2型糖尿病(Type 2 Diabetes Mellitus, T2DM)常伴有多器官脂肪沉积异常,准确评估这些脂肪沉积对于疾病的早期诊断、病情监测和治疗方案制定具有重要意义。磁共振Dixon技术作为一种先进的成像技术,能够实现水脂分离,为多器官脂肪定量提供了新的手段。本文综述了磁共振Dixon技术的基本原理、优势以及在T2DM患者肝脏、胰腺、肾脏和骨骼肌等多器官脂肪定量中的应用现状和研究进展,旨在讨论MR定量成像技术在T2DM评估中的优势及面临的一些挑战,为MR量化T2DM病理生理改变提供新的研究思路。Type 2 Diabetes Mellitus (T2DM) is often associated with abnormal fat deposition in multiple organs. Accurate assessment of these fat depositions is of great significance for early diagnosis, disease monitoring, and treatment planning. As an advanced imaging technique, MRI Dixon technique can separate water and fat, providing a new means for quantitative fat assessment in multiple organs. This review summarizes the basic principles and advantages of the MRI Dixon technique, as well as its current applications and research progress in the quantitative fat assessment of the liver, pancreas, kidneys, and skeletal muscles in T2DM patients. It aims to discuss the advantages of MR quantitative imaging techniques in T2DM assessment and some challenges faced, and to provide new research ideas for MR quantification of pathological and physiological changes in T2DM.
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