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ACM SIGCHI Conference on human Factors in computing Systems (CHI)

作者： Soden, Robert Sprain, Leah Palen, Leysia Univ Colorado Dept Comp Sci Boulder CO 80309 USA Univ Colorado Dept Commun Boulder CO 80309 USA Univ Colorado Dept Informat Sci Boulder CO 80309 USA

ISBN: (纸本)9781450346559

This paper reports on two years of ethnographic observation of the science and politics of flood risk in Colorado, as well as design research that examines citizen interaction with expert knowledge about flooding in the region. We argue that the 100-year floodplain standard that inform maps produced by the United States Federal Emergency Management Agency (FEMA)'s National Floodplain Insurance Program (NFIP) represent a problematic form of discursive closure of scientific understanding of flood hazard. We show that in order to meet the requirements of the NFIP, this standard acts as a closure that conveys a certainty that the underlying science does not warrant and foreshortens dialogue on disaster risk and public understanding of flood hazard. Engaging with literature in science and technology studies and human-centered computing, we investigate design opportunities for resisting closure and supporting public formation through encounters with the uncertainty and complexities of risk information.

关键词： Flood risk Design human-centered computing Public engagement Science and technology studies

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Trends in Incidence of Two Major Subtypes of Liver and Bile Duct Cancer: Hepatocellular Carcinoma and Cholangiocarcinoma in Songkhla, Southern Thailand, 1989-2030

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JOURNAL OF CANCER EPIDEMIOLOGY 2018年第1期2018卷 8267059-8267059页

作者： Yeesoonsang, Seesai McNeil, Edward Virani, Shama Bilheem, Surichai Pittayawonganon, Chakrarat Jiraphongsa, Chuleeporn Sriplung, Hutcha Prince Songkla Univ Fac Med Epidemiol Unit Hat Yai Thailand Minist Publ Hlth Off Permanent Secretary Nonthaburi Thailand Minist Publ Hlth Thailand MOPH US CDC Collaborat TUC Nonthaburi Thailand

Background. The incidence of liver and bile duct cancer continues to rise, especially in Thailand. We aimed to project the trends in incidence of this rare but lethal cancer in southern Thailand in order to determine its future disease burden. Methods. Gender-specific trends in age-standardized incidence rates per 100,000 person-years for hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA) cases in Songkhla province of southern Thailand diagnosed between 1989 and 2013 were estimated and projected up to year 2030 using three different modeling techniques: a joinpoint model, an age-period-cohort model, and a modified age-period-cohort model. Results. Of 2,676 liver and bile duct (LBD) cancer cases identified, 73% were males, 51% were aged between 50 and 69 years, and HCC (44.4%) was slightly more common than CCA (38.1%). The models all predicted an increase in the incidence rate of CCA up to 2025 for both sexes whereas the incidence of HCC is expected to decrease among males and stabilize among females. The incidence rates of HCC and CCA among males in 2030 could reach 6.7 and 9.4 per 100,000 person-years, respectively, whereas the expected rates of HCC and CCA among females are expected to be around 1.5 and 3.9 per 100,000 person-years, respectively. Conclusions. The incidence of cholangiocarcinoma is expected to increase in Songkhla and will contribute a larger proportion of LBD cancers in the future. Future public health efforts and research studies should focus on this increasing trend.

关键词： Thailand Incidence Liver human-centered computing Cholangiocarcinoma Bile Duct Cancer

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Designing Intentional Impossible Spaces in Virtual Reality Narratives: A Case Study 19

Designing Intentional Impossible Spaces in Virtual Reality N...

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19th IEEE Virtual Reality Conference (VR)

作者： Fisher, Joshua A. Garg, Amit Singh, Karan Pratap Wang, Wesley Georgia Inst Technol Atlanta GA 30332 USA

ISBN: (纸本)9781509066476

Natural movement and locomotion in Virtual Environments (VE) is constrained by the user's immediate physical space. To overcome this obstacle, researchers have established the use of impossible spaces. This work illustrates how impossible spaces can be utilized to enhance the aesthetics of, and presence within, an interactive narrative. This is done by creating impossible spaces with a narrative intent. First, locomotion and impossible spaces in VR are surveyed;second, the benefits of using intentional impossible spaces from a narrative design perspective is presented;third, a VR narrative called Ares is put forth as a prototype;and fourth, a user study is explored. Impossible spaces with a narrative intent intertwines narratology with the world's aesthetics to enhance dramatic agency.

关键词： human-centered computing Virtual Reality Interaction design theory design

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Liver Transplantation for Hepatocellular Carcinoma: "Experience of Memorial Sisli Hospital"

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JOURNAL OF GASTROINTESTINAL CANCER 2017年第3期48卷 272-273页

作者： Acarli, Koray Mem Sisli Hosp Istanbul Turkey

Hepatocellular carcinoma (HCC) is the most common primary tumor of the liver and is considered an aggressive tumor with mean survival estimated between 6 and 20 months. Hepatic resection is the treatment of choice in patients with HCC in noncirrhotic livers. Some large series demonstrated 5-year survival rates between 30 and 50% after hepatic resection [1]. It is also well known that HCC occurs in chronically diseased livers in about >90% cases. Impairment of liver function and existence of portal hypertension make a safe liver resection impossible in most of the patients, and therefore, the resectability is still very low (5 to 10%). A high tumor recurrence, either as intrahepatic metastases or as development of de novo tumors on remaining cirrhotic liver, is not uncommon. On the other hand, liver transplantation (OLT) appears to be the best treatment for HCC while offering the best oncological resection and also correction of liver function. Early experience with OLT for HCC resulted in poor post-transplant survival and high recurrence rates which believed are due to suboptimal patient selection [2].

关键词： Liver Survival Rate Recurrent Neoplasm Primary Neoplasm Liver Neoplasms Hepatectomy liver function Portal Hypertension Patient Selection human-centered computing Optical Line Terminal Repetition rate

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Radiological Response to the Locoregional Treatment in Hepatocellular Carcinoma: RECIST, mRECIST, and Others

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JOURNAL OF GASTROINTESTINAL CANCER 2017年第3期48卷 282-285页

作者： Kantarci, Mecit Pirimoglu, Berhan Ataturk Univ Fac Med Dept Radiol TR-25040 Erzurum Turkey

Introduction: Hepatocellular carcinoma (HCC) is the sixth most common tumor worldwide [1]. Locoregional treatment choices for HCC include molecular-targeted chemotherapy, yttrium-90 radioembolization, and interventional radiological methods including transcatheter arterial chemoembolization (TACE) and radiofrequency ablation (RFA) [2, 3]. Imaging has a very important role in the management of HCC and the efficacy of treatment is usually monitored and evaluated radiologically. Response to therapy has been evaluated by morphologic methods using different criteria such as the World Health Organization (WHO) criteria or the Response Evaluation Criteria in Solid Tumors (RECIST) in treatment (Table 1). However, the development of advanced therapies has required novel methods for evaluating response to treatment. This need has led to development of tumor- or therapy-specific guidelines such as the modified computed tomography (CT) Response Evaluation (Choi) Criteria for gastrointestinal stro-mal tumors, the European Association for Study of the Liver (EASL) criteria, and modified RECIST (mRECIST) (Table 2) for HCC [4-7]. mRECIST based on changes in viable tumor has become the guideline for HCC being treated with targeted treatments. Imaging for tumor response evaluation has evolved over the past few years as a result of advances in imaging techniques and new available imaging parameters including new functional advanced imaging methods, In this review, we discuss radiological response methods to evaluate tumor response in the management of HCC.

关键词： Imaging Hepatocellular Cancer World Health Organisation Tumours evaluation criterion Treatment Response Determinations human-centered computing

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Spontaneous Regression of Hepatocellular Carcinoma-a Case Report

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JOURNAL OF GASTROINTESTINAL CANCER 2017年第2期48卷 194-197页

作者： Alam, Mohamed Aftab Das, Debasish Kettering & Dist Gen Hosp Dept Gastroenterol & Hepatol Kettering England

Introduction: Hepatocellular carcinoma (HCC) is the fifth most common cancer in men and the second biggest cause of cancer mortality in the world [1]. Its incidence is particularly high in Asia and South Africa. Spontaneous regression (SR) in cancer has been recognised as a phenomenon for a long time, and documentations exist in medieval texts but formal definition as \"the partial or complete disappearance of a malignant tumour in the absence of treatment or in the presence of therapy considered inadequate to exert a significant influence on the disease\" was composed by Dr. Tilden Everson and Dr. Warren Cole in the 1960s [2]. SR incidence has been variously estimated to be 1 in 60,000 to 140,000 cases of cancer, although it is practically very difficult to derive evidence-based figures [3]. Approximately 50 % of the reported cases are renal cell carcinoma, melanoma and neuroblastoma. Evidence of SR in HCC is much rarer, and less than 90 cases are reported, mainly as case reports or small case series from Far-East particularly from Japan, Korea and China. The exact mechanism underlying SR is unknown, although possible vascular and immunologic phenomenon has been proposed. We report a case of 65-year-old man with HCC whose liver lesion and peri-aortic lymphadenopathy regressed along with normalisation of a significantly raised serum alfa-fetoprotein (AFP) over a period of six months without any medical or surgical intervention followed by resurgence of the lesion and progressive rise in alfa-fetoprotein over the next several months until the death of the patient.

关键词： hepatic damage normalisation Malignancy resurgence human-centered computing cancer mortality

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Cuddly User Interfaces

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COMPUTER 2016年第7期49卷 14-19页

作者： Sugiura, Yuta Igarashi, Takeo Inami, Masahiko Keio Univ Fac Sci & Technol Tokyo 108 Japan Univ Tokyo Grad Sch Informat Sci & Technol Tokyo 1138654 Japan

Cuddly User Interfaces employ soft objects as interfaces between people and smart systems. They can contribute to the realization of ubiquitous computing because soft objects are familiar to us and induce a low psycho... 详细信息

关键词： User interfaces Computer interfaces Monitoring Robots Optical fiber sensors Ubiquitous computing human-computer interaction robotics Cuddly User Interfaces Cuddly UIs user interfaces human-computer interaction human-centered computing ubiquitous computing FuwaFuwa Graffiti Fur PINOKY

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Challenging the principle of utility as a barrier for wider use of liver transplantation for hepatocellular cancer

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ANNALS OF SURGICAL ONCOLOGY 2017年第11期24卷 3188-3195页

作者： Grat, Michal Stypulkowski, Jan Patkowski, Waldemar Wronka, Karolina M. Bik, Emil Krasnodebski, Maciej Masior, Lukasz Lewandowski, Zbigniew Wasilewicz, Michal Grat, Karolina Krawczyk, Marek Zieniewicz, Krzysztof Med Univ Warsaw Dept Gen Transplant & Liver Surg Warsaw Poland Med Univ Warsaw Dept Epidemiol Warsaw Poland Med Univ Warsaw Dept Gen Transplant & Liver Surg Hepatol & Internal Med Unit Warsaw Poland Med Univ Warsaw Dept Clin Radiol 2 Warsaw Poland

Although transplant benefit appears superior for patients with advanced hepatocellular cancer (HCC), liver transplantation remains limited to selected low-risk HCC patients to keep their outcomes similar to heterogeneous group of non-HCC patients. The purpose of this study was to assess the rationale for current policy of restricting access to liver transplantation to minority of HCC patients based on utility principle. This retrospective cohort study comprised 1246 liver transplant recipients, including 206 HCC and 1040 non-HCC patients. Patient survival was the primary outcome measure. Patients with HCC and benign diseases were divided into low-, moderate-, and high-risk subgroups basing on independent risk factors for disease-free survival and model for end-stage liver disease (MELD) score (< 30, 30-40, > 40), respectively. MELD (p < 0.001) and presence of HCC (p = 0.008) were independent risk factors for early and late mortality, respectively. Total tumor volume (p = 0.008) and alpha-fetoprotein (p = 0.013) were independent predictors of recurrence and mortality used for division of HCC patients into low-, moderate-, and high-risk subgroups, with disease-free survival rates of 74.9% (5 years), 51.7% (5 years), and 8.0% (3 years), respectively (p < 0.001). There were no differences in 5-year overall survival between low-risk HCC (74.9%) and non-HCC (81.9%) patients (p = 0.210), moderate-risk HCC (63.3%) and non-HCC (68.0%) patients (p = 0.372), and high-risk HCC (55.0%) and non-HCC (56.0%) patients (p = 0.559). The principle of utility is unequally applied for restriction of access to liver transplantation for HCC patients. The results provide rationale for discussion on reinitiation of liver transplantation for advanced HCCs.

关键词： Hepatocellular Cancer Risk Factors Liver Transplantation Disease-Free Survival human-centered computing patient history of liver transplantation Patients

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Evaluating Existing Strategies to Limit Video Game Playing Time

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IEEE COMPUTER GRAPHICS AND APPLICATIONS 2016年第2期36卷 47-57页

作者： Davies, Bryan Blake, Edwin Univ Cape Town ZA-7700 Rondebosch South Africa Univ Cape Town Comp Sci ZA-7700 Rondebosch South Africa

Public concern surrounding the effects video games have on players has inspired a large body of research, and policy makers in China and South Korea have even mandated systems that limit the amount of time players spend in game. The authors present an experiment that evaluates the effectiveness of such policies. They show that forcibly removing players from the game environment causes distress, potentially removing some of the benefits that games provide and producing a desire for more game time. They also show that, with an understanding of player psychology, playtime can be manipulated without significantly changing the user experience or negating the positive effects of video games.

关键词： computer graphics Entertainment industry Games human factors human-centered computing Psychology software psychology Video games Visual computing

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Programmers Are Users Too: human-centered Methods for Improving Programming Tools

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COMPUTER 2016年第7期49卷 44-52页

作者： Myers, Brad A. Ko, Andrew J. LaToza, Thomas D. Yoon, YoungSeok Carnegie Mellon Univ Human Comp Interact Inst Sch Comp Sci Pittsburgh PA 15213 USA Univ Washington Informat Sch Seattle WA 98195 USA Univ Washington Comp Sci & Engn Dept Seattle WA 98195 USA George Mason Univ Comp Sci Volgenau Sch Engn Fairfax VA 22030 USA Google Mountain View CA USA

human-centered methods can help researchers better understand and meet programmers’ needs. Because programming is a human activity, many of these methods can be used without change. However, some programmer needs require new methods, which can also be applied to domains other than software engineering. This article features five Web extras. The video at https://***/4PH9-qi-yTQ demonstrates Azurite, an Eclipse plug-in with a selective undo feature that lets programmers more easily backtrack their code. The video at https://***/gOSlR62-rd8 describes Graphite, an Eclipse plug-in offering active code completion, a simple but powerful technique that integrates useful code-generation tools directly into the editor. The video at https://***/zyrqcYxqDtI describes HANDS, a new programming system that emphasizes usability by building on children’s and beginning programmers’ natural problem-solving tendencies. The video extra at https://***/80EctbI7PFc describes Whyline, a debugging tool that lets developers ask questions about their program’s output and behavior. The video at https://***/3L4MK2dG_6k demonstrates the prototype for Whyline, a debugging tool that lets developers pose questions about their program’s output.

关键词： Java program debugging software tools user centred design Azurite Eclipse plug-in Graphite HANDS Whyline active code completion debugging tool human activity human-centered methods natural problem-solving tendencies programming tools software engineering undo feature Data mining human computer interaction human-centered computing human-computer interaction Natural language processing Programming Software engineering A/B testing HCI contextual inquiry data mining end-user software engineering evaluation studies exploratory lab studies human-centered computing human-computer interaction log analysis natural-programming elicitation rapid prototyping software development software engineering software psychology studies of program constructs think-aloud usability evaluation user interfaces

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