检索结果-内蒙古大学图书馆

Early measles virus infection is associated with the development of inflammatory bowel disease

AMERICAN JOURNAL OF GASTROENTEROLOGY 2000年第6期95卷 1480-1485页

作者： Pardi, DS Tremaine, WJ Sandborn, WJ Loftus, EV Poland, GA Harmsen, WS Zinsmeister, AR Melton, LJ Mayo Clin & Mayo Fdn Dept Hlth Sci Res Clin Epidemiol Sect Rochester MN 55905 USA Mayo Clin & Mayo Fdn Mayo Vaccine Res Grp Div Gastroenterol & Hepatol Rochester MN 55905 USA Mayo Clin & Mayo Fdn Biostat Sect Clin Pharmacol Unit Rochester MN 55905 USA

OBJECTIVE: The measles virus has been implicated as a possible etiological agent in the development of inflammatory bowel disease (IBD). Measles infection at an early age is associated with subacute sclerosing panencephalitis, a degenerative neurological condition caused by persistent measles infection of the central nervous system. We sought to determine whether infection with measles virus at an early age was also associated with an increased risk of developing IBD. METHODS: Patients with measles infection diagnosed before the age of 5 yr were identified through the diagnostic indices of the Mayo Clinic and the Rochester Epidemiology Project. A questionnaire was used to ascertain a subsequent history of IBD, which was confirmed by records from the subjects' physicians. The risks of developing Crohn's disease and ulcerative colitis were calculated relative to expected rates for these conditions in the Olmsted County, Minnesota population. RESULTS: Of 1164 eligible cases, 662 (57%) completed the questionnaire. There were six confirmed cases of Crohn's disease and six of ulcerative colitis. The expected number of cases was 1.9 for Crohn's disease (standardized incidence ratio [SIR] 3.1, 95% confidence interval [CI] 1.1-6.8) and 2.0 for ulcerative colitis (SIR 3.0, CT 1.1-6.5). There was a trend towards a higher risk of developing IBD with an earlier age of infection. CONCLUSIONS: Early measles infection is associated with an increased risk of developing Crohn's disease and ulcerative colitis. The risk may be higher with earlier infection. (Am J Gastroenterol 2000.95:1480-1385. (C) 2000 by Am. Coll. of Gastroenterology).

关键词：衰老/生理学结肠炎溃疡性/流行病学结肠炎溃疡性/病毒学 Crohn病/流行病学 Crohn病/病毒学发病率炎性肠疾病/病毒学麻疹问卷调查危险因素儿童学龄前人类

来源：评论

学校读者我要写书评

暂无评论

Epidemiology of ulcerative colitis in Israel: A survey of Israeli kibbutz settlements

引用

AMERICAN JOURNAL OF GASTROENTEROLOGY 2000年第3期95卷 693-698页

作者： Niv, Y Abuksis, G Fraser, GM Tel Aviv Univ Rabin Med Ctr Dept Gastroenterol IL-49100 Petah Tiqwa Israel Tel Aviv Univ Sackler Fac Med IL-49100 Petah Tiqwa Israel

OBJECTIVE: The incidence of ulcerative colitis ranges from 3 to 15 cases per 100,000 persons per year with a prevalence of 50-80 cases per 100,000, and the disease is 3-5 times more common among Jews. In Israel, Ashkenazi Jews have a higher incidence than Sephardi Jews, but a lower incidence than Ashkenazi Jews in the United States or Northern Europe. The aim of this study was to examine the prevalence, mean annual incidence, and clinical patterns of ulcerative colitis in a stable population of communal settlements (kibbutz). METHODS: We repeated a community-based survey in 124,400 kibbutz residents, 10 yr after our first study. This population represents 2.5% of the Jewish population of Israel. All ulcerative colitis patients were located by contacting the kibbutz clinics of the 269 kibbutz settlements (100% compliance). Data were updated to December 31st, 1997, which was designated the point prevalence date, and included information on gender, age, origin, education, profession, extent of the inflammatory process, clinical spectrum of the disease, therapy, complications of the disease, and treatment. The mean annual incidence for the 10 yr was calculated from the prevalence data. Only cases with a definite diagnosis of ulcerative colitis made in a recognized gastroenterology unit were accepted into the study. RESULTS: There were 208 confirmed cases of ulcerative colitis disease, 113 women and 95 men (female:male ratio = 1.19). The prevalence rate rose from 121.0/100,000 in 1987 to 167.2/100,000 in 1997 (p < 0.001). The prevalence rates were higher in women than men. Prevalence was highest in Israeli-born members in 1987 but in European/American-born members in 1997. The average annual incidence rate for the 10-yr period was 5.04/100,000/yr. In 1987, 146 cases of ulcerative colitis were collected. During 10 yr of surveillance 17 patients left the kibbutz, 12 died, and 62 new cases were added. The mean age at presentation of the disease was lower in 1987 than in 199

关键词：结肠炎溃疡性/诊断结肠炎溃疡性/流行病学结肠炎溃疡性/病因学文化交叉比较横断面研究健康调查发病率以色列/流行病学青少年成年人老年人儿童儿童学龄前女(雌)性人类男(雄)性中年人

来源：评论

学校读者我要写书评

暂无评论

Concurrence of inflammatory bowel disease and multiple sclerosis

引用

MAYO CLINIC PROCEEDINGS 2000年第8期75卷 802-806页

作者： Kimura, K Hunter, SF Thollander, MS Loftus, EV Melton, LJ O'Brien, PC Rodriguez, M Phillips, SF Mayo Clin & Mayo Fdn Gastroenterol Res Unit Dept Internal Med Rochester MN 55905 USA Mayo Clin & Mayo Fdn Dept Neurol Rochester MN 55905 USA Mayo Clin & Mayo Fdn Duv Gastroenterol & Hepatol & Internal Med Rochester MN 55905 USA Mayo Clin & Mayo Fdn Dept Hlth Sci Res Rochester MN 55905 USA

Objectives: To quantify the coexistence of inflammatory bowel disease (IBD) and multiple sclerosis (MS) and to characterize the diseases when they coexist, Patients and Methods: In this retrospective study of medical records spanning 1950 through 1995, the diagnoses of Crohn disease (CD), ulcerative colitis (UC), and MS were based on review of inpatient and outpatient records by a gastroenterologist and a neurologist, Results: We identified 4 residents of Olmsted County, Minnesota, with IBD (3 UC, I CD) who had concurrent, clinically definite MS;all had mild neurologic disease with little disability. These comprised 1% of the IBD and 1.8% of the MS cohort, The CD patient had undergone terminal ileal resection;of the UC patients, 2 had pancolitis, and I had proctosigmoiditis. The observed prevalence of MS at onset of IBD was 3.7 times the expected (95% confidence interval, 0.8-10.8), We also reviewed the records of 32 referral patients with both diagnoses. Disability from MS was moderate at median follow-up of 8.5 Sears. By 15 years, ambulation was impaired in most patients. Neurologic disability was similar between patients with CD and UC, Conclusions: Concurrence of the 2 diseases was greater than expected. Although MS and IBD may share common predisposing factors, not enough information is available to speculate about possible mechanisms.

关键词：结肠炎溃疡性/流行病学 Crohn病/流行病学发病率炎性肠疾病/流行病学病案明尼苏达/流行病学多发性硬化/流行病学患病率回顾性研究青少年成年人老年人女(雌)性人类男(雄)性中年人

来源：评论

学校读者我要写书评

暂无评论

Lack of association between smoking and Crohn's disease but the usual association with ulcerative colitis in Jewish patients in Israel: A multicenter study

引用

AMERICAN JOURNAL OF GASTROENTEROLOGY 2000年第2期95卷 474-478页

作者： Reif, S Lavy, A Keter, D Fich, A Eliakim, R Halak, A Broide, E Niv, Y Ron, Y Patz, J Odes, S Villa, Y Gilat, T Tel Aviv Sourasky Med Ctr Dept Gastroenterol IL-64239 Tel Aviv Israel Rambam Med Ctr Haifa Israel Kaplan Hosp Rehovot Israel Soroka Hosp Beer Sheva Israel Hadasah Mt Scopus Hosp Jerusalem Israel Asaf Harofe Hosp Zerifin Israel Belinson Hosp Petah Tiqwa Israel Wolfson Govt Hosp Holon Israel Shaarei Zedek Hosp Jerusalem Israel Tel Aviv Univ IL-69978 Tel Aviv Israel

OBJECTIVE: The association between smoking and inflammatory bowel disease (IBD) is well established, but data in Jewish patients in Israel were discrepant. The aim of this study was to examine the smoking habits of Jewish IBD patients in Israel in a large scale, multicenter study. METHODS: Patients with established IBD aged 18-70 yr were interviewed in relation to smoking and other habits. Two controls (one clinic and one neighborhood control matched by age, sex, community group, and education) were sought for each subject. RESULTS: A total of 534 patients (273 ulcerative colitis [UC], and 261 Crohn's disease [CD]), along with 478 clinic controls and 430 neighborhood controls, were interviewed. There was no significant difference in the smoking habits between CD patients and their controls. Of patients with CD, 24.5% Were current smokers, as compared to 19.9% Of clinic controls and 25.2% of neighborhood controls (NS). The odds ratio for CD in current smokers was 1.30 (95% confidence interval 0.85-1.99) versus clinic controls, and 0.96 (0.63-1.46) versus neighborhood controls. There were also no significant differences in the proportion of ex-smokers between the groups. Only 12.9% of UC patients were current smokers versus 21.9. % Clinic controls, and 26.4% community controls (p < 0.005). The proportions of ex-smokers were higher in UC patients 29.7% versus 25.9%, and 19.5% in their respective controls (p < 0.001 vs community controls). No significant differences were found in the proportions of never-smokers between IBD patients and controls. All the above trends were similar in four different parts of the country. The proportion of current smokers in UC decreased with the extent of disease (19.7% in proctitis, 13.6% in left-sided, and 4.5% in total colitis) (p < 0.05). Patients with UC were more likely to be light smokers(1-10 cigarettes/day), whereas patients with CD were more likely to be moderate smokers (11-20 cigarettes/day) in comparison to their controls. CO

关键词：病例对照研究结肠炎溃疡性/流行病学置信区间 Crohn病/流行病学教育程度以色列/流行病学犹太人/分类犹太人/统计学和数值数据比值比吸烟/流行病学戒烟/统计学和数值数据青少年成年人老年人女(雌)性人类男(雄)性中年人

来源：评论

学校读者我要写书评

暂无评论

The effects of migration on ulcerative colitis: A three-year prospective study among Europeans and first- and second-generation South Asians in Leicester (1991-1994)

引用

AMERICAN JOURNAL OF GASTROENTEROLOGY 1999年第10期94卷 2918-2922页

作者： Carr, I Mayberry, JF Leicester Gen Hosp NHS Trust Gastrointestinal Dis Unit Leicester LE5 4PW Leics England

OBJECTIVE: Our aim was to measure prospectively the incidence of ulcerative colitis in Leicester City and to compare this with a previous retrospective study in the same area. We also sought to compare the incidence and disease extent in the European community with that of the South Asian community and to compare the disease extent between first-and second-generation South Asian migrants. METHODS: A 3-yr prospective study of ulcerative colitis in the city of Leicester took place from October 1, 1991 to September 30, 1994 and included all cases resident in Leicester City and diagnosed as having ulcerative colitis, regardless of the extent and severity of the disease. RESULTS: Extensive colitis was commoner in second-generation migrants than in the first generation (x(2) = 4.3, p = 0.04) and was comparable to the European community. The annual average incidence of ulcerative colitis was 9.1/10(5) population/yr (95% confidence interval [CI] 7.1-11.3), which is similar to the previous retrospective study. However, the annual average incidence of ulcerative colitis in the European population was 7.0/10(5) population/yr (95% CI 5-9.5), whereas that of the South Asian population was 17.2/10(5) population/yr (95% CI 11.8- 24.3), confirming that the risk of ulcerative colitis in this particular community is exceptionally high. CONCLUSIONS: These early results suggest that the disease pattern follows that of the indigenous population after only one generation and requires monitoring over the next decade. The incidence of ulcerative colitis in the South Asian population is high and continuing to rise. (C) 1999 by Am. Coll. of Gastroenterology.

关键词：亚洲西部/人种学结肠炎溃疡性/流行病学结肠炎溃疡性/人种学移民(移出和移入) 英格兰/流行病学发病率前瞻性研究危险因素成年人人类

来源：评论

学校读者我要写书评

暂无评论

DISEASES OF COLON AND RECTUM IN BOLIVIA

引用

AMERICAN JOURNAL OF SURGERY 1975年第6期129卷 661-664页

作者： RIOSDALENZ, J SMITH, LB THOMPSON, TF HOSP METODISTA DIV SURGCASILLA 4826LA PAZBOLIVIA HOSP METODISTA DIV PATHOLLA PAZBOLIVIA HOSP OBRERO LA PAZBOLIVIA

A review of the surgical and autopsy records from two general hospitals in La Paz, Bolivia, discloses an incidence of colon and rectal disease, excluding hemorrhoids, of 0.6 per cent (138 of 22,361 surgical cases) and 2.5 per cent (16 of 640 consecutive autopsies). Acquired megacolon complicated by volvulus represented more than half of all cases in the surgical series. Ulcerative colitis, diverticular disease, and neoplastic polyps represented less than 10 per cent of the cases of colonic diseasce. Only ten cases of carcinoma of the colon were seen, whereas five cases of granulomatous colitis or ileocolitis were detected in the same surgical material. Among sixty-four lesions of the rectum, so-called retention polyps accounted for 54.5 per cent of the cases, with carcinoma next in frequency (25 percent), and the remainder being different varieties of inflammatory conditions. In the autopsy material almost half of the cases were infectious conditions, followed by congenital malformations and complicated acquired megacolon. No case of diverticular disease of the colon or neoplastic polyps was seen, and there was only one case of cancer of the large bowel. Because of the high incidence of acquired megacolon and the low incidence of cancer, ulcerative colitis, adenomatous polyps, and diverticular disease of the colon, possible etiopathogenic factors of these conditions are discussed in comparison with their incidence in other developed and developing countries of the world.

关键词：高海拔玻利维亚结肠炎溃疡性/流行病学结肠疾病/流行病学结肠疾病/病因学 Crohn病/流行病学发展中国家膳食憩室结肠/流行病学印第安人南美洲肠肿瘤/流行病学肠梗阻/流行病学肠息肉/流行病学巨结肠/流行病学直肠疾病/流行病学直肠疾病/病因学性别因素女(雌)性人类男(雄)性

来源：评论

学校读者我要写书评

暂无评论

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案：

请选择收藏分类：

通借通还

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：