The treatment of "time" is discussed as both a syntactic & a grammatical category by the Indian grammatical tradition. Some objections raised by the Buddhists to the views of Bhartrhari & the Paniniy...
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The treatment of "time" is discussed as both a syntactic & a grammatical category by the Indian grammatical tradition. Some objections raised by the Buddhists to the views of Bhartrhari & the Paniniyas are described & answered. Among these are the validity of the concept of present time. This contrasts with the Buddhist view of time as moments in a flow, with no permanence or persistence. 52 References. Adapted from the source document
The complete peptide map of purified recombinant human interleukin 5 (rhIL-5) was determined to verify its primary structure, glycosylation sites, and disulfide bonding structure. Each peptide fragment generated by Ac...
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The complete peptide map of purified recombinant human interleukin 5 (rhIL-5) was determined to verify its primary structure, glycosylation sites, and disulfide bonding structure. Each peptide fragment generated by Achromobacter protease I (API) digestion was purified and characterized by amino acid analysis and amion acid sequence analysis. After digestion with API, we could identify all the peptides which were expected from human IL-5 cDNA sequence. The analyses of sulfhydryl content in rhIL-5 molecule and disulfide-containing peptide obtained from API digestion indicated that active form of rhIL-5 existed as an antiparallel dimer linked by two pairs of Cys-44 and Cys-86. In addition, we concluded that Thr-3 and Asn-28 were glycosylated. The results indicate that primary structure of rhIL-5 is highly homogeneous and observed heterogeneity is due to the difference in the content of carbohydrate.
The activated c-Ha-ras oncogene induced AP1-site DNA-binding activity in F9 cells. This induction appeared to be due, at least in part, to the induction of c-jun transcription. Both activated c-Ha-ras and c-jun induce...
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The activated c-Ha-ras oncogene induced AP1-site DNA-binding activity in F9 cells. This induction appeared to be due, at least in part, to the induction of c-jun transcription. Both activated c-Ha-ras and c-jun induced the differentiation of F9 cells to endoderm-like cells. Thus, AP1 appears to play a key role in the initial stage of F9 cell differentiation.
Reproducible and discriminating typing methods are required for epidemiological investigations. Numerical typing systems analyse patterns obtained in various ways by calculating similarity coefficients between isolate...
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Reproducible and discriminating typing methods are required for epidemiological investigations. Numerical typing systems analyse patterns obtained in various ways by calculating similarity coefficients between isolates. In the present study, various measures of the efficiency of a numerical typing system are quantified. These include reproducibility, accuracy, and discrimination power. Three different numerical typing methods for Escherichia coli were compared using these measures: (a) Biotyping with API 50 CH system, (b) Biochemical fingerprinting with the API 50 CH system and (c) Biochemical fingerprinting with the PhP-EC system. Biotyping qualitatively measures the results of a set of biochemical reactions as + or -. Biochemical fingerprinting also uses biochemical reactions, but the tests are scored quantitatively by measuring the kinetics and intensity of each reaction. It was found that biotyping yielded poor reproducibility. When biochemical fingerprinting analysis was used with the API 50 CHE system the reproducibility and the discrimination was good. The PhP-EC system for biochemical fingerprinting showed equal reproducibility but was superior to the API 50 CH system with regard to discrimination power.
smg p21A and -B are small GTP-binding proteins that share putative effector and consensus C-terminal sequences with ras p21 proteins. In the present report, we showed that human platelet smg p21B became labeled when i...
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smg p21A and -B are small GTP-binding proteins that share putative effector and consensus C-terminal sequences with ras p21 proteins. In the present report, we showed that human platelet smg p21B became labeled when intact platelets were incubated with exogenous [3H]mevalonolactone and when a purified preparation of smg p21B was incubated with bovine brain membranes and S-adenosyl-L-[methyl-3H]methionine. In addition, we demonstrated by gas chromatography/mass spectrometry that treatment of smg p21B with Raney nickel released a geranylgeranyl moiety in a molar ratio of about 1:1. In contrast, treatment of smg p21B with NH2OH or KOH yielded no evidence for the presence of a palmitoyl thioester. Extensive digestion of smg p21B with Achromobacter protease I yielded two C-terminal tripeptides that contained serine and cysteine in a molar ratio of 2:1. Both peptides were modified by a thioether-linked geranylgeranyl group. One of the peptides comigrated with a 3H-labeled proteolytic product of methylated smg p21B on reverse-phase HPLC and this peptide appeared at the same retention time as that of the other peptide after being treated with KOH. Since the cDNA-predicted C-terminal sequence of smg p21B contains a unique Ser-Ser-Cys peptide within its C-terminal domain, -Lys-Lys-Ser-Ser-Cys-Gln-Leu-Leu184, these results indicate that smg p21B is posttranslationally modified by geranylgeranylation of Cys-181 and suggest that further modifications cause proteolytic removal of the three predicted C-terminal amino acids followed by partial methylation of the cysteinyl carboxyl group.
The evidence for the date and significance of various monuments uncovered in the ‘Embalming House of the Apis Bulls’ is reviewed in the light of recent excavations there. It is suggested that the latest building lev...
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The evidence for the date and significance of various monuments uncovered in the ‘Embalming House of the Apis Bulls’ is reviewed in the light of recent excavations there. It is suggested that the latest building level dates to the fourth century bc and can be equated with the major renovation undertaken by Nectanebo II, as described on a stela of his year 2 now in the Cairo Museum. In particular, a newly-discovered inscription on a vessel found in situ identifies the site, or some part of it, as the w'bt of the temple of Apis. The fourth-century structure was built on a platform, into the foundations of which were incorporated blocks of Shabako, usurped by Psamtek II. These probably came from the building described by Herodotus II, 153.
Whilst there have been claims that the success rate has been near 30 per cent, the realistic success rate is near 3 per cent. Due to the poor success rate, the Chinese petroleum authorities are now likely to consider ...
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Whilst there have been claims that the success rate has been near 30 per cent, the realistic success rate is near 3 per cent. Due to the poor success rate, the Chinese petroleum authorities are now likely to consider all proposals of offshore exploration.
A. N. Kolmogorov and A. Renyi both presuppose a Boolean algebra in their accounts of an absolute probability space, but Karl Popper does not. A review of the accounts of an absolute probability space put forward b...
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A. N. Kolmogorov and A. Renyi both presuppose a Boolean algebra in their accounts of an absolute probability space, but Karl Popper does not. A review of the accounts of an absolute probability space put forward by Kolmogorov, Renyi and Popper is offered.
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