The nanowire-shaped α-MoO 3 and various metal-doped (W, Nb and Ta) α-MoO 3 was synthesized by hydrothermal route. The synthesized metal oxides were converted into corresponding carbides by carburization method using...
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The nanowire-shaped α-MoO 3 and various metal-doped (W, Nb and Ta) α-MoO 3 was synthesized by hydrothermal route. The synthesized metal oxides were converted into corresponding carbides by carburization method using urea as carbon source. The synthesized carbides were characterized by X-ray diffraction (XRD) and field-emission scanning electron microscopy (FE-SEM) and the electrocatalytic activity for triiodide reduction was studied by cyclic voltammetry. The order of electrocatalytic activity of the synthesized materials are, W-α-Mo 2 c > α-Mo 2 c > Ta-α-Mo 2 c > Nb-α-Mo 2 c. The dye-sensitized solar cell fabricated with W-α-Mo 2 ccounter electrode found to show the better power conversion efficiency (2.53± 0.02%) than pure α-Mo 2 c, Nb and Ta-doped α-Mo 2 c. This study indicates that the W-doped α-Mo 2 c is a potential electrocatalyst for the applications in cost-effective dye-sensitized solar cells.
目的：回顾性分析 Tile c 型骨盆骨折患者死亡相关的危险因素。方法2010年1月至2014年12月我院收治的 Tile c 型骨盆骨折患者139例,收集资料包括术前一般情况、伤后就诊时间、休克指数、各类创伤评分、最低氧合指数、伤后6 h 乳酸清除率...
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目的：回顾性分析 Tile c 型骨盆骨折患者死亡相关的危险因素。方法2010年1月至2014年12月我院收治的 Tile c 型骨盆骨折患者139例,收集资料包括术前一般情况、伤后就诊时间、休克指数、各类创伤评分、最低氧合指数、伤后6 h 乳酸清除率等,采用多因素 Logistic 回归分析死亡相关危险因素。结果入院后死亡41例（29.5%）,其中入院后48 h 内死亡36例（25.9%）。多因素回归分析显示,休克指数＆gt;2（OR=2.591,95%cI 1.041~4.216）、损伤严重程度评分（ISS）≥25分（OR=47.96,95%cI 15.89~147.23）、改良创伤评分（RTS）≤8分（OR=6.917,95%cI 1.147-13.862）、格拉斯哥昏迷评分（GcS）〈9分（OR=4.172,95%cI 2.962~6.268）、最低氧合指数〈200（OR=117.016,95%cI 51.011~176.032）、伤后6 h 乳酸清除率〈10%（OR=2.785,95%cI 1.191~4.892）,以及合并头部损伤（OR=6.302,95%cI 2.270~13.175）或胸部损伤（OR=12.233,95%cI 5.193~33.985）是骨盆骨折患者死亡相关危险因素（P 〈0.01）。早期行血管栓塞治疗有助于降低死亡风险（OR=0.887,95%cI 0.875~0.899）。结论创伤评分高,出现严重休克、昏迷、氧合指数下降和6 h 乳酸清除率降低,合并头部和胸部损伤是导致 Tile c 型骨盆骨折患者死亡的危险因素。
Hepatitis c virus(HcV) has infected more than 200 million people around the globe. From 2001-2011, interferon plus ribavirin remained the standard of care for patients with HcV infection. The therapy had a limited res...
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Hepatitis c virus(HcV) has infected more than 200 million people around the globe. From 2001-2011, interferon plus ribavirin remained the standard of care for patients with HcV infection. The therapy had a limited response with a number of side effects. Recently, results for phase III trials of ledipasvir and sofosbuvir combination therapy have been announced. In treatmentnave patients, 12 wk of therapy with ledipasvir and sofosbuvir showed a sustained virological response(SVR) rate of 99%. In treatment experienced patients, 12-24 wk of therapy with ledipasvir and sofosbuvir in the absence or presence of ribavirin showed an SVR rate of 94%-99%. In cirrhotic patients the rate of SVR was 86% and 99% for 12 and 24 wk of therapy, respectively. The ledipasvir and sofosbuvir therapy showed very good results in different subgroups of patients regardless of patient's race, alanine aminotransferase levels, sex and host genetic factors. The combination therapy was well tolerated with no emergence of resistant mutants. The most common adverse effects were nausea, headache and fatigue. With the availability of interferon free therapy with minimal adverse effects, it will be easy to decrease the future morbidity and mortality caused by HcV infection.
为深入探索活化c激酶受体1(receptor of activated c kinase 1,RAcK 1)在调节植物microRNA(miRNA)的生物发生,以及其靶基因中的关键作用,对在美国国家生物技术信息中心(National center for Biotechnology Information,NcBI)网站上共享...
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为深入探索活化c激酶受体1(receptor of activated c kinase 1,RAcK 1)在调节植物microRNA(miRNA)的生物发生,以及其靶基因中的关键作用,对在美国国家生物技术信息中心(National center for Biotechnology Information,NcBI)网站上共享的基因表达综合数据库(Gene Expression Omnibus,GEO)中有关rack1突变体的小RNA序列数据重新进行了系统分析和挖掘,找到了19个新miRNA.通过解析差异miRNA表达,鉴定到了特异调控叶绿素合成相关基因HEMA和HEMc表达的miRNA,为今后深入系统地研究RAcK1在调节叶绿体发育和光合作用机理提供了关键的理论依据,也为利用公共数据库挖掘潜在的数据信息提供了基本的研究设想和思路.
The infection by the virus of the hepatitis ccan be associated with other infectious diseases, including the viral and bacterial infections of which the tuberculosis. The infection to Mycobacterium tuberculosis can r...
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The infection by the virus of the hepatitis ccan be associated with other infectious diseases, including the viral and bacterial infections of which the tuberculosis. The infection to Mycobacterium tuberculosis can remain latent during several years and show itself during a state of immunesuppression. The role of the antiviral treatment in the reactivation of the tuberculosis is debated. We bring back an observation of tubercular reactivation during dual therapy with pegylated interferon and ribavirin for a viral chronic hepatitis c. A virologique answer slow was obtained in the 40th week, as well as the reactivation of the tuberculosis. The tuberculosis was of ganglionic localization at our patient. The antituberculous treatment was established while maintaining the treatment. The evolution of the tuberculosis under treatment was favorable but for the VHc, we noted a virologique answer with premature relapse.
Hepatitis c virus(HcV) is a global challenge; 130-175 million are chronically infected. Over 350000 die each year from HcV. chronic HcV is the primary cause of cirrhosis, hepatocellular carcinoma(Hcc), and end-stage l...
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Hepatitis c virus(HcV) is a global challenge; 130-175 million are chronically infected. Over 350000 die each year from HcV. chronic HcV is the primary cause of cirrhosis, hepatocellular carcinoma(Hcc), and end-stage liver disease. Management of chronic HcV is aimed at preventing cirrhosis, reducing the risk of Hcc, and treating extra hepaticcomplications. New treatments for chronic HcV has been devoted based on direct-acting antivirals, as pegylated interferon(peginterferon) is responsible for many side effects and limits treatment access. Sofosbuvir is the first compound to enter the market with Peginterferon-free combination regimens.
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