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Annual International Conference of the IEEE Engineering in Medicine and Biology Society

作者： M. A. Santiago-Cordoba P. R. Romano A. MacKay M. C. Demirel Chemistry Department Pennsylvania State University Microbiology and Immunology Drexel Institute for Biotechnology and Virology Research and The Institute for Hepatitis and Virus Research Materials Research Institute and Department of Engineering Science Pennsylvania State University

ISBN: (纸本)9781424441211

Highly sensitive and selective biomarker detection is required for early detection of hepatocellular carcinoma (HCC). Disease progression has been shown to correlate with specific fucosylation of a validated HCC serum glycoprotein biomarker, alpha-fetoprotein (AFP) Carbohydrate binding proteins, such as lectins, can be used as diagnostic indicators for monitoring glycosylation changes during disease progression in hepatitis B virus (HBV) or hepatitis C virus (HCV) infected patients. We prepared surface-enhanced Raman spectroscopy (SERS) substrates, which provide controllable, well-organized nanoparticles on the surface, for the analysis of a fucose binding lectin AAL. The SERS based assay provides fast (<10 s), and reproducible (<5% variation) detection.

关键词： Raman Lectins Biological Markers Disease Progression Hepatocellular Cancer alpha-Fetoproteins Early Diagnosis diagnostic indicator Hepatitis B virus surface enhanced Raman scattering human-centered computing Hepatitis C virus

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A human-centered Semantic Service Platform for the Digital Ecosystems Environment

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WORLD WIDE WEB-INTERNET AND WEB INFORMATION SYSTEMS 2010年第1-2期13卷 75-103页

作者： Dong, Hai Hussain, Farookh Khadeer Chang, Elizabeth Curtin Univ Technol Digital Ecosyst & Business Intelligence Inst Bentley WA 6102 Australia

Digital Ecosystems (DEST) have emerged with the purpose of enhancing communications among small and medium enterprises (SMEs) within the worldwide Business Ecosystem. However, because of the diversity and heterogeneity of the services in the DEST environment, existing commercial products or research outputs cannot be directly applied to this field so as to fulfill the requirements of SMEs. human-centered computing has been applied to many areas, such as social classification, community-based ontology evolution, and more importantly, human-centered systems. In this paper, we propose a framework for a human-centered semantic service platform, in order to address the issue in the DEST environment. This framework incorporates the features of human-centered metadata publishing, maintenance and clustering, community-based ontology revolution and human-centered service retrieval, evaluation and ranking. To thoroughly validate the framework, we implement a prototype in the transport service domain, and conduct a series of evaluation experiments on the basis of this prototype.

关键词： digital ecosystems (abbreviated as DEST) human-centered computing human-centered systems ontology revolution QoS evaluation service platform

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human-Agent Collaboration for Time-Stressed Multicontext Decision Making

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IEEE TRANSACTIONS ON SYSTEMS MAN AND CYBERNETICS PART A-SYSTEMS AND humanS 2010年第2期40卷 306-320页

作者： Fan, Xiaocong McNeese, Michael Sun, Bingjun Hanratty, Timothy Allender, Laurel Yen, John Penn State Univ University Pk PA 16802 USA Telenav Inc Sunnyvale CA 94086 USA USA Res Lab Aberdeen Proving Ground MD 21005 USA

Multicontext team decision making under time stress is an extremely challenging issue faced by various real-world application domains. In this paper, we employ an experience-based cognitive agent architecture (called R-CAST) to address the informational challenges associated with military command and control (C-2) decision-making teams, the performance of which can be significantly affected by dynamic context switching and tasking complexities. Using context switching frequency and task complexity as two factors, we conducted an experiment to evaluate whether the use of R-CAST agents as teammates and decision aids can benefit C-2 decision-making teams. Members from a U. S. Army Reserve Officer Training Corps organization were randomly recruited as human participants. They were grouped into ten human-human teams, each composed of two participants, and ten human-agent teams, each composed of one participant and two R-CAST agents, as teammates and decision aids. The statistical inference of experimental results indicates that R-CAST agents can significantly improve the performance of C-2 teams in multi-context decision making under varying time-stressed situations.

关键词： Cognitive agents context switching human-centered computing naturalistic decision making

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A Low-Power, Battery-Free Tag for Body Sensor Networks

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IEEE PERVASIVE computing 2010年第1期9卷 71-77页

作者： Mandal, Soumyajit Turicchia, Lorenzo Sarpeshkar, Rahul MIT Dept Elect Engn & Comp Sci Cambridge MA 02139 USA

The authors describe a low-power, battery-free tag for use in pervasive sensing applications such as wearable patient-monitoring systems and body sensor networks. The tag consists of a custom integrated circuit, an antenna for RF energy harvesting, and several sensors for monitoring important physiological parameters and generating alarms when necessary. They also describe experimental results with phonocardiogram and photoplethysmogram signals and demonstrate tag localization within 0.6 m by using an audio localization scheme.

关键词： Microphones Heart Radio frequency Monitoring Skin Biomedical monitoring Wrist human-centered computing body sensor networks localization wireless monitoring wearable sensors energy harvesting pervasive monitoring body area networks

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Easing the Smart Home: A rule-based language and multi-agent structure for end user development in Intelligent Environments

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JOURNAL OF AMBIENT INTELLIGENCE AND SMART ENVIRONMENTS 2010年第4期2卷 437-438页

作者： Garcia-Herranz, Manuel Alaman, Xavier Haya, Pablo A. Univ Autonoma Madrid Campus Cantoblanco Madrid 28039 Spain

The present paper summarizes the Phd Dissertation of Manuel Garcia-Herranz [1] including the oral defense's.

关键词： Ubiquitous computing human-centered computing rule-based processing command and control

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Context-Awareness Handoff Planning in Heterogeneous Wireless Networks

Context-Awareness Handoff Planning in Heterogeneous Wireless...

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7th International Conference on Autonomic and Trusted computing

作者： Huang, Hsiao-Yun Wang, Chiung-Ying Hwang, Ren-Hung Natl Chung Cheng Univ Dept Comp Sci & Informat Engn Taipei Taiwan Transworld Univ Dept Informat & Management Taipei Taiwan

ISBN: (纸本)9783642163548

This paper addresses a context-awareness handoff planning mechanism in heterogeneous wireless networks for seamless ubiquitous access. The proliferation of digital devices with communication capability heralds the era of ubiquitous computing, as predicted by Mark Weiser. Mobile devices with multi-mode interfaces can access heterogeneous wireless networks, such as wireless local area network (WLAN), worldwide interoperability for microwave access (WiMAX) network and third generation (3G) network. In heterogeneous wireless networks, different network provides different network capability, transmission range, data rate, access cost, security policy and quality of service. Therefore, a ubiquitous access aims to provide users intelligent human-centric context-aware handoff mechanism in heterogeneous wireless networks at anytime anywhere is gradually become an important issue. Optimal handoff planning in heterogeneous wireless networks considers the needs of users, accessing service and the surrounding context. However, most of existing handoff mechanisms only considered few contexts that lead to not able to select the most suitable network for individual user. In this paper, we propose a human-centric context-aware solution to access most appropriate network that satisfies individual user's requirement, fulfills seamless data transmission and reduces handoff delay. We develop two integrated approaches for context-awareness handoff planning mechanisms, namely MADM approach and GA approach. The MADM approach contains initial process and decision process. Initial process weights context by Analytic Hierarchy Process (AHP) method while decision process selects the most appropriate network by Technique for Order Preference by Similarity to Ideal Solution (TOPSIS). The GA approach uses Genetic Algorithm to minimize handoff under given QoS constraints. Performance of proposed mechanisms is evaluated under different services with different QoS considerations. Our simulation resu

关键词： Ubiquitous computing human-centered computing context-awareness MADM genetic algorithm handoff heterogeneous wireless networks

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The Impact of a Mixed Reality Display Configuration on User Behavior with a Virtual human

The Impact of a Mixed Reality Display Configuration on User ...

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10th International Conference on Intelligent Virtual Agents (IVA)

作者： Johnsen, Kyle Beck, Diane Lok, Benjamin Univ Georgia Fac Engn Athens GA 30602 USA Univ Florida Coll Pharm Gainesville FL USA Univ Florida Gainesville FL 32611 USA

ISBN: (纸本)9783642158919

Understanding the human-computer interface factors that influence users' behavior with virtual humans will enable more effective human-virtual human encounters. This paper presents experimental evidence that using a mixed reality display configuration can result in significantly different behavior with a virtual human along important social dimensions. The social dimensions we focused on were engagement, empathy, pleasantness, and naturalness. To understand how these social constructs could be influenced by display configuration, we video recorded the verbal and non-verbal response behavior to stimuli from a virtual human under two fundamentally different display configurations. One configuration presented the virtual human at life-size and was embedded into the environment, and the other presented the virtual human using a typical desktop configuration. We took multiple independent measures of participant response behavior using a video coding instrument. Analysis of these measures demonstrates that display configuration was a statistically significant multivariate factor along all dimensions.

关键词： virtual humans embodied agents human-centered computing medicine displays

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Gestures for Large Display Control

Gestures for Large Display Control

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8th International Gesture Workshop

作者： Fikkert, Wim van der Vet, Paul van der Veer, Gerrit Nijholt, Anton Univ Twente NL-7500 AE Enschede Netherlands

ISBN: (纸本)9783642125522

The hands are highly suited to interact with large public displays. It is, however, not apparent which gestures come naturally for easy and robust use of the interface. We first explored how uninstructed users gesture when asked to perform basic tasks. Our subjects gestured with great similarity and readily produced gestures they had seen before;not necessarily in a human-computer interface. In a second investigation these and other gestures were rated by a hundred subjects. A gesture set for explicit command-giving to large displays emerged from these ratings. It is notable that for a selection task, tapping the index finger in mid-air, like with a traditional mouse, scored highest by far. It seems that the mouse has become a metaphor in everyday life.

关键词： human-centered computing user interfaces input devices and strategies intuitive hand gestures large display interaction

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SIREN: Mediated Informal Communication for Serendipity

SIREN: Mediated Informal Communication for Serendipity

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4th International Conference on Mobile Ubiquitous computing, Systems, Services and Technologies (UBICOMM)

作者： Batalas, Nikolaos Bruikman, Hester Turzynska, Dominika Vakili, Vanesa Voynarovskaya, Natalia Markopoulos, Panos Eindhoven Univ Technol Dept Ind Design Dolech 2 NL-5612 AZ Eindhoven Netherlands

ISBN: (纸本)9781612081007

The process of education and innovation often involves individuals, whose expertise lies in diverse fields. Informal communication amongst them can prove to be invaluable towards their collaboration, but rarely does it extend beyond one's already established social circle. This paper proposes SIREN, a system, which makes use of sensor nodes to detect encounters between colleagues in their workplace, as they undertake their daily tasks and spreads information virally from one to another. The aim is to introduce a channel of informal communication that is not disruptive to their routine. We developed a system prototype and conducted a field test to detemine whether the premise of encounter-based information sharing offers any added value over information sharing without discrimenation, amongst users in the same work setting. The results indicate that SIREN can help break down barriers and promote subsequent direct communication between users.

关键词： human-centered computing wireless sensor networks serendipity

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Ubiquitous Mining with Interactive Data Mining Agents

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Journal of Computer Science & Technology 2009年第6期24卷 1018-1027页

作者：吴信东朱兴全陈琪君王飞跃 School of Computer Science and Information Engineering Hefei University of Technology Department of Computer Science University of Vermont Faculty of Engineering and Information Technology University of Technology Institute of Automation Chinese Academy of Sciences

Due to the increasing availability and sophistication of data recording techniques, multiple information sources and distributed computing are becoming the important trends of modern information systems. Many applications such as security informatics and social computing require a ubiquitous data analysis platform so that decisions can be made rapidly under distributed and dynamic system environments. Although data mining has now been popularly used to achieve such goals, building a data mining system is, however, a nontrivial task, which may require a complete understanding on numerous data mining techniques as well as solid programming skills. Employing agent techniques for data analysis thus becomes increasingly important, especially for users not familiar with engineering and computational sciences, to implement an effective ubiquitous mining platform. Such data mining agents should, in practice, be intelligent, complete, and compact. In this paper, we present an interactive data mining agent - OIDM （online interactive data mining）, which provides three categories （classification, association analysis, and clustering） of data mining tools, and interacts with the user to facilitate the mining process. The interactive mining is accomplished through interviewing the user about the data mining task to gain efficient and intelligent data mining control. OIDM can help users find appropriate mining algorithms, refine and compare the mining process, and finally achieve the best mining results. Such interactive data mining agent techniques provide alternative solutions to rapidly deploy data mining techniques to broader areas of data intelligence and knowledge informaties.

关键词： information systems human-centered computing data mining intelligent agents

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