We report the case of a 33-year-old patientwho had had insulindependent diabetes mellitus (IDDM) since he was 11 months old, and who presented with major perforating necrobiosis lipoidica (PNL) complicated by a well-d...
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We report the case of a 33-year-old patientwho had had insulindependent diabetes mellitus (IDDM) since he was 11 months old, and who presented with major perforating necrobiosis lipoidica (PNL) complicated by a well-differe-ntiated epidermoid carcinoma. PNL is a rare clinical form of NL, always associated with diabetes. Only seven cases have been reported to date in the literature, and to the best of our knowledge, an association of epidermoid carcinoma and PNL has never been described. The development of a tumoral transformation on a classical NL plaque has only been described 12 times. The presence of an epidermoid carcinoma on a weakened background with permanent ulceration suggests that early surgical excision of the tumour and of the NL followed by a skin graft might be the treatment of choice. Radiotherapy seems to be a poor therapeutic option.
支气管粘液表皮样癌(mucoepidermoid carcinoma of bronchus)是较为罕见的肺部肿瘤之一, 它起源于气管、支气管粘膜下腺体的Kulchitsky细胞,生长缓慢、恶性程度相对较低,占原发性肺癌的0.1%~0.2%,较原发性支气管肺癌恶性程度低[1]。临...
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支气管粘液表皮样癌(mucoepidermoid carcinoma of bronchus)是较为罕见的肺部肿瘤之一, 它起源于气管、支气管粘膜下腺体的Kulchitsky细胞,生长缓慢、恶性程度相对较低,占原发性肺癌的0.1%~0.2%,较原发性支气管肺癌恶性程度低[1]。临床表现不典型,发展缓慢。支气管镜是其主要诊断方法,有些病灶分布在边缘细支气管,常规气管镜检查无法获取病理。现报告本科在CT引导下经皮肺穿刺病理活检确诊的1例并文献复习。
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