Computational modeling has been promulgated as a means of optimizing artificial bonetissue culturing ex vivo. In the present report, we show, as a proof-of-concept, that it is possible to model the exact microenviron...
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Computational modeling has been promulgated as a means of optimizing artificial bonetissue culturing ex vivo. In the present report, we show, as a proof-of-concept, that it is possible to model the exact microenvironment within the scaffolds while accounting for their architectural complexities and the presence of cells/tissues in their pores. Our results clearly indicate that image-based modeling has the potential to be a powerful tool for computer-assistedtissueengineering.
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