To describe an open surgical technique for transplanting fresh ovarion tissue to the anterior abdominal wall at the incision site and to determine whether ovarian function would be restored after transplantation. Case...
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To describe an open surgical technique for transplanting fresh ovarion tissue to the anterior abdominal wall at the incision site and to determine whether ovarian function would be restored after transplantation. Case study. Academic medical center. A 44- year- old patient who underwent an operation for uterine fibroids. Microsurgical reconstruction of ovarian cortex and its transplantation to the anterior abdominal wall at incision site of Pfannenstiel. Follicular development evident by ultrasound examination; restoration of serum FSH and LH levels to nonmenopausal range; and disappearance of menopausal symptoms. Early postoperative FSH, LH, and E2 levels showed that menopause was confirmed. Postoperative hormone levels at months 2, 3, and 6 were as follows: FSH: 77.86, 79.50, and 13.70 mIU/mL; LH: 34.60, 33.92, and 8.78 mIU/mL; E2: 29, 46, and 48 pg/mL. The patient is still followed up for postmenopausal status. Autotransplantation of cortical strips to the anterior abdominal wall at the incision site without further inci sion can be a logical solution for the patients at early climacteric age.
Objective: To discuss the 18-month follow-up results of fresh ovarian cortical tissue transplant. Design: Case study. Setting: Academic medical center. Patient(s): A 46-year-old patient who was operated on for uterine...
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Objective: To discuss the 18-month follow-up results of fresh ovarian cortical tissue transplant. Design: Case study. Setting: Academic medical center. Patient(s): A 46-year-old patient who was operated on for uterine fibroids, and who then received an ovarian tissue transplant in July 2003. Intervention(s): Serum hormone levels were measured at 3-month intervals. Main Outcome Measure(s): Follicular development evident by ultrasound examination; serum hormone levels (FSH, LH, E2). Result(s): Preoperative and 3rd-, 6th-, 9th-, 12th-, 15th-, and 18th-month hormone levels were, respectively, as follows: FSH: 9.06, 79.5, 13.7, 16.66, 51.91, 44.37, and 24.17 mIU/mL; LH: 5.91, 33.92, 8.78, 21.83, 38.31, 40.85, and 22.4 mIU/mL; E2: 166, 46, 48, 117, 31, 14.4, and 137.7 pg/mL. Folliculogenesis was confirmed by ultrasonography at the 6th, 9th, and 18th months during the follow-up period. Conclusion(s): Fresh ovarian autotransplantation may be a logical alternative for hormonal support for a specific patient group.
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