AIM：To investigate the hemostasis effect of hemostasis sponge of collagen and chitosan compound invitro and in ***:The hemostasis sponge of collagen and chitosan compound was made by mixing collegen I extracted by en...
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AIM：To investigate the hemostasis effect of hemostasis sponge of collagen and chitosan compound invitro and in ***:The hemostasis sponge of collagen and chitosan compound was made by mixing collegen I extracted by enzymelytic methods and crosslinked by glutaric dialdeiyde and then *** New zealand rabbit were created with a 1cm×1cm wound in the center artery of the *** center artery of the ear were transected and record the hemostasis time since pressured with hemostasis sponge of collagen and chitosan compound and obsevve its *** other experiements,1cm×1cm bleeding wound were established in the liver of the *** pressured with hemostasis sponge of collagen and chitosan compound on the wounds and record the hemostasis time;The four corner of the hemostasis sponge of collagen and chitosan compound were sutured to investigate the absorption situation with the control of gelatin treated with same ***:The bleeding time using hemostasis sponge of collagen and chitosan compound was 120 seconds compared with 600 seconds of using gelatin,and the hemostasis time using hemostasis sponge of collagen and chitosan compound was 40 weconds compared with 75 seconds of using *** the hemostasis sponge of collagen and chitosan compound and gelatin can be degradated within 5 ***:Hemostasis effect of hemostasis sponge of collagen and chitosan compound is better than that of gelatin and it has an promising future in surgery.
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