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检索条件"主题词=神经组织蛋白质类/生理学"
81 条 记 录,以下是1-10 订阅
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Vascular developmental biology: getting nervous
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CURRENT OPINION IN GENETICS & DEVELOPMENT 2000年 第5期10卷 536-542页
作者: Shima, DT Mailhos, C Imperial Canc Res Fund Endothelial Cell Biol Lab London WC2A 3PX England Imperial Canc Res Fund Dev Genet Lab London WC2A 3PX England
First described in the developing nervous system, Semaphorin III/Neuropilin, Ephrin/Eph, and Delta/Notch signaling relays have now been implicated in the elaboration of the blood vessel network during embryogenesis.
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Synaptic assembly of the brain in the absence of neurotransmitter secretion
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SCIENCE 2000年 第5454期287卷 864-869页
作者: Verhage, M Maia, AS Plomp, JJ Brussaard, AB Heeroma, JH Vermeer, H Toonen, RF Hammer, RE van den Berg, TK Missler, M Geuze, HJ Südhof, TC Univ Utrecht Med Ctr Rudolf Magnus Inst Utrecht Netherlands Univ Texas SW Med Ctr Howard Hughes Med Inst Ctr Basic Neurosci Dallas TX 75235 USA Univ Texas SW Med Ctr Dept Mol Genet Dallas TX 75235 USA Leiden Univ Med Ctr Dept Neurol Leiden Netherlands Leiden Univ Med Ctr Dept Physiol Leiden Netherlands Vrije Univ Amsterdam Inst Neurosci Dept Neurophysiol Amsterdam Netherlands Univ Texas SW Med Ctr Dept Biochem Dallas TX 75235 USA Vrije Univ Amsterdam Dept Cell Biol & Immunol Amsterdam Netherlands Univ Utrecht Dept Cell Biol Utrecht Netherlands
Brain function requires precisely orchestrated connectivity between neurons. Establishment of these connections is believed to require signals secreted from outgrowing axons, followed by synapse formation between sele... 详细信息
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Wind-up of spinal cord neurones and pain sensation: much ado about something?
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PROGRESS IN NEUROBIOLOGY 2000年 第2期61卷 169-203页
作者: Herrero, JF Laird, JMA Lopez-Garcia, JA Univ Alcala de Henares Dept Fisiol Madrid 28871 Spain
Wind-up is a frequency-dependent increase in the excitability of spinal cord neurones, evoked by electrical stimulation of afferent C-fibres. Although it has been studied over the past thirty years, there are still un... 详细信息
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Synaptophysin regulates clathrin-independent endocytosis of synaptic vesicles
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2000年 第11期97卷 6120-6125页
作者: Daly, C Sugimori, M Moreira, JE Ziff, EB Llinás, R NYU Med Ctr Dept Physiol & Neurosci New York NY 10016 USA NYU Med Ctr Howard Hughes Med Inst New York NY 10016 USA NYU Med Ctr Dept Biochem New York NY 10016 USA Marine Biol Lab Woods Hole MA 02543 USA Univ Sao Paulo Ribeirao Preto Med Sch Dept Morphol BR-05508 Sao Paulo Brazil
The GTPase dynamin I is required for synaptic vesicle (SV) endocytosis, Our observation that dynamin binds to the SV protein synaptophysin in a Ca2+-dependent fashion suggested the possibility that a dynamin/synaptoph... 详细信息
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Proteomic analysis of NMDA receptor-adhesion protein signaling complexes
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NATURE NEUROSCIENCE 2000年 第7期3卷 661-669页
作者: Husi, H Ward, MA Choudhary, JS Blackstock, WP Grant, SGN Univ Edinburgh Ctr Neurosci Ctr Genome Res Edinburgh EH9 3JQ Midlothian Scotland Glaxo Wellcome Res & Dev Ltd Stevenage SG1 2NY Herts England
N-methyl-D-aspartate receptors (NMDAR) mediate long-lasting changes in synapse strength via downstream signaling pathways. We report proteomic characterization with mass spectrometry and immunoblotting of NMDAR multip... 详细信息
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Loss of autoreceptor functions in mice lacking the dopamine transporter
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NATURE NEUROSCIENCE 1999年 第7期2卷 649-655页
作者: Jones, SR Gainetdinov, RR Hu, XT Cooper, DC Wightman, RM White, FJ Caron, MG Duke Univ Med Ctr Dept Cell Biol Howard Hughes Med Inst Durham NC 27710 USA Finch Univ Hlth Sci Chicago Med Sch N Chicago IL 60064 USA Univ N Carolina Dept Chem Chapel Hill NC 27599 USA Univ N Carolina Curriculum Neurobiol Chapel Hill NC 27599 USA
Autoreceptors provide an important inhibitory feedback mechanism for dopamine neurons by altering neuronal functions in response to changes in extracellular levels of dopamine. Elevated dopamine may be a component of ... 详细信息
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Dopamine transporters participate in the physiological regulation of prolactin
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ENDOCRINOLOGY 2000年 第1期141卷 366-374页
作者: Demaria, JE Nagy, GM Lerant, AA Fekete, MIE Levenson, CW Freeman, ME Florida State Univ Dept Biol Sci Tallahassee FL 32306 USA Florida State Univ Dept Nutr Food & Exercise Sci Program Neurosci Tallahassee FL 32306 USA Semmelweis Univ Neuroendocrine Res Lab Dept Human Morphol & Embryol H-1085 Budapest Hungary Hungarian Acad Sci Inst Expt Med Budapest Hungary
Three populations of hypothalamic neuroendocrine dopaminergic (NEDA) neurons, arising from the arcuate and periventricular nuclei of the hypothalamus release dopamine (DA) that acts at the pituitary gland to regulate ... 详细信息
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Slit branches out: A secreted protein mediates both attractive and repulsive axon guidance
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CELL 1999年 第1期97卷 1-4页
作者: Zinn, K Sun, Q CALTECH Div Biol Pasadena CA 91125 USA
Investigates the potential relationship between the extracellular matrix protein Slit and Robo as receptor in the extracellular matrix. Binding to Robo-expressing cells in fly and vertebrate proteins; Slit's repul... 详细信息
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G-protein-independent signaling by G-protein-coupled receptors
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TRENDS IN NEUROSCIENCES 2000年 第10期23卷 469-475页
作者: Heuss, C Gerber, U Univ Zurich Brain Res Inst CH-8057 Zurich Switzerland
Two classes of receptors transduce neurotransmitter signals: ionotropic receptors and heptahelical metabotropic receptors. Whereas the ionotropic receptors are structurally associated with a membrane channel, a mediat... 详细信息
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(Over)correction of FMR1 deficiency with YAC transgenics: behavioral and physical features
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HUMAN MOLECULAR GENETICS 2000年 第8期9卷 1145-1159页
作者: Peier, AM McIlwain, KL Kenneson, A Warren, ST Paylor, R Nelson, DL Baylor Coll Med Dept Mol & Human Genet Houston TX 77030 USA Emory Univ Sch Med Dept Chem Atlanta GA 30322 USA Emory Univ Sch Med Howard Hughes Med Inst Atlanta GA 30322 USA
Fragile X syndrome is a common cause of mental retardation involving loss of expression of the FMR1 gene. The role of FMR1 remains undetermined but the protein appears to be involved in RNA metabolism. Fmr1 knock-out ... 详细信息
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