Nonsustained ventricular tachycardia(NSVT) is a well-recognized side effect during dobutamine stress echocardiography(DSE). This study sought to evaluate the prognostic implications of NSVT during DSE on 1,266 consecu...
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Nonsustained ventricular tachycardia(NSVT) is a well-recognized side effect during dobutamine stress echocardiography(DSE). This study sought to evaluate the prognostic implications of NSVT during DSE on 1,266 consecutive dobutamine stress echocardiograms performed over 1 year. NSVT, defined as< 3 consecutive ventricular premature beats, occurred in 65 of 1,266 patients(5.1% ). There was no absolute increased risk in all-cause mortality between the NSVT and no NSVT groups(22% vs 17% , p=0.15) during the 3-year follow-up. Survival curves generated by the Kaplan-Meier method also demonstrated no increased risk in mortality between the NSVT and no NSVT groups(p=0.43). When only studies with negative results for inducible ischemia were taken into account, survival curves showed no significant difference in all-cause mortality(p=0.26). Studies with negative results for inducible ischemia were also stratified according to the ejection fraction(EF). Patients without inducible ischemia and mildly reduced to normal EFs( >0.45) did not have significant differences in survival between the NSVT and no NSVT groups over the 3-year follow-up(p=0.86). However, patients without inducible ischemia and moderately reduced EFs(0.35 to 0.45) who had NSVT during DSE had significantly reduced survival over the follow-up(p=0.01).
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