咨询与建议

限定检索结果

文献类型

  • 17 篇 期刊文献

馆藏范围

  • 17 篇 电子文献
  • 0 种 纸本馆藏

日期分布

学科分类号

  • 14 篇 医学
    • 10 篇 药学(可授医学、理...
    • 5 篇 临床医学
    • 2 篇 中西医结合
  • 4 篇 理学
    • 3 篇 生物学
  • 2 篇 工学
    • 1 篇 仪器科学与技术
  • 1 篇 农学
    • 1 篇 作物学

主题

  • 17 篇 血管舒张药/代谢
  • 12 篇 人类
  • 11 篇 男(雄)性
  • 9 篇 中年人
  • 7 篇 女(雌)性
  • 5 篇 血管舒张药/药代动...
  • 5 篇 四唑类/药代动力学...
  • 5 篇 四唑类/代谢
  • 5 篇 投药
  • 5 篇 口服
  • 5 篇 曲线下面积
  • 4 篇 血管舒张药/血液
  • 4 篇 成年人
  • 4 篇 血管舒张药/药理学...
  • 4 篇 四唑类/投药和剂量...
  • 4 篇 血管舒张药/投药和...
  • 4 篇 肽类/代谢
  • 4 篇 大鼠
  • 4 篇 动物
  • 4 篇 半衰期

机构

  • 5 篇 otsuka amer phar...
  • 2 篇 tohoku univ sch ...
  • 2 篇 tohoku univ sch ...
  • 2 篇 queens univ fac ...
  • 1 篇 miyazaki med col...
  • 1 篇 univ pisa dipart...
  • 1 篇 daiichi coll pha...
  • 1 篇 univ occupat & e...
  • 1 篇 miyazaki med col...
  • 1 篇 natl cardiovasc ...
  • 1 篇 massachusetts ge...
  • 1 篇 miyazaki med col...
  • 1 篇 karolinska inst ...
  • 1 篇 inst rech servie...
  • 1 篇 dept biomed sci ...
  • 1 篇 diagnost sci div...
  • 1 篇 hosp ramon y caj...
  • 1 篇 tohoku univ sch ...
  • 1 篇 univ dusseldorf ...
  • 1 篇 duke univ med ct...

作者

  • 5 篇 bramer sl
  • 3 篇 forbes wp
  • 2 篇 shibahara s
  • 2 篇 takahashi k
  • 2 篇 kitamura k
  • 2 篇 udono t
  • 2 篇 tamai m
  • 2 篇 suri a
  • 1 篇 takano s
  • 1 篇 marsen ta
  • 1 篇 fernández a
  • 1 篇 sato m
  • 1 篇 abe t
  • 1 篇 sukau g
  • 1 篇 yamashita h
  • 1 篇 baldamus ca
  • 1 篇 kangawa k
  • 1 篇 letts lg
  • 1 篇 marutsuka k
  • 1 篇 ratz jd

语言

  • 17 篇 英文
检索条件"主题词=血管舒张药/代谢"
17 条 记 录,以下是11-20 订阅
排序:
Effects of the flavoprotein inhibitor, diphenyleneiodonium sulfate, on ex vivo organic nitrate tolerance in the rat
收藏 引用
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 2000年 第2期293卷 569-577页
作者: Ratz, JD McGuire, JJ Anderson, DJ Bennett, BM Queens Univ Fac Hlth Sci Dept Pharmacol & Toxicol Kingston ON K7L 3N6 Canada
The flavoprotein inhibitor, diphenyleneiodonium (DPI), inhibits the action of glyceryl trinitrate (GTN) and the D-enantiomer of isoidide dinitrate (IIDN), but not the L-enantiomer (L-IIDN), in isolated rat aorta via i... 详细信息
来源: 评论
Nociceptin/orphanin FQ metabolism and bioactive metabolites
收藏 引用
PEPTIDES 2000年 第7期21卷 919-922页
作者: Terenius, L Sandin, J Sakurada, T Karolinska Inst Karolinska Hosp Dept Clin Neurosci Expt Alcohol & Drug Addict S-17176 Stockholm Sweden Daiichi Coll Pharmaceut Sci Dept Biochem Minami Ku Fukuoka 8158511 Japan
Thr endogenous ligand for the orphan NOR receptor (earlier named ORL1) was recently discovered. This ligand, nociceptin/orphanin FQ is involved in a number of pharmacological actions in the CNS, including modulation o... 详细信息
来源: 评论
Inhibition of CYP2D6 by quinidine and its effects on the metabolism of cilostazol
收藏 引用
CLINICAL PHARMACOKINETICS 1999年 第2-Sup期37卷 41-51页
作者: Bramer, SL Suri, A Otsuka Amer Pharmaceut Inc Dept Clin Pharmacokinet Pharmacodynam & Metab Rockville MD 20850 USA
Objective: In vitro results are inconclusive as to whether cilostazol is metabolised by cytochrome P450 isoenzyme 2D6 (CYP2D6). The goals of this study were (1) to assure the dose of quinidine and timing relative to c... 详细信息
来源: 评论
Enalapril and losartan augment endogenous nitric oxide release in Takayasu's arteritis - A case report
收藏 引用
ANGIOLOGY 2000年 第1期51卷 69-75页
作者: Marsen, TA Sukau, G Pollok, M Baldamus, CA Univ Cologne Klin Innere Med 4 D-50924 Cologne Lindenthal Germany
Prognosis in Takayasu's arteritis is limited owing to renovascular hypertension. The authors report a patient with Takayasu's arteritis,who had been unilaterally nephrectomized and presented with malignant hyp... 详细信息
来源: 评论
Trimetazidine:: a novel protective role via maintenance of Na+ /K+-ATPase activity?
收藏 引用
CARDIOVASCULAR RESEARCH 2000年 第4期47卷 637-639页
作者: Cross, HR Duke Univ Med Ctr Dept Pathol Durham NC 27710 USA
来源: 评论
Increased expression of adrenomedullin mRNA in the tissues of intraocular and orbital tumors
收藏 引用
AMERICAN JOURNAL OF OPHTHALMOLOGY 2000年 第4期129卷 555-556页
作者: Udono, T Totsune, K Takahashi, K Abe, T Sato, M Shibahara, S Tamai, M Tohoku Univ Sch Med Dept Mol Biol & Appl Physiol Aoba Ku Sendai Miyagi 9808575 Japan Tohoku Univ Sch Med Dept Ophthalmol Aoba Ku Sendai Miyagi 9808575 Japan Tohoku Univ Sch Med Dept Internal Med 2 Aoba Ku Sendai Miyagi 9808575 Japan
PURPOSE: To explore the possible involvement of ade renomedullin in the pathophysiology of intraocular and orbital tumors. METHODS: Competitive reverse transcription-polymerase chain reaction was used to determine adr... 详细信息
来源: 评论
Glyceryl trinitrate-induced vasodilation is inhibited by ultraviolet irradiation despite enhanced nitric oxide generation: Evidence for formation of a nitric oxide conjugate
收藏 引用
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 1999年 第2期289卷 895-900页
作者: Hussain, AS Crispino, NH McLaughlin, BE Brien, JF Marks, GS Nakatsu, K Queens Univ Fac Hlth Sci Dept Pharmacol & Toxicol Kingston ON K7L 3N6 Canada
Our objective was to determine whether a stabilized form of nitric oxide (NO) such as an S-nitrosothiol, rather than NO itself, is the vasoactive metabolite produced when glyceryl trinitrate (GTN) interacts with vascu... 详细信息
来源: 评论