It has been shown that for obtaining hydrophobic coatings, it is reasonable to use fluoroalkylalkoxysilanes (fASs) with a longer fluoroalkyl chain than fAS-19, so that the f/Si molar ratio exceeds 5-6. It is proposed ...
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It has been shown that for obtaining hydrophobic coatings, it is reasonable to use fluoroalkylalkoxysilanes (fASs) with a longer fluoroalkyl chain than fAS-19, so that the f/Si molar ratio exceeds 5-6. It is proposed to purposefully change not only the chain length of oligomers, but also the structure of solutions from dilute colloidal solutions to structured gels, with the f/Si ratio being controlled. In the case of polycondensation of investigated fluoroalkylalkoxysilanes on a hydroxylated surface, a strong silicone framework is formed, which is chemically bonded to the surface and to fluoroalkyl chains oriented perpendicular to it.
Using the nonlinear autoregressive distributed lag (NARDL) method, the current study explores the effects of exchange rate variations on commodities trade between Pakistan and the United Kingdom. The current study con...
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Using the nonlinear autoregressive distributed lag (NARDL) method, the current study explores the effects of exchange rate variations on commodities trade between Pakistan and the United Kingdom. The current study contends that the limiting assumption of symmetry between the exchange rate and the trade flows may have hampered the empirical results, despite the fact that earlier studies primarily used the symmetric cointegration approach. from 1980 to 2020, the study examines the symmetric and asymmetries effects of exchange rate variations on 35 sectors in Pakistan that import from the UK and 35 industries that export to the UK. The findings suggest that there is evidence of a considerable influence of asymmetric exchange rate variations on trade flows in both the short and long term in over half of the importing and exporting industries that participate in trade with the UK. By highlighting the significance of taking into account asymmetry in the analysis and exposing the sector-specific effects of exchange rate changes on trade flows, the study adds to the body of current work.
Darunavir/cobicistat/emtricitabine/tenofovir alafenamide (D/C/f/TAf) 800/150/200/10 mg is a fixed-dose combination (fDC) for the treatment of HIV-1 infection in adults and adolescents weighing 40 kg or greater. This P...
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Darunavir/cobicistat/emtricitabine/tenofovir alafenamide (D/C/f/TAf) 800/150/200/10 mg is a fixed-dose combination (fDC) for the treatment of HIV-1 infection in adults and adolescents weighing 40 kg or greater. This Phase 1, randomized, open-label, 2-treatment, 2-sequence, 4-period replicate crossover study (NCT04661397) evaluated the pivotal bioequivalence of a pediatric D/C/f/TAf 675/150/200/10-mg fDC compared with coadministration of the separate commercially available formulations in healthy adults under fed conditions. During each period, participants received either a single oral dose of D/C/f/TAf 675/150/200/10-mg fDC (test) or a single oral dose of darunavir 600 and 75 mg, cobicistat 150 mg, and emtricitabine/tenofovir alafenamide 200/10-mg fDC (reference). Thirty-seven participants were randomly assigned to one of 2 treatment sequence groups: test-reference-reference-test or reference-test-test-reference, with 7 days or more washout between periods. The 90% confidence intervals of the geometric mean ratios for maximum plasma concentration, area under the concentration-time curve from time zero to last measurable concentration, and area under the concentration-time curve extrapolated to infinity for darunavir, cobicistat, emtricitabine, and tenofovir alafenamide fell within conventional bioequivalence limits (80%-125%). No Grade 3/4 adverse events, serious adverse events, or deaths occurred. In conclusion, administration of D/C/f/TAf 675/150/200/10-mg fDC was bioequivalent to coadministration of the separate commercially available formulations.
fusarium graminearum is among the most virulent pathogens attacking wheat plants and significantly lowering its production globally. The present work aims to shed light on the interactions between two priming solution...
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fusarium graminearum is among the most virulent pathogens attacking wheat plants and significantly lowering its production globally. The present work aims to shed light on the interactions between two priming solutions, calcium (Ca) or salicylic acid (SA), and f. graminearum inoculation depending on the growth rate, physiological attributes, and molecular responses in wheat seedlings. In a pot experiment, f. graminearum-pre-inoculated or inoculum-free sandy soil was used to germinate wheat kernels after priming them for 12 h in distilled water, 5-mM CaCl2, or 0.05-mM SA. The results demonstrated that f. graminearum inoculation decreased growth rate and chlorophyll content, but promoted carotenoids, stress markers (electrolytes leakage, lipid peroxidation, protein oxidation, hydrogen peroxide, and hydroxyl radical), antioxidant molecules (AsA, phenols, and flavonoids), osmolytes (GB, amino acids, and proline), and the antioxidant enzymes (CAT, GPX, SOD, PPO, and PAL). Additionally, the fungal infestation boosted the expression of CAT, GR, PR4, MT, and PCS genes. However, presoaking wheat kernels in Ca or SA solutions has contributed to mitigating the negative effects offungal inoculation by restoring growth rate, chlorophyll content, and antioxidant capacity. It has also decreased the induced oxidative stress and downregulated the gene expression off. graminearum-inoculated wheat seedlings. Consequently, by minimizing the negative repercussions off. graminearum infestation, priming with Ca or SA could be used to appropriately stimulate growth and readjust the oxidative status of wheat seedlings.
To investigate fluoride (f)-induced intestine barrier damage and the role of estrogen deficiency in this progress, a rat model of estrogen deficiency was established through bilateral surgical removal of ovaries. The ...
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To investigate fluoride (f)-induced intestine barrier damage and the role of estrogen deficiency in this progress, a rat model of estrogen deficiency was established through bilateral surgical removal of ovaries. The f exposure model was then continued by adding sodium fluoride (0, 25, 50, and 100 mg/L, calculated on a fluorine ion basis) to drinking water for 90 days. Afterward, intestinal mucosal structure, barrier function, and inflammatory cytokines were evaluated. The results showed that excessive f decreased the developmental parameters (crypt depth) of the cecum and rectum and inhibited the proliferation capacity of the intestinal epithelia, which are more obvious in the state of estrogen deficiency. The distribution of goblet cells and glycoproteins in the intestinal mucosa decreased with the increase in f concentration, and estrogen deficiency led to a further decline, especially in the rectum. Using the immunofluorescence method, the study showed that excessive f caused interleukin-17A (IL-17A) significantly decrease in the cecum and increase in the rectum. Meanwhile, f treatment remarkably upregulated the expression of intestinal IL-1 beta, IL-23, and IL-22, while the level of IL-6 was downregulated. In addition, estrogen deficiency increased IL-1 beta, IL-6, IL-23, and IL-22, but decreased IL-17A expression in the cecum and rectum. Collectively, f exposure damaged intestinal morphological structure, inhibited epithelial cell proliferation and mucus barrier function, and resulted in the disturbance of T helper (Th) 17 cell-related cytokines expression. Estrogen deficiency may further aggravate f-induced damage to the cecum and rectum.
Purpose: To report a case of a patient with a large thoracoabdominal aortic aneurysm (TAAA) extent V treated with a custom-made fenestrated and branched endovascular repair (f/B-EVAR) after a failed and incomplete att...
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Purpose: To report a case of a patient with a large thoracoabdominal aortic aneurysm (TAAA) extent V treated with a custom-made fenestrated and branched endovascular repair (f/B-EVAR) after a failed and incomplete attempt of a Sandwich repair technique. Report: An 83-year-old patient was referred to our department after a failed attempt at endovascular repair of type V TAAA with a sandwich technique. The celiac trunk was inadvertently covered with the first endograft and a covered long superior mesenteric artery stent was placed and left facing upward inside the aorta. We performed a staged repair, by first catheterizing and stenting the celiac trunk and bringing it under and inside the main aortic endograft. In interval, a f/B-EVAR was performed using a bimodular custom-made device (CMD) with a proximal 2 branch module for the celiac trunk and superior mesenteric artery and distal module with fenestrations for both renal arteries. The intervention was successful, and the follow-up was uneventful at 6 months. Conclusions: Re-intervention after failed endovascular attempts of TAAA repair are technically challenging and require advanced endovascular techniques. The ability to construct CMDs allowed to extend repair to our patient which had severe anatomical constraints for other techniques.
PurposeThis study was to investigate the regulation of sulfur status in continuous-cropping soybean soil by funneliformis mosseae and Thiobacillus thioparus and promote the absorption of sulfur in soybean. To explore ...
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PurposeThis study was to investigate the regulation of sulfur status in continuous-cropping soybean soil by funneliformis mosseae and Thiobacillus thioparus and promote the absorption of sulfur in soybean. To explore the interactions among f. mosseae, T. thioparus and soybean plants, this study laid a theoretical foundation for the application off. mosseae and T. thioparus as biological agents in agricultural *** culture, a two-compartment system and shake-flask culture were used in the experiment. Using f. mosseae and T. thioparus as experimental inoculants, the effects off. mosseae on sulfur oxide of T. thioparus and their interaction on the growth of soybean plants were studied from the aspects of soil sulfur content, sulfur functional genes and the growth of soybean and sulfur-oxidizing *** f. mosseae and T. thioparus inoculation significantly increased the abundance of sulfur-oxidizing bacteria and available sulfur content in the soil, stimulated the expression of sulfate transporter genes in soybean roots, and promoted the absorption of sulfur nutrients in soybean. f. mosseae stimulated the expression of the T. thioparus sulfur-oxidation gene and enhanced the sulfur-oxidation capacity, while T. thioparus enhanced f. mosseae colonization of soybean roots. Thus, f. mosseae and T. thioparus promoted soil sulfur cycling and sulfate transport in soybean roots, which proved that f. mosseae could effectively improve the sulfur-oxidation capacity of T. *** inoculation with f. mosseae and T. thioparus significantly promoted soybean plant growth and increased soil sulfur utilization.
This work evaluated the development of beverage from ficus capensis and Justicia secunda leaves composite using response surface methodology three-level factorial design gas chromatography-mass spectrophotometry. fres...
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This work evaluated the development of beverage from ficus capensis and Justicia secunda leaves composite using response surface methodology three-level factorial design gas chromatography-mass spectrophotometry. fresh leaves off. capensis and J. secunda were processed into tea. The results indicated the optimal extracts blends of 48% off. capensis and 52% of J. secunda. The iron content was 489.11 mg/g;flavonoid content, 83.64 mg QE/100 g;vitamin C content, 1003.14 mg/100 g;and pyridoxine content, 357.31 mg/100 g. Alkaloid profile showed tetrahydrorhombiofoline (35%), columbamine (20.10%), laudanosine (11.50%), salsoline (8.22%), methylcobalamin (7.98%), quinine (5.89%), and quinidine (3.21%). Other phytocompounds with bioactive characteristics include 11-octadecenoic acid, methyl ester (32.43 g/100 g);hexadecanoic acid, methyl ester (16.69 g/100 g);9,12-octadecadienoic acid (Z,Z)-, methyl ester (12.81 g/100 g);(E)-9-octadecenoic acid, ethyl ester (9.71 g/100 g);hexadecanoic acid, ethyl ester (5.86 g/100 g);methyl stearate (4.62);linoleic acid, ethyl ester (4.62 g/100 g), octadecanoic acid, ethyl ester (1.84 g/100 g);and octasiloxane, 1,1,3,3,5,5,7,7,9,9,11,11,13,13,15,15-hexadecamethyl (0.19 g/100 g) with good sensory attributes. The optimized tea from f. capensis and J. secunda is rich in health-supporting substances and could be employed in promoting healthy living.
In this work we prove a fourier-Bros-Iagolnitzer (f.B.I.) characterisation for Gevrey vectors on hypo-analytic structures and we analyse the main differences of Gevrey regularity and hypo-analyticity concerning the f....
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In this work we prove a fourier-Bros-Iagolnitzer (f.B.I.) characterisation for Gevrey vectors on hypo-analytic structures and we analyse the main differences of Gevrey regularity and hypo-analyticity concerning the f.B.I. transform. We end with an application of this characterisation on a propagation of Gevrey singularities result for solutions of the nonhomogeneous system associated with the hypo-analytic structure for analytic structures of tube type.
作者:
Cheng, Yu -MingWang, Chia-ChiTungs Taichung MetroHarbor Hosp
Dept Gastroenterol & Hepatol Taichung Taiwan Tzu Chi Univ
Taipei Tzu Chi Hosp Buddhist Tzu Chi Med Fdn Dept Gastroenterol Hualien Taiwan Tzu Chi Univ
Sch Med Hualien Taiwan Tzu Chi Univ
Taipei Tzu Chi Hosp Buddhist Tzu Chi Med Fdn Med Dept 289 Jianguo RdXindian Area New Taipei City 23142 Taiwan Tzu Chi Univ
Sch Med 289 Jianguo RdXindian Area New Taipei City 23142 Taiwan
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