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检索条件"主题词=Additional Data File"
1087 条 记 录,以下是291-300 订阅
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Integrating computationally assembled mouse transcript sequences with the Mouse Genome Informatics (MGI) database
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GENOME BIOLOGY 2003年 第2期4卷 R16-R16页
作者: Zhu, YX King, BL Parvizi, B Brunk, BP Stoeckert, CJ Quackenbush, J Richardson, J Bult, CJ Jackson Lab Bar Harbor ME 04609 USA Invitrogen Corp Carlsbad CA 92008 USA Univ Penn Ctr Bioinformat Philadelphia PA 19104 USA Inst Genom Res Rockville MD 20850 USA
databases of experimentally generated and computationally derived transcript sequences are valuable resources for genome analysis and annotation. The utility of such databases is enhanced when the sequences they conta... 详细信息
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Assessing unmodified 70-mer oligonucleotide probe performance on glass-slide microarrays
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GENOME BIOLOGY 2003年 第1期4卷 R5-R5页
作者: Wang, HY Malek, RL Kwitek, AE Greene, AS Luu, TV Behbahani, B Frank, B Quackenbush, J Lee, NH Inst Genom Res Rockville MD 20850 USA Med Coll Wisconsin Dept Physiol Milwaukee WI 53226 USA George Washington Univ Med Ctr Dept Pharmacol Washington DC 20037 USA
Background: Long oligonucleotide microarrays are potentially more cost- and management-efficient than cDNA microarrays, but there is little information on the relative performance of these two probe types. The feasibi... 详细信息
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Identification of transcripts with enriched expression in the developing and adult pancreas
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GENOME BIOLOGY 2008年 第6期9卷 R99-R99页
作者: Hoffman, Brad G. Zavaglia, Bogard Witzsche, Joy de Algara, Teresa Ruiz Beach, Mike Hoodless, Pamela A. Jones, Steven J. M. Marra, Marco A. Helgason, Cheryl D. British Columbia Canc Res Ctr Dept Canc Endocrinol Vancouver BC V5Z 1L3 Canada British Columbia Canc Res Ctr Terry Fox Lab Vancouver BC V5Z 1L3 Canada Univ British Columbia Fac Med Dept Med Genet Vancouver BC V6T 1Z3 Canada Michael Smith Genome Sci Ctr BC Canc Agcy Vancouver BC V5Z 4S6 Canada Univ British Columbia Fac Med Dept Surg Vancouver BC V5Z 4E3 Canada
Background: Despite recent advances, the transcriptional hierarchy driving pancreas organogenesis remains largely unknown, in part due to the paucity of comprehensive analyses. To address this deficit we generated ten... 详细信息
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A systematic comparative and structural analysis of protein phosphorylation sites based on the mtcPTM database
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GENOME BIOLOGY 2007年 第5期8卷 R90-R90页
作者: Jimenez, Jose L. Hegemann, Bjoren Outchins, James R. A. Peters, Jan-Michael Durbin, Richard Wellcome Trust Sanger Inst Cambridge CB10 1SA England Res Inst Mol Pathol IMP A-1030 Vienna Austria
mtcPTM is an online repository of human and mouse phosphosites where the data are hierarchically organized to preserve biologically relevant experimental information, thus allowing straightforward comparisons of phosp... 详细信息
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Rapid transcriptome responses of maize (Zea mays) to UV-B in irradiated and shielded tissues -: art. no. R16
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GENOME BIOLOGY 2004年 第3期5卷 1-19页
作者: Casati, P Walbot, V Stanford Univ Dept Biol Sci Stanford CA 94305 USA
Background: Depletion of stratospheric ozone has raised terrestrial levels of ultraviolet-B radiation (UV-B), an environmental change linked to an increased risk of skin cancer and with potentially deleterious consequ... 详细信息
来源: 评论
Modeling synthetic lethality
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GENOME BIOLOGY 2008年 第9期9卷 R135-R135页
作者: Le Meur, Nolwenn Gentleman, Robert Fred Hutchinson Canc Res Ctr Div Publ Hlth Sci Program Computat Biol Seattle WA 98109 USA INSERM IRISA Symbiose F-35042 Rennes France
Background: Synthetic lethality defines a genetic interaction where the combination of mutations in two or more genes leads to cell death. The implications of synthetic lethal screens have been discussed in the contex... 详细信息
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Development and application of versatile high density microarrays for genome-wide analysis of Streptomyces coelicolor: characterization of the HspR regulon
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GENOME BIOLOGY 2009年 第1期10卷 R5-R5页
作者: Bucca, Giselda Laing, Emma Mersinias, Vassilis Allenby, Nicholas Hurd, Douglas Holdstock, Jolyon Brenner, Volker Harrison, Marcus Smith, Colin P. Univ Surrey Fac Hlth & Med Sci Microbial Sci Div Guildford GU2 7XH Surrey England Oxford Gene Technol Ltd Oxford OX15 1PF England
Background: DNA microarrays are a key resource for global analysis of genome content, gene expression and the distribution of transcription factor binding sites. We describe the development and application of versatil... 详细信息
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Increased cardiac index due to terbutaline treatment aggravates capillary-alveolar macromolecular leakage in oleic acid lung injury in dogs
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CRITICAL CARE 2009年 第5期13卷 R166-R166页
作者: Briot, Raphael Bayat, Sam Anglade, Daniel Martiel, Jean-Louis Grimbert, Francis Univ Grenoble 1 Ctr Hosp Univ CNRS Lab TIMCEquipe PRETAUMR 5525 F-38043 Grenoble 09 France
Introduction We assessed the in vivo effects of terbutaline, a beta2-agonist assumed to reduce microvascular permeability in acute lung injury. Methods We used a recently developed broncho-alveolar lavage (BAL) techni... 详细信息
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Cell-specific microarray profiling experiments reveal a comprehensive picture of gene expression in the C-elegans nervous system
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GENOME BIOLOGY 2007年 第7期8卷 R135-R135页
作者: Von Stetina, Stephen E. Watson, Joseph D. Fox, Rebecca M. Olszewski, Kellen L. Spencer, W. Clay Roy, Peter J. Miller, David M., III Vanderbilt Univ Dept Cell & Dev Biol Nashville TN 37232 USA Vanderbilt Univ Ctr Mol Neurosci Grad Program Neurosci Nashville TN 37232 USA Johns Hopkins Univ Sch Med Dept Cell Biol Baltimore MD 21205 USA Princeton Univ Lewis Sigler Inst Integrat Genom Dept Mol Biol Princeton NJ 08544 USA Univ Toronto Donnelly Ctr Cellular & Biomol Res Dept Med Genet & Microbiol Toronto ON M5S 1A Canada
Background: With its fully sequenced genome and simple, well-defined nervous system, the nematode Caenorhabditis elegans offers a unique opportunity to correlate gene expression with neuronal differentiation. The line... 详细信息
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Development of a 950-gene DNA array for examining gene expression patterns in mouse testis
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GENOME BIOLOGY 2001年 第4期2卷 research0014.1-research0014.9页
作者: Rockett, John C. Luft, J. Christopher Garges, J. Brian Krawetz, Stephen A. Hughes, Mark R. Kim, Kwan Hee Oudes, Asa J. Dix, David J. US EPA Natl Hlth & Environm Effects Res Lab Reprod Toxciol Div Res Triangle Pk NC 27711 USA Wayne State Univ Sch Med Ctr Mol Med & Genet Detroit MI 48201 USA Wayne State Univ Sch Med Dept Obstet & Gynecol Detroit MI 48201 USA Washington State Univ Sch Mol Biosci Pullman WA 99164 USA
Background: Over the past five years, interest in and use of DNA array technology has increased dramatically, and there has been a surge in demand for different types of arrays. Although manufacturers offer a number o... 详细信息
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