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检索条件"主题词=Human-centered computing"
2475 条 记 录,以下是281-290 订阅
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Serum DKK1 as a protein biomarker for the diagnosis of hepatocellular carcinoma: a large-scale, multicentre study
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LANCET ONCOLOGY 2012年 第8期13卷 817-826页
作者: Shen, Qiujin Fan, Jia Yang, Xin-Rong Tan, Yexiong Zhao, Weifeng Xu, Yang Wang, Ning Niu, Yongdong Wu, Zheng Zhou, Jian Qiu, Shuang-Jian Shi, Ying-Hong Yu, Bin Tang, Ning Chu, Wei Wang, Min Wu, Jinhua Zhang, Zhigang Yang, Shengli Gu, Jianren Wang, Hongyang Qin, Wenxin Shanghai Jiao Tong Univ State Key Lab Oncogenes & Related Genes Shanghai Canc Inst Renji HospSch Med Shanghai 200032 Peoples R China Fudan Univ Inst Biomed Sci Shanghai 200433 Peoples R China Second Mil Med Univ Eastern Hepatobiliary Surg Hosp Shanghai Peoples R China Soochow Univ Affiliated Hosp 1 Dept Infect Dis Suzhou Peoples R China
Background Hepatocellular carcinoma (HCC) is prevalent worldwide and improvements in timely and effective diagnosis are needed. We assessed whether measurement of Dickkopf-1 (DKK1) in serum could improve diagnostic ac... 详细信息
来源: 评论
Optimal Measurement Modality and Method for Evaluation of Responses to Transarterial Chemoembolization of Hepatocellular Carcinoma Based on Enhancement Criteria
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JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY 2013年 第3期24卷 316-325页
作者: Shim, Ju Hyun Han, Seungbong Shin, Yong Moon Yu, Eunsil Park, Wonhyeong Kim, Kang Mo Lim, Young-Suk Lee, Han Chu Univ Ulsan Coll Med Asan Med Ctr Dept GastroenterolAsan Liver Ctr Seoul 138736 South Korea Univ Ulsan Coll Med Asan Med Ctr Dept RadiolAsan Liver Ctr Seoul 138736 South Korea Univ Ulsan Coll Med Asan Med Ctr Dept PatholAsan Liver Ctr Seoul 138736 South Korea Univ Ulsan Coll Med Asan Med Ctr Dept Biostat Seoul 138736 South Korea
Purpose: To determine the usefulness of enhancement by iodized oil deposits on computed tomography (CT) following transarterial chemoembolization for hepatocellular carcinoma (HCC), and to compare the reliability of s... 详细信息
来源: 评论
Contrast-enhanced ultrasound for characterisation of hepatic lesions appearing non-hypervascular on CT in chronic liver diseases
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BRITISH JOURNAL OF RADIOLOGY 2012年 第1012期85卷 351-357页
作者: Maruyama, H. Takahashi, M. Ishibashi, H. Yoshikawa, M. Yokosuka, O. Chiba Univ Grad Sch Med Dept Med & Clin Oncol Chuou ku Chiba 2608670 Japan
Objectives: The purpose of this prospective study was to elucidate the efficacy of using contrast-enhanced ultrasound to characterise focal hepatic lesions appearing non-hypervascular on contrast-enhanced CT in chroni... 详细信息
来源: 评论
Effects of low concentrations of Regorafenib and Sorafenib on human HCC cell AFP, migration, invasion, and growth in vitro
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JOURNAL OF CELLULAR PHYSIOLOGY 2013年 第6期228卷 1344-1350页
作者: Carr, Brian I. D'Alessandro, Rosalba Refolo, Maria G. Iacovazzi, Palma A. Lippolis, Catia Messa, Caterina Cavallini, Aldo Correale, Mario Di Carlo, Antonio IRCCS S de Bellis Natl Inst Digest Dis Biochem Lab I-70013 Castellana Grotte BA Italy IRCCS S de Bellis Natl Inst Digest Dis Clin Pathol Lab I-70013 Castellana Grotte BA Italy
Sorafenib was shown in clinical trial to enhance survival in hepatocellular carcinoma (HCC) patients, but with minimal tumor shrinkage. To correlate several indices of HCC growth at various drug concentrations, HCC ce... 详细信息
来源: 评论
EASL-EORTC Clinical Practice Guidelines: Management of hepatocellular carcinoma
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EUROPEAN JOURNAL OF CANCER 2012年 第5期48卷 599-641页
作者: European Assoc Study Liver EASL Off CH-1205 Geneva Switzerland
EASL-EORTC Clinical Practice Guidelines (CPG) on the management of hepatocellular carcinoma (HCC) define the use of surveillance, diagnosis and therapeutic strategies recommended for patients with this type of cancer.... 详细信息
来源: 评论
Comparative Analysis of the Safety and Efficacy of Transcatheter Arterial Chemoembolization and Yttrium-90 Radioembolization in Patients with Unresectable Hepatocellular Carcinoma
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JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY 2011年 第12期22卷 1697-1705页
作者: Lance, Craig McLennan, Gordon Obuchowski, Nancy Cheah, Grace Levitin, Abraham Sands, Mark Spain, James Srinivas, Shyam Shrikanthan, Sankaran Aucejo, Federico N. Kim, Richard Menon, K. V. Narayanan Cleveland Clin Fdn Inst Digest Dis Imaging Inst Cleveland OH 44195 USA Cleveland Clin Fdn Inst Digest Dis Dept Transplant Surg Cleveland OH 44195 USA Case Western Reserve Univ Sch Med Cleveland OH USA Cleveland Clin Fdn Inst Digest Dis Div Vasc & Intervent Radiol Cleveland OH 44195 USA Cleveland Clin Fdn Inst Digest Dis Dept Quantitat Hlth Sci Cleveland OH 44195 USA
Purpose: To compare retrospectively the safety and efficacy of yttrium-90 ((90)Y) radioembolization with the safety and efficacy of chemoembolization in patients with unresectable hepatocellular carcinoma (HCC). Mater... 详细信息
来源: 评论
Predictors for Microinvasion of Small Hepatocellular Carcinoma ≤2 cm
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ANNALS OF SURGICAL ONCOLOGY 2012年 第6期19卷 2027-2034页
作者: Yamashita, Yo-ichi Tsuijita, Eiji Takeishi, Kazuki Fujiwara, Megumu Kira, Shinsuke Mori, Masaki Aishima, Shinichi Taketomi, Akinobu Shirabe, Ken Ishida, Terutoshi Maehara, Yoshihiko Hiroshima Red Cross Hosp Dept Surg Hiroshima Japan Atom Bomb Survivors Hosp Hiroshima Japan Kyushu Univ Grad Sch Med Sci Dept Surg & Sci Fukuoka 812 Japan Hiroshima Red Cross Hosp Dept Pathol Hiroshima Japan Hiroshima Red Cross Hosp Dept Internal Med Liver Hiroshima Japan Hiroshima Red Cross Hosp Dept Radiol Hiroshima Japan Kyushu Univ Grad Sch Med Sci Dept Anat Pathol Fukuoka 812 Japan
Hepatocellular carcinoma (HCC) a parts per thousand currency sign2 cm in diameter is considered to have a low potential for malignancy. A retrospective review was undertaken of 149 patients with primary solitary HCC a... 详细信息
来源: 评论
Enhanced Detection of Early Hepatocellular Carcinoma by Serum SELDI-TOF Proteomic Signature Combined with Alpha-Fetoprotein Marker
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ANNALS OF SURGICAL ONCOLOGY 2010年 第9期17卷 2518-2525页
作者: Chen, Lei Ho, David W. Y. Lee, Nikki P. Y. Sun, Stella Lam, Brian Wong, Kwong-Fai Yi, Xin Lau, George K. Ng, Eddy W. Y. Poon, Terence C. W. Lai, Paul B. S. Cai, Zongwei Peng, Jirun Leng, Xisheng Poon, Ronnie T. P. Luk, John M. Univ Hong Kong Queen Mary Hosp Dept Surg Hong Kong Hong Kong Peoples R China Univ Hong Kong Queen Mary Hosp Dept Med Hong Kong Hong Kong Peoples R China Peking Univ Peoples Hosp Dept Hepatobiliary Surg Beijing 100871 Peoples R China Univ Cambridge Metab Res Labs Inst Metab Sci Addenbrookes Hosp NHS Turst Cambridge England Chinese Univ Hong Kong Dept Med & Therapeut Hong Kong Hong Kong Peoples R China Hong Kong Baptist Univ Dept Chem Hong Kong Hong Kong Peoples R China Natl Univ Singapore Dept Pharmacol Singapore 117548 Singapore Natl Univ Singapore Dept Surg Singapore 117548 Singapore
Background. Biomarkers for accurate diagnosis of early hepatocellular carcinoma (HCC) are limited in number and clinical validation. We applied SELDI-TOF-MS Protein-Chip technology to identify serum profile for distin... 详细信息
来源: 评论
Evolution of prognostic factors in hepatocellular carcinoma in Japan
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ALIMENTARY PHARMACOLOGY & THERAPEUTICS 2010年 第3期31卷 407-414页
作者: Nouso, K. Kobayashi, Y. Nakamura, S. Kobayashi, S. Toshimori, J. Kuwaki, K. Hagihara, H. Onishi, H. Miyake, Y. Ikeda, F. Shiraha, H. Takaki, A. Iwasaki, Y. Kobashi, H. Yamamoto, K. Okayama Univ Dept Mol Hepatol Grad Sch Med Dent & Pharmaceut Sci Okayama 7008558 Japan Okayama Univ Dept Gastroenterol & Hepatol Grad Sch Med Dent & Pharmaceut Sci Okayama 7008558 Japan
P>Background The surveillance of hepatocellular carcinoma (HCC) has become prevalent, and the modalities for its treatment have improved. Aim To understand the changes that occur in the characteristics and prognost... 详细信息
来源: 评论
Clinicopathological Significance of ZEB1 Protein in Patients with Hepatocellular Carcinoma
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ANNALS OF SURGICAL ONCOLOGY 2012年 第5期19卷 1700-1706页
作者: Zhou, Yan-Ming Cao, Lu Li, Bin Zhang, Rui-Xiu Sui, Cheng-Jun Yin, Zheng-Feng Yang, Jia-Mei Xiamen Univ Affiliated Hosp 1 Dept Hepatobiliary Pancreato Vasc Surg Xiamen Peoples R China Second Mil Med Univ Eastern Hepatobiliary Surg Hosp Dept Special Treatment Shanghai Peoples R China Second Mil Med Univ Eastern Hepatobiliary Surg Hosp Dept Mol Oncol Shanghai Peoples R China
ZEB1, a member of the ZFH family of proteins (zinc-finger E-box binding homeobox), plays a central role in epithelial-mesenchymal transition (EMT) during carcinogenesis. In this study, we investigated the expression o... 详细信息
来源: 评论