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18800 条 记 录,以下是4741-4750 订阅
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PET-Liganden für die Diagnostik der Alzheimer-Demenz: Amyloid und Tau
Der Nuklearmediziner
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Der Nuklearmediziner 2018年 第4期41卷 310-316页
作者: christoph Solbach Marianne Patt Klinik für Nuklearmedizin Universitätsklinikum Ulm Ulm Klinik und Poliklinik für Nuklearmedizin Universitätsklinikum Leipzig Leipzig
Over the last 15 years diagnostic imaging of amyloid and tau deposits with PET has gained increasing importance especially in the context of diagnosis of dementia such as Alzheimer’s disease. First radiotracers that ... 详细信息
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comparative Study of Discrete component Realizations of Fractional-Order capacitor and Inductor Active Emulators
Comparative Study of Discrete Component Realizations of Frac...
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作者: Tsirimokou, Georgia Brno University of Technology
Due to the absence of commercially available fractional-order capacitors and inductors, their implementation can be performed using fractional-order differentiators and integrators, respectively, combined with a volta... 详细信息
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Synthetic Ligands of cannabinoid Receptors Affect Dauer Formation in the Nematode caenorhabditis elegans
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G3-GENES GENOMES GENETIcS 2016年 第6期6卷 1695-1705页
作者: Rodrigues, Pedro Reis Kaul, Tiffany K. Ho, Jo-Hao Lucanic, Mark Burkewitz, Kristopher Mair, William B. Held, Jason M. Bohn, Laura M. Gill, Matthew S. Scripps Res Inst Dept Metab & Aging Jupiter FL 33458 USA Scripps Res Inst Dept Mol Therapeut Jupiter FL 33458 USA Buck Inst Res Aging Novato CA 94945 USA Harvard Univ Sch Publ Hlth Dept Genet & Complex Dis 665 Huntington Ave Boston MA 02115 USA Washington Univ Sch Med Div Oncol St Louis MO 63110 USA Washington Univ Sch Med Dept Anesthesiol St Louis MO 63110 USA
Under adverse environmental conditions the nematode caenorhabditis elegans can enter an alternate developmental stage called the dauer larva. To identify lipophilic signaling molecules that influence this process, we ... 详细信息
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cascket: A Binary Protocol based c client-Driver for Apache cassandra
Cascket: A Binary Protocol based C Client-Driver for Apache ...
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International conference on Advances in computing, communications and Informatics IcAccI
作者: Karpate, Sarang Joshi, Abhishek Dosani, Javed Abraham, Jibi Coll Engn Pune COEP Dept Comp Engn & Informat Technol Pune Maharashtra India
Few can deny the diverse applications of NoSQL Database technology today. The last decade has witnessed an exponential rise in not only data generation but also in the manipulation and management of the same. NoSQL Te... 详细信息
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Proteins that mediate protein aggregation and cytotoxicity distinguish Alzheimer's hippocampus from normal controls
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AGING cELL 2016年 第5期15卷 924-939页
作者: Ayyadevara, Srinivas Balasubramaniam, Meenakshisundaram Parcon, Paul A. Barger, Steven W. Griffin, W. Sue T. Alla, Ramani Tackett, Alan J. Mackintosh, Samuel G. Petricoin, Emanuel Zhou, Weidong Reis, Robert J. Shmookler Cent Arkansas Vet Healthcare Serv McClellan Vet Med Ctr Little Rock AR 72205 USA Univ Arkansas Med Sci Dept Geriatr Little Rock AR 72205 USA Univ Arkansas Med Sci BioInformat Program Little Rock AR 72205 USA Univ Arkansas Little Rock AR 72205 USA Univ Arkansas Med Sci Dept Biochem & Mol Biol Little Rock AR 72205 USA George Mason Univ Ctr Appl Prote & Mol Med Manassas VA 20110 USA
Neurodegenerative diseases are distinguished by characteristic protein aggregates initiated by disease-specific seed' proteins;however, roles of other co-aggregated proteins remain largely unexplored. compact hipp... 详细信息
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Etiology of chronic liver diseases in the Northwest of Italy, 1998 through 2014
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World Journal of Gastroenterology 2016年 第36期22卷 8187-8193页
作者: Giorgio Maria Saracco Andrea Evangelista Sharmila Fagoonee Giovannino ciccone Elisabetta Bugianesi Gian Paolo caviglia Maria Lorena Abate Mario Rizzetto Rinaldo Pellicano Antonina Smedile Department of Oncology University of Turin10123 Turin Italy Unit of Cancer Epidemiology (CPO Piemonte) University of Turin10123 Turin Italy Institute for Biostructures and Bioimages-CNR c/o Molecular Biotechnology Center University of Turin10126 Turin Italy Department of Medical Sciences University of Turin10123 Turin Italy Unit of Gastroenterology Molinette Hospital10123 Turin Italy
AIM To assess the etiology of chronic liver diseases(cLD) from 1998 to 2014 at the outpatient clinic of Gastroenterology of the main hospital in Northwest of Italy among those dedicated to *** A random sample of chart... 详细信息
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硼替佐米在溃疡性结肠炎中治疗作用的实验研究
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胃肠病学 2017年 第7期22卷 402-406页
作者: 胡丽红 李晴 曲波 哈尔滨医科大学附属第二医院消化内科 150086
背景:传统药物对溃疡性结肠炎(Uc)的疗效不尽人意,基于Uc发病机制的药物研发成为Uc研究的热点课题。近年研究表明,核因子-κB(NF-κB)激活在Uc免疫和炎症反应的调节中发挥关键作用。目的:探讨蛋白酶体抑制剂硼替佐米通过抑制NF-κB活化... 详细信息
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comparative mRNA analysis of behavioral and genetic mouse models of aggression
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AMERIcAN JOURNAL OF MEDIcAL GENETIcS PART B-NEUROPSYcHIATRIc GENETIcS 2016年 第3期171卷 427-436页
作者: Malki, Karim Tosto, Maria G. Pain, Oliver Sluyter, Frans Mineur, Yann S. crusio, Wim E. de Boer, Sietse Sandnabba, Kenneth N. Kesserwani, Jad Robinson, Edward Schalkwyk, Leonard c. Asherson, Philip Kings Coll London MRC Social Genet & Dev Psychiat Ctr Inst Psychiat London WC2R 2LS England Tomsk State Univ Lab Cognit Invest & Behav Genet Tomsk 634050 Russia Univ London Birkbeck Ctr Brain & Cognit Dev London England London Sch Hyg & Trop Med Dept Noncommunicable Dis Epidemiol London WC1 England Yale Univ Sch Med Dept Psychiat New Haven CT USA Univ Bordeaux Aquitaine Inst Cognit & Integrat Neurosci Bordeaux France CNRS Aquitaine Inst Cognit & Integrat Neurosci Bordeaux France Univ Groningen Groningen Inst Evolutionary LifeSci GELIFES Groningen Netherlands Abo Akad Univ Fac Arts Psychol & Theol Turku Finland Univ Essex Sch Biol Sci Colchester CO4 3SQ Essex England
Mouse models of aggression have traditionally compared strains, most notably BALB/cJ and c57BL/6. However, these strains were not designed to study aggression despite differences in aggression-related traits and disti... 详细信息
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Impact of micro-environmental changes on respiratory tract infections with intracellular bacteria
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FEBS LETTERS 2016年 第21期590卷 3887-3904页
作者: Shima, Kensuke coopmeiners, Jonas Graspeuntner, Simon Dalhoff, Klaus Rupp, Jan Univ Lubeck Dept Infect Dis & Microbiol Ratzeburger Allee 160 D-23538 Lubeck Germany Univ Hosp Schleswig Holstein Med Clin 3 Campus Lubeck Lubeck Germany
community-acquired pneumonia is caused by intra- and extracellular bacteria, with some of these bacteria also being linked to the pathogenesis of chronic lung diseases, including asthma and chronic obstructive pulmona... 详细信息
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Identification and characterization of LIN-2(cASK) as a Regulator of Kinesin-3 UNc-104(KIF1A) Motility and clustering in Neurons
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TRAFFIc 2016年 第8期17卷 891-907页
作者: Wu, Gong-Her Shanmugam, Muniesh Muthaiyan Bhan, Prerana Huang, Yu-Hsin Wagner, Oliver Ingvar Natl Tsing Hua Univ Inst Mol & Cellular Biol Hsinchu 30013 Taiwan Natl Tsing Hua Univ Dept Life Sci Hsinchu 30013 Taiwan
Kinesin-3 UNc-104(KIF1A) is the major axonal transporter of synaptic vesicles. Employing yeast two-hybrid and co-immunoprecipitation (co-IP) assays, we characterized a LIN-2(cASK) binding site overlapping with that of... 详细信息
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