solution. Recently, the peer to peer (P2P) networks have become very popular for sharing information in a totally decentralized manner. In this paper, a new hybrid P2P spatial indexing network (HPSIN) is proposed, which combines distributed quad-tree with distributed Hash table (DHT) based Chord network to maintain both query efficiency and system load balance. In addition, a simple theoretical model based on opened queueing network for HPSIN is established. Assuming each peer as M/M/1 queueing processor in the model, fundamental characteristics of the system is captured, and expression of average query delay is obtained in close form. The theoretical analysis and numerical computing results show that there exists an optimum point of tradeoff between efficiency and load balance. By setting a proper value of start index level ls for different network scale and query rate, HPSIN will achieve the minimum overall query delay, therefore, can adapt to different P2P application environments.
In special networks, such as military or finance networks, terminal nodes deserve more attentions because of higher demands on reliability and survivability than switching nodes. A three nodes non-break-self-protectio...
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In special networks, such as military or finance networks, terminal nodes deserve more attentions because of higher demands on reliability and survivability than switching nodes. A three nodes non-break-self-protection unidirectional splitter-based ring is introduced and designed to protect the terminal nodes. The performances are compared with the traditional (existing) 1+2 protection scheme in terms of the cost, connection availability, recovery time and optical power budget. Calculation results show this proposed scheme can keep data integrity and has very high survivability and connection availability, while the cost, recovery time and power budget are acceptable. Copyright (C) 2010 John Wiley & Sons, Ltd.
Shaker-like potassium channels in plants play an important role in potassium absorption and transport. Here, we characterized 11 genes encoding shaker-like channels from Populus trichocarpa. Furthermore, two homologs ...
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Shaker-like potassium channels in plants play an important role in potassium absorption and transport. Here, we characterized 11 genes encoding shaker-like channels from Populus trichocarpa. Furthermore, two homologs from this family were isolated from Populus euphratica and named PeKC1 and PeKC2. Subcellular localization analysis of them in Nicotiana benthamiana revealed that they are located in the cell membrane. Yeast two-hybrid assays showed that they not only interacted strongly with PeCIPK24, a homolog of AtCIPK23, but also interacted with several other CIPK members, including PeCIPK10 and PeCIPK17. To further analyze their function, we over-expressed PeKC1 or PeKC2 in akt1 mutant, the results show that the transgenic plant can recover the mutant phonotype sensitive to low-K+ stress. This means PeKC1 or PeKC2 can complement the function of AKT1 in akt1 mutant, involved in the CBL1-CIPK23 signal transduction pathway and play an important role under low-K+ stress.
Based on the potential decolorization ability of Pseudomonas sp strain DY1 a Plackett-Burman design was used to select the operational parameters for decolorization of heavy metal-containing dye Acid Black 172 Four si...
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Based on the potential decolorization ability of Pseudomonas sp strain DY1 a Plackett-Burman design was used to select the operational parameters for decolorization of heavy metal-containing dye Acid Black 172 Four significant parameters including pH temperature concentrations of Fe3+ and NaH2PO4 were optimized A quadratic model obtained from the response surface design was constructed on experimental data The optimal condition for decolorization was found to be pH 623 30 degrees C 8 0 mM of Fe3+ and 10 0 g/L of NaH2PO4 The confirmatory experiments (86 0% decolorization percentage within the confidence Interval) subsequently verified the accuracy of the experimental model Moreover the decolorization under the optimal condition fitted the logarithmic model well (R-2 = 0 964) This strain really offers an alternative for bioremediation of soil or water contaminated by heavy metal-containing dye (C) 2010 Elsevier Ltd All rights reserved
Coal bio-oil slurries (CBS) with different coal concentrations are prepared by mixing Yangquan anthracite and biomass fast pyrolysis oil. The rheological properties of CBS are examined. The result shows that the solid...
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Coal bio-oil slurries (CBS) with different coal concentrations are prepared by mixing Yangquan anthracite and biomass fast pyrolysis oil. The rheological properties of CBS are examined. The result shows that the solid concentration of CBS can reach 42% without any additives. The rheological behavior of the prepared CBS can be described by the Bingham plastic fluid model. Its apparent viscosity decreases with increasing shear rates, and the yield stress increases with increasing solid concentrations. The CBS keeps its static stability for 3-4 days with no formation of soft sediment. The steam gasification experiment of CBS is carried out on a lab-scale apparatus with a fixed bed reactor. The effects of reaction temperature and steam to carbon ratio (S/C) on the gas yield and component distribution are investigated. The result shows that the yield of H-2 and CO increases with temperature and that the ratio of H-2/CO decreases with temperature and increases with S/C. The higher heating value of the gas product is about 12 MJ/Nm(3).
A wearable exoskeleton upper limb rehabilitation robot developed in our lab consists of 8 active joints and one passive joint. Each active joint is powered by two pneumatic muscles (PMs) in opposing pair configuration...
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ISBN:
(纸本)9783642165863
A wearable exoskeleton upper limb rehabilitation robot developed in our lab consists of 8 active joints and one passive joint. Each active joint is powered by two pneumatic muscles (PMs) in opposing pair configuration through a steel wire with a flexible sleeve. A tension device is used to keep the steel wire in pulley slot. These factors incorporate with characteristics of PM make the rehabilitation robot system so complex (nonlinear, time-varying and time-delay) that it is difficult to model the robotic arm precisely. The characteristics of the shoulder-joint are experimentally studied in this article, which is helpful to design the controllers of the robot.
Prior studies suggested that angiotensin-converting enzyme (ACE) affected vascular homeostasis and degradation of amyloid beta (A beta). It is associated with the therapeutic outcome in major depression. The aim of th...
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Prior studies suggested that angiotensin-converting enzyme (ACE) affected vascular homeostasis and degradation of amyloid beta (A beta). It is associated with the therapeutic outcome in major depression. The aim of this study was to investigate the association between angiotensin-converting enzyme (ACE) insertion/deletion (VD) polymorphism and structural abnormalities in remitted geriatric depression (RGD), and test the relationship of neuropsychological performances and regional white matter volumes. 31 RGD patients were recruited and neuropsychological tests, magnetic resonance imaging (MRI) and genotype of ACE I/D were examined for each subject. The differences in regional white matter volume were tested between I homozygotes and D-allele carriers (I/D or D/D genotype) by optimized VBM. D-allele carriers exhibited significantly smaller white matter volumes of right superior frontal gyrus (SFG) and right anterior cingulated gyrus (ACG), but had larger volumes of left middle temporal gyrus (MTG) and right middle occipital gyrus (MOG) than I homozygotes (P<0.001). Meanwhile, there was a significant positive correlation between white matter volume enlargement of left MTG and Symbol Digit Modalities Test (SDMT) (r=0.456, P=0.043), and the reduction of right ACG was negatively related to Clock Drawing Test (CDT) performance (r=0.445, P=0.050) in D-allele carriers. The finding suggests that ACE can modulates the pathology of RGD, the left MTG and right ACG might be involved in the pathophysiology of cognitive dysfunction in RGD patients. (C) 2010 Elsevier Ireland Ltd. All rights reserved.
The IEEE 802.15.4 is one of the low-layer communication standards for personal area networks (PANs) and wireless sensor networks (WSNs), which may be interfered by other wireless devices in the industrial, scienti...
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The IEEE 802.15.4 is one of the low-layer communication standards for personal area networks (PANs) and wireless sensor networks (WSNs), which may be interfered by other wireless devices in the industrial, scientific and medical (ISM) frequency bands, especially in home environment, such as devices of IEEE 802.1 lb, Bluetooth, cordless telephone, and microwave oven radiation. This article examines the mutual interference effects of 2.4 GHz devices widely deployed at home, via both theoretical analysis and real-life experiment. An analytical model is proposed to estimate the packet error rate (PER) of radio frequency (RF) coexistent networks. The model is verified through a series of experiments. The experimental results also show that Bluetooth has little impact of interference on IEEE 802.15.4 sensor networks, and that the effect of microwave oven radiation on IEEE 802.15.4 sensor devices is tolerable if the device is a few meters away from the oven. Whereas, IEEE 802.1 lb wireless networks can cause problems to IEEE 802.15.4, however the effects can be significantly reduced by a proper channel selection. This article also proposes the interference duration model, which will be helpful in modeling of coexistence simulation. Simulation results show that the stationary scenario obeys the experiments result very well.
Tetraspanin CD151 is involved in several pathological activities associated with tumor progression, including neoangiogenesis. However, the role and molecular mechanism of CD151 in the neoangiogenesis of hepatocellula...
Tetraspanin CD151 is involved in several pathological activities associated with tumor progression, including neoangiogenesis. However, the role and molecular mechanism of CD151 in the neoangiogenesis of hepatocellular carcinoma (HCC) remain enigmatic. We found that the level of expression of matrix metalloproteinase 9 (MMP9) was positively associated with CD151 expression in HCC cells. We developed a zone-by-zone blockade and demonstrated that overexpression of CD151 in HCC cells facilitated MMP9 expression through a phosphatidylinositol-3-kinase (PI3K)/protein kinase B (Akt)/glycogen synthase kinase 3 beta (GSK-3 beta)/Snail signaling pathway. In contrast, down-regulation of CD151 expression impaired the ability of HCC cells to form microvessels in vitro and reduced their in vivo metastatic potential. In a clinical setting, a significant correlation of the expression of CD151 with MMP9 expression and with microvessel density (MVD) was revealed by Pearson correlation analysis of HCC patients. The postoperative 3-, 5-, and 7-year overall survival rates of HCC patients with CD151(high)/MMP9(high)/MVDhigh were significantly lower than those of the CD151(low)/MMP9(low)/MVDlow group or groups in which only one or two of CD151, MMP9, and MVD were highly expressed. Cumulative recurrence rates were also highest in HCC patients with CD151(high)/MMP9(high)/MVDhigh in comparison with the other groups. Multivariate Cox proportional hazards analysis showed that the concomitant overexpression of CD151, MMP9, and MVD was an independent marker for predicting poor prognosis of HCC. Conclusion: Overexpression of CD151 up-regulated the expression of MMP9 through the PI3K/Akt/GSK-3 beta/Snail pathway. CD151-dependent neoangiogenesis appeared to promote the progression of HCC, and this suggests that CD151 may be useful as a high-priority therapeutic target for antiangiogenesis in HCC. (HEPATOLOGY 2010;52:183-196)
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