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Video-Assisted Mediastinoscopic Lymphadenectomy for Staging Non-Small cell Lung cancer

ANNALS OF THORAcIc SURGERY 2016年第4期101卷 1326-1333页

作者： call, Sergi Obiols, carme Rami-Porta, Ramon carlos Trujillo-Reyes, Juan Iglesias, Manuela Saumench, Roser Gonzalez-Pont, Guadalupe Serra-Mitjans, Mireia Belda-Sanchis, Jose Univ Barcelona Hosp Univ Mutua Terrassa Dept Thorac Surg Barcelona Spain CIBERES Lung Canc Grp Barcelona Spain Univ Barcelona Hosp Univ Mutua Terrassa Dept Pathol Barcelona Spain

Background. The aim of this study was to evaluate the results of video-assisted mediastinoscopic lymphadenectomy (VAMLA) for staging of non-small cell lung cancer (NScLc). Methods. This was a prospective observational study of all consecutive VAMLAs performed from January 2010 to April 2015 for staging NScLc. For left lung cancers, extended cervical videomediastinoscopy was added to explore the subaortic and paraaortic nodes. Patients with negative VAMLA results underwent tumor resection and lymphadenectomy of the remaining nodes. Those with N2-3 disease underwent chemoradiation. The rate of unsuspected pathologic (p)N2-3 was analyzed in the global series and in the subgroups of patients according to their nodal status diagnosed by imaging and metabolic techniques. Results. One hundred sixty VAMLAs were performed for staging NScLc (138 tumors were clinical (c)N0-1 based on imaging techniques). The rate of unsuspected N2-3 disease was 18% for the whole series: 40.7% for cNi, 22.2% for cNO and tumor size greater than or equal to 3 cm, and 6.4% for cNO and tumor size less than 3 cm. Staging values were sensitivity, 0.96 (95% confidence interval [cI], 0.81-99.3);specificity, 1 (95% cI, 0.97-1);positive predictive value, 1 (95% cI, 0.87-1);negative predictive value, 0.99 (95% cI, 0.95-0.99);and diagnostic accuracy, 0.99 (95% cI, 0.96-0.99). The complication rate was 5.9%. conclusions. VAMLA is a feasible and highly accurate technique. The high rate of unsuspected mediastinal node disease diagnosed by VAMLA in patients with cN1 or cNO disease and tumor size larger than 3 cm suggests that preresection lymphadenectomies should be included in the current staging algorithms. (c) 2016 by The Society of Thoracic Surgeons

关键词： c clinical cI confidence interval cT computed tomography D lco diffusing capacity of the lung for carbon monoxide ESTS European Society of Thoracic Surgeons EBUS-FNA endobronchial ultrasonographic fine-needle aspiration EUS-FNA esophageal ultrasonographic fine-needle aspiration FEV 1 forced expiratory volume in the first second of expiration IASLc International Association for the Study of Lung cancer Lc lung cancer NScLc non-small cell lung cancer p pathologic PET positron emission tomography ScLc small cell lung cancer TEMLA transcervical extended mediastinal lymphadenectomy TNM classification tumor, node, and metastasis classification VAMLA video-assisted mediastinoscopic lymphadenectomy

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铝合金锻造表面缺陷分析

铝合金锻造表面缺陷分析

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2021年中国铝加工产业年度大会暨中国(湖州)铝加工绿色智造高峰论坛

作者：李其荣浦俭英储剑月陈仁春李德松曹辉吴桂兰亚太轻合金南通科技有限公司

铝合金圆棒经过锻造后发现表面有金属凸起,对该缺陷进行了宏观和显微组织的观察及扫描电镜和EDS的分析。研究结果表明:该金属凸起的截面以看到疑似裂纹的线条,线条近似平行于锻造外形轮廓;缺陷边缘较为光滑、无撕裂状痕迹,未见任何塑形... 详细信息

铝合金圆棒经过锻造后发现表面有金属凸起,对该缺陷进行了宏观和显微组织的观察及扫描电镜和EDS的分析。研究结果表明:该金属凸起的截面以看到疑似裂纹的线条,线条近似平行于锻造外形轮廓;缺陷边缘较为光滑、无撕裂状痕迹,未见任何塑形变形痕迹;缺陷界面上发现一个多面体结构的颗粒状嵌入物,直径在2-3μm;颗粒物的EDS成分里的c含量高达97%,推断出该颗为脱模剂的掉落物。

关键词：铝合金颗粒 c

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Growth of single-walled carbon nanotube at a low temperature by alcohol catalytic chemical vapor deposition using Ru catalysts – RETRAcTION

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MRS Advances 2018年第1-2期3卷 129-129页

作者： Takayuki Fujii Takuya Okada Takahiro Saida Shigeya Naritsuka Takahiro Maruyama Department of Materials Science and Engineering Meijo University Tempaku Nagoya Japan Department of Applied Chemistry Meijo University Tempaku Nagoya Japan

Growth of single-walled carbon nanotube (SWcNT) was achieved by an alcohol catalytic chemical vapor deposition (cVD) mechanism that was conducted in a high vacuum using Ru catalysts. By optimizing the ethanol pressure, SWcNTs can grow in a wide range of temperature between 500 °c and 900 °c. Both the yield and crystalline quality of SWcNTs reached their maxima at 700 °c. Significantly, the SWcNT growth was achieved even at 450 °c, which was much lower than the growth temperatures that were required for SWcNT growth using Ru catalysts previously. Raman measurements exhibited that the diameter distribution of the SWcNTs that were grown at 450 °c was quite narrow and (11, 4) nanotubes were dominant. The observations of transmission electron microscope (TEM) suggested that the size of the Ru particles were larger than the diameter of SWcNT. Such a relation was similar to the relation observed in the growth of SWcNTs using Pt catalysts.

关键词： chemical vapor deposition (cVD) (chemical reaction) c nanostructure

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Degradation Mechanism Induced by Psoriasis in Human Fingernails: A Different Approach

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JOURNAL OF INVESTIGATIVE DERMATOLOGY 2016年第1期136卷 311-313页

作者： coroaba, Adina Pinteala, Tudor chiriac, Anca chiriac, Anca E. Simionescu, Bogdan c. Pinteala, Mariana Romanian Acad Petru Poni Inst Macromol Chem Ctr Adv Res Bionanoconjugates & Biopolymers Iasi Romania Grigore T Popa Univ Med & Pharm East European Network Excellence Res & Dev Chron Iasi Romania Grigore T Popa Univ Med & Pharm Dept Gen Med Iasi Romania Nicolina Med Ctr Dept Dermatol Iasi Romania Apollonia Univ Iasi Dept Dermatophysiol Iasi Romania

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Dehydroascorbic acid for the treatment of acute ischemic stroke

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MEDIcAL HYPOTHESES 2016年 89卷 32-36页

作者： Spector, Reynold Robert Wood Johnson Med Sch Dept Med Piscataway NJ 08554 USA

In animal models of acute ischemic stroke, intravenous dehydroascorbic acid (DHAA), unlike ascorbic acid (AA), readily enters brain and is converted in both normal and ischemic brain into protective ascorbic acid. When given parenterally DHAA minimizes infarct volume and facilitates functional recovery. I hypothesize the same effect will occur in humans with acute ischemic stroke. Efficacy in reducing infarct volume is demonstrable in mice and rats even when DHAA is infused three hours after the experimental infarct. Moreover, there is fivefold mechanistic rational for DHA beside excellent pharmacokinetics and rapid penetration of brain and conversion to protective AA: (1) in ischemic brain, there is a precipitous decline in AA which can be reversed by intravenous DHAA;(2) after reduction of DHAA to AA in both normal and ischemic brain, AA can reduce oxidized vitamin E and glutathione, other protectors of brain against damaging reactive oxygen species which build up in ischemic brain;(3) AA itself can protect brain against damaging reactive oxygen species;(4) AA is an essential cofactor for several enzymes in brain including ten-eleven translocase-2 which upregulates production of protective molecules like brain derived neurotrophic factor;and (5) DHAA after conversion to AA prevents both lipid oxidation and presumably oxidation of other labile substances (e.g., dopamine) in ischemic brain. In terms of safety, based on all available animal information, DHAA is safe in the proposed dosing regimen. For human clinical trials, the methodology for conducting the proposed animal safety, clinical pharmacology and phase II efficacy studies is straightforward. Finally, if DHAA preserved brain substance and function in humans, it could be employed in pre-hospital stroke patients. (c) 2016 Elsevier Ltd. All rights reserved.

关键词： AbbreviationsAA ascorbic acid BBB blood-brain barrier BDNF brain-derived neurotrophic factor BP blood pressure c cytosine cSF cerebrospinal fluid DHAA dehydroascorbic acid GLP Good Laboratory Practices GSH glutathione GSSH oxidized glutathione iNOS inducible nitric oxide synthetase McA middle cerebral artery OHMec hydroxymethylcytosine ROS reactive oxygen species SVcT sodium-dependent vitamin c transporter TET ten-eleven translocation enzymes tPA tissue plasminogen activator

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3D porous graphene synthesised using different hydrothermal treatment times for the removal of lead ions from an aqueous solution

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MIcRO & NANO LETTERS 2017年第5期12卷 308-311页

作者： Zhou, Fang Yu, Jingang Jiang, Xinyu Cent S Univ Sch Chem & Chem Engn Changsha 410083 Hunan Peoples R China

Three-dimensional porous graphene (3D PG) synthesised using different hydrothermal treatment times was obtained by an environmentally friendly freeze-drying method. The as-prepared 3D PG was characterised by Raman spectroscopy, scanning electron microscopy, thermogravimetric analysis and Brunauer-Emmett-Teller measurement. The results showed that 3D porous graphene synthesised over a shorter hydrothermal treatment time had more graphitic structural defects and oxygen-containing functional groups. Adsorption experiments were conducted to investigate the influence of hydrothermal treatment time on the removal of lead ions. In addition, it was revealed that shorter hydrothermal treatment times led to higher adsorption capacities for the 3D PG. This study provides the first evidence of the hydrothermal treatment time of 3D PG playing a critical role in the removal of metal ions from an aqueous solution.

关键词： lead porous materials graphene drying Raman spectra scanning electron microscopy thermal analysis adsorption 3D porous graphene hydrothermal treatment times lead ion removal aqueous solution environmentally friendly freeze-drying method Raman spectroscopy scanning electron microscopy thermogravimetric analysis Brunauer-Emmett-Teller measurement graphitic structural defects oxygen-containing functional groups adsorption c Pb

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Enhancing the visible light absorption of titania nanoparticles by S and c doping in a single-step process

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APPLIED SURFAcE ScIENcE 2014年 302卷 11-18页

作者： Scarisoreanu, M. Morjan, I. Alexandrescu, R. Fleaca, c. T. Badoi, A. Dutu, E. Niculescu, A. -M. Luculescu, c. Vasile, E. Wang, J. Bouhadoun, S. Herlin-Boime, N. Natl Inst Lasers Plasma & Radiat Phys Bucharest 077125 Romania Metav Res & Dev Bucharest 020011 Romania CEA Saclay CNRS URA 2453 IRAMIS SPAMLFP F-91191 Gif Sur Yvettes France

We report the synthesis of carbon coated and sulfur doped titania nanoparticles using a continuous, single-step laser pyrolysis technique. We employed air as oxidant and c2H4 as laser energy transfer agent (sensitizer)/carbon donor, both carrying the Ticl4 vapors as a titania precursor. The volatile (cH3)(2)S-2 was used to introduce sulfur as dopant in the nanopowders. The incorporation of c and S atoms in nanopowders with anatase dominant phase and with average particle diameter between 18 and 25 nm was performed through the addition of S-2(cH3)(2) and c2H4 to the reactive precursor mixtures. The samples were characterized by: EDX, XRD, TEM, XPS and UV-Vis spectroscopy. By the introduction of the sulfur precursor, the anatase-to-rutile ratio within the resulted TiO2-based nanoparticles decreased, as well as their bandgap energy values which are also lower than those of commercial TiO2 Degussa P25. (c) 2014 Elsevier B.V. All rights reserved.

关键词： Laser pyrolysis Nanoparticles c S-modified TiO2 Band gap energy UV-Vis spectroscopy

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RETRAcTION: Growth of single-walled carbon nanotube at a low temperature by alcohol catalytic chemical vapor deposition using Ru catalysts (Retraction Article) (Retraction of Vol 3, Pg E 1, 2018)

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MRS ADVANcES 2018年第1-2期3卷 E1-E7页

作者： Fujii, Takayuki Okada, Takuya Saida, Takahiro Naritsuka, Shigeya Maruyama, Takahiro Meijo Univ Dept Mat Sci & Engn Tempa Ku 1-501 Shiogamoguchi Nagoya Aichi Japan Meijo Univ Dept Appl Chem Tempa Ku 1-501 Shiogamoguchi Nagoya Aichi Japan

Growth of single-walled carbon nanotube (SWcNT) was achieved by an alcohol catalytic chemical vapor deposition (cVD) mechanism that was conducted in a high vacuum using Ru catalysts. By optimizing the ethanol pressure, SWcNTs can grow in a wide range of temperature between 500 degrees c and 900 degrees c. Both the yield and crystalline quality of SWcNTs reached their maxima at 700 degrees c. Significantly, the SWcNT growth was achieved even at 450 degrees c, which was much lower than the growth temperatures that were required for SWcNT growth using Ru catalysts previously. Raman measurements exhibited that the diameter distribution of the SWcNTs that were grown at 450 degrees c was quite narrow and (11, 4) nanotubes were dominant. The observations of transmission electron microscope (TEM) suggested that the size of the Ru particles were larger than the diameter of SWcNT. Such a relation was similar to the relation observed in the growth of SWcNTs using Pt catalysts.

关键词： chemical vapor distribution (cVD) (chemical reaction) c nanostructure

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Improving code quality in ROS packages using a temporal extension of first-order logic

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Encyclopedia with Semantic computing and Robotic Intelligence 2018年第1期2卷

作者： David come Julien Brunel David Doose DTIM ONERA 2 Avenue Edouard Belin 31400 Toulouse France

Robots are given more and more challenging tasks in domains such as transport and delivery, farming or health. Software is a key component for robots, and Robot Operating System (ROS) is a popular open-source middleware for writing robotics applications. code quality matters a lot because a poorly written software is much more likely to contain bugs and will be harder to maintain over time. Within a code base, finding faulty patterns takes a lot of time and money. We propose a framework to search automatically user-provided faulty code patterns. This framework is based on F O + + , a temporal extension of first-order logic, and Pangolin, a verification engine for c + + programs. We formalized with F O + + five faulty patterns related to ROS and embedded systems. We analyzed with Pangolin 25 ROS packages looking for occurrences of these patterns and found a total of 218 defects. To prevent the faulty patterns from arising in new ROS packages, we propose a design pattern, and we show how Pangolin can be used to enforce it.

关键词： ROS c + + temporal logic formal methods code query

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Graphene Oxide Based Fruit Ripeness Sensing e-Nose

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Materials Today: Proceedings 2018年第3期5卷 9866-9870页

作者： Mintu Mallick Syed Minhaz Hossain Jayoti Das Department of Physics Jadavpur University Kolkata 700032 India Department of Physics Indian institute of Engineering Science and Technology Shibpur Howrah 711103 India

Graphene oxide (GO) is prepared by chemical route via Hummer’s method from pure graphite powder and characterized structurally by XRD and FESEM analysis. A conductive type pellet sensor has been fabricated and the response of this GO based gas sensor towards ethylene gas emitted by fruits has been studied in a closed chamber in presence of unripe and ripe fruits at room temperature. The results show that, the conductivity of the developed sensor changes depending upon the amount of ethylene gas emitted from the fruit kept in the sensing chamber, and thus our sensor can clearly differentiate between an unripe and a ripe fruit.

关键词： Graphene oxide c 2 H 4 gas sensor Fruit ripeness sensor

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