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Static virtualization of c source code

SOFTWARE-PRAcTIcE & EXPERIENcE 2008年第4期38卷 397-416页

作者： Jansen, Sam McGregor, Anthony Univ Waikato Dept Comp Sci Hamilton New Zealand

Many existing systems are written in c and are not re-entrant or thread safe. Sometimes these systems are required in a context for which they were not first designed, possibly meaning they now need to be re-entrant. This article introduces a program that filters c source code, modifying shared resources (the global variables) to make the code re-entrant: 'virtualizing' the code. The code is then compiled as normal. This approach allows programmatic virtualization with little cost at runtime. copyright (c) 2007 John Wiley & Sons, Ltd.

关键词： virtualization c parsing static source

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Viscosity of Fe-Mn-c Melts

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RUSSIAN JOURNAL OF PHYSIcAL cHEMISTRY A 2021年第2期95卷 244-249页

作者： chikova, O. A. Sinitsin, N., I V'yukhin, V. V. Yeltsin Ural Fed Univ Ekaterinburg 620002 Russia Ural Pedag Univ Ekaterinburg 620017 Russia

The kinematic viscosity of Fe-Mn-c melts is measured with Mn contents of 5.0, 7.5, 10.0, 12.0, 15.0, 17.5, 20.0, and 25.0 wt % and c contents of 0.4 to 2.2 wt %. The kinematic viscosity is measured using damped torsional vibrations of a crucible with a melt upon the heating and subsequent cooling of the samples. The temperatures at which the characteristics of the viscous flow change and the liquid-liquid structural transition occurs in Fe-Mn-c melts are determined using the results from measuring the kinematic viscosity.

关键词： Fe– Mn– c viscosity theory of absolute reaction rates liquid– liquid structural transition Arrhenius– Frenkel– Eyring equation activation energy of viscous flow volume of viscous flow structural unit

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Adhesion Energy of c-elegans

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EXPERIMENTAL MEcHANIcS 2018年第8期58卷 1281-1289页

作者： Keller, M. W. Mailler, R. Adams, K. Univ Tulsa Dept Mech Engn 800 S Tucker Dr Tulsa OK 74104 USA Univ Tulsa Tandy Sch Comp Sci 800 S Tucker Dr Tulsa OK 74104 USA

The surface adhesion between c. elegans and the agar plates on which they are commonly grown has yet to be accurately quantified. c. elegans is a scientifically important species of nematode whose simple structure allowed the first mapping of the complete nervous system in a multicellular organism. One of the current topics of research in the c. elegans community is the investigation of neuronal function in locomotion. Models of locomotion are used in these studies to aid in determination of the functions of specific neurons involved in locomotion. The adhesion force plays a critical role in developing these models. This paper presents the experimental determination of the adhesion energy of a representative sample of c. elegans. Adhesion energy was determined by a direct pull-off technique. In this approach, nematodes are anesthetized to prevent movement and secured to a small load cell before an agar plate is slowly brought into contact with the specimen and then removed. The maximum tensile force is then fit to a JKR-type adhesion model, which assumes that the nematode is a cylinder in order to determine the adhesion energy. Repeated adhesions are also investigated to determine the importance of drying on the measured adhesion force. From these experiments, the adhesion energy was found to be W =4.94 +/- 1.19 mJ/m(2). Limited experiments on the rol-6 cuticle mutant found a lower adhesion energy W =2.65 +/- 1.16 mJ/m(2) for these animals.

关键词： c elegans Adhesion Mechanical testing

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Finding an optimal core on a tree network with M/G/c/c state-dependent queues

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MATHEMATIcAL METHODS OF OPERATIONS RESEARcH 2019年第1期89卷 115-142页

作者： Moshtagh, Mehrdad Fathali, Jafar Smith, James MacGregor Mahdavi-Amiri, Nezam Shahrood Univ Technol Fac Math Sci Shahrood Iran Univ Massachusetts Dept Mech & Ind Engn Amherst MA 01003 USA Sharif Univ Technol Fac Math Sci Tehran Iran

We consider the stochastic queue core problem on a tree network. Our aim is to find an optimal path on a tree network subject to the average travel time of particles moving along the tree for service given by a server traversing along the optimal path. We assume that particles originating at a node on a tree network request their demands for service randomly and the server is modeled first by an M/M/1 and then by an M/G/1 queue using the FIFO discipline. We consider that all paths along which the particles travel are modeled with an M/G/c/c state-dependent queue with the particles being independent of each other having demands according to the Poisson distribution. Two algorithms are developed for computing the optimal path on a tree network along with the M/M/1 and the M/G/1 queues. The computational complexity of the algorithms and illustrative numerical results obtained by implementations of the algorithms in MATLAB software environment are given.

关键词： Facility location core of a tree network Stochastic queue core M G c c state-dependent queue Queueing theory

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cyclin c regulates adipogenesis by stimulating transcriptional activity of ccAAT/enhancer-binding protein α

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JOURNAL OF BIOLOGIcAL cHEMISTRY 2017年第21期292卷 8918-8932页

作者： Song, Ziyi Xiaoli, Alus M. Zhang, Quanwei Zhang, Yi Yang, Ellen S. T. Wang, Sven chang, Rui Zhang, Zhengdong D. Yang, Gongshe Strich, Randy Pessin, Jeffrey E. Yang, Fajun Northwest A&F Univ Dept Anim Sci Coll Anim Sci & Technol Lab Anim Fat Deposit & Muscle Dev Yangling 712100 Shaanxi Peoples R China Albert Einstein Coll Med Dept Med Div Endocrinol Bronx NY 10461 USA Albert Einstein Coll Med Diabet Res Ctr Bronx NY 10461 USA Albert Einstein Coll Med Dept Dev & Mol Biol Bronx NY 10461 USA Albert Einstein Coll Med Dept Genet Bronx NY 10461 USA Albert Einstein Coll Med Dept Mol Pharmacol Bronx NY 10461 USA Icahn Sch Med Mt Sinai Dept Genet & Genom Sci New York NY 10029 USA Rowan Univ Sch Osteopath Med Dept Mol Biol Stratford NJ 08055 USA

Brown adipose tissue is important for maintaining energy homeostasis and adaptive thermogenesis in rodents and humans. As disorders arising from dysregulated energy metabolism, such as obesity and metabolic diseases, have increased, so has interest in the molecular mechanisms of adipocyte biology. Using a functional screen, we identified cyclin c (cycc), a conserved subunit of the Mediator complex, as a novel regulator for brown adipocyte formation. siRNA-mediated cycc knockdown (KD) in brown preadipocytes impaired the early transcriptional program of differentiation, and genetic KO of cycc completely blocked the differentiation process. RNA sequencing analyses of cycc-KD revealed a critical role of cycc in activating genes co-regulated by peroxisome proliferator activated receptor gamma (PPAR alpha) and ccAAT/enhancer-binding protein alpha (c/EBP alpha). Overexpression of PPAR gamma(2) or addition of the PPAR gamma ligand rosiglitazone rescued the defects in cycc-KO brown preadipocytes and efficiently activated the PPAR gamma-responsive promoters in both WT and cycc-KO cells, suggesting that cycc is not essential for PPAR gamma transcriptional activity. In contrast, cycc-KO significantly reduced c/EBP alpha-dependent gene expression. Unlike for PPAR gamma, overexpression of c/EBP alpha could not induce c/EBP alpha target gene expression in cycc-KO cells or rescue the cycc-KO defects in brown adipogenesis, suggesting that cycc is essential for c/EBP alpha-mediated gene activation. cycc physically interacted with c/EBP, and this interaction was required for c/EBP alpha transactivation domain activity. consistent with the role of c/EBP alpha in white adipogenesis, cycc-KD also inhibited differentiation of 3T3-L1 cells into white adipocytes. Together, these data indicate that cycc activates adipogenesis in part by stimulating the transcriptional activity of c/EBP alpha.

关键词： adipocyte adipogenesis cell differentiation gene expression transcription coregulator c EBP cyclin c PPAR brown adipocyte Mediator complex

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co3O4/NiO/c composites derived from zeolitic imidazolate frameworks (ZIFs) as high-performance anode materials for Li-ion batteries

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JOURNAL OF SOLID STATE ELEcTROcHEMISTRY 2020年第5期24卷 1133-1142页

作者： Li, Zhitong Zhao, Jian Nie, Jiajin Yao, Shaowei Wang, Jing Feng, Xiaoxin North China Univ Sci & Technol Coll Mat Sci & Engn Tangshan 063210 Peoples R China Key Lab Inorgan Mat Hebei Prov Tangshan 063210 Peoples R China

In this paper, co3O4/NiO/c composites were prepared by in situ co-precipitation and heat treatment with Zn/co-ZIF-derived N-doped porous carbon as carbon matrix. The structure and constituent of co3O4/NiO/c composites were detected by the X-ray diffraction (XRD), scanning electron microscope (SEM), transmission electron microscope (TEM), and other test methods. The result showed that Nico-LDH nanosheets grew evenly on the surface of porous carbon matrix. co3O4/NiO/c composites retained the dodecahedral shape of the carbon matrix. Electrochemical performance was investigated through electrochemical workstation and LAND-cT2001A battery test system. The results showed that the co3O4/NiO/c electrode has a higher initial discharge specific capacity of 1673.0 mA h g(-1) at 0.1 A g(-1), and it could still maintain the discharge specific capacity of 1167.8 mA h g(-1) after 100 cycles. The co3O4/NiO/c showed a high reversible capacity of 812.3 mA h g(-1) after 500 cycles at 0.5 A g(-1). The co3O4/NiO/c electrode exhibited excellent lithium storage performance, which can be attributed to the unique functionalities of the ternary components: NiO and co3O4 can guarantee high specific capacity, while the carbon matrix can improve the conductivity and the stability of the structure. Therefore, co3O4/NiO/c composite was expected to be anode material for lithium storage equipment.

关键词： co3O4 NiO c N-doped porous carbon Anode material Li-ion batteries

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Multi-walled carbon nanotubes induce transgenerational toxicity associated with activation of germline long non-coding RNA linc-7 in c. elegans

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cHEMOSPHERE 2022年 301卷 134687页

作者： Zhao, Yingyue Xu, Ruoran Hua, Xin Rui, Qi Wang, Dayong Nanjing Agr Univ Coll Life Sci Nanjing 210095 Peoples R China Southeast Univ Med Sch Nanjing 210009 Peoples R China

With the increase in application, multi-walled carbon nanotubes (MWcNTs) are potentially bioavailable to environmental organisms. However, the potential transgenerational effect of MWcNTs and underlying mechanisms remains still unclear. Here, we examined transgenerational MWcNT toxicity and the underlying mechanism mediated by germline long non-coding RNAs (lncRNAs) in caenorhabditis elegans. Exposure to 0.1-10 mu g/L MWcNT caused transgenerational toxicity reflected by endpoints of brood size and locomotion behavior. Meanwhile, among germline lncRNAs, expression of 5 lncRNAs were dysregulated by MWcNT exposure. Among these 5 dysregulated lncRNAs, only germline RNAi of linc-7 affected MWcNT toxicity. Increase in germline linc-7 expression was observed transgenerationally, and transgenerational MWcNT toxicity was prevented in linc-7 (RNAi) nematodes. Moreover, germline linc-7 controlled transgenerational MWcNT toxicity by activating downstream DAF-12, a transcriptional factor. Therefore, our data indicated the association between induction of transgenerational MWcNT toxicity and increase in germline linc-7 expression in organisms.

关键词： Multi-walled carbon nanotubes Germline linc-7 Transgenerational toxicity c elegans

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Hepatitis c virus may infect extrahepatic tissues in patients with hepatitis c

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World Journal of Gastroenterology 2000年第6期6卷 805-811页

作者： Fu Ming Yan An Shen chen Fei Hao Xi Ping Zhao chang Hai Gu Li Bin Zhao Dong Liang Yang Lian Jie Hao Department of Infectious Diseases the 161st Central Hospital of Chinese PLAWuhan 430010Hubei ProvinceChina Department of Infectious Diseases Southwest HospitalThird Military Medical UniversityChongqingChina Division of Clinical Immunology Tongji HospitalTongji Medical UniversityWuhanHubei ProvinceChina

AIM To explore the status of extrahepatichepatitis c virus(HcV)infection and replicationin hepatitis c patients,and its potentialimplication in HcV infection and *** By reverse-transcriptase poly-merase chain reaction(RT-PcR),in situhybridization(ISH)and immunohistochemistry,HcV RNA,HcV replicative intermediate(minus-strand of HcV RNA),and HcV antigens weredetected in 38 autopsy extrahepatic tissuespecimens(including 9 kidneys,9 hearts,9pancreas,5 intestines,2 adrenal glands,2spleens,1 lymph node,and 1 gallbladder)from 9hepatitis c patients,respectively;and thestatus of HcV replication in extrahepatic tissueswas *** By RT-PcR,all 9 patients werepositive for HcV RNA in kidney,heart,pancreas,and intestine,but only 6(66.7%)patients were positive for HcV *** RNA and HcV antigens weredetected in kidney,heart,pancreas,intestine,adrenal gland,lymph node,and gallbladder in 5(55.6%)and 6(66.7%)patients by ISH andimmunohistochemistry,*** RNA and HcV antigens were not detected in theseextrahepatic organs in 3(33.3%)patients,although their livers were positive for *** intermediate detected by RT-PcR wasconsistent with HcV RNA and HcV antigensdetected by ISH and immunohistochemistry(Kappa=0.42-0.75).HcV RNA and HcVantigens were detected in myocardial cells,epithelial cells of intestinal gladular,interstitialcells of kidney,epithelial cells of tubules andglomerulus,pancreas acinar cells and epithelialcells of pancreatic duct,epithelial cells ofmucous membrane sinus of gallbladder,cortexand medulla cells in adrenal gland,andmononuclear cells in lymph *** RNA wasalso detected in bile duct epithelial cells,sinusoidal cells,and mononuclear cells in livertissues by *** HcV can infect extrahepatictissues,and many various tissue cells maysupport HcV replication;extrahepatic HcVinfection and replication may be of'concomitantstate'in most of patients with hepatitis *** extrahepatic

关键词： hepatitis c virus hepatitis c antigens in situ hybridization immunohistochemistry RNA polymerase chain reaction antibodies monoclonal digoxigenin

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Normal impact behaviour of c/Sic rigid-felt titanium alloy three-layered plate

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FATIGUE & FRAcTURE OF ENGINEERING MATERIALS & STRUcTURES 2016年第3期39卷 357-371页

作者： chen, L. Yao, X. cen, S. Wang, S. Tsinghua Univ Sch Aerosp Engn Dept Engn Mech Beijing 100084 Peoples R China Tsinghua Univ Sch Aerosp Engn Ctr High Performance Comp Beijing 100084 Peoples R China Natl Univ Def Technol Coll Aerosp & Mat Engn State Key Lab Adv Ceram Fibers & Composites Changsha 410073 Hunan Peoples R China

In this paper, impact damage behaviours of c/Sic rigid-felt titanium alloy three-layered plate under normal impact are investigated. First, low velocity impact experiment of the three-layered plate is performed by means of a drop weight impact apparatus. Second, the finite element model of the three-layered plate is established using a damage constitutive model;also, the influences of the initial kinetic energy (the initial velocity and the mass of the impactor) on stress distributions and damage patterns of the three-layered plate are analysed. Finally, the energy dissipation mechanisms and failure characterizations of the three-layered plate are discussed;also, the agreements of physical variables and damage morphologies between experimental and numerical results validate the reliability of numerical simulation. The results will play an important role in designing and evaluating advanced thermal protection structure.

关键词： c Sic composite damage finite element analysis low-velocity impact multilayered plate thermal protection structure (TPS)

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construction of sandwich-structured c/c-Sic and c/c-Sic-Zrc composites with good mechanical and anti-ablation properties

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JOURNAL OF THE EUROPEAN cERAMIc SOcIETY 2022年第4期42卷 1219-1226页

作者： Zhao, Rida Hu, chenglong Wang, Yuanhong Pang, Shengyang Li, Jian Tang, Sufang cheng, Hui-Ming Chinese Acad Sci Inst Met Res Shenyang 110016 Peoples R China Univ Sci & Technol China Sch Mat Sci & Engn Hefei 230026 Peoples R China China Aerosp Sci & Ind Corp Res Inst 31 Beijing 100074 Peoples R China Chinese Acad Sci Inst Met Res Shenyang Natl Lab Mat Sci Shenyang 110016 Peoples R China

Four kinds of sandwich-structured c/c-Sic and c/c-Sic-Zrc composites with or without a Sic interphase deposited by isothermal chemical vapor infiltration (IcVI), were designed and fabricated by a joint process of electromagnetic coupling chemical vapor infiltration (EcVI) and precursor infiltration and pyrolysis (PIP). The fabricated composites are macroscopically nonhomogeneous materials with low density, high strength and low ablation rate. The interphase and matrix constituents had remarkable effects on the mechanical and ablation properties of these composites. The c/c-Sic composites with an IcVI-Sic interphase exhibited the highest flexural strength of 306.5 MPa. While the c/c-Sic-Zrc composites with the interphase showed the best antiablation performance with low linear and mass ablation rates of 0.37 mu m/s and 0.04 mg/cm2.s, respectively, after the ablation for 500 s under an oxyacetylene flame test at around 2000 degrees c.

关键词： Sandwich-structure c c-Sic-Zrc Flexural property Ablation behavior

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