检索结果-内蒙古大学图书馆

A double-blind comparison of cephalexin and ampicillin in the treatment of bronchitis

Journal of Antimicrobial Chemotherapy 1975年第Sup3期1卷 99-103页

作者： Cooke, Deborah M. Garrett, R.T. Medical Department Glaxo Laboratories Ltd Greenford United Kingdom

In a double-blind multi-centre trial conducted in general practice, cephalexin and ampicilhin were compared in the treatment of acute and chronic bronchitis. The dose for both antibiotics was 500 mg 4 times daily for 10 days. One hundred and eleven patients were assessed clinically by their physician at fixed intervals during treatment. Patients also subjectively assessed their improvement at each visit. Clinical and subjective assessments indicated that the two treatments were equally effective, with a similar swift and satisfactory response (recovery or marked improvement) in 91% of patients taking cephalexin and 96% taking ampicillin. Side effects were mild, and comparable in number and type with each therapy. © 1975 Oxford University Press.

关键词：氨苄西林/副作用氨苄西林/治疗应用支气管炎/药物疗法支气管炎/微生物学头孢氨苄/副作用头孢氨苄/治疗应用临床试验(主题) 用药计划表痰/微生物学时间因素青少年成年人老年人女(雌)性人类男(雄)性中年人

来源：评论

学校读者我要写书评

暂无评论

Respiratory virus infections after marrow transplant: The Fred Hutchinson Cancer Research Center experience

引用

American Journal of Medicine 1997年第3A期102.0卷 27-30页

作者： Bowden, Raleigh A. Department of Infectious Diseases Fred Hutchinson Cancer Research Center Seattle WA United States

Respiratory virus infections are becoming increasingly appreciated causes of morbidity and mortality in bone marrow transplant recipients. Fred Hutchinson Cancer Research Center (FHCRC) has had considerable experience with respiratory syncytial virus (RSV), parainfluenza, influenza, and rhinovirus infections in these patients over the past decade. Overall, RSV accounted for the majority of community-acquired respiratory virus infections (35%), followed by parainfluenza virus (30%), rhinovirus (25%), and influenza virus (11%). Pneumonia occurred frequently among those infected with RSV (49%) or parainfluenza (22%) but infrequently among those infected with influenza virus (<10%) or rhinovirus (3%). In one study conducted at FHCRC, intravenous ribavirin was not effective against established RSV pneumonia. In another, ongoing study, however, short-course aerosolized ribavirin appears to reduce progression of upper respiratory tract infection to pneumonia, but further study is needed. Neither strategy had an obvious impact on viral shedding, although persistence of viral shedding did not correlate with either the development or the outcome of pneumonia. © 1997 by Excerpta Medica, Inc.

关键词：抗病毒药/投药和剂量抗病毒药/治疗应用骨髓移植/免疫学社区获得性感染/药物疗法社区获得性感染/病毒学用药计划表输注静脉内正黏病毒科/分离和提纯试点项目肺炎病毒性/病毒学呼吸道合胞病毒/分离和提纯呼吸道感染/药物疗法呼吸道感染/流行病学呼吸道感染/病因学呼吸道感染/病毒学鼻病毒属/分离和提纯利巴韦林/投药和剂量利巴韦林/治疗应用治疗结果病毒性疾病/药物疗法病毒性疾病/流行病学病毒性疾病/病因学病毒性疾病/病毒学华盛顿人类

来源：评论

学校读者我要写书评

暂无评论

Duration and intensity of anticoagulation among patients with genetic predispositions to venous thrombosis

引用

Current Cardiology Reports 1999年第2期1卷 88-90页

作者： Ridker, Paul M. Divisions of Cardiovascular Diseases and Preventive Medicine Brigham and Women's Hospital Harvard Medical School Boston MA 02115 75 Francis Street United States

来源：评论

学校读者我要写书评

暂无评论

Medication challenges in the assisted living facility.

引用

Journal of the American Pharmaceutical Association (Washington,D.C. : 1996) 1999年第2期39卷 222-225;quiz293-294页

作者： Crutchfield, D.B. Pharmacy Consulting Care Knoxville Tenn. 37922 USA.

OBJECTIVE: To review current challenges to the provision of safe and effective pharmaceutical care in assisted living facilities. DATA SOURCES: Current literature. DATA SYNTHESIS: The assisted living industry has experienced tremendous growth and offers pharmacists lucrative business opportunities. However, pharmacists must understand the varied nature of both the facilities and the residents. Assisted living residents are entitled to independence and privacy, a fact that presents many challenges in terms of monitoring the safe and accurate administration of medications. CONCLUSION: Assisted living facilities provide elderly residents a new and unique blend of independent living and daily support. To provide effective pharmacy services to these facilities, pharmacists must consider their specific needs in terms of medication use processes, packaging, delivery, documentation, and storage.

关键词：用药计划表药物包装药物贮藏老人疗养院卫生服务使用研究/方法药学服务老年人人类

来源：评论

学校读者我要写书评

暂无评论

氟康唑胶囊150mg单剂治疗阴道念珠菌病

引用

新药与临床 1995年第5期14卷 319-319页

作者：吴绍熙郭宁如席丽艳中国医学科学院中国协和医科大学皮肤病研究所

目的：探讨氟康唑胶囊单剂对阴道念珠菌病的疗效。方法：２９例病人（年龄４４±ｓ６ａ）分２组，一组２３例，用氟康唑１５０ｍｇ顿服，另一组６例以氟康唑１５０ｍｇ，ｐｏ，ｑｄ×１０ｄ。总量为１５００ｍｇ．结果：顿服组... 详细信息

目的：探讨氟康唑胶囊单剂对阴道念珠菌病的疗效。方法：２９例病人（年龄４４±ｓ６ａ）分２组，一组２３例，用氟康唑１５０ｍｇ顿服，另一组６例以氟康唑１５０ｍｇ，ｐｏ，ｑｄ×１０ｄ。总量为１５００ｍｇ．结果：顿服组治疗后７ｄ及３０ｄ复查１次，临床治愈率为８３％，真菌清除率亦为８３％。另一组经１０ｄ治疗后均痊愈。结论：１５０ｍｇ氟康唑１次顿服可治愈绝大部分念珠菌性阴道炎病人，且副作用小。

关键词：氟康唑外阴阴道念珠菌病用药计划表

来源：评论

学校读者我要写书评

暂无评论

吡喹酮治疗儿童卫氏并殖吸虫病(肝型)的合理剂量

引用

中国新药与临床杂志 1998年第4期17卷 240-240页

作者：朱维克浙江残疾儿童康复中心儿科

目的：探索吡喹酮治疗儿童卫氏并殖吸虫病（肝型）的合理剂量。方法：２６例并殖吸虫病儿，按收治先后分２组，小剂量组（１７例）给总量１２０ｍｇ／ｋｇ，分为４剂，ｐｏ，ｂｉｄ×２ｄ。大剂量组（９例）给总量２００ｍｇ／ｋｇ... 详细信息

目的：探索吡喹酮治疗儿童卫氏并殖吸虫病（肝型）的合理剂量。方法：２６例并殖吸虫病儿，按收治先后分２组，小剂量组（１７例）给总量１２０ｍｇ／ｋｇ，分为４剂，ｐｏ，ｂｉｄ×２ｄ。大剂量组（９例）给总量２００ｍｇ／ｋｇ，分为６剂，ｐｏ，ｂｉｄ×３ｄ。服药前２组均作并殖吸虫抗原皮试，肝功能、清蛋白／球蛋白比值、免疫球蛋白、γ球蛋白、血沉、白血球总数和嗜酸粒细胞计数检查，服药后２ｍｏ和１ａ后复查。结果：２ｍｏ后小剂量组白细胞总数和嗜酸粒细胞计数仍显著偏高，大剂量组略低。２组抗原皮试全部阳性外，其他各项均恢复正常。１ａ后２组病儿上述各项正常，唯抗原皮试１例转阴。结论：大剂量组疗效较好，优于小剂量组。

关键词：吡喹酮并殖吸虫病儿童用药计划表剂量

来源：评论

学校读者我要写书评

暂无评论

日服2次与4次胶态次枸橼酸铋剂治疗消化性溃疡的比较

引用

中国新药与临床杂志 1993年第2期 118-118页

作者：贺中式江西省瑞昌市人民医院瑞昌 332200

内窥镜证实消化性溃疡308例,其中154例内服胶态次枸橼酸铋冲剂1包(含铋110mg),bid,另154例则1包,qid,疗程均为45d。结果溃疡治愈率前者82.5％,幽门螺旋杆菌(HP)转阴率79.1％;后者治愈率为85.7％,HP转阴率81.3％,两者疗效差异不显著,前... 详细信息

内窥镜证实消化性溃疡308例,其中154例内服胶态次枸橼酸铋冲剂1包(含铋110mg),bid,另154例则1包,qid,疗程均为45d。结果溃疡治愈率前者82.5％,幽门螺旋杆菌(HP)转阴率79.1％;后者治愈率为85.7％,HP转阴率81.3％,两者疗效差异不显著,前者方法简便,不良反应少,值得推广试用。

关键词：铋/治疗应用消化性溃疡/药物疗法幽门螺旋杆菌用药计划表

来源：评论

学校读者我要写书评

暂无评论

Loratadine/pseudoephedrine for nasal symptoms in seasonal allergic rhinitis: a double-blind, placebo-controlled study

引用

Ear, nose, & throat journal 2000年第4期79卷 E4-E4页

作者： E A McFadden A Gungor B Ng B Mamikoglu R Moinuddin J Corey Allergy Clinic University of Chicago Medical Center IL USA.

In this double-blind, placebo-controlled, crossover, parallel study, we treated 20 adults who had seasonal allergic rhinitis with once-daily fixed-combination loratadine/pseudoephedrine sulfate to observe its effect on relieving symptoms, primarily nasal congestion. Acoustic rhinometry detected a trend toward improvement in nasal patency, although the difference between pre- and post-treatment measures was not statistically significant. Endoscopic inferior turbinate photography documented that treatment led to statistically significant reductions in the amount of nasal edema and nasal secretions. The results of a quality-of-life questionnaire suggested that treatment alleviated nasal and ocular symptoms of rhinoconjunctivitis. An analysis of subjective visual analog scale scores showed a trend toward improvement in most but not all nasal symptoms. We conclude that once-a-day fixed-combination loratadine/pseudoephedrine is effective in relieving nasal congestion in patients with seasonal allergic rhinitis.

关键词：抗变态反应药/投药和剂量抗变态反应药/治疗应用交叉研究双盲法用药计划表复方合剂内窥镜检查麻黄碱/投药和剂量麻黄碱/治疗应用组胺H1拮抗剂/投药和剂量组胺H1拮抗剂/治疗应用氯雷他定/投药和剂量氯雷他定/治疗应用病人满意度摄影术生活质量/心理学鼻炎变应性季节性/药物疗法鼻炎变应性季节性/心理学治疗结果血管收缩药/投药和剂量血管收缩药/治疗应用成年人女(雌)性人类男(雄)性中年人

来源：评论

学校读者我要写书评

暂无评论

Insulin secretion in growth hormone-deficient adults: Effects of 24 months' therapy and five days' acute withdrawal of recombinant human growth hormone

引用

METABOLISM-CLINICAL AND EXPERIMENTAL 1999年第11期48卷 1387-1396页

作者： Kamarudin, N Hew, FL Christopher, M Alford, J Rantzau, C Ward, G Alford, F St Vincents Hosp Dept Endocrinol & Diabet Fitzroy Vic 3065 Australia Univ Melbourne Dept Med Melbourne Vic Australia

beta-Cell function in growth hormone (GH)-deficient (GHD) adults is poorly documented. beta-Cell function was therefore studied in 10 GHD adults (age, 40 +/- 3 years;weight, 79.3 +/- 4.8 kg;body mass index [BMI], 27.5 +/- 1.3 kg . m(-2)) before and after 6- and 24-month recombinant human GH (rhGH) therapy (0.24 IU . kg(-1) . wk(-1)) compared with 10 age-, sex-, weight-, and BMI-matched control subjects. With rhGH therapy, fat-free mass (FFM) increased (48.2 +/- 4.9, 52.5 +/- 4.8, and 59 +/- 6.8 kg, respectively) and fat mass (FM) decreased (33.8% +/- 2.8%, 28.0% +/- 3.0%, end 29.4% +/- 2.5%, respectively), as did serum cholesterol. Oral glucose tolerance initially deteriorated at 6 months, but improved toward the control value by 24 months. Fasting insulin (FI) increased significantly, as did the acute insulin response to oral glucose (Delta AIR(OGTT)/Delta G) at 30 minutes (FI: pretreatment 9.8 +/- 0.8, 6 months, 14.0 +/- 1.8, 24 months 12.5 +/- 1.6 v control 11.4 +/- 1.9 mU . L-1;Delta AIR(OGTT)/Delta G: pretreatment 201 +/- 24, 6 months 356 +/- 41, 24 months 382 +/- 86 v control 280 +/- 47 mU . mmol(-1)). However, the acute insulin response to intravenous (IV) glucose (AIR(G)) and IV glucagon at euglycemia and hyperglycemia did not change with rhGH therapy and were similar to the control group values. Importantly, the expected reciprocal relationships (as observed for the control group) between the various insulin secretory parameters and insulin sensitivity (SI) either were not present or were statistically weak in GHD subjects, despite the 35% decrease in SI by 24 months of rhGH therapy. In particular, over time, there was an attenuation of insulin secretion with respect to the ongoing insulin resistance with rhGH therapy, particularly for AIRG at 24 months. After 5 days of rhGH withdrawal, insulin secretion decreased and SI improved in GHD subjects. It is concluded that the current long-term rhGH treatment regimens appear to impact on insulin secretion such th

关键词：身体成分用药计划表葡萄糖钳制技术生长障碍/血液生长障碍/药物疗法生长障碍/代谢人生长激素/投药和剂量人生长激素/缺乏人生长激素/治疗应用胰岛素/血液胰岛素/代谢重组蛋白质类/治疗应用时间因素成年人女(雌)性人类男(雄)性

来源：评论

学校读者我要写书评

暂无评论

Low-dose contraceptive estrogen-progestin and coronary artery atherosclerosis of monkeys

引用

OBSTETRICS AND GYNECOLOGY 2000年第2期96卷 250-255页

作者： Adams, MR Anthony, MS Manning, JM Golden, DL Parks, JS Wake Forest Univ Sch Med Dept Pathol Comparat Med Winston Salem NC 27157 USA William Paterson Univ Dept Exercise & Movement Sci Wayne NJ USA

Objective: To determine the separate and combined effects of the estrogen and progestin components of a modern triphasic oral contraceptive (OC) formulation on extent of coronary artery atherosclerosis. Methods: Female cynomolgus monkeys (n = 81) were fed atherogenic diets for 32 months. After the first 7 months, they were randomized to four groups and treated triphasically for 21 of each 28 days with ethinyl estradiol (E2) (monkey equivalent of 30-40 pg), levonorgestrel (monkey equivalent of 50-125 mu g), a combination of the two steroids, or placebo. Results: Treatment with estrogen alone reduced coronary artery atherosclerosis extent 67% compared with untreated controls (P < .05). Treatment with progestin alone had no effect (P > .20). While atherosclerosis extent in monkeys treated with the combined OC was reduced 28%, this did not differ statistically from the other groups (P > .20). Conclusion: In doses used for oral contraception, E2, like all other estrogens studied to date, has a marked inhibitory effect on atherosclerosis progression. Levonorgestrel, at doses used in modern OC formulations, antagonizes this effect. When considered with other experimental evidence, these findings support the concept that progestins used in OCs and hormone replacement therapy can antagonize estrogen's atheroinhibitory effects. Whether this occurs seems to depend on a relative balance between estrogen and progestin with respect to dose, potency, route, and pattern of administration. However, when considered with evidence from previous studies, the findings also indicate a modest atheroinhibitory influence of combination (estrogen-progestin) OCs. ((C) 2000 by The American College of Obstetricians and Gynecologists.).

关键词：避孕药口服复合/投药和剂量避孕药口服复合/治疗应用冠状动脉疾病/预防和控制疾病模型动物用药计划表雌二醇同源物/投药和剂量雌二醇同源物/治疗应用炔雌醇/投药和剂量炔雌醇/治疗应用左炔诺孕酮/投药和剂量左炔诺孕酮/治疗应用脂蛋白类/血液成束猴孕酮同源物/投药和剂量孕酮同源物/治疗应用随机分配动物女(雌)性

来源：评论

学校读者我要写书评

暂无评论

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案：

请选择收藏分类：

通借通还

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：