Based on the partition of parameter space, two algorithms for computing the rational univariate representation of zero-dimensional ideals with parameters are presented in the paper. Unlike the rational univariate repr...
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Microbes commonly organize into communities consisting of hundreds of species involved in complex interactions with each other. 16S ribosomal RNA (16S rRNA) amplicon profiling provides snapshots that reveal the phylog...
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Microbes commonly organize into communities consisting of hundreds of species involved in complex interactions with each other. 16S ribosomal RNA (16S rRNA) amplicon profiling provides snapshots that reveal the phylogenies and abundance profiles of these microbial communities. These snapshots, when collected from multiple samples, can reveal the co-occurrence of microbes, providing a glimpse into the network of associations in these communities. However, the inference of networks from 16S data involves numerous steps, each requiring specific tools and parameter choices. Moreover, the extent to which these steps affect the final network is still unclear. In this study, we perform a meticulous analysis of each step of a pipeline that can convert 16S sequencing data into a network of microbial associations. Through this process, we map how different choices of algorithms and parameters affect the co-occurrence network and identify the steps that contribute substantially to the variance. We further determine the tools and parameters that generate robust co-occurrence networks and develop consensus network algorithms based on benchmarks with mock and synthetic data sets. The Microbial Co-occurrence Network Explorer, or MiCoNE (available at ) follows these default tools and parameters and can help explore the outcome of these combinations of choices on the inferred networks. We envisage that this pipeline could be used for integrating multiple data sets and generating comparative analyses and consensus networks that can guide our understanding of microbial community assembly in different biomes.
We present a randomized parallel algorithm in the PRAM model for k-vertex connectivity. Given an undirected simple graph, our algorithm either finds a set of fewer than k vertices whose removal disconnects the graph o...
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Despite a strong theoretical foundation, empirical experiments reveal that existing domain generalization (DG) algorithms often fail to consistently outperform the ERM baseline. We argue that this issue arises because...
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For a prime p > 3 and a supersingular elliptic curve E defined over Fp2 with j(E) ∈/ {0, 1728}, consider an endomorphism α of E represented as a composition of L isogenies of degree at most d. We prove that the t...
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In this article, we aim to approximate a solution to the bilevel equilibrium problem (BEP) for short: find x¯ ∈ Sf such that g(x¯, y) ≥ 0, ∀y ∈ Sf, where Sf = {u ∈ K: f(u, z) ≥ 0, ∀z ∈ K}. Here, K is a...
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Given a hypergraph, computing its transversal hypergraph is a classical problem whose exact worst-case complexity is still unknown today. In this article, for Erdos and Renyi random hypergraph models, we compute the a...
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Composition is something we take for granted in classical algorithms design, and in particular, we take it as a basic axiom that composing "efficient" algorithms should result in an "efficient" alg...
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Brooks’ theorem states that all connected graphs but odd cycles and cliques can be colored with ∆ colors, where ∆ is the maximum degree of the graph. Such colorings have been shown to admit non-trivial distributed al...
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We investigate a difference-of-convex (DC) formulation where the second term is allowed to be weakly convex. We examine the precise behavior of a single iteration of the difference-of-convex algorithm (DCA), providing...
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