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Preparation and characterization of foamed ceramics from silicomanganese and fluorgypsum waste

INTERNATIONAL JOURNAL OF APPLIED CERAMIC TECHNOLOGY 2025年第1期22卷

作者： Dong, Xiongwei Han, Fenglan Li, Ning Dong, Fuyuan Liu, Haipeng Neng, Yu Li, Maohui North Minzu Univ Sch Mat Sci & Engn Yinchuan 750021 Peoples R China Huadian Elect Power Res Inst Co Ltd Hangzhou Peoples R China

High-strength foamed ceramics were synthesized employing silicon-manganese slag (SM) and fluorgypsum (FG) as raw materials, with SiC serving as the foaming agent. Investigations into the influence of firing temperature and FG content on the phase structure, microstructure, and physical properties of foam ceramics were conducted. Characterization of the samples was performed through X-ray diffraction and scanning electron microscopy. Results indicate that an increase in FG content lowers the matrix melting point, promotes crystal growth, enhances compressive strength, and forms a uniform pore structure. At an FG content of 11%, ceramics prepared at a firing temperature of 1130 degrees C exhibit a density of 0.56 g/cm3, porosity of 78.45%, and compressive strength of 3.05 MPa. This study explores the use of FG as a cost-effective alternative to borax, demonstrating a sustainable approach for foam ceramics preparation using silicomanganese slag and FG synergy.

关键词： compressive strength firing temperature fluorgypsum silicon-manganese slag

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NRF-1 promotes FUNDC1-mediated mitophagy as a protective mechanism against hypoxia-induced injury in cardiomyocytes

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EXPERIMENTAL CELL research 2025年第1期446卷 114472页

作者： Li, Junliang Li, hui Niu, Nan Zhu, Yazhou Hou, Siyu Zhao, Wei Ningxia Med Univ Sch Basic Med 1160 Shengli St Yinchuan 750004 Ningxia Peoples R China Ningxia Key Lab Prevent & Control Common Infect Di Yinchuan Peoples R China

Hypoxia-induced apoptosis and mitochondrial dysfunction in cardiomyocytes are involved in the mechanisms of heart failure. Our previous studies have confirmed that NRF-1 alleviates hypoxia-induced injury by promoting mitochondrial function and inhibiting apoptosis in cardiomyocytes. However, the mechanism by which NRF-1 attenuates hypoxia-induced injury in cardiomyocytes is still unclear. Mitophagy, a selective autophagy, has recently shown a remarkable correlation with hypoxia-induced cardiomyocyte injury. In this study, we evaluated whether NRF-1 protects cardiomyocytes from hypoxia-induced injury by regulating mitophagy. The findings indicate that hypoxia prevents H9c2 cells from growing, encourages mitochondrial dysfunction, and triggers mitophagy. In addition, promoting mitophagy by rapamycin reduces hypoxia-induced injury in H9c2 cells. Overexpression of NRF-1 in hypoxia-induced H9c2 cells promotes mitophagy and alleviates cell injury, and this effect can be inhibited by 3-MA. Further study found that NRF-1 promotes the expression of FUNDC1 by binding to its promoter region. Knockdown of FUNDC1 in NRF-1 over-expression H9c2 cells inhibited mitophagy and aggravated hypoxia-induced injury. In conclusion, our study suggests that NRF-1 protects against hypoxiainduced injury by regulating FUNDC1-mediated mitophagy in cardiomyocytes.

关键词： Heart failure Hypoxia H9c2 cardiomyocytes NRF-1 Mitophagy FUNDC1

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The application of the drug flushing covered stent grafts in endovascular repair of aortic aneurysms caused by brucellosis

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BMC INFECTIOUS DISEASES 2025年第1期25卷 1-13页

作者： Ma, Lilong Yang, Haibo Wang, Yaojie Zhang, Hua Li, Chao Jiang, Fudong Li, Youjin Ningxia Med Univ Peoples Hosp Ningxia Hui Autonomous Reg Dept Cardiac & Vasc Surg Yinchuan Peoples R China

ObjectiveBrucellosis-induced aortic aneurysm (BIA), as a rare yet highly life-threatening type of infectious aortic aneurysm, currently lacks standardized treatment protocols. The primary objective of this study is to thoroughly evaluate the safety and efficacy of endovascular therapy using a combination of covered stents and drug irrigation techniques for the treatment of BIA. This endeavor aims to provide a scientific basis for the clinical management of this *** study employed a retrospective analysis approach to systematically collect comprehensive clinical data from patients with infectious aortic aneurysms admitted to three independent campuses of the same hospital from January 2016 to January 2024. The analysis encompassed a wide range of aspects, including patients' epidemiological characteristics, diverse clinical manifestations, detailed laboratory test reports, computed tomography angiography imaging data of the thoracoabdominal aorta(CTATA), specific treatment strategies, and prognosis during follow-up. The aim of this study is to provide robust support for optimizing the treatment strategies of Brucella-induced aortic aneurysms through comprehensive and in-depth data *** the 27 confirmed cases of infectious aortic aneurysm, a striking 51.7% (n = 15) were unequivocally diagnosed as a consequence of brucellosis-induced aneurysmal formation. Direct confirmation of brucellosis via blood culture succeeded in merely 6 cases (40%), with the remainder being verified through the combination of the Rose Bengal plate agglutination and tube agglutination tests specific to Brucella. Gender distribution among these 15 patients was heavily skewed, with a significant majority being male (n = 13) contrasting with just 2 females. Their ages spanned a range from 47 to 75 years. Delving deeper, 11 patients had a documented history of contact with cattle, sheep, pigs, or their derivatives, whereas 4 did not present with such definitive exposu

关键词： Brucellosis Aortic aneurysm Drug flushing technique of covered stent Endovascular repair

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Irradiation of 125I seeds blocks glycolysis in pancreatic cancer by inhibiting KLF5 m6A methylation through the suppression of RBM15

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EXPERIMENTAL CELL research 2025年第1期448卷 114538页

作者： Song, Jianjun Kang, Fuping Chang, Xiaoning Wu, Jing Zhang, Peng Wang, Xiaolong Wang, Feng Ningxia Med Univ Gen Hosp Dept Hepatobiliary Surg Yinchuan Peoples R China Ningxia Med Univ Gen Hosp Dept Rehabil Med Yinchuan Peoples R China Ningxia Med Univ Gen Hosp Med Expt Ctr Yinchuan Peoples R China Zhengzhou Inst Ind Applicat Technol Sch Nursing Xinzheng Peoples R China

This paper investigated whether 125I seed irradiation for pancreatic cancer treatment was mediated through the RBM15/KLF5 pathway in glycolysis. The study collected peripheral blood from pancreatic cancer patients, and detected the expression of RBM15 and KLF5 expression in the serum of pancreatic cancer patients before and after 125I seed irradiation. An in vitro study was conducted to investigate the effects 125I seed irradiation on the malignant behavior and glycolysis of pancreatic cancer cells. The underlying mechanisms were thoroughly examined through a series of logical experiments, including Western blot analysis, Dot-blot experiment, methylated RNA immunoprecipitation assay, and RNA pull down assay. A xenograft tumor model in nude mice was established and treated with 125I seed irradiation, which was employed to research the in vivo effect and mechanism of 125I seed irradiation for pancreatic cancer. The overexpressed RBM15 and KLF5 in serum of pancreatic cancer patients were reduced after 125I seed treatment. 125I seed treatment impaired pancreatic cancer cell proliferation and invasion;enhanced apoptosis;attenuated glycolysis;and reduced RBM15 and KLF5 expression. RBM15 overexpression partially reversed these influences of 125I seed treatment on pancreatic cancer cells. RBM15 was capable of increasing KLF5 expression, which might be achieved by promoting m6A methylation of KLF5. In vivo, 125I seed treatment blocked the growth of pancreatic cancer cells and decreased RBM15 and KLF5 expression in xenograft tumor, whereas RBM15 overexpression abolished these effects. 125I seed irradiation suppressed glycolysis in pancreatic cancer by inhibiting KLF5 m6A methylation through down-regulation of RBM15. This discovery established a solid foundation for the use of in the treatment of pancreatic cancer.

关键词： Pancreatic cancer 125I seed irradiation Glycolysis RBM15 KLF5 m6A methylation

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Prospecting artificial microbial consortia toward lignin valorization

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CHEMICAL ENGINEERING JOURNAL 2025年 512卷

作者： Hu, Jian-Ning Gao, Bo-Chao Liu, Zhi-Hua Li, Xia Yuan, Ying-Jin Li, Bing-Zhi Tianjin Univ Sch Chem Engn & Technol Tianjin 300072 Peoples R China Frontiers Sci Ctr Synthet Biol State Key Lab Synthet Biol Tianjin 300072 Peoples R China Tianjin Univ Frontiers Res Inst Synthet Biol Tianjin 301799 Peoples R China

Lignin, an important aromatic polymer abundant in the structural components of plant cell walls, represents a significant carbon resource for sustainable biorefineries. Microbial consortia exhibit enhanced adaptability and stability in response to environmental changes, as well as in spatial and temporal organization. Lignin valorization has long been a challenge in biorefineries, and microbial consortia are proposed as promising mediators in this process. This review divides lignin valorization into two main areas: lignin biodepolymerization and bioconversion, while also exploring the construction of microbial consortia. The review begins with a survey of the pathways and key enzymes involved in lignin biodepolymerization and bioconversion, followed by a detailed examination of the synergistic mechanisms within microbial communities. It then summarizes previous applications of microbial consortia for lignin depolymerization and conversion. Additionally, principles for constructing and enhancing microbial consortia are presented. Finally, the review discusses the impact of advancements in synthetic biology and artificial intelligence on the development of microbial consortia for lignin valorization. The rational design of microbial consortia could enhance the practicality of lignin valorization from biodepolymerization to bioconversion.

关键词： Artificial microbial consortia Lignin valorization Bioconversion Collaborative mechanisms Construction principles Synthetic biology

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Health Risk of Heavy Metal and Implication for Ecological Threat in Soils Weathered from the Black Shale

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BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY 2025年第2期114卷 1-9页

作者： Zhao, Wanfu Song, Yinxian Li, Wei Wen, Yubo Ji, Junfeng Nanjing Univ Sch Earth Sci & Engn Minist Educ Key Lab Surficial Geochem Nanjing 210023 Peoples R China Ningxia Inst Land Resources Survey & Monitor Yinchuan 750002 Peoples R China Kunming Univ Sci & Technol Fac Land Resource Engn Dept Geosci Kunming 650093 Peoples R China Nantong Univ Sch Geog Sci Nantong 226019 Peoples R China

Heavy metals were analyzed in rhizosphere soils and rice grains collected from typical black shale areas. The concentrations of As, Cd, Cu, and Zn in the rhizosphere soil exceeded the current soil environmental quality standards. Cd exhibited the highest bioaccumulation capacity, with 45% of rice grains exceeding food safety limit. Structural equation modeling (SEM) revealed that soil organic matter indicated that 34.79% of rice Cd accumulation and approximately 10%-25% of other metals were inhibited. Multiple regression modelling showed that in areas with high geological background of black shales, the screening and intervention values for soil Cd were adjusted to 0.24 mg kg-1 and 0.42 mg kg-1 for pH <= 5.5 and 0.27 mg kg-1 and 1.66 mg kg-1 for pH 5.5 - 6.5 respectively. Primary exposure pathways for non-carcinogenic risks were identified as food ingestion and skin contact. This study provides fundamental information for land use application and development in region with high geological background.

关键词： High geological background Black shales Heavy metals SEM Ecological risk

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Recent advances in cold plasma technology for enhancing the safety and quality of meat and meat products: A comprehensive review

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FOOD research INTERNATIONAL 2025年 202卷 115701页

作者： Zhang, Changyan Luo, Yulong Deng, Ziyao Du, Rui Han, Mei Wu, Junqin Zhao, Wenxiu Guo, Rong Hou, Yanru Wang, Songlei Ningxia Univ Sch Food Sci & Engn Yinchuan 750021 Peoples R China Yinchuan Agr & Rural Bur Yinchuan Agr Prod Qual Testing Ctr Yinchuan 750021 Peoples R China

Meat and meat products constitute an important component of the diet for several populations around the world and fulfill various nutritional requirements of the human body. However, owing to the inherent characteristics of meat including its susceptibility to oxidation and contamination with foodborne pathogens meat and meat products perish easily. In recent years, with improvements in living standards and increased focus on nutrition and health among consumers, non-thermal food processing technologies have received increasing attention. Among these strategies, cold plasma (CP) technology has emerged as a promising and novel processing technique with substantial potential in preserving meat and meat products. In this review, we discussed and analyzed the effects of CP on the nutritional value, sensory quality, and safety of meat and meat products, particularly, the potential toxicological hazards. Furthermore, we provided a detailed introduction to the mechanisms about how CP affects microorganisms, highlighting its role in inducing apoptosis and inhibiting quorum sensing. In the base of these theoretical foundations, this paper proposed several practical recommendations in order to optimize CP technology. Finally, we summarized the potential applications of CP in meat preservation, aiming to establish a theoretical framework for further research and application of this technology.

关键词： Cold plasma systems Meat nutrition and safety Antiseptic preservation Non-thermal processing

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Laser-Induced Porous Graphene-Based Materials and Its Potential Application in Lithium-Ion Batteries

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ACS OMEGA 2025年第11期10卷 11241-11249页

作者： Ma, Xiao Wang, Shaoqing Fu, Zilong Gao, Hongyi Shao, Yan Li, Xiaoguang Yan, Xiaoyun China Univ Min & Technol Beijing Sch Geosci & Surveying Engn Beijing 100083 Peoples R China Chinese Acad Sci Inst Geol & Geophys Inst Ctr Shared Technol & Facil Beijing 100029 Peoples R China Gen Prospecting Inst China Natl Adm Coal Geol Beijing 100039 Peoples R China

Laser-induced coal-based graphene (C-LIG) is a promising field in energy materials research that focuses on converting abundant coal resources into high-value graphene-based materials using low-cost and environmentally friendly processes. In this study, we successfully produced few-layer graphene from low-volatility bituminous coal under vacuum conditions using carbon dioxide infrared laser equipment. The results showed that the laser-induced graphene consists predominantly of 2-5 layers, featuring multipore structures with smaller-size pores on the pore walls. It also exhibits large interlayer spacing with the layers arranged in a long-range disorder, demonstrating high crystallinity and significant expansion of the aromatic layers. Notably, the interlayer spacing increases as the number of graphene layers decreases. When used as an anode material for lithium-ion batteries, C-LIG demonstrates a high specific capacity of 330 mA h g-1 at 0.1 A g-1, outperforming commercial graphite-based batteries. The expended interlayer spacing and unique pore structure promote rapid lithium-ion transfer, enhancing the storage performance. These findings suggest that C-LIG holds great potential for applications in electrochemical energy storage.

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Structure-function-guided synergistic fractionation enhances valorization of wheat straw biomass

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CHEMICAL ENGINEERING JOURNAL 2025年 508卷

作者： He, Zi-Jing Xu, Tao Liu, Shi-Chang Ragauskas, Arthur J. Li, Bing-Zhi Yuan, Ying-Jin Liu, Zhi-Hua Tianjin Univ Frontiers Sci Ctr Synthet Biol Sch Chem Engn & Technol Tianjin 300072 Peoples R China Tianjin Univ Sch Chem Engn & Technol Key Lab Syst Bioengn Minist Educ Tianjin 300072 Peoples R China Tianjin Univ Frontiers Res Inst Synthet Biol Tianjin Peoples R China Univ Tennessee Dept Chem & Biomol Engn Knoxville TN 37996 USA

Valorizing biomass into multifunctional composite nanocellulose films (MCNF) can revolutionize traditional biorefineries and sustainable material fabrication. The present study exploited structure-function-guided fractionation and valorization for wheat straw to develop MCNF toward flexible pressure sensing applications. The deigned synergistic fractionation enabled the selective composition separation by synergistically breaking the glycosidic bond of hemicellulose and cleaving the C-O bonds of lignin, resulting in a high-brightness cellulose fraction with suitable properties and a soluble lignin stream. The developed nanoization technologies achieved nanocellulose with a remarkable average particle size of less than 35 nm and a uniform structure. The interdependence analysis highlighted that the tensile strength and Young's modulus of nanocellulose films were positively correlated with cellulose crystallinity and inversely correlated with lignin content. Additionally, small nanocellulose particles and low lignin content boosted the toughness and the elongation at break of nanocellulose films. These structure-function relationships guided the fabrication of polyhydroxyalkanoates-doped MCNF toward sensing application, exhibiting a residual polarization strength of 0.49 mu C cm- 2, a coercive electric field of 378.5 kV cm- 1, and a maximum piezoelectric coefficient of 4.7 pC N-1. Overall, the structure-function-guided valorization of biomass revolutionized the MCNF fabrication, potentially contributing to a sustainable biomass-based economy.

关键词： Cellulose valorization Synergistic fractionation Nanoization Multifunctional nanocellulose film Structure-function relationship Lignin valorization

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Plant litter crust enhances nitrogen accumulation by regulating microbial diversity and urease activity in semi-arid sandy soils

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APPLIED SOIL ECOLOGY 2025年 205卷

作者： Cheng, Zhen Liu, Wei Li, Zhigang Carpio, Maria Jose Garcia-Gil, Juan Carlos Wang, Zhanjun Wu, Gao-Lin Northwest A&F Univ Inst Soil & Water Conservat State Key Lab Soil Eros & Dryland Farming Loess Pl Yangling 712100 Shaanxi Peoples R China Northwest A&F Univ Coll Nat Resources & Environm Yangling 712100 Shaanxi Peoples R China Ningxia Univ Coll Forestry & Prataculture Yinchuan 750021 Ningxia Peoples R China Chinese Acad Sci & Minist Water Resource Inst Soil & Water Conservat Yangling 712100 Shaanxi Peoples R China CSIC Inst Ciencias Agr Serrano 115 Bis Madrid 28006 Spain Ningxia Acad Agr & Forestry Sci Inst Forestry & Grassland Ecol Yinchuan 750002 Peoples R China

Plant litter plays a crucial role in regulating soil nitrogen (N) cycling in dryland ecosystems. However, the mechanisms by which plant litter crust drives microbial community composition to influence N levels in sandy soils remain unclear. In this study, we examined the effects of litter crust on sandy soil microhabitat characteristics (temperature, moisture, and porosity), microbial diversity and composition, urease activity, and soil N variables (total-N, nitrate-N, and ammonium-N) across different stages of litter crust development (including early-, mid-, and post-term) in a field setting. We found that litter crust promotes bacterial and fungal alpha diversity in sandy soils, leading to a shift in bacterial community composition from oligotrophs (i.e., Actinobacteria) to copiotrophs (i.e., Proteobacteria and Bacteroidetes), and a shift in fungal community composition dominance from Ascomycota to Basidiomycota. Litter crust enhances the complexity and stability of bacterial and fungal co-occurrence networks in sandy soils, especially in early- and mid-term stages of crust development. Additionally, litter crust increases nitrification (aerobic ammonia oxidation) and decreases denitrification (nitrate reduction) in these soils. Notably, the increase in soil moisture and urease activity, along with the decrease in soil temperature due to litter crust, effectively promotes N accumulation in sandy soils. Our results demonstrate that N levels during the litter crust period are mainly influenced by a combination of bacterial beta diversity and fungal alpha diversity at the 0-5 cm depth, and bacterial alpha diversity along with soil properties (i. e., soil variables and urease activity) at the 5-10 cm depth. Overall, our results reveal that litter crust contributes to N accumulation in sandy soils by regulating bacterial and fungal community composition and diversity, as well as by buffering soil temperature and soil moisture, and enhancing urease activity. These find

关键词： Litter crust Microbial network complexity Nitrogen cycling Bacteria Fungi Sandy soil

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