As an important component of automated guided vehicle (AGV) active safety systems, the active rollover prevention (ARP) control has been widely studied. In this paper, a fixed-time adaptive sliding mode (FTASM) contro...
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As an important component of automated guided vehicle (AGV) active safety systems, the active rollover prevention (ARP) control has been widely studied. In this paper, a fixed-time adaptive sliding mode (FTASM) control strategy based on nested adaptive law (NAL) and improved super-twisting observer (ISTO) is developed for the AGV. Firstly, the lateral and roll motion dynamics of AGV are established, and the ARP problem is transformed into the yaw stability control with constraints. Subsequently, a faster fixed-time stable system-based FTASM composite controller is proposed to guarantee a fixed and faster convergence time of the yaw rate tracking error, such that the rollover stability will reach a region of permissible risk. The adoption of NAL enables the adaptive controller to automatically search the minimum switching gain satisfying the reaching condition of sliding mode, thus the conservative assumption constraint of the disturbance upper bound is released. In addition, an ISTO is developed to estimate the unknown disturbance to further improve the control robustness and attenuate the control chattering. The closed-loop stability analysis is rigorously given by Lyapunov theory. Finally, the performance of the proposed control strategy is validated by hardware-in-loop simulations with Adams and Matlab software and an actual steer-by-wire plant.
Background Streptococcus pneumoniae (Spn) is a major causative agent of pneumonia, which can disseminate to the bloodstream and brain. Pneumonia remains a leading cause of death among children aged 1-59 months worldwi...
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Background Streptococcus pneumoniae (Spn) is a major causative agent of pneumonia, which can disseminate to the bloodstream and brain. Pneumonia remains a leading cause of death among children aged 1-59 months worldwide. This study aims to investigate the role of Kruppel-like factor 2 (KLF2) in lung injury caused by Spn in young mice. Methods Young mice were infected with Spn to induce pneumonia, and the bacterial load in the bronchoalveolar lavage fluid was quantified. KLF2 expression in lung tissues was analyzed using real-time quantitative polymerase chain reaction and Western blotting assays. Following KLF2 overexpression, lung tissues were assessed for lung wet-to-dry weight ratio and Myeloperoxidase activity. The effects of KLF2 on lung injury and inflammation were evaluated through hematoxylin and eosin staining and enzyme-linked immunosorbent assay. Chromatin immunoprecipitation and dual-luciferase assay were conducted to examine the binding of KLF2 to the promoter of microRNA (miR)-222-3p and cyclin-dependent kinase inhibitor 1B (CDKN1B), as well as the binding of miR-222-3p to CDKN1B. Levels of miR-222-3p and CDKN1B in lung tissues were also determined. Results In young mice with pneumonia, KLF2 and CDKN1B were downregulated, while miR-222-3p was upregulated in lung tissues. Overexpression of KLF2 reduced lung injury and inflammation, evidenced by decreased bacterial load, reduced lung injury, and lower levels of proinflammatory factors. Co-transfection of miR-222-3p-WT and oe-KLF2 significantly reduced luciferase activity, suggesting that KLF2 binds to the promoter of miR-222-3p and suppresses its expression. Transfection of CDKN1B-WT with miR-222-3p mimics significantly reduced luciferase activity, indicating that miR-222-3p binds to CDKN1B and downregulates its expression. Overexpression of miR-222-3p or downregulation of CDKN1B increased bacterial load in BALF, lung wet/dry weight ratio, MPO activity, and inflammation, thereby reversing the protective
Flavored fermented whipping cream has received particular attention. However, the effects of different fermentation methods on the quality and flavor of whipping cream remain elusive. This study characterized the flav...
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Flavored fermented whipping cream has received particular attention. However, the effects of different fermentation methods on the quality and flavor of whipping cream remain elusive. This study characterized the flavor, quality, and metabolites of whipping cream produced by different fermentation methods based on nontargeted metabolomics. The results showed that the quality, color, and flavor of fermented whipping cream were significantly improved. Notably, the GMF fermentation group had the highest variety and content of flavoring substances. A total of 729 shared metabolites were identified, mainly including glycerophospholipids (151, 20.71 %), fatty acyls (114, 15.64 %), organoacyls (89, 12.21 %). Whipping cream by the mixed bacteria fermentation contained lower lipids and higher flavor amino acids, while the contents of bitter peptides and some organic acids and their derivatives were significantly lower. The results of this study provide a valuable reference for enhancing the quality, flavor, flavor of whipping cream using mixed bacteria fermentation methods.
Objectives: A higher reperfusion grade after endovascular thrombectomy (EVT) is associated with a good prognosis. However, the effect of the number of retrievals has not yet been investigated in vertebrobasilar occlus...
Objectives: A higher reperfusion grade after endovascular thrombectomy (EVT) is associated with a good prognosis. However, the effect of the number of retrievals has not yet been investigated in vertebrobasilar occlusion (VBAO). Therefore, the aim of this study was to investigate whether to continue retrieval after early modified thrombolysis in cerebral infarction (mTICI) 2b to achieve a better reperfusion grade. MethodsWe retrospectively analyzed the data of patients who underwent EVT caused by VBAO in a multicenter registry dataset. Patients who underwent successful reperfusion were included (mTICI 2b/3). Regression models were used to analyze the correlation of different reperfusion grades stratified by the number of retrieval attempts with clinical prognosis and hemorrhage transition. Results: We included 432 patients: 34.5% (n = 149) had a final mTICI score of 2b and 65.5% (n = 283) had a final mTICI score of 3. Patients who obtained a mTICI of 3 after the first pass had significantly increased odds of having a good prognosis. As the number of passes increases, the chances of obtaining a good prognosis decreases. After three or more passes, the odds of achieving functional independence and favorable outcomes were comparable to those of the first mTICI 2b, regardless of the 90-day (OR 1.132 95% CI 0.367-3.487 p = 0.829;OR 1.070 95% CI 0.375-3.047 p = 0.900) or 1-year follow-up (OR 1.217 95% CI 0.407-3.637 p = 0.725;OR 1.068 95% CI 0.359-3.173 p = 0.906). Interpretation: Within two retrieval attempts, mTICI 3 was better than the first retrieval to mTICI 2b. After early mTICI 2b, each retrieval should be undertaken with caution to pursue a higher reperfusion grade.
As a typical antibiotic, tetracycline is ecotoxic and prone to bacterial resistance, producing superbugs and causing a public ecological crisis, thus raising the need to eliminate tetracycline from the aqueous environ...
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As a typical antibiotic, tetracycline is ecotoxic and prone to bacterial resistance, producing superbugs and causing a public ecological crisis, thus raising the need to eliminate tetracycline from the aqueous environment. In this work, magnetic catalyst Fe3O4@HKUST-1 was prepared for catalyzing the degradation of tetracycline by persulfate. X-ray diffraction, scanning electron microscopy, and vibrating sample magnetometry were used to characterize the catalyst, and the results show that the catalyst had good crystallinity and magnetic properties. Tetracycline removal in the Fe3O4@HKUST-1/persulfate system reached84.80%, and the catalyst was easily recovered from the solution due to its good magnetic properties. Mechanism analysis revealed that the non-radical pathway was the main degradation channel in the Fe-3-O-4@HKUST-1/persulfate system, and(1)O(2)was the main reactive oxygen species generated from O-v on the surface of the Fe3O4@HKUST-1 catalyst. Tetracycline degradation was achieved by hydroxylation, demethylation, decarbonylation, dehydroxylation and the cleavage of C-N bonds. This finding holds significant value in further comprehension of the catalytic activation mechanism of metal-organic frameworks derivatives on persulfate and provides novel ideas for efficient water treatment technology development.
This study aimed to investigate the effect of the combination of shaking and various anaerobic treatments on the aroma quality of gabaron oolong tea (GAOT) by chemical and sensory evaluation. The results showed that e...
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This study aimed to investigate the effect of the combination of shaking and various anaerobic treatments on the aroma quality of gabaron oolong tea (GAOT) by chemical and sensory evaluation. The results showed that elevated anaerobic treatment harmed GAOT aroma, emphasizing undesirable attributes such as earthy, fatty, etc. A total of 85 volatiles were identified by gas chromatography-ion mobility spectrometry (GC-IMS), and the relationship between aroma attributes and volatiles were revealed by PLS regression projection and correlation network. Hexanal and octanal at inappropriate concentrations were main causes to the earthy attribute, while nonanal exhibited a potential masking effect against unpleasant attributes. Addition experiments and ati plot analysis verified these associations. Furthermore, observing dynamic patterns of content changes of these three aldehydes in fresh leaves prior to tea thermal processing, providing references for future process optimization. These results provide a new direction for enhancing the quality of GAOT.
The rational and precise preparation of metal-organic framework (MOF)-derived carbon-based absorbers with a fine hollow structure and the tuning of their electromagnetic properties at low loading for synergistic optim...
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The rational and precise preparation of metal-organic framework (MOF)-derived carbon-based absorbers with a fine hollow structure and the tuning of their electromagnetic properties at low loading for synergistic optimization of impedance matching and high attenuation capacity for efficient utilization have become important challenges for lightweight electromagnetic wave absorption (EMWA). Herein, a hollow particle-assembled one-dimensional (1D) nanotube carbon matrix composite loaded with dispersed Co nanoparticles is fabricated by a two-step hollowing strategy of solvent-assisted ligand exchange (SALE) and a protected etching process, combined with a subsequently optimized pyrolysis. This novel hollow structure promotes multiple reflections and scattering of incident electromagnetic waves, optimizes impedance matching, and also greatly enhances the synergistic effect of multiple loss mechanisms, remarkably improving the electromagnetic characteristics. The results indicate that Co-ZIF-HPT-700 achieves a minimum reflection loss (RLmin) of -76.93 dB at 8.96 GHz with a fill rate of only 10 wt%. At the matched thicknesses of 2.12 and 2.96 mm, it realizes full-band absorption in Ku and X bands, respectively. This work provides novel ideas for the design of a new generation of ultra-lightweight EMWA materials.
Rapid road network expansion has heightened the importance of surface condition information for traffic accident prevention and route optimization. This article introduces a laser diode-based sensor that identifies se...
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Rapid road network expansion has heightened the importance of surface condition information for traffic accident prevention and route optimization. This article introduces a laser diode-based sensor that identifies seven surface conditions and accurately measure ice, water, and snow film thicknesses on roads. An optical module was developed to detect weak optical signals based on the characteristic absorption spectrum of the target surface. The module used three laser diodes (1310, 1440, and 1550 nm wavelengths) as light sources. Additionally, a road classification algorithm that is adaptable to foggy weather was developed using a multi-wavelength processing protocol. The sensor was subjected to numerous calibration and performance verification experiments. During thick foggy measurements, the processed spectra displayed a maximum variation of 2.372% across a 600 to 25,000 m visibility range with a relative standard deviation of only 0.328%. This demonstrated effective weakening of the effects of visibility variations. During winter field testing, the sensor classified road conditions effectively and accurately measured ice, snow, and water film thicknesses, with a correlation coefficient of 0.97444. The accuracy of the measurements was less than 0.5 mm. The sensor's effectiveness for long-term field-based road testing has been verified.
A new type of MnxCd1-xS p-n junction self-assembled by n-type twin-phase MnxCd1-xS (T-CdS-hosted MCS) and ptype MnxCd1-xS (alpha-MnS-hosted MCS) was fabricated through a convenient one-pot hydrothermal route. The phot...
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A new type of MnxCd1-xS p-n junction self-assembled by n-type twin-phase MnxCd1-xS (T-CdS-hosted MCS) and ptype MnxCd1-xS (alpha-MnS-hosted MCS) was fabricated through a convenient one-pot hydrothermal route. The photocatalytic HER performance of 0.5MCS (x = 0.5) was greatly improved on coupling with noble metal-free NiS cocatalyst. The H2-evolution rate of optimal 1.0 wt% NiS/0.5MCS reached 53.4 mmol center dot g-1 center dot h-1 under visible-light irradiation, almost 17.6 times higher than that of pristine T-CdS, which significantly exceeded that of 1.0 wt% Pt/0.5MCS (16.7 mmol center dot g-1 center dot h-1). The AQE of 1.0 wt% NiS/0.5MCS of was 22.49% at 420 nm. The possible photocatalytic mechanism was rationally put forward based on the current experimental results and band structure, revealing that the built-in electric field at the interface of MnxCd1-xS p-n junction as well as auxiliary catalytic effect of NiS effectively promoted the transfer and separation of the photogenerated electron- hole pairs, thus leading to the improvement of photocatalytic HER ability.
Epoxy resin (EP) is a versatile material widely employed in diverse fields such as electronic encapsulation, coatings, and adhesives. The optimization of flame-retardant, mechanical and interfacial properties in compo...
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Epoxy resin (EP) is a versatile material widely employed in diverse fields such as electronic encapsulation, coatings, and adhesives. The optimization of flame-retardant, mechanical and interfacial properties in composites through material modification and compounding represents a prominent research focus within the field of EP. This study presents a novel approach by synthesizing MOF-derived nickel phyllosilicate (K-NiPS) and compounding it with 9,10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide (DOPO) into the EP matrix. The incorporation of 5 wt% total K-NiPS and DOPO, with a mass ratio of 2:3, achieves a UL-94 V-0 rating and enhances the limiting oxygen index from 23.5 to 28.8 %. This combination also reduced the peak heat release rate, peak smoke release rate, and total smoke release by 44.6 %, 53.6 %, and 37.8 % respectively. Besides, the interface optimization effect of K-NiPS in collaboration with DOPO improved the tensile strength of EP/ 2K-NiPS/3DOPO from 77.5 MPa to 94.3 MPa, and the wear rate was only 1.25 x 10-5 mm3/(N & sdot;m), which is 82.2 % lower than that of pure EP. This study will pave the way for the applied interface design of multifunctional EP.
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