By using a recently developed computer program based on a correlation between methods to predict the elimination half-life and apparent volume of distribution of cimetidine and actual data from patients, ideal dosage ...
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By using a recently developed computer program based on a correlation between methods to predict the elimination half-life and apparent volume of distribution of cimetidine and actual data from patients, ideal dosage regimens were generated for patients with renal impairment and for geriatic patients, together with the corresponding maximum and minimum steady-state concentrations. Using the ideal dosage regimens, practical regimens with feasible dosing intervals of 6, 8 and 12 h were computed, which should result in therapeutic concentrations of 0.4-1.3 .mu.g/ml. For uremic patients and geriatric patients 75 yr old, it would be desirable to have an additional oral 100-mg dosage form.
A computer program package of 6 programs for vegetation classification is described. The package includes raw field-data input, automatic and user sequencing modes, final phytosociologic table and synoptic table prepa...
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A computer program package of 6 programs for vegetation classification is described. The package includes raw field-data input, automatic and user sequencing modes, final phytosociologic table and synoptic table preparation, which are camera-ready and also allow the user the option of ordinating by means of DECORANA.
This paper describes a heat pump transient analysis computer program (TRPUMP). It is based upon component mathematical models in lumped parametric form. It uses first-order differential equations to describe single- a...
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We propose a computer program allowing the automatic calculation of control charts for accuracy and precision. The calculated charts enable the analyst to control easily the daily results for a determined radioimmunoa...
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We propose a computer program allowing the automatic calculation of control charts for accuracy and precision. The calculated charts enable the analyst to control easily the daily results for a determined radioimmunoassay.
A method allowing the automatic determination of equilibrium constants and binding site concentrations for an immune serum composed of a series of homogeneous antibody subpopulations is described. The Scatchard plot c...
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A method allowing the automatic determination of equilibrium constants and binding site concentrations for an immune serum composed of a series of homogeneous antibody subpopulations is described. The Scatchard plot can be decomposed to its straight components corresponding to each antibody subpopulation.
A detailed discussion of the calculation of rate constants for hydrogen atom transfer reactions based on the BEBO method is presented. Linear transition state models are used. A computer program using this method for ...
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A detailed discussion of the calculation of rate constants for hydrogen atom transfer reactions based on the BEBO method is presented. Linear transition state models are used. A computer program using this method for determining rate constants is provided.
A FORTRAN IV program is presented which determines transition points for data that can be represented by a set of intersecting regression lines. Initial estimates are not required, and no specific spacing of the data ...
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A FORTRAN IV program is presented which determines transition points for data that can be represented by a set of intersecting regression lines. Initial estimates are not required, and no specific spacing of the data is needed. A spline function is used to reduce the large number of computational steps arising from complex linear models while an iterative least squares procedure is used to obtain the final solution. Examples of experimental and artificially generated data are presented along with an F -statistic for differences in slope at the transition point.
A detailed assessment of the frequency-domain approach normally used for evaluation of convertor harmonics is presented, limitations and inaccuracies are identified, and the need for an improved method is established....
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A detailed assessment of the frequency-domain approach normally used for evaluation of convertor harmonics is presented, limitations and inaccuracies are identified, and the need for an improved method is established. The theoretical basis of a new method, which simulates the individual switching processes within each convertor, is described. The method uses a modified state-variable approach to automatically formulate the 3-phase network equations, which are then linked with the convertor equations to give a time-domain solution. The computer program developed is capable of analysing power systems with interconnected components of any desired configuration, and the simultaneous operation of several convertor loads may be studied. When the time-domain solution reaches a periodic condition, the harmonic components are evaluated using a special-purpose Fourier-analysis program. The computed results of selected cases are presented to demonstrate the inherent accuracy of the method and to show its potential usefulness for other applications
The impacts on overall water supply resulting from different water management strategies for conjunctive use of surface and ground waters were studied for a 90-mile section of the South Platte River. A computer simula...
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The impacts on overall water supply resulting from different water management strategies for conjunctive use of surface and ground waters were studied for a 90-mile section of the South Platte River. A computer simulation study was conducted using data for the 10 years between 1952 and 1961. A drought period in the early '50s is included. The management strategies considered included: 1) lining some of the canals to improve conveyance efficiency; 2) improving water use efficiency on the farm; 3) pumping with relaxed restrictions; and, 4) a combination of all these strategies. The study indicates that the most effective strategy by far to alleviate the serious consequences of a drought on irrigated agriculture is to fully use the ground water reservoir capacity of the stream-aquifer system. Under increased pumping the stream and the aquifer quickly reach a new equilibrium and after two years there is no indication of a continued mining condition in the aquifer. This strategy is not only effective in the short term but also safe in the long *** impacts on overall water supply resulting from different water management strategies for conjunctive use of surface and ground waters were studied for a 90-mile section of the South Platte River. A computer simulation study was conducted. The management strategies considered included: lining some of the canals to improve conveyance efficiency; improving water use efficiency on the farm; pumping with relaxed restrictions; and, a combination of all these strategies. The study indicates that the most effective strategy by far to alleviate the serious consequences of a drought on irrigated agriculture is to fully use the ground water reservoir capacity of the stream-aquifer system. Under increased pumping the stream and the aquifer quickly reach a new equilibrium and after two years there is no indication of continued mining condition in the aquifer.
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