Previous research efforts in deepfake detection mainly concentrated on identifying anddifferentiating artifacts discernible to humans. Those methods have left a bias in learned models, as they tend to concentrate on ...
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Previous research efforts in deepfake detection mainly concentrated on identifying anddifferentiating artifacts discernible to humans. Those methods have left a bias in learned models, as they tend to concentrate on the disparities between forged and natural regions from the perspective of a single sample while overlooking consistency within categories from the perspective of the entire sample set, which remains crucial across various real-world applications. Therefore, inspired by contrastive learning, we tackle the deepfake detection problem by learning the invariant representations of both categories. Our proposed method, termed Centroidbased Contrastive Consistency Learning (C3L) method, integrates constraints on representations at both the data preprocessing and feature extraction stages. Specifically, during data preprocessing, we consider both temporal relationships within videos and the latent relationships within synthesis data. We introduce a novel Positive Enhancement Module (PEM) designed to characterize natural and forged samples in a facial semantically irrelevant way, thereby guiding a task-oriented positive pair contrasting strategy. In addition, at the feature extraction stage, we introduce the Margin Feature Simulation Module (MFSM), which leverages the centroid of the natural category to simulate marginal features for both categories. Subsequently, we employ the Supervised Contrastive Margin Loss (SCML), utilizing simulated features to emphasize differences at decision boundaries and optimize the learning process. The effectiveness androbustness of the proposed method have been demonstrated through extensive experiments.
In the H-mode experiments conducted on the Experimental Advanced Superconducting Tokamak(EAST),fluctuations induced by the so-called edge localized modes(ELMs)are captured by a high-speed vacuum ultraviolet(VUV)imagin...
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In the H-mode experiments conducted on the Experimental Advanced Superconducting Tokamak(EAST),fluctuations induced by the so-called edge localized modes(ELMs)are captured by a high-speed vacuum ultraviolet(VUV)imaging *** field line-aligned filamentary structures are analyzed in this *** transport induced by ELM filaments in the scrape-off layer(SOL)underdifferent discharge conditions is analyzed by comparing the VUV signals with the divertor probe *** is found that convective transport along open field lines towards the divertor target dominates the parallel ion particle transport mechanism during *** toroidal mode number of the filamentary structure derived from the VUV images increases with the electron density pedestal *** analysis of the toroidal distribution characteristics during ELM bursts reveals toroidal *** influence of resonance magnetic perturbation(rMP)on the ELM size is also analyzed using VUV imaging *** the phase difference of the coil changes periodically,the widths of the filaments change as ***,the temporal evolution of the ELMs on the VUV signals provides rise time anddecay time for each single ELM event,and the results indicate a negative correlation trend between these two times.
When a crowdsourcing approach is used to assist the classification of a set of items,the main objective is to classify this set of items by aggregating the worker-provided labels.A secondary objective is to assess the...
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When a crowdsourcing approach is used to assist the classification of a set of items,the main objective is to classify this set of items by aggregating the worker-provided labels.A secondary objective is to assess the workers’skill levels in this process.A classical model that achieves both objectives is the famous dawid-Skene *** this paper,we consider a third objective in this context,namely,to learn a classifier that is capable of labelling future items without further assistance of crowd *** extending the dawidSkene model to include the item features into consideration,we develop a Classification-Orienteddawid Skene(COdS)model,which achieves the three objectives *** effectiveness of COdS on this three dimensions of the problem space is demonstrated experimentally.
In the process of extracting ion-absorbedrare earth ore(IrEO),the production of radioactive waste is a major environmental *** address this issue,MoS_(2) was used to modify ion-absorbedrare earth tailings(rET) to sy...
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In the process of extracting ion-absorbedrare earth ore(IrEO),the production of radioactive waste is a major environmental *** address this issue,MoS_(2) was used to modify ion-absorbedrare earth tailings(rET) to synthesize a novel MoS_(2)@rET composite material for the effective handling of radioactive waste generated in IrEO separation *** composite material was thoroughly characterized using various analytical techniques,including X-ray diffraction(Xrd),X-ray photoelectron spectroscopy(XPS),thermogravimetry(TG),Fourier-transform infrared(FTIr),scanning electron microscopy(SEM),Brunaue r-Emmett-Teller(BET) and energy dispersive spectroscopy(EdS).By optimizing the operating parameters,the optimal experimental conditions were determined to be pH=3,contact time=60 min,liquid-solidratio=6 g/L,and initial concentration=150 mg/*** adsorption data fitted well with the pseudo second-orderrate *** thermodynamic parameters concerning the adsorption of Th(Ⅳ) were analyzed and *** isotherm model is a more fitting choice for the adsorption process compared to the Freundlich isotherm ***_(2)@rET was used in the acid leachate of IrEO waste residue,achieving the separation of Th andrare earth *** mechanism of Th(Ⅳ) adsorption by MoS_(2)@rET was investigated,revealing that the adsorption process involves electrostatic interactions,chemical bonding,andredox *** above research results indicate that MoS_(2)@rET composite materials have application potential in the sustainable treatment of IrEO radioactive waste.
Locoregionally advanced laryngeal and hypopharyngeal cancers(LA-LHCs)are traditionally treated with surgery followed by postoperative radiotherapy,which impairs speech and swallowing functions andreduces the quality ...
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Locoregionally advanced laryngeal and hypopharyngeal cancers(LA-LHCs)are traditionally treated with surgery followed by postoperative radiotherapy,which impairs speech and swallowing functions andreduces the quality of life.^(1,2)The use of induction chemotherapy(IC)as a larynxpreserving approach for LA-LHCs has been verified andrefined.^(3)However,the short-term tumorresponse to IC varies,non-responders usually show poor survival and little benefit.
In the laser powder bed fusion (LPBF) process, the surface quality of intermediate layers impacts interlayer bonding andpart forming quality. due to the complex dynamic process inherent in LPBF, current monitoring me...
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In the laser powder bed fusion (LPBF) process, the surface quality of intermediate layers impacts interlayer bonding andpart forming quality. due to the complex dynamic process inherent in LPBF, current monitoring methods struggle to achieve high-quality in situ online monitoring, which limits the in-depth understanding of the evolution mechanisms of the surface morphology of LPBF intermediate layers. This paper employs an optimized coaxial optical imaging method to monitorkey LPBF processes and analyzes the intermediate layer surface morphology evolution mechanism considering heat, force, and mass transfer. results indicate that LPBF intermediate layer surfaces are influenced by energy density, melt pool behavior, and previous layer morphology, forming complex topological structures. At a low energy density, insufficient powder melting causes balling, extended by subsequent melt pools to form a reticulated structure and local large-scale protrusions. Heat accumulation at a high energy density promotes melt pool expansion, reduces melt track overlap, and effectively eliminates defects from previous layers via remelting, with spatter becoming the main defect. Additionally, the melt pool wettability on the part contours captures external powder, forming unique, overhanging contour protrusions. This paper enhances understanding of LPBF intermediate layer surface morphology formation mechanisms and provides a theoretical basis for optimizing surface quality.
It has been found that thymol(Thy)androsmarinic acid(ros-A)improve the growth performance of piglets andrelieve intestinal inflammation in *** effects of Thy andros-A separately or in combination(Thyros-A)on the i...
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It has been found that thymol(Thy)androsmarinic acid(ros-A)improve the growth performance of piglets andrelieve intestinal inflammation in *** effects of Thy andros-A separately or in combination(Thyros-A)on the intestinal function and health of piglets challenged with Escherichia coli K88(*** K88)were investigated.A total of 30 piglets aged 21 d were assigned to 5 groups(n=6).The control(Con)and K88 groups piglets received a basal diet,while the Thy,ros-A,and Thyros-A groups were fed a basal diet supplemented with 500 mg/kg Thy,500 mg/kg ros-A,and 250 mg/kg Thy t 250 mg/kg ros-A,*** the 19th and 20th day,piglets in the K88,Thy,ros-A,and Thyros-A groups were orally administered 10 mL of phosphate-buffered saline(PBS)containing approximately 1109 CFU/mL of *** K88,while the Con group received an equal volume of *** results showed that the Thyros-A treatment reduced the damage to ileal villi induced by the *** K88 challenge,leading to longer villi in the ileum(P<0.05).Thy andros-A modulated the composition of the ileal *** to the K88 group,the Thyros-A group had a higher abundance of Lactobacillus andromboutsia,while Escherichia-Shigella anddesulforvibrio were lower(P<0.05).Additionally,the Thyros-A group showed elevated levels of gene and protein expressions for zonula occludens-1,occludin,and claudin-1 compared to the K88 group(P<0.05).In conclusion,combining Thy andros-A reduced ileal damage andrelieved the inflammation in weaned piglets challenged with *** K88 by regulating intestinal microflora and improving barrier function.
Backgrounddrug-drug interactions (ddIs) especially antagonistic ones present significant risks to patient safety, underscoring the urgent need forreliable prediction methods. recently, substructure-basedddI predicti...
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Backgrounddrug-drug interactions (ddIs) especially antagonistic ones present significant risks to patient safety, underscoring the urgent need forreliable prediction methods. recently, substructure-basedddI prediction has garnered much attention due to the dominant influence of functional groups and substructures on drug properties. However, existing approaches face challenges regarding the insufficient interpretability of identified substructures and the isolation of chemical *** study introduces a novel framework forddI prediction termed HdN-ddI. HdN-ddI integrates an explainable substructure extraction module to decompose drug molecules andrepresents them using innovative hierarchical molecular graphs, which effectively incorporates information from real chemical substructures and improves molecules encoding efficiency. Furthermore, the enhanceddual-view learning method inspired by the underlying mechanisms of ddIs enables HdN-ddI to comprehensively capture both hierarchical structure and interaction information. Experimental results demonstrate that HdN-ddI has achieved state-of-the-art performance with accuracies of 97.90% and 99.38% on the two widely-useddatasets in the warm-start setting. Moreover, HdN-ddI exhibits substantial improvements in the cold-start setting with boosts of 4.96% in accuracy and 7.08% in F1 score on previously unseen drugs. real-world applications further highlight HdN-ddI's robust generalization capabilities towards newly approved *** its accurate predictions androbust generalization across different settings, HdN-ddI shows promise for enhancing drug safety and efficacy. Future research will focus on refining decomposition rules as well as integrating external knowledge while preserving the model's generalization capabilities.
We investigated the efficiency of charge-to-spin conversion in two-dimensional rashba altermagnets,a class of materials that combines the characteristics of both ferromagnets and *** quantum linearresponse theory,we ...
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We investigated the efficiency of charge-to-spin conversion in two-dimensional rashba altermagnets,a class of materials that combines the characteristics of both ferromagnets and *** quantum linearresponse theory,we quantified the longitudinal and spin Hall conductivities in this system anddemonstrated a substantial enhancement in the spin Hall angle below the band crossing point through the dual effects of relativistic spin–orbit interaction and nonrelativistic altermagnetic exchange ***,the results showed that the skew scattering and intrinsic mechanisms arising from Fermi sea states are almost negligible in this system,in contrast to conventional ferromagnetic rashba *** findings not only elucidate the spin dynamics in rashba altermagnets but also pave the way fordeveloping novel strategies for manipulating charge-to-spin conversion via sophisticated control of noncollinear and collinear out-of-plane spin textures.
The reduction in methane concentration is crucial for achieving the goals of the Paris agreement. However, its annual growth rate is unstable, and understanding the reasons for changes in methane growth is essential f...
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The reduction in methane concentration is crucial for achieving the goals of the Paris agreement. However, its annual growth rate is unstable, and understanding the reasons for changes in methane growth is essential for climate policy-making. Currently, there is considerable uncertainty regarding its attribution. Here, we utilize multi-source data and optimal fingerprinting methods to detect the contributions of several keydrivers to the methane trend and interannual variability. We find that the methane growth trend is primarily influenced by anthropogenic emissions, while interannual variability is predominantly determined by wetland and biomass burning emissions. This result underscores the central role of anthropogenic emissions in methane dynamics, providing confidence in the effectiveness of human efforts to control methane atmospheric concentrations through emission reductions. It also helps alleviate concerns about the recent surge in atmospheric methane concentration, as it may be a short-term peak caused by increased wetland emissions rather than a long-term change.
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