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陕西中医 2007年第2期28卷 132-134页

作者：湛守青青海省心血管病专科医院 810012

目的:观察中西医结合治疗心脏术后缓慢性心律失常的疗效。方法:用心宝丸(洋金花、人参、鹿茸、肉桂、附子、三七等),同时用西医的方法,已置临时起搏导线者用临时起搏器起博,否则用阿托品或654-2、异丙肾上腺素等药治疗。结果:共治疗286... 详细信息

目的:观察中西医结合治疗心脏术后缓慢性心律失常的疗效。方法:用心宝丸(洋金花、人参、鹿茸、肉桂、附子、三七等),同时用西医的方法,已置临时起搏导线者用临时起搏器起博,否则用阿托品或654-2、异丙肾上腺素等药治疗。结果:共治疗286例,总有效率98%。提示:中西医结合治疗心脏术后缓慢性心律失常,疗效显著,临床上值的应用。

关键词：心脏外科手术/并发症心律失常/中西医结合疗法 @心宝丸异丙肾上腺素/治疗应用

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Long QT syndrome: Diagnosis and management

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AMERICAN HEART JOURNAL 2002年第1期143卷 7-14页

作者： Khan, IA Creighton Univ Cardiac Ctr Omaha NE 68131 USA Creighton Univ Div Cardiol Dept Med Omaha NE 68131 USA Creighton Univ Sch Med Omaha NE USA

Background Long QT syndrome (LQT) is characterized by prolongation of the QT interval, causing torsade de pointes and sudden cardiac death. The LQT is a disorder of cardiac repolarization caused by alterations in the transmembrone potassium and sodium currents. Congenital LQT is a disease of transmembrane ion-channel proteins. Six genetic loci of the disease have been identified. Sporadic cases of the disease occur as a result of spontaneous mutations. The acquired causes of LQT include drugs, electrolyte imbalance, marked bradycardia, cocaine, organophosphorus compounds, subarachnoid hemorrhage, myocardial ischemia, protein sparing fasting, autonomic neuropathy, and human immunodeficiency virus disease. Methods Data on the diagnosis and management of LQT were thoroughly reviewed. Results and Conclusions The diagnosis of LQT primarily rests on clinical and electrocardiographic features and family history. The clinical presentations range from dizziness to syncope and sudden death. Genetic screening is available primarily as a research tool. Short-term treatment of LQT is aimed at preventing the recurrences of torsades and includes intravenous magnesium and potassium administration, temporary cardiac pacing, withdrawal of the offending agent, correction of electrolyte imbalance, and, rarely, intravenous isoproterenol administration. The long-term treatment is aimed at reducing the QT-interval duration and preventing the torsades and sudden death and includes use of oral P-adrenergic blockers, implantation of permanent pacemaker/cardioverter-defibrillator, and left thoracic sympathectomy. Sodium channel blockers are promising agents under investigation. Electrocardiograms are recorded for screening of family members. The data favor treating asymptomatic patients, if <40 years old at the time of diagnosis, with beta-adrenergic blockers.

关键词：肾上腺素能β受体拮抗剂/治疗应用年龄因素心脏起搏人工强心药/投药和剂量猝死心脏/病因学电抗休克心电描记术家庭遗传筛查异丙肾上腺素/治疗应用 QT延长综合征/诊断 QT延长综合征/病因学 QT延长综合征/治疗镁/治疗应用突变钾/治疗应用钾通道/遗传学钠通道/遗传学扭转性室速/病因学扭转性室速/治疗青少年成年人老年人儿童女(雌)性人类男(雄)性中年人

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ISOPROTERENOL IN OFFSETTING ADVERSE EFFECTS OF VASOPRESSIN IN CIRRHOTIC PATIENTS

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AMERICAN JOURNAL OF SURGERY 1975年第2期129卷 130-136页

作者： SIRINEK, KR THOMFORD, NR OHIO STATE UNIV COLL MEDDEPT SURGCOLUMBUSOH 43210

Vasopressin administered as a peripheral infusion (40 U/hr) significantly reduced portal vein pressure in ten awake patients with cirrhosis and portal hypertension. A vasopressin-induced reduction in cardiac output occurred in five of the ten patients (50 per cent). Vasopressin-induced changes in systemic arterial pressure, heart rate, and portal venous pressure were independent of alterations in cardiac output. When the five patients with vasopressin-induced reductions in cardiac output were given a combination of vasopressin and isoproterenol, cardiac output was maintained and the reduction in portal vein pressure was equal to that observed with unopposed vasopressin therapy. Thus, the addition of isoproterenol prevented a vasopressin-induced reduction in cardiac output while permitting vasopressin to reduce portal vein pressure.

关键词：血压/药物作用心排血量/药物作用药物评价食管和胃静脉曲张/药物疗法胃肠出血/药物疗法心率/药物作用输注胃肠外异丙肾上腺素/治疗应用肝硬化/并发症肝硬化/病理生理学门脉系统/药物作用血管升压素类/投药和剂量血管升压素类/治疗应用女(雌)性人类男(雄)性

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STOKES-ADAMS ATTACKS DUE TO ACUTE NONSPECIFIC MYOCARDITIS

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AMERICAN HEART JOURNAL 1975年第2期90卷 172-178页

作者： LIM, CH TOH, CCS CHIA, BL LOW, LP UNIV SINGAPORE DEPT MEDMED UNIT 2SEPOY LINESSINGAPORE 3SINGAPORE

Ten patients, all below 30 years of age (8 females and 2 males) developed Stokes-Adams attacks from complete heart block due to acute nonspecific myocarditis. Coexisting thyrotoxicosis was present in two patients and cardiogenic shock was seen in four. Temporary transvenous pacing was instituted in all but one patient. Except for two patients who developed permanent complete heart block, normal A-V conduction returned in between 1 to 12 hours after ventricular pacing in seven patients and after 12 hours of isoprenaline therapy in the final patient. The ECG returned to normal in six patients and all 10 patients survived their acute illness.

关键词：急性病阿-斯综合征/诊断阿-斯综合征/病因学阿-斯综合征/治疗年龄因素电抗休克心电描记术异丙肾上腺素/治疗应用心肌炎/并发症休克心原性/病因学青少年成年人儿童女(雌)性人类男(雄)性

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UNRESPONSIVENESS TO ISOPROTERENOL

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CHEST 1976年第6期70卷 691-693页

作者： JENNE, JW CHICK, TW VET ADM HOSP ALBUQUERQUE NM 87108 USA UNIV NEW MEXICO SCH MED DIV PULMONARY DIS ALBUQUERQUE NM 87106 USA UNIV NEW MEXICO SCH MED ALBUQUERQUE NM 87106 USA

A previous report presented the finding of apparent patient unresponsiveness to isoproterenol in patients whose airways respond to both isoetharine and terbutaline. Possible reasons for this effect are discussed: airway compliance variability;possibility that propellant aerosol per se can induce bronchoconstriction;inconsistent response to bronchodilator drug;and the question of whether nonresponsiveness of bronchial .beta.-2 adrenergic receptors can occur with one agonist but not with another.

关键词：气雾剂气道阻力/药物作用哮喘/药物疗法支气管/药物作用支气管痉挛/化学诱导异丙肾上腺素/投药和剂量异丙肾上腺素/治疗应用受体肾上腺素能/药物作用人类

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Use of clonidine for chemical submission

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JOURNAL OF TOXICOLOGY-CLINICAL TOXICOLOGY 2000年第3期38卷 329-332页

作者： Lusthof, KJ Lameijer, W Zweipfenning, PGM Forens Sci Inst Dept Toxicol NL-2288 GD Rijswijk Netherlands Onze Lieve Vrouwe Gasthuis Amsterdam Netherlands

Case Report: An East-European prostitute in Amsterdam robbed several victims' after having sedated them with clonidine solution (available as plastic ampoules of eyedrops) added to her victims' drinks. One victim was hospitalized. His symptoms included bradycardia, hypotension, hypothermia, pallor, cyanosis, and impaired consciousness, Treatment included isoprenaline for 28 hours. The victim was released from hospital the next day, In court, the female offender confessed and was sentenced to prison for 31/2 years. She may have administered doses as high as 8 mg clonidine.

关键词：抗高血压药/中毒可乐定/中毒犯罪受害者异丙肾上腺素/治疗应用荷兰中毒/药物疗法女(雌)性人类男(雄)性

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Priorities governing the care of the critically ill

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Hospital Practice 1976年第9期11卷 67-76页

作者： Weil, M.H. Carlson, R.W. United States

Despite the remarkable amalgam of highly sophisticated and very simple techniques that constitute modern critical care medicine, central to its emergence has been the realization that all patients brought to the critical care unit, whether their problem is essentially pulmonary, cardiovascular, infectious, or other, face essentially the same problem: that of immediate survival. They must therefore be approached with a certain set of priorities in a systematic fashion, seeing to the more immediate threats to life first. Trial and error constitutes hit or miss manipulation and has no place in the critical care unit when immediate survival is at stake.

关键词：血气分析血压加利福尼亚计算机危重病人医疗多巴胺/治疗应用输注胃肠外重症监护病房异丙肾上腺素/治疗应用乳酸盐类/血液监测生理学容积渗克分子浓度渗透压病人医疗护理计划血浆预后呼吸功能不全/治疗休克/治疗尿人类

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异丙肾气雾剂吸入对正常人、哮喘和慢性支气管炎患者气道阻塞可逆性的探讨

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中华内科杂志 1985年第3期24卷 129-132+188页

作者：黄征波罗慰慈马毅潘兰英中国医学科学院首都医院内科

本文对55例正常成人、130例支气管哮喘和60例慢性支气管炎患者进行了异丙肾气雾剂吸入试验。提出该试验的正常反应参考值,比较了几项通气功能检查在该试验中的敏感性,并对气道阻塞可逆性标准作了初步的探讨。

关键词：哮喘/药物疗法异丙肾上腺素/治疗应用支气管炎/药物疗法

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