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检索条件"主题词=Bnip3"
514 条 记 录,以下是111-120 订阅
排序:
Evidence of oxidative stress-induced bnip3 expression in amyloid beta neurotoxicity
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BRAIN RESEARCH 2007年 第0期1138卷 221-230页
作者: Zhang, Surong Zhang, Zhengfeng Sandhu, Garry Ma, Xiuli Yang, Xuefen Geiger, Jonathan D. Kong, Jiming Univ Manitoba Fac Med Dept Human Anat & Cell Sci Winnipeg MB R3E 0W3 Canada Univ N Dakota Sch Med & Hlth Sci Dept Pharmacol Physiol & Therapeut Grand Forks ND 58203 USA
The formation of A beta and its subsequent deposition in senile plaques are considered to be initial events that lead to a cascade of pathological changes in AD. Mediators of A beta-induced oxidative stress are known ... 详细信息
来源: 评论
Platonin protects against cerebral ischemia/reperfusion injury in rats by inhibiting NLRP3 inflammasomes via bnip3/LC3 signaling mediated autophagy
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BRAIN RESEARCH BULLETIN 2022年 第0期180卷 12-23页
作者: Luo, Jing Tan, Junyi Jiang, Ning Yang, Changhong Chen, Jialei Zhao, Jing Li, Lingyu Zhao, Yong Chongqing Med Univ Dept Pathol Chongqing 400016 Peoples R China Chongqing Med Univ Dept Pathophysiol Chongqing 400016 Peoples R China Chongqing Med Univ Dept Bioinformat Chongqing 400016 Peoples R China Chongqing Med Univ Inst Neurosci Chongqing 400016 Peoples R China
Studies have found that Platonin has neuroprotective effect, but its molecular mechanism needs further study. We found that at the early stage of cerebral ischemia/reperfusion injury, Platonin treatment significantly ... 详细信息
来源: 评论
Autophagy and Bcl-2/bnip3 death regulatory pathway in non-small cell lung carcinomas
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APMIS 2013年 第7期121卷 592-604页
作者: Karpathiou, Georgia Sivridis, Efthimios Koukourakis, Michael Mikroulis, Dimitrios Bouros, Demosthenes Froudarakis, Marios Bougioukas, George Maltezos, Efstratios Giatromanolaki, Alexandra Democritus Univ Thrace Dept Pathol Sch Med Alexandroupolis 68100 Greece Democritus Univ Thrace Dept Radiotherapy Oncol Sch Med Alexandroupolis 68100 Greece Democritus Univ Thrace Dept Cardiac Thorac Surg Sch Med Alexandroupolis 68100 Greece Democritus Univ Thrace Dept Pneumonol Sch Med Alexandroupolis 68100 Greece Democritus Univ Thrace Dept Internal Med Sch Med Alexandroupolis 68100 Greece
We recently showed that non-small cell lung carcinomas (NSCLCs) are of dismal prognosis when encompassing accelerated autophagic activity. The regulation of this abnormally functioning degradation system and its assoc... 详细信息
来源: 评论
Bcl-2/adenovirus E1B 19 kDa-interacting protein 3 (bnip3) expression is epigenetically regulated by one-carbon metabolism in invasive duct cell carcinoma of breast
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MOLECULAR AND CELLULAR BIOCHEMISTRY 2012年 第1-2期361卷 189-195页
作者: Naushad, Shaik Mohammad Prayaga, Aruna Digumarti, Raghunadha Rao Gottumukkala, Suryanarayana Raju Kutala, Vijay Kumar Nizams Inst Med Sci Dept Clin Pharmacol & Therapeut Hyderabad 500082 Andhra Pradesh India Nizams Inst Med Sci Dept Pathol Hyderabad 500082 Andhra Pradesh India Nizams Inst Med Sci Dept Med Oncol Hyderabad 500082 Andhra Pradesh India Nizams Inst Med Sci Dept Surg Oncol Hyderabad 500082 Andhra Pradesh India
In view of recent studies highlighting the prognostic relevance of expression and CpG island methylator phenotype (CIMP) of Bcl-2/adenovirus E1B 19 kDa-interacting protein 3 (bnip3) in invasive duct cell carcinoma (ID... 详细信息
来源: 评论
Poorer outcome in stromal HIF-2α- and CA9-positive colorectal adenocarcinomas is associated with wild-type TP53 but not with bnip3 promoter hypermethylation or apoptosis
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BRITISH JOURNAL OF CANCER 2008年 第5期99卷 727-733页
作者: Cleven, A. H. G. Wouters, B. G. Schutte, B. Spiertz, A. J. G. van Engeland, M. de Bruine, A. P. Univ Hosp Dept Pathol GROW Sch Oncol & Dev Biol NL-6202 AZ Maastricht Netherlands Ontario Canc Inst PMH Toronto ON M4X 1K9 Canada Univ Hosp Dept Mol Cell Biol GROW Sch Oncol & Dev Biol NL-6202 AZ Maastricht Netherlands
Stromal expression of hypoxia inducible factor 2 alpha (HIF-2 alpha) and carbonic anhydrase 9 (CA9) are associated with a poorer prognosis in colorectal cancer (CRC). Tumour cell death, regulated by a hypoxic stromal ... 详细信息
来源: 评论
HIF-1α activation by a redox-sensitive pathway mediates cyanide-induced bnip3 upregulation and mitochondrial-dependent cell death
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FREE RADICAL BIOLOGY AND MEDICINE 2007年 第1期43卷 117-127页
作者: Zhang, L. Li, L. Liu, H. Prabhakaran, K. Zhang, X. Borowitz, J. L. Isom, G. E. Purdue Univ Dept Med Chem & Mol Pharmacol W Lafayette IN 47907 USA
Cyanide produces degeneration of the nervous system in which different modes of cell death are activated in the vulnerable brain areas. In brain, the mechanism underlying the cell death is not clear. In this study, an... 详细信息
来源: 评论
Synergism of arsenic trioxide and MG132 in Raji cells attained by targeting bnip3, autophagy, and mitochondria with low doses of valproic acid and vincristine
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EUROPEAN JOURNAL OF CANCER 2014年 第18期50卷 3243-3261页
作者: Cavaliere, Victoria Lombardo, Tomas Costantino, Susana N. Kornblihtt, Laura Alvarez, Elida M. Blanco, Guillermo A. UBA IDEHU CONICET Lab Inmunotoxicol LaITo Hosp Clin RA-1113 Buenos Aires DF Argentina UBA Fac Farm & Bioquim IDEHU CONICET LIT RA-1113 Buenos Aires DF Argentina UBA Hosp Clin Serv Hematol RA-1113 Buenos Aires DF Argentina
We previously demonstrated that arsenic trioxide (ATO) and proteasome inhibitor MG132 synergistically induced cell death in promonocytic leukaemia cell line U937 but were antagonistic in Burkitt's lymphoma cell li... 详细信息
来源: 评论
Semaglutide attenuates doxorubicin-induced cardiotoxicity by ameliorating bnip3-Mediated mitochondrial dysfunction
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REDOX BIOLOGY 2024年 72卷 103129页
作者: Li, Xiaoping Luo, Wenbin Tang, Yang Wu, Jiangjiao Zhang, Junkai Chen, Shengnan Zhou, Lu Tao, Yu Tang, Yuanjuan Wang, Fengxian Huang, Yu Jose, Pedro A. Guo, Li Zeng, Chunyu Third Mil Med Univ Army Med Univ Daping Hosp Dept Cardiol Chongqing Peoples R China Chongqing Inst Cardiol Chongqing Cardiovasc Clin Res Ctr Key Lab Geriatr Cardiovasc & Cerebrovasc Dis Res Chongqing Key Lab Hypertens ResMinist Educ China Chongqing Peoples R China Chongqing Univ Coll Bioengn Chongqing Peoples R China Southwest Jiaotong Univ Peoples Hosp Hosp Chengdu 3 Dept Cardiol Affiliated Hosp Chengdu Peoples R China City Univ Hong Kong Dept Biomed Sci Hong Kong Peoples R China George Washington Univ Div Renal Dis & Hypertens Sch Med & Hlth Sci Washington DC USA Army Med Univ Mil Med Univ 3 Endocrinol Dept Affiliated Hosp 1 Chongqing Peoples R China Third Mil Med Univ Daping Hosp State Key Lab Trauma Burns & Combined Injury Chongqing Peoples R China Univ Chinese Acad Sci Chinese Acad Sci Ctr Chongqing Coll Chongqing Peoples R China Kunming Med Univ Dept Cardiol Affiliated Hosp 1 Kunming Yunnan Peoples R China
Aims: Doxorubicin is a powerful chemotherapeutic agent for cancer, whose use is limited due to its potential cardiotoxicity. Semaglutide (SEMA), a novel analog of glucagon-like peptide-1 (GLP-1), has received widespre... 详细信息
来源: 评论
Expression of the cell death genes bnip3 and NIX in ductal carcinoma in situ of the breast;: correlation of bnip3 levels with necrosis and grade
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JOURNAL OF PATHOLOGY 2003年 第4期201卷 573-580页
作者: Sowter, HM Ferguson, M Pym, C Watson, P Fox, SB Han, C Harris, AL John Radcliffe Hosp Inst Mol Med Oxford OX3 9DS England John Radcliffe Hosp Nuffield Dept Clin Lab Sci Oxford England John Radcliffe Hosp Dept Histopathol Oxford OX3 9DU England Univ Manitoba Winnipeg MB R3E 0W3 Canada Churchill Hosp Dept Stat Oxford OX3 7LJ England
Ductal carcinoma in situ (DCIS) of the breast is an early, non-invasive lesion and the prognosis is associated with the extent of necrosis and cell death within the tumour. Two cell death genes, bnip3 and NIX, are up-... 详细信息
来源: 评论
Down-regulation of bnip3 by olomoucine, a CDK inhibitor, reduces LPS- and NO-induced cell death in BV2 microglial cells
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NEUROSCIENCE LETTERS 2016年 第0期628卷 186-193页
作者: Tsou, Yu-Chi Wang, Hsiao-Hsien Hsieh, Chii-Cheng Sun, Kuang-Hui Sun, Guang-Huan Jhou, Ren-Shiang Liu, Tz-I Lu, Shou-Yun Liu, Huan-Yun Tang, Shye-Jye Natl Taiwan Ocean Univ Dept Biosci & Biotechnol Ctr Excellence Oceans Keelung 20224 Taiwan Cheng Hsin Gen Hosp Urol Sect Taipei 11211 Taiwan Natl Yang Ming Univ Dept Biotechnol & Lab Sci Med Taipei 11211 Taiwan Taipei City Hosp Dept Educ & Res Taipei 100 Taiwan Triserv Gen Hosp Div Urol Dept Surg Natl Def Med Ctr Taipei 11100 Taiwan Taoyuan Armed Forces Gen Dept Surg Div Urol Taoyuan Taiwan
Proinflammatory responses eliciting the microglial production of cytokines and nitric oxide (NO) have been reported to play a crucial role in the acute and chronic pathogenic effects of neurodegeneration. Chemical inh... 详细信息
来源: 评论