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DIScRETE APPLIED MATHEMATIcS 2020年 278卷 136-152页

作者： Krause, Philipp Klaus Larisch, Lukas Salfelder, Felix Albert Ludwigs Univ Freiburg Freiburg Germany King Abdullah Univ Sci & Technol Thuwal Saudi Arabia Univ Leeds Leeds W Yorkshire England

y Recently, approaches based on tree-decompositions (TDs) of control-flow graphs (cFGs) have been introduced for many classical problems in compiler construction. Some found practical use in SDcc, a mainstream c compiler for embedded systems. Using TD-based algorithms, SDcc generates faster and often smaller code for its target architectures than other compilers. The width of the TD crucially influences runtime, hence good algorithms computing TDs of small width are essential. The current standard approach to obtain TDs of cFGs is Thorup's heuristic, which was also used in SDcc. Thorup claims that his heuristic will give TDs of width at most 6 for cFGs from c code that contains no goto statements. We present a counter example resulting in a tree-width of 7. We show how to construct c code without goto statements for which the cFG has tree-width 3, but Thorup's heuristic will yield TDs of arbitrary width. We demonstrate how this flaw adversely affects the compilation of real-world code. We present a constructive proof giving a tight bound on the tree-width of cFGs of c programs. This corrects Thorup and shows the effect that goto has on the tree-width. We empirically evaluate various approaches to finding TDs of cFGs and their impact on compiler runtime and code quality in SDcc. Our research resulted in the replacement of the unconditional use of Thorup's heuristic by a better approach in SDcc 3.7.0, drastically reducing compiler runtime. (c) 2019 Elsevier B.V. All rights reserved.

关键词： c Tree-decomposition Tree-width Structured programs

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11c-Pittsburgh compound B and 18F-THK 5351 positron emission tomography brain imaging in cognitively normal individuals

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World Journal of Nuclear Medicine 2022年第2期20卷 133-138页

作者： chanisa chotipanich Attapon Jantarato Anchisa Kunawudhi Supaporn Kongthai chetsadaporn Promteangtrong National Cyclotron and PET Centre Chulabhorn Hospital Chulabhorn Royal Academy Bangkok Thailand

Abnormal beta-amyloid plaques and tau protein accumulation are the core pathologic features of Alzheimer's disease. However, the accumulation of these proteins is also common in cognitively normal elderly people. Therefore, this study is aimed to evaluate the amyloid and tau accumulation in the cognitively normal population. A preliminary prospective study was conducted on 24 cognitively normal individuals who underwent Pittsburgh compound B (

关键词： c Pittsburgh compound B F THK 5351 Alzheimer's disease cognitively normal individual positron emission tomography

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co3O4/NiO/c composites derived from zeolitic imidazolate frameworks (ZIFs) as high-performance anode materials for Li-ion batteries

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JOURNAL OF SOLID STATE ELEcTROcHEMISTRY 2020年第5期24卷 1133-1142页

作者： Li, Zhitong Zhao, Jian Nie, Jiajin Yao, Shaowei Wang, Jing Feng, Xiaoxin North China Univ Sci & Technol Coll Mat Sci & Engn Tangshan 063210 Peoples R China Key Lab Inorgan Mat Hebei Prov Tangshan 063210 Peoples R China

In this paper, co3O4/NiO/c composites were prepared by in situ co-precipitation and heat treatment with Zn/co-ZIF-derived N-doped porous carbon as carbon matrix. The structure and constituent of co3O4/NiO/c composites were detected by the X-ray diffraction (XRD), scanning electron microscope (SEM), transmission electron microscope (TEM), and other test methods. The result showed that Nico-LDH nanosheets grew evenly on the surface of porous carbon matrix. co3O4/NiO/c composites retained the dodecahedral shape of the carbon matrix. Electrochemical performance was investigated through electrochemical workstation and LAND-cT2001A battery test system. The results showed that the co3O4/NiO/c electrode has a higher initial discharge specific capacity of 1673.0 mA h g(-1) at 0.1 A g(-1), and it could still maintain the discharge specific capacity of 1167.8 mA h g(-1) after 100 cycles. The co3O4/NiO/c showed a high reversible capacity of 812.3 mA h g(-1) after 500 cycles at 0.5 A g(-1). The co3O4/NiO/c electrode exhibited excellent lithium storage performance, which can be attributed to the unique functionalities of the ternary components: NiO and co3O4 can guarantee high specific capacity, while the carbon matrix can improve the conductivity and the stability of the structure. Therefore, co3O4/NiO/c composite was expected to be anode material for lithium storage equipment.

关键词： co3O4 NiO c N-doped porous carbon Anode material Li-ion batteries

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Study on creep behavior and microstructure of a Fe-cr-Al-Nb-W ferrtic heat-resistant steel based on c, N and Al element control

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MATERIALS RESEARcH EXPRESS 2020年第5期7卷

作者： Zhang, Shanjun Shen, Junjie Kang, Hui Hu, Fuyong Tianjin Univ Technol Tianjin Key Lab Adv Mechatron Syst Design & Intel Sch Mech Engn Tianjin 300384 Peoples R China Tianjin Univ Technol Natl Demonstrat Ctr Expt Mech & Elect Engn Educ Tianjin 300384 Peoples R China

In this work, the effects of c, N, and Al on the microstructures and creep properties of Fe-cr-Al-Nb-W ferritic alloys were investigated through scanning electron microscopy, x-ray diffractometry, as well as uniaxial creep testing and hardness testing. The results demonstrated that the matrix of the Fe-cr-Al-Nb-W heat-resistant steel was ferrite, while the precipitation phases were Laves phases, M23c6 carbides and MX nitride phases. M23c6 and MX precipitated at grain interior, Laves phases precipitated at grain interior, grain boundary and around MX phases. c, N and Al affected microstructure and creep of heat-resistant steel. As the Al content increased or as N content decreased along with the c increase, the average diameter of the Laves phases, along with M23c6 and MX phase grain interior decrease. Moreover, the unit density increased and the phase spacing decreased, which led to the minimum creep rate decrease and creep rupture time increase. compared to M23c6, Laves and MX phases mainly affected the alloy creep strength. The decrease of Laves phase continuity coefficient (ratio of Laves phase particle spacing and size) on the grain boundary was conducive to the plasticity improvement of heat-resistant steel.

关键词： Laves phase ferrtic heat-resistant steel hardness creep strength c N and Al element control

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Fecl3/c as an efficient catalyst for Ferrier rearrangement of 3,4,6-tri-O-Benzyl-D-glucal

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JOURNAL OF cARBOHYDRATE cHEMISTRY 2020年第5-6期39卷 232-249页

作者： Mei, Yuling Dong, Youxian Li, Juan Zhang, Bo Sun, Guosheng Zhou, Jiafen Si, Wenshuai Han, Yiwen Wu, Zhenliang Zhang, Jianbo East China Normal Univ Sch Chem & Mol Engn 500 Dongchuan Rd Shanghai 200241 Peoples R China

Fecl3/c was used as an efficient and convenient promoter for glycosylation through Ferrier-type rearrangement of 3,4,6-tri-O-benzyl-D-glucal, which is a relatively unreactive substrate for this type of reaction. The method was applicable to a wide range of alcohols, especially phenols. A series of 2,3-unsaturated-O-glucosides were prepared efficiently (47-92%) by this method under mild conditions.

关键词： Fecl3 c Ferrier rearrangement promoter glycosylation 346-tri-O-benzyl-D-glucal

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Study of Metal-Induced Effects of cd, Sb and Zn on d.c./a.c. conduction and Photoconduction in Binary Se70Te30 Glass

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JOURNAL OF ELEcTRONIc MATERIALS 2020年第1期49卷 861-868页

作者： Saraswat, Shobhit Tomar, V. K. Mehta, N. Dahshan, A. GLA Univ Inst Engn & Technol Dept Elect & Commun Mathura India Banaras Hindu Univ Inst Sci Dept Phys Varanasi 221005 Uttar Pradesh India King Khalid Univ Fac Sci Dept Phys POB 9004 Abha Saudi Arabia Port Said Univ Fac Sci Dept Phys Port Said Egypt

This paper reports the temperature dependence of d.c. and a.c. conductivity in the glassy alloys of Se70Te30 and Se70Te28M2 (M = cd, Sb, Zn). The role of the cd, Sb, Zn elements as foreign atoms has been examined on the d.c./a.c. conduction and photoconduction in binary Se70Te30 glass. These multi-component chalcogenide glasses have been prepared by conventional, cost-effective and well-known melt-quench technique. Thermally activated a.c. conduction shows the presence of the compensation effect that is confirmed by the Meyer-Neldel relation between the associated activation energy and the pre-factor of a.c. conductivity. The metal-induced effects of cd, Sb, Zn on the photosensitivity of parent glass are also discussed.

关键词： Glass d c conductivity photosensitivity

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Fabrication of Zrc/ZrB₂/c composites Having High Mechanical Properties at Elevated Temperatures

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Materials Sciences and Applications 2022年第4期13卷 232-248页

作者： Kai Matsumoto Masaki Kato Ken Hirota Toshiyuki Nishimura Department of Molecular Chemistry & Biochemistry Faculty of Science & Engineering Doshisha University Kyotanabe Japan National Institute for Materials Science Tsukuba Japan

Ultra-high temperature ceramics (UHTcs) are most recently getting much attention for structural parts of hypersonic missiles with their cruising speed of more than Mach 5. Most of the UHTcs are poor sinterability carbides, nitrides, and borides. Therefore, they have been studied and developed for a long time. However, there are still many problems to solve. In this paper, based on the solid-state reaction presented as an equation of (x + y)·Zrc + 2·y·B → x·Zrc + y·ZrB₂ + y·c, three-phase Zrc/ZrB₂/c composites have been fabricated from Zrc and amorphous B powders using pulsed electric-current pressure sintering at 1373 to 2173 K for 6.0 × 10² s under 50 MPa in a vacuum. Zrc/ZrB2/c = 30/70/c~70/30/c vol% composites with the relative densities D_r of 96.6 to 98.7% were obtained at 2073 K. The 60/40/c vol% composite revealed high bending strength σ_b (554 MPa), Vickers hardness H_v (19.2 GPa) and moderate fracture toughness K_Ic (5.25 MPa·m^1/2) at room temperature. Furthermore, all composites showed elastic deformation up to 1873 K and revealed σ_b more than 600 MPa at this temperature, in addition, some composites showed higher σ_b than 900 MPa at the same temperature. These high mechanical behaviors are discussed with those of the simple binary Zrc/ZrB₂ composites which were fabricated under the same conditions except for their starting materials. The best mechanical properties of binary composites were σ_b (474 MPa), H_v (18.5 GPa), and K_Ic (4.45 MPa·m^1/2) at room temperature, and σ_b of 400 - 700 MPa at 1873 K. Overall, three-phase composites, nevertheless including soft carbon, have higher mechanical properties than the binary composites.

关键词： Zrc ZrB2 c composites Pulsed Electric-current Pressure Sintering Mechanical Properties

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comprehensive transcriptomic analysis reveals insights into the gill response to hypoxia and Poly I:c in Qihe crucian carp carassius auratus

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AQUAcULTURE REPORTS 2022年 24卷

作者： Di, Guilan Li, Hui Zhao, Yanjing Lin, Yan Lan, Di Kong, Xianghui chen, Xinhua Fujian Agr & Forestry Univ Inst Oceanol Coll Marine Sci Key Lab Marine Biotechnol Fujian Prov Fuzhou 350002 Peoples R China Henan Normal Univ Coll Fisheries Xinxiang 453007 Peoples R China Fuzhou Inst Technol Dept Biotechnol Fuzhou 350506 Peoples R China Qingdao Natl Lab Marine Sci & Technol Lab Marine Biol & Biotechnol Qingdao 266071 Peoples R China Henan Normal Univ Coll Fisheries 46 Jianshe Rd Xinxiang 453007 Peoples R China

Hypoxia occurrence is potentiated by eutrophication caused by human activities and it may be the most dramatically increasing environmental factor as a result of the climate change-led increasing temperatures. The crucian carp carassius auratus is an important aquaculture economical freshwater species and is also a potential model for the study of physiological adaptation. However, the transcriptomics and genomics data available for this species are still scarce. The gills of fish are the major organ of hypoxia and other stresses. In this study, we studied the effect of the exposure to hypoxia (1.0 mg O2/L for 7 d) and 2 mg/mL Poly I:c on the gene expression of the gills of carassius auratus using the Illumina sequencing platform. comparison of the gene expression levels between the experimental and control groups showed differentially expressed genes (DEGs). The DEGs were mainly annotated into glycolysis, oxidative phosphorylation and immune system categories based on the KEGG database. In glycolysis pathway, lactate dehydrogenase, malate dehydrogenase, glyceraldehyde 3-phosphate dehydrogenase, enolase and succinate dehydrogenase were identified. In addition, the DEGs were enriched in the immune-related pathway functions, including pattern recognition receptor (PRR), antigen processing and presentation, B cell and T cell receptor signaling pathways, natural killer (NK) cell mediated cytotoxicity, Fc gamma R-mediated phagocytosis, and the JAK-STAT, p53 and cytokines signaling pathways. This study also produced potential hypoxia biomarkers including FOS, JUN B, lysosomal acid lipase, and HIF-1 alpha. HIF-1 signaling pathway was significantly down-regulated after hypoxia and Poly I: c exposure. Hence, the data generated here may offer a valuable resource information for the further study of the immune response and also provide improved strategies against hypoxia and Poly I:c in teleost fish.

关键词： Transcriptome carassius auratus Hypoxia Gill Poly I c

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A cutting Force Prediction Model, Experimental Studies, and Optimization of cutting Parameters for Rotary Ultrasonic Face Milling of c/Sic composites

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APPLIED cOMPOSITE MATERIALS 2020年第4期27卷 407-431页

作者： Islam, Shafiul Yuan, Songmei Li, Zhen Beihang Univ Beijing Engn Technol Res Ctr High Efficient & Gre Sch Mech Engn & Automat Beijing 100191 Peoples R China

ceramic matrix composites of type c/Sic have great potential because of their excellent properties such as high specific strength, high specific rigidity, high-temperature endurance, and superior wear resistance. However, the machining of c/Sic is still challenging to achieve desired efficiency and quality due to their heterogeneous, anisotropic, and varying thermal properties. Rotary ultrasonic machining (RUM) is considered as a highly feasible technology for advanced materials. cutting force prediction in RUM can help to optimize input variables and reduce processing defects in composite materials. In this research, a mathematical axial cutting force model has been developed based on the indentation fracture theory of material removal mechanism considering penetration trajectory and energy conservation theorem for rotary ultrasonic face milling (RUFM) of c/Sic composites and validated through designed sets of experiments. Experimental results were found to be in good agreement with theoretically simulated results having less than 15% error. Therefore, this theoretical model can be effectively applied to predict the axial cutting forces during RUFM of c/Sic. The surface roughness of the workpiece materials was investigated after machining. The relationships of axial cutting force and surface roughness with cutting parameters, including spindle speed, feed rate, and cutting depth, were also investigated. In order to identify the influence of cutting parameters on the RUFM process, correlation analysis was applied. In addition, response surface methodology was employed to optimize the cutting parameters.

关键词： c Sic composites Rotary ultrasonic face milling A predictive cutting force model Surface roughness Optimization of cutting parameters

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Effect of the cagW-based gene vaccine on the immunologic properties of BALB/c mouse: an efficient candidate for Helicobacter pylori DNA vaccine

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JOURNAL OF NANOBIOTEcHNOLOGY 2020年第1期18卷 63-63页

作者： chehelgerdi, Mohammad Doosti, Abbas Islamic Azad Univ Shahrekord Branch Young Researchers & Elite Club Shahrekord Iran Islamic Azad Univ Shahrekord Branch Biotechnol Res Ctr Shahrekord Iran

Background Helicobacter pylori (H. pylori) infect more than half of the world population, and they cause different serious diseases such as gastric carcinomas. This study aims to design a vaccine on the basis of cagW against H. pylori infection. After pcDNA3.1 (+)-cagW-cS-NPs complex is produced, it will be administered into the muscles of healthy BALB/c mice in order to study the effect of this DNA vaccine on the interleukin status of mice, representing its effect on the immune system. After that, the results will be compared with the control groups comprising the administration of cagW-pcDNA3.1 (+) vaccine, the administration of chitosan and the administration of PBS in the muscles of mice. Methods The cagW gene of H. pylori was amplified by employing PcR, whose product was then cloned into the pcDNA3.1 (+) vector, and this cloning was confirmed by PcR and BamHI/EcoRV restriction enzyme digestion. cagW gene DNA vaccine was encapsulated in chitosan nanoparticles (pcDNA3.1 (+)-cagW-cS-NPs) using a complex coacervation method. The stability and in vitro expression of chitosan nanoparticles were studied by DNase I digestion and transfection, and the immune responses elicited in specific pathogen-free (SPF) mice by the pcDNA3.1 (+)-cagW-cS-NPs were evaluated. Apart from that, the protective potential pcDNA3.1 (+)-cagW-cS-NPs was evaluated by challenging with H. pylori. Results The pcDNA3.1 (+)-cagW-cS-NPs comprises cagW gene of H. pylori that is encapsulated in chitosan nanoparticles, produced with good morphology, high stability, a mean diameter of 117.7 nm, and a zeta potential of + 5.64 mV. Moreover, it was confirmed that chitosan encapsulation protects the DNA plasmid from DNase I digestion, and the immunofluorescence assay showed that the cagW gene could express in HDF cells and maintain good bioactivity at the same time. In comparison to the mice immunized with the control plasmid, in vivo immunization revealed that mice immunized with pcDNA3.1 (+)-cagW-NPs showe

关键词： BALB c chitosan nanoparticles DNA vaccine Helicobacter pylori Virulence factor

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