When visualizing large datasets, an important goal is to emphasize data that is relevant to the task at hand. A common way of achieving this is to compute the relevance of the data using degree of interest (DOI) funct...
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(纸本)9798350325577
When visualizing large datasets, an important goal is to emphasize data that is relevant to the task at hand. A common way of achieving this is to compute the relevance of the data using degree of interest (DOI) functions, which apply a scenario-specific metric to quantify the data items according to their relevance to the users and their tasks. These DOI values can then be used to adjust the visual encoding through mechanisms like focus+context or information hiding. For datasets too large to be visualized at once, an alternative approach is to visualize it progressively in chunks, allowing analysts to reason about partial results and concluding their analysis much earlier than had they waited for all data. Combining the advantages of both approaches to tailor the visualization seems synergistic, yet, in practice turns out to be challenging, as DOI functions require the context of all data to produce useful values, requiring lengthy computations that break analysts' flow in progressive visualization. In this paper, we propose an approach for uniting DOI functions with progressive visualization. We first introduce a new model for quantifying the user interest in analysis scenarios where the data is only partially available, by computing the interest for available data and predicting it for the rest. We then propose regression trees for implementing this approach in practice and evaluate it in benchmarks. With DOI values now available for progressive visualization as well, our approach opens the door for tailoring the visualization of large datasets to the analysis task at interactive update rates.
Background: The interpretation of the results from genome-scale experiments is a challenging and important problem in contemporary biomedical research. Biological networks that integrate experimental results with exis...
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Background: The interpretation of the results from genome-scale experiments is a challenging and important problem in contemporary biomedical research. Biological networks that integrate experimental results with existing knowledge from biomedical databases and published literature can provide a rich resource and powerful basis for hypothesizing about mechanistic explanations for observed gene-phenotype relationships. However, the size and density of such networks often impede their efficient exploration and understanding. Results: We introduce a visual analytics approach that integrates interactive filtering of dense networks based on degree-of-interest functions with attribute-based layouts of the resulting subnetworks. The comparison of multiple subnetworks representing different analysis facets is facilitated through an interactive super-network that integrates brushing-and-linking techniques for highlighting components across networks. An implementation is freely available as a Cytoscape app. Conclusions: We demonstrate the utility of our approach through two case studies using a dataset that combines clinical data with high-throughput data for studying the effect of beta-blocker treatment on heart failure patients. Furthermore, we discuss our team-based iterative design and development process as well as the limitations and generalizability of our approach.
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