Systematic reviews have developed over the past 40 years as a method for integrating findings from the available studies relating to clinical problems and interventions into one publication. Systematic reviews employ ...
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Systematic reviews have developed over the past 40 years as a method for integrating findings from the available studies relating to clinical problems and interventions into one publication. Systematic reviews employ a variety of data analytic techniques including meta-analysis, which combines treatment effects across disparate studies in order to produce a truer estimate of treatment effect. The Cochrane Collaboration was established in order to facilitate access to high-quality evidence and specifies stringent guidelines for the production of systematic reviews. A Cochrane Systematic Review (CSR) includes consideration of the risk-of-bias of the selected studies in reaching conclusions. A recent CSR is used as an example to demonstrate the process of conducting a CSR, the dataanalytic methods employed and the assumptions made when employing these methods. There is a discussion of issues the reader will need to be aware of when considering the findings of a CSR and how this might differ from other systematic reviews including some consideration of how CSRs apply to the brain impairment literature.
Comprehending the performance bottlenecks at the core of the intricate hardware-software inter-actions exhibited by highly parallel programs on HPC clusters is crucial. This paper sheds light on the issue of automatic...
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Comprehending the performance bottlenecks at the core of the intricate hardware-software inter-actions exhibited by highly parallel programs on HPC clusters is crucial. This paper sheds light on the issue of automatically asynchronous MPI communication in memory-bound parallel programs on multicore clusters and how it can be facilitated. For instance, slowing down MPI processes by deliberate injection of delays can improve performance if certain conditions are met. This leads to the counter-intuitive conclusion that noise, independent of its source, is not always detrimental but can be leveraged for performance improvements. We employ phase-space graphs as a new tool to visualize parallel program dynamics. They are useful in spotting certain patterns in parallel execution that will easily go unnoticed with traditional tracing tools. We investigate five different microbenchmarks and applications on different supercomputer platforms: an MPI-augmented STREAM Triad, two implementations of Lattice-Boltzmann fluid solvers (D3Q19 and SPEChpc D2Q37), the LULESH and HPCG proxy applications.& COPY;2023 Elsevier B.V. All rights reserved.
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