Hollow tubular structure TiO2/c photocatalyst was prepared by carbonization at 400celcius with cotton fabric as initial carrier and tetrabutyltitanate as precursor. The structure of the samples was characterized by SE...
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Hollow tubular structure TiO2/c photocatalyst was prepared by carbonization at 400celcius with cotton fabric as initial carrier and tetrabutyltitanate as precursor. The structure of the samples was characterized by SEM and XRD. The results show that anatase crystal TiO2 with good crystallization is formed, TiO2 was uniformly distributed on the surface of the hollow tubular carbon material. The photocatalytic degradation performance was measured by using the methylene blue as the target dyes. When the dosage of TiO2/c was 1.7 g/L, the degradation rate of methylene blue solution was high up to 97.5%. The effective degradation of dyes was realized by using the strong adsorption property of hollow carbon materials and the high photocatalytic activity of anatase titanium dioxide. Due to the repeated adsorption of carbon materials to dyes and the continuous degradation of titanium dioxide to dyes, TiO2/c photocatalyst could be regenerated in situ.
Abrus mollis is commonly used as a traditional chinese medicine for the treatment of liver diseases due to its hepatoprotection and anti-inflammation, but the absorption properties of its main bioactive ingredients re...
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Abrus mollis is commonly used as a traditional chinese medicine for the treatment of liver diseases due to its hepatoprotection and anti-inflammation, but the absorption properties of its main bioactive ingredients remain unclear. Our previous studies verified that the flavonoid c -glycosides, including vicenin-2 ( 1 ), isoschaftoside ( 2 ), and schaftoside ( 3 ), were the major active components in A. mollis for hepatic protection against nonalcoholic fatty liver disease, hepatitis, and hepatic fibrosis. This study investigated the bioaccessibility and transport mechanisms of total flavonoid c -glycoside, as well as vicenin-2 ( 1 ), isoschaftoside ( 2 ), and schaftoside ( 3 ), in A. mollis by simulated digestion and use of the caco-2 cell model. Moreover, this study attempted to verify their absorption properties by in situ gastrointestinal perfusion in rats. Total flavonoid c -glycoside and 1, 2 , and 3 exhibited similar bioaccessibility of 84.58%, 85.13%, 83.05%, and 81.65% respectively after simulated digestion. The transport of total flavonoid c -glycoside in the caco-2 cell model increased with the concentration, and the transport showed saturation characteristics with the time and concentration of total flavonoid c -glycoside to a certain degree. The Papp values of total flavonoid c -glycoside and the 3 flavonoid c -glycosides were significantly improved by verapamil, probenecid, and EDTA-Na (2) . Their absorption properties in the gastrointestinal tract were consistent with that found in caco-2 cells, and superior absorption rates were observed in the duodenum and jejunum. The absorption pattern of total flavonoid c -glycoside may involve multiple transport pathways, including active transport, passive diffusion, and the paracellular pathway. TFc was actively pumped out by P-glycoprotein and multidrug resistance-associated protein. These results revealed that the bioaccessibility and intestinal absorption characteristic of total flavonoid c -glycoside were c
Rust is a relatively new programming language that targets efficient and safe systems-level applications. It includes a sophisticated type system that allows for provable memory- and thread-safety, and is explicitly d...
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Rust is a relatively new programming language that targets efficient and safe systems-level applications. It includes a sophisticated type system that allows for provable memory- and thread-safety, and is explicitly designed to take the place of unsafe languages such as c and c++ in the coding ecosystem. There is a large existing c and c++ codebase (many of which have been affected by bugs and security vulnerabilities due to unsafety) that would benefit from being rewritten in Rust to remove an entire class of potential bugs. However, porting these applications to Rust manually is a daunting task. In this paper we investigate the problem of automatically translating c programs into safer Rust programs- that is, Rust programs that improve on the safety guarantees of the original c programs. We conduct an in-depth study into the underlying causes of unsafety in translated programs and the relative impact of fixing each cause. We also describe a novel technique for automatically removing a particular cause of unsafety and evaluate its effectiveness and impact. This paper presents the first empirical study of unsafety in translated Rust programs (as opposed to programs originally written in Rust) and also the first technique for automatically removing causes of unsafety in translated Rust programs.
Mn-based aqueous zinc ion batteries (AZIBs) are promising energy storage devices due to its low cost and high performance. However, Jahn-Teller effect of discharge process and Mn2+ dissolution restricts its practical ...
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Mn-based aqueous zinc ion batteries (AZIBs) are promising energy storage devices due to its low cost and high performance. However, Jahn-Teller effect of discharge process and Mn2+ dissolution restricts its practical application. Herein, we report a Zn/co co-doped MnO/c (Znco-MnO/c) derived from metal organic framework (MOF) with high specificcapacity and cyclic stability, which benefits from the synergistic effect of Zn/co ions. The doping of Zn ions improves the low specificcapacity of MnO in the initial activation process, and co ions can effectively inhibit the Jahn-Teller effect of discharge products and enhance the structural stability. The syner-gistic effect of Zn/co co-doped further enhances the conductivity and ion diffusion rate of MnO. In addition, the interface protection layer of the zinc anode is constructed by Ti3c2cl2 (Ti3c2@Zn), which can effectively inhibit dendrite growth and further improve the cycle life of AZIBs. Specifically, the assembled Znco-MnO/c// Ti3c2@Zn full battery has a specificcapacity of 428.9 mAh center dot g- 1 at 0.1 A center dot g-1. With 3000 cycles at 3.0 A center dot g-1, the capacity retention rate is 98.7 %. This work emphasizes the significance of co-doped on the electronic structure of MOF derived MnO/c for efficient AZIBs.
Ageing is a biological process guided by genetic and environmental factors that ultimately lead to adverse outcomes for organismal lifespan and healthspan. Determination of molecular pathways that are affected with ag...
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Ageing is a biological process guided by genetic and environmental factors that ultimately lead to adverse outcomes for organismal lifespan and healthspan. Determination of molecular pathways that are affected with age and increase disease susceptibility is crucial. The gene expression profile of the ideal ageing model, namely the nematode caenorhabditis elegans mapped with the microarray technology initially led to the identification of age-dependent gene expression alterations that characterize the nematode's ageing process. The list of differentially expressed genes was then utilized to construct a network of molecular interactions with their first neighbors/interactors using the interactions listed in the WormBase database. The subsequent network analysis resulted in the unbiased selection of 110 candidate genes, among which well-known ageing regulators appeared. More importantly, our approach revealed candidates that have never been linked to ageing before, thus suggesting promising potential targets/ageing regulators.
The hybridization experiments have been made between crassostrea ariakensis and c. gigas several times. However, it is difficult to obtain a large number of hybrid offspring, which becomes the bottleneck of subsequent...
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The hybridization experiments have been made between crassostrea ariakensis and c. gigas several times. However, it is difficult to obtain a large number of hybrid offspring, which becomes the bottleneck of subsequent cross-breeding. To explore whether the production of hybrid larvae is affected by salinity, we investigated the effects of salinity (16, 20, 24, 28 and 32 psu) on the early activities of artificial hybridization between c. ariakensis and c. gigas at 23-24 degrees c. In this study, the results showed that during artificial insemination, the appropriate salinity of high-quality gametes in c. ariakensis and c. gigas was 20-32 psu and 24-32 psu respectively. Besides, the fertilization rate of AG (c. ariakensis female x c. gigas male) and GA (c. gigas female x c. ariakensis male) at 24-28 psu was significantly (p < .05) higher than that at 16-20 psu. For incubation, the optimal salinity of embryo incubation was 28 psu, under which all embryos of AG and GA can develop rapidly to the D-larvae and yielded a high hatching rate. During larval rearing, the larval shell height and survival rate of AG were of no significant difference (p > .05) at all salinities, and the optimum salinity for larval growth and survival of GA was 24-28 psu. These findings can contribute to the increase in the hybrid progeny yield, which can serve as the new resource for genetic improvement of oyster germplasm.
a-Synuclein is a major component of Lewy bodies and Lewy neuritis which are hallmarks of Parkinson's disease, and is known to propagate from cell-to-cell in a prion-like manner. However, the exact mechanism of a-s...
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a-Synuclein is a major component of Lewy bodies and Lewy neuritis which are hallmarks of Parkinson's disease, and is known to propagate from cell-to-cell in a prion-like manner. However, the exact mechanism of a-synuclein propagation in cells remains unclear. Despite the increasing number of studies and models of a-synuclein propagation, there is no direct evidence demonstrating whether the propagation is trans-synaptic or synapticconnection-independent, what the direction of propagation is, and what the regulators of a-synuclein propagation are. In this study, we generated a caenorhabditis elegans model that can help monitoring the neuron-to-neuron propagation of a-synuclein using BiFc system. Using this model, we demonstrated that a-synuclein was propagated into neurons in both anterograde and retrograde manners, with retrograde propagation being dominant. Interestingly, we also found that endophilin, which is a protein required for classical clathrin-mediated endocytic machinery, was not involved in this retrograde propagation. Furthermore, we demonstrated that a-synuclein inhibits neuronal activity through voltage-gated calcium channels. Our findings suggest a possible mechanism for a-synuclein propagation via synapses through a novel uptake pathway.
The thermal analysis method for unidirectional fiber-reinforced c/Siccomposites (c/Sic-UFRc) in air oxidizing environment below 1000 degrees c is developed, including a mathematical theoretical model and a finite ele...
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The thermal analysis method for unidirectional fiber-reinforced c/Siccomposites (c/Sic-UFRc) in air oxidizing environment below 1000 degrees c is developed, including a mathematical theoretical model and a finite element model. The mathematical model (MM) is established by combining the thermal resistance network method and the oxidation kinetics theory. The influence of oxidation characteristics on c/Sic-UFRc axial thermal conduc-tivity is firstly introduced into MM, which provides a reference for the theoretical calculation method of c/Sic-UFRc axial thermal conductivity under oxidation conditions. The finite element model (FEM) is constructed on the representative volume element (RVE) of c/Sic-UFRc and the numerical heat transfer method. The FEM numerically simulated the microstructure in the oxidation process and firstly be applied to study the effects of oxidation on the micro temperature field and heat transfer of c/Sic-UFRc. Through the mutual confirmation of MM and FEM, the prediction of thermal conductivity of cMc in air oxidation environment is verified. The effects of oxidation time, oxidation temperature and random distribution of initial cracks are investigated to reveal their influences on the heat transfer behavior of c/Sic-UFRc.
Engineering high-performance inexpensive TaN-modified Pd-based nanostructures for alkaline methanol oxidation reaction(MOR) has attracted extensive attention, yet the related enhancement mechanism of TaN for MOR remai...
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Engineering high-performance inexpensive TaN-modified Pd-based nanostructures for alkaline methanol oxidation reaction(MOR) has attracted extensive attention, yet the related enhancement mechanism of TaN for MOR remains lacked. The core-shell like Pd3Ni1-TaN/ccatalyst decorated with Ni(OH)2/NiOOH that contains highly dispersed Ni sites and nitrogen defects has been fabricated for the first time. The unsaturated coordination environment and core-shell like morphology of Pd3Ni1-TaN/c bring fruitful active sites and a down-shifted Dband center, making it a highly-efficient electrocatalyst for alkaline MOR (17.3-fold that of commercial Pd/c). Besides the electronic effects and surface defect sites of Pd3Ni1-TaN/c, TaN also helps MOR proceed via HcOOad pathway (non-cO) accompanied by enhanced OH adsorption induced by the addition of Ni. DFT(Density Functional Theory) calculations also further confirm the energy barrier of the formation of HcOOad intermediate and desorption energy of cO on Pd3Ni1-TaN/c are reduced. The introduction of Ni species and nitrogen vacancies enhances the cO tolerance evidently.
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