We consider optimization of batch data processing if there are two alternative processing methods available with different unknown efficiencies. One should determine more efficient method and provide its predominant u...
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We consider optimization of batch data processing if there are two alternative processing methods available with different unknown efficiencies. One should determine more efficient method and provide its predominant usage. Formally, the problem is presented as Gaussian two-armed bandit problem with a priori unknown mathematical expectations and variances of incomes. We consider the problem in robust (minimax) setting. According to the main theorem of game theory, minimax strategy and minimax risk are sought for as Bayesian ones corresponding to the worst-case prior distribution of parameter. We describe the properties of the worst-case prior distribution and present corresponding recursive equations for determining Bayesian risk and expected losses. Some numerical examples are presented. We show that the control performance almost does not depend on the number of processed batches if this number is large enough.
In many operations time factor is a main constraint. Being able to optimally execute them while minimizing the amount of resources used remain a challenge in many business areas. In this paper we propose a model to op...
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We develop the UCB strategy for the two-armed bandit problem. When a player chooses an arm, he receives a one-step random income. But the player does not know which of the arms is more profitable. To solve this proble...
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We consider optimization of moderate batch data processing in the framework of Bernoulli two-armed bandit problem with indefinite control horizon. We assume that there are two alternative processing methods with diffe...
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We consider the minimax setup for Gaussian one-armed bandit problem, i.e. the two-armed bandit problem with Gaussian distributions of incomes and known distribution corresponding to the first arm. This setup naturally...
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Grading process is a critical yet intricate task for educators. This research addresses the inefficiencies and complexities inherent in the current manual grading approach, focusing on the challenges faced by educator...
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alpha-Alkylidene cyclic carbonates (alpha CCs) are gaining interest as building blocks in organic and polymer chemistry. To date, their synthesis via the coupling of CO2 to propargylic alcohols has been restricted to ...
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alpha-Alkylidene cyclic carbonates (alpha CCs) are gaining interest as building blocks in organic and polymer chemistry. To date, their synthesis via the coupling of CO2 to propargylic alcohols has been restricted to batch processes, with extensive efforts devoted to improving catalytic systems. Herein, utilizing a refined, homogeneous silver-carbene-organobase catalytic system, we optimized batch conditions to achieve, for the first time, complete conversion of tertiary propargylic alcohols within minutes instead of hours. Building on this, we introduce a continuous flow methodology to produce a library of alpha CCs, achieving the highest space-time yields reported, with quantitative conversions in less than 20 minutes and outputs up to 111 grams per day. This approach reduces CO2 usage to 1 or 2 equivalents, improves parameter control, and is expected to facilitate scalability. In addition, "plug-and-play" lab-scale continuous flow modules enable seamless integration of subsequent alpha CC transformations without intermediate purification, as illustrated by the aminolysis of alpha CCs into oxazolidones with good conversion (91%). Furthermore, supporting the silver-carbene catalyst on a polymer matrix eliminates silver contamination and even suppresses the need for a base co-catalyst. This work advances the scalable synthesis of alpha CCs via continuous flow, marking a significant step toward greener, CO2-based cyclic carbonates and derivatives.
Research on cells and organ-like tissues is critical in the fields of molecular biology, genetic analysis, proteomics analysis, tissue engineering, and others. In recent years, advancements in precise cell manipulatio...
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Research on cells and organ-like tissues is critical in the fields of molecular biology, genetic analysis, proteomics analysis, tissue engineering, and others. In recent years, advancements in precise cell manipulation technologies have made precise positioning and batchprocessing of cells feasible. Various methods are used for cell recognition, positioning, manipulation, and assembly, often introducing external fields such as electric, magnetic, acoustic, or optical fields into the liquid environment to interact with cells, applying forces to induce cell movement and rearrangement. Alternatively, three-dimensional (3D) bioprinting technology is employed for precise cell positioning and assembly. This review will comprehensively assess the status, principles, advantages, disadvantages, and prospects of these precise cell manipulation technologies, covering single-cell manipulation, multicellular assembly, and biological 3D printing techniques.
batch processes are important manufacturing process. data-driven soft sensor has become an essential means to measure key process variables of batch processes online. However, due to the complex characteristics of bat...
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The fashion clothing apparel sector operates in a dynamic environment, subject to seasonal changes in the collection. There are at least two collection every year, consisting in tight windows for production. Moreover,...
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